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Condition: Atrial Fibrillation
Procedure: Heart Valve Surgery

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Total 444 results found since Jan 2013.

Oral anti-Xa anticoagulation after Trans-Aortic Valve Implantation for Aortic Stenosis: The randomized ATLANTIS trial
Conclusions ATLANTIS tests the superiority of an apixaban-based strategy versus the recommended standard of care strategy to reduce the risk of post-TAVR thromboembolic and bleeding complications in an all comer population.
Source: American Heart Journal - March 10, 2018 Category: Cardiology Source Type: research

Use of an Automated Suture Fastening Device in Minimally Invasive Aortic Valve Replacement.
CONCLUSIONS: In minimally invasive aortic valve replacement, the Cor-Knot device was associated with reduced aortic cross-clamp time while providing equivalent clinical outcomes. Larger studies are needed to confirm efficacy, safety, and cost-effectiveness of the Cor-Knot device in minimally invasive aortic valve surgery. PMID: 29501643 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - March 1, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Beute TJ, Orem MD, Schiller TM, Goehler M, Parker J, Willekes CL, Timek T Tags: Ann Thorac Surg Source Type: research

Type II Minimal ‐Invasive Extracorporeal Circuit for Aortic Valve Replacement: A Randomized Controlled Trial
Abstract Extracorporeal circulation triggers systemic inflammatory response and coagulation disorders which may lead to unfavorable clinical outcome. A type II minimally‐invasive extracorporeal circuit (MiECC) is a closed system with markedly reduced artificial surface as compared to conventional extracorporeal circuits (CECC). The aim of this study was to investigate and compare inflammatory responses, complement activation and selected clinical end‐points in isolated surgical aortic valve replacement (SAVR) performed with a type II MiECC circuit or a CECC. Fifty patients were prospectively randomized to MiECC or CECC...
Source: Artificial Organs - February 12, 2018 Category: Transplant Surgery Authors: Erich Gygax, Hans ‐Ulrich Kaeser, Mario Stalder, Brigitta Gahl, Robert Rieben, Thierry Carrel, Gabor Erdoes Tags: Main Text Source Type: research

Antithrombotic therapy after TAVR.
Abstract Transvascular aortic valve replacement (TAVR) has emerged as a treatment option in patients with severe aortic stenosis who are inoperable and has recently been evaluated in patients with intermediate surgical risk. The number of procedures is increasing worldwide in parallel with the demographic changes in industrial countries. The risk for cerebral embolism is of main concern and represents a major determinant for prognosis and quality of live after TAVR. The empiric antithrombotic therapy consists of dual antiplatelet therapy (DAPT); however the risk-benefit of this approach is lacking evidence from ra...
Source: Current Vascular Pharmacology - January 17, 2018 Category: Drugs & Pharmacology Authors: Geisler T, Droppa M, Mueller K, Borst O Tags: Curr Vasc Pharmacol Source Type: research

Comparing Methods for Cardiac Output: Intraoperatively Doppler-Derived Cardiac Output Measured With 3-Dimensional Echocardiography Is Not Interchangeable With Cardiac Output by Pulmonary Catheter Thermodilution.
CONCLUSIONS: Despite low bias, the wide limits of agreement of Doppler-derived CO by 3D TEE compared to CO by thermodilution will limit clinical application and can therefore not be considered interchangeable with CO obtained by thermodilution. The lack of agreement is not explained by lack of agreement of the 3D technique. PMID: 29324489 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - January 9, 2018 Category: Anesthesiology Authors: Graeser K, Zemtsovski M, Kofoed KF, Winther-Jensen M, Nilsson JC, Kjaergaard J, Møller-Sørensen H Tags: Anesth Analg Source Type: research

