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Procedure: Lung Transplant

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Total 372 results found since Jan 2013.

GIMVECH: A Novel Risk Score for Stroke in the Perioperative Post Transplant Period
This study was undertaken to identify risk factors in this population during the perioperative post transplant period.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: N. Nair, S. Yang, E. Gongora Source Type: research

Low Dose tPA as a Therapeutic Strategy in Suspected Pump Thrombosis in HeartMate II
Tissue plasminogen activator (tPA) is a known treatment for DVT and thromboembolic stroke. Our study aim was to determine the safety and efficacy of a low dose tPA protocol in suspected pump thrombosis in HMII.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: A.S. Cruz-Solbes, M.I. Achi, J. Amione-Guerra, E. Karanja, B. Trachtenberg, A. Bhimaraj, J. Estep, G. Torre-Amione, I. Hussain, M. Park, B. Bruckner, A. Guha Source Type: research

Management of RVAD Thrombosis in Biventricular HVAD Supported Patients
Pump thrombosis confers significant morbidity and mortality in left ventricular assist device (LVAD) supported patients. Particularly in HVAD, therapeutic approaches including thrombolysis, or adjusting anticoagulation have been recommended as initial treatment but are associated with hemorrhagic stroke and death. Conversely, device exchange has been recommended as a preferred choice with low morbidity-mortality. Biventricular support (BIVAD) utilizing 2 HVAD systems has been proven as a novel way to manage critically ill individuals with biventricular failure.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: J. Silva Enciso, M. Brambatti, H. Tran, G.V. Pretorius, E. Adler Source Type: research

RVOT-VTI/PASP Is a Novel Noninvasive Parameter of Pulmonary Artery Compliance and Improves After Treatment with Pulmonary Hypertension-Specific Therapy
Pulmonary artery compliance (PAC) is an independent predictor of mortality in patients with pulmonary hypertension (PH). We have previously shown that the ratio of echocardiography derived right ventricular outflow tract velocity time integral (RVOT-VTI; an estimate of stroke volume) to pulmonary artery systolic pressure (PASP) correlates with PAC measured by right heart catheterization. We sought to determine whether PH-specific therapy improves PAC in patients with pulmonary arterial hypertension (PAH).
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: M.S. Tanna, A. Fox, G.S. Troutman, P.T. Bhattacharya, J.N. Menachem, F. Mao, E.Y. Birati, P.R. Forfia, A. Vaidya, J.A. Mazurek Source Type: research

Effect of a Multifaceted Team Management Approach on Survival and Stroke Rates in Heartmate 2 Recipients
We report the effect of a comprehensive HM II management strategy on survival and stroke rates.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: U. Jorde, N. Siddiqi, A. Luke, D.B. Sims, O. Saeed, S.R. Patel, S. Murthy, J. Shin, S. Watts, E. Borukhov, S. Madan, S. Thompson, R. Bello, S. Forest, S. Vukelic, C. Nucci, S. Rangasamy, D. Goldstein Source Type: research

Characteristics and Outcome of Patients with Stroke After Lung Transplant Surgery in the Lung Allocation Score Era
With introduction of lung allocation (LAS) in 2005, increasingly sicker patients are being transplanted every year. The current study was conducted to determine the incidence of stroke early after lung transplantation (LT), describe the recipient characteristics that are independently associated with it and evaluate its impact on 1 year survival.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: A. Banga, M. Mohanka, S. Bollineni, J. Mullins, V. Kaza, F. Torres Source Type: research

Does Type of Mechanical Circulatory Support Influence Stroke Risk in the Perioperative Post Transplant Period?
This study was undertaken to assess if the type of circulatory support device used has an impact on stroke risk in this population.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: N. Nair, S. Yang, E. Gongora Source Type: research

(1205) Does Stroke in the Perioperative Post Cardiac Transplant Period Impact Survival?
This study addresses the effect of stroke on overall survival in this population.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: N. Nair, S. Yang, E. Gongora Source Type: research

Paradoxical Mechano-Energetic Costs of Acute Mechanical Intra-Ventricular Unloading: A Key to Understand Myocardial Recovery with Left-Ventricular Mechanical Support?
This study tested such hypothesis by assessing the acute effects of LVAD support on systemic hemodynamics, left-ventricular (LV) mechano-energetics and myocardial oxygen consumption (MVO2) in vivo.
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: S. Bennett, C.L. del Rio, J. Noel-Morgan, E. Geist, Y. Ueyama, E. Ferris, B. Youngblood, P.I. McConnell Source Type: research

