Filtered By:
Procedure: Lung Transplant
This page shows you your search results in order of date. This is page number 5.
Order by Relevance | Date
Total 372 results found since Jan 2013.
FDA Approves Expanded Peripheral Artery Disease (PAD) Indication for XARELTO ® (rivaroxaban) Plus Aspirin to Include Patients After Lower-Extremity Revascularization (LER) Due to Symptomatic PAD
RARITAN, N.J., August 24, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved an expanded peripheral artery disease (PAD) indication for the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) to include patients following recent lower-extremity revascularization (LER) due to symptomatic PAD. The approval is based on data from the Phase 3 VOYAGER PAD study. With this approval, XARELTO® is the first and only therapy indicated to help reduce the risks of major cardiovascular (CV) events in p...
Source: Johnson and Johnson - August 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Predicting the survivals and favorable neurologic outcomes after targeted temperature management by artificial neural networks
CONCLUSIONS: The ANN-based models achieved good performance to predict the survival and favorable neurologic outcomes after TTM. The models proposed have clinical value to assist in decision-making.PMID:34330620 | DOI:10.1016/j.jfma.2021.07.004
Source: J Formos Med Assoc - July 31, 2021 Category: General Medicine Authors: Wei-Ting Chiu Chen-Chih Chung Chien-Hua Huang Yu-San Chien Chih-Hsin Hsu Cheng-Hsueh Wu Chen-Hsu Wang Hung-Wen Chiu Lung Chan Source Type: research
Janssen Submits New Drug Application to U.S. FDA for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, June 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the use of XARELTO® (rivaroxaban) in pediatric patients. The NDA seeks two pediatric indications: treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients aged birth to less than 18 years of age after at least five days of initial parenteral anticoagulant treatment; and thromboprophylaxis (prevention of blood clots) in patients aged 2 years and older with congenita...
Source: Johnson and Johnson - June 23, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Cerebral Vasoreactivity in HeartMate 3 Patients
While rates of stroke have declined with the HeartMate3 (HM3) continuous flow (CF) left ventricular assist device (LVAD), the impact of non-pulsatile flow and artificial pulse physiology on cerebrovascular function is not known. We hypothesized that improved hemodynamics and artificial pulse physiology of HM3 patients would augment cerebrovascular metabolic reactivity (CVR) compared with HeartMate II (HMII) CF-LVAD and heart failure (HF) patients.
Source: The Journal of Heart and Lung Transplantation - May 21, 2021 Category: Transplant Surgery Authors: Eric J. St öhr, Ruiping Ji, Koichi Akiyama, Giulio Mondellini, Lorenzo Braghieri, Alberto Pinsino, John R. Cockcroft, Melana Yuzefpolskaya, Amrin Amlani, Veli K. Topkara, Hiroo Takayama, Yoshifumi Naka, Nir Uriel, Koji Takeda, Paolo C. Colombo, Barry J. Tags: Original Research Article Source Type: research
Late-Breaking Data at ACC.21 Show XARELTO ® (rivaroxaban) Plus Aspirin Significantly Reduced Total Ischemic Events in Peripheral Artery Disease (PAD) Patients After Lower-Extremity Revascularization
RARITAN, N.J., May 16, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today presented new data from the Phase 3 VOYAGER PAD study which showed XARELTO® (rivaroxaban) (2.5 mg twice daily) in combination with aspirin (100 mg once daily) consistently reduced severe vascular events in patients with peripheral artery disease (PAD) after lower-extremity revascularization (LER) compared to aspirin alone regardless of whether it was the first, second, third, or subsequent event. The primary results of VOYAGER PAD showed that XARELTO® plus aspirin reduced first events by 15 percent among patients with PAD ...
Source: Johnson and Johnson - May 16, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Prehabilitation Coming of Age: IMPLICATIONS FOR CARDIAC AND PULMONARY REHABILITATION
While cardiac and pulmonary rehabilitation programs traditionally involve exercise therapy and risk management following an event (eg, myocardial infarction and stroke), or an intervention (eg, coronary artery bypass surgery and percutaneous coronary intervention), prehabilitation involves enhancing functional capacity and optimizing risk profile prior to a scheduled intervention. The concept of prehabilitation is based on the principle that patients with higher functional capabilities will better tolerate an intervention, and will have better pre- and post-surgical outcomes. In addition to improving fitness, prehabilitati...
Source: Journal of Cardiopulmonary Rehabilitation - April 30, 2021 Category: Rehabilitation Tags: Invited Review Source Type: research
Risk Factors and Prognostic Implications of Perioperative Stroke after Heart Transplantation: An Analysis of the United Network for Organ Sharing Database 2009-2019
The purpose of our study was to evaluate risk factors and prognostic implications of perioperative stroke in heart transplantation.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: T. Kitai, T. Okamoto, A. Briasoulis, H. Niikawa, K. McCurry, P. Alvarez Tags: (248) Source Type: research
Low Left Ventricular Stroke Work Index is Associated with a Poor Prognosis in LVAD Patients
Hemocompatibility-related adverse events (HRAE) are thought to be largely driven by the pump-patient interaction. We hypothesized that patients with left ventricular assist devices (LVADs) with low left ventricular stroke work index (LVSWI), and thus less native contribution to total flow, would have more adverse clinical outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: A.J. Kanelidis, T. Miller, M. Belkin, U. Siddiqi, D. Rogers, N. Uriel, T. Song, T. Ota, S. Kalantari, N. Sarswat, A. Nguyen, B.B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (226) Source Type: research
Hyperhomocysteinemia and Oxidative Stress May Predict the Risk of Stroke in Patients Supported by Continuous Flow Left Ventricular Assist Devices
Stroke is one of the leading complications during CF-LVAD support. The purpose of this observational study was to investigate the temporal relationship of circulating homocysteine (Hcy) and oxidative stress as potential markers to identify CF-LVAD patients at risk for developing postoperative strokes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: N.K. Mondal, H.K. Lamba, S.I. Hudson, C. Hochman-Mendez, A.E. Shafii, G. Loor, A. Mattar, R.K. Ghanta, O. Frazier, K.K. Liao Tags: (386) Source Type: research
Prolonged Circulatory Arrest is Not Associated with Stroke or Mortality after Pulmonary Thromboendarterectomy
Patients with chronic thromboembolic pulmonary hypertension (CTEPH) frequently present with extensive distal clot burden, which adds complexity to pulmonary thromboendarterectomy (PTE). Complete endarterectomy often necessitates prolonged periods of hypothermic circulatory arrest (HCA), the ramifications of which are poorly understood. Objectives were to describe the association of HCA time with post-operative neurologic complications, operative mortality and other major morbidity after PTE.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: J.L. Armstrong, A.M. Vekstein, A. Seas, C.M. Wojnarski, A.M. Ganapathi, J.C. Haney Tags: (433) Source Type: research
Improvement in Right Ventricular Stroke Work Index in Cardiogenic Shock Associated with Excellent Durable Left