Nonvitamin K Antagonist Oral Anticoagulants Use in Patients with Atrial Fibrillation and Bioprosthetic Heart Valves/Prior Surgical Valve Repair: A Multicenter Clinical Practice Experience
Semin Thromb Hemost DOI: 10.1055/s-0037-1615261This is an observational study to investigate the efficacy and safety of nonvitamin K antagonist oral anticoagulants (NOACs) in atrial fibrillation (AF) patients with bioprosthetic valves or prior surgical valve repair in clinical practice. A total of 122 patients (mean age: 74.1 ± 13.2; 54 females) with bioprosthetic heart valve or surgical valve repair and AF treated with NOACs were included in the analysis. The mean CHA2DS2-VASc (Congestive heart failure, Hypertension, Age >75 years, Diabetes mellitus, prior Stroke or transient ischemic attack, Vascular disease) and...
Source: Seminars in Thrombosis and Hemostasis - January 5, 2018 Category: Hematology Authors: Russo, Vincenzo Attena, Emilio Mazzone, Carmine Esposito, Francesca Parisi, Valentina Bancone, Ciro Rago, Anna Nigro, Gerardo Sangiuolo, Raffaele D' Onofrio, Antonio Tags: Original Article Source Type: research

1-Year Clinical Outcomes in Women After Transcatheter Aortic Valve Replacement: Results From the First WIN-TAVI Registry
Conclusions Intermediate to high-risk women enrolled in this first ever all-women contemporary TAVR registry experienced a 1-year VARC-2 composite efficacy endpoint of 16.5%, with a low incidence of 1-year mortality and stroke. Prior revascularization and EuroSCORE I were independent predictors of the VARC-2 efficacy endpoint, whereas EuroSCORE I, baseline atrial fibrillation, and prior percutaneous coronary intervention were independent predictors of the 1-year death or stroke.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - January 1, 2018 Category: Cardiology Authors: Chieffo, A., Petronio, A. S., Mehilli, J., Chandrasekhar, J., Sartori, S., Lefevre, T., Presbitero, P., Capranzano, P., Tchetche, D., Iadanza, A., Sardella, G., Van Mieghem, N. M., Meliga, E., Dumonteil, N., Fraccaro, C., Trabattoni, D., Mikhail, G., Shar Tags: Focus on Cardiovascular Outcomes Among Women Source Type: research

Sex-Specific Outcomes of Transcatheter Aortic Valve Replacement With the SAPIEN 3 Valve: Insights From the PARTNER II S3 High-Risk and Intermediate-Risk Cohorts
Conclusions The study found no apparent sex-specific differences in survival or stroke in this trial of TAVR. This may reflect the changing demographic of patients enrolled, use of newer-generation valves with more sizes available, and more accurate valve sizing techniques.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - January 1, 2018 Category: Cardiology Authors: Szerlip, M., Gualano, S., Holper, E., Squiers, J. J., White, J. M., Doshi, D., Williams, M. R., Hahn, R. T., Webb, J. G., Svensson, L. G., Kirtane, A. J., Cohen, D. J., Douglas, P. S., Alu, M. C., Crowley, A., Tuzcu, E. M., Makkar, R. R., Herrmann, H. C., Tags: Focus on Cardiovascular Outcomes Among Women Source Type: research

Treatment and discharge patterns among patients hospitalized with non-valvular atrial fibrillation transitioning from the inpatient to outpatient setting.
CONCLUSIONS: Most patients hospitalized for NVAF were discharged to home support, and the majority did not have OAC treatment during hospitalization or the 30 days post-discharge. Additional investigation should be conducted on trends beyond 30 days post hospitalization and the reasons for not receiving anticoagulation therapy in patients at moderate to severe risk of stroke or systemic embolism. Helping to avoid preventable strokes is an important goal for public health. PMID: 29235900 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - December 15, 2017 Category: Research Tags: Curr Med Res Opin Source Type: research

Transcatheter vs surgical aortic ‐valve replacement in low‐ to intermediate‐surgical‐risk candidates: A meta‐analysis and systematic review
The American and European expert documents recommend transcatheter aortic valve replacement (TAVR) for inoperable or high‐surgical‐risk patients with severe aortic stenosis. In comparison, efficacy of TAVR is relatively less studied in low‐ to intermediate‐surgical‐risk patients. We sought to discover whether TAVR can be as effective as surgical aortic valve replacement (SAVR) in low‐ to intermediate‐surgical‐risk candidates. Four randomized clinical trials (RCTs) and 8 prospective matched studies were selected using PubMed/MEDLINE, Embase, and Cochrane Library (inception: March 2017). Results were reported...
Source: Clinical Cardiology - November 23, 2017 Category: Cardiology Authors: Safi U. Khan, Ahmad N. Lone, Muhammad A. Saleem, Edo Kaluski Tags: REVIEW Source Type: research