Lung Transplantation and the Routine Use of Cardiopulmonary Bypass and Median Sternotomy: Experience at the Ochsner Multi-Organ Transplant Institute.
CONCLUSION: Patients' early outcomes appear to have improved with the use of CPB and median sternotomy; however, 3-year survival is similar to the non-CPB group. Technical benefits of CPB with median sternotomy include decreased warm ischemia time during graft implantation, controlled hemodynamics and reperfusion, avoidance of single-lung ventilation of a freshly implanted graft, and the option to open the left atrium for implantation of a venous cuff without using a clamp. The surgical exposure facilitated by CPB with median sternotomy for lung transplantation appears to be a safe and feasible approach for lung transplant...
Source: Ochsner Journal - March 25, 2017 Category: Journals (General) Tags: Ochsner J Source Type: research

Surgical occlusion of the left atrial appendage and thromboembolic complications in patients with left ventricular assist devices
Thromboembolic complications (TECs) are major adverse events for patients supported by left ventricular assist devices (LVADs). Despite anti-coagulation, TECs such as stroke or pump thrombosis occur in 6.5% of patients.1 Risk of TECs increases with longer duration of device support, and the risk is likely greater in patients receiving LVADs as destination therapy. Surgical or percutaneous occlusion of the left atrial appendage (LAA) reduces TECs in patients with atrial fibrillation.2,3 The LAA may also be a source of thromboembolism for patients with systolic heart failure, including patients in sinus rhythm.
Source: The Journal of Heart and Lung Transplantation - January 29, 2017 Category: Transplant Surgery Authors: Rebecca S. Lewis, Lian Wang, Kateri J. Spinelli, Gary Y. Ott, Jacob Abraham Tags: Research Correspondence Source Type: research

Surgical occlusion of the left atrial appendage and thromboembolic complications in left ventricular assist device patients
Thromboembolic complications (TEC) are major adverse events for patients supported by left ventricular assist devices (LVADs). Despite anticoagulation, TEC such as stroke or pump thrombosis still occur in 6.5% of patients.1 Risk of TEC increases with longer duration of device support and is likely a greater risk in destination therapy patients. Surgical or percutaneous occlusion of the left atrial appendage (LAAO) reduces TEC in patients with atrial fibrillation.2,3 The LAA may also be a source of thromboembolism for systolic heart failure patients, even in sinus rhythm.
Source: The Journal of Heart and Lung Transplantation - January 29, 2017 Category: Transplant Surgery Authors: Rebecca S. Lewis, Lian Wang, Kateri J. Spinelli, Gary Y. Ott, Jacob Abraham Source Type: research

Reverse Right Ventricular Remodeling After Lung Transplantation in Patients With Pulmonary Arterial Hypertension Under Combination Therapy of Targeted Medical Drugs.
CONCLUSIONS: Although severe RV dysfunction and dilation were observed in patients with end-stage PAH despite combination therapy of PAH-targeted drugs, RV function and morphology were improved after reduction of RV pressure load by LTx. PMID: 28100891 [PubMed - as supplied by publisher]
Source: Circulation Journal - January 17, 2017 Category: Cardiology Authors: Sarashina T, Nakamura K, Akagi S, Oto T, Oe H, Ejiri K, Nakagawa K, Nishii N, Matsubara H, Kobayashi M, Morimatsu H, Miyoshi S, Ito H Tags: Circ J Source Type: research

Risk Factors, Mortality and Timing of Ischemic and Hemorrhagic Stroke with Left Ventricular Assist Devices
Stroke is a major cause of mortality following left ventricular assist device (LVAD) placement.
Source: The Journal of Heart and Lung Transplantation - December 22, 2016 Category: Transplant Surgery Authors: Jennifer A. Frontera, Randall Starling, Sung-Min Cho, Amy S. Nowacki, Ken Uchino, M. Shazam Hussain, Maria Mountis, Nader Moazami Tags: Original Clinical Science Source Type: research

Risk factors, mortality, and timing of ischemic and hemorrhagic stroke with left ventricular assist devices
Stroke is a major cause of mortality after left ventricular assist device (LVAD) placement.
Source: The Journal of Heart and Lung Transplantation - December 22, 2016 Category: Transplant Surgery Authors: Jennifer A. Frontera, Randall Starling, Sung-Min Cho, Amy S. Nowacki, Ken Uchino, M. Shazam Hussain, Maria Mountis, Nader Moazami Tags: Original Clinical Science Source Type: research