Mitral valve pressure gradient after percutaneous mitral valve repair: every beat counts
Abstract A patient presented with symptoms of decompensated heart failure 2 months after percutaneous mitral valve (MV) repair. Echocardiography demonstrated impaired left ventricular function with elevated MV pressure gradients and pulmonary pressures during rapid atrial fibrillation. Heart rate control was achieved by implantation of a biventricular pacemaker with subsequent His‐bundle ablation because atrial fibrillation was refractory to medical treatment. During biventricular pacing at different rates (50–110 b.p.m.), heart rate correlated positively with both MV mean pressure gradient and global longitudinal st...
Source: ESC Heart Failure - November 23, 2017 Category: Cardiology Authors: Daniel Lavall, Bruno Scheller, Christian Werner, Axel Buob, Felix Mahfoud Tags: Case Report Source Type: research

Efficacy and Efficiency of Perioperative Stellate Ganglion Blocks in Cardiac Surgery: A Pilot Study
Nationally, postoperative atrial fibrillation (POAF) occurs in up to 40% of patients after coronary artery bypass grafting (CABG), 50% of patients after valve surgery, 64% of patients after mitral valve and CABG, and 49% after aortic valve replacement.1 Atrial fibrillation worsens a patient ’s hemodynamic status and increases the risk of congestive heart failure, embolic events, and longer intensive care unit stays, leading to increased patient morbidity and strain on financial resources. In the United States, POAF carries a higher risk of stroke, worsened survival, and an additional 4.9 days and $10,000 to $11,500 in hospital stay costs.
Source: Journal of Cardiothoracic and Vascular Anesthesia - November 20, 2017 Category: Anesthesiology Authors: Christopher W. Connors, Wendy Y. Craig, Scott A. Buchanan, Justin M. Poltak, James B. Gagnon, Craig S. Curry Tags: Letter to the Editor Source Type: research

Long ‐term outcomes for different surgical strategies to treat left ventricular outflow tract obstruction in hypertrophic cardiomyopathy
ConclusionSeptal myectomy is a safe procedure resulting in symptomatic improvement in the majority of patients. The annual incidence of non‐fatal disease‐related complications after surgical treatment of LVOTO is relatively high. Patients who underwent MV replacements had poorer outcomes with less symptomatic benefit in spite of a similar reduction in LVOT gradients.
Source: European Journal of Heart Failure - November 16, 2017 Category: Cardiology Authors: Richard Collis, Oliver Watkinson, Constantinos O'Mahony, Oliver P. Guttmann, Antonis Pantazis, Maria Tome ‐Esteban, Victor Tsang, Venkatachalam Chandrasekaran, Christopher G.A. McGregor, Perry M. Elliott Tags: Research Article Source Type: research

Transcatheter or surgical aortic valve replacement in patients with advanced kidney disease: A propensity score –matched analysis
ConclusionsIn patients with advanced kidney disease, SAVR was associated with higher mortality and higher periprocedural complications, as compared with TAVR. Thus, benefits of TAVR could be extended in patients with advanced kidney disease who cannot undergo surgery.
Source: Clinical Cardiology - October 1, 2017 Category: Cardiology Authors: Rajkumar Doshi, Jay Shah, Vaibhav Patel, Varun Jauhar, Perwaiz Meraj Tags: CLINICAL INVESTIGATIONS Source Type: research

Comparison of del Nido Cardioplegia With Blood Cardioplegia in Adult Combined Surgery
Conclusions: The DNS can be used as an alternative to BS in adult concomitant aortic valve replacement + CABG surgery. This supports our hypothesis that in this specific setting, DNS provides comparable myocardial protection as BS, with possibly shorter cardiopulmonary bypass and cross-clamp times.
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - September 1, 2017 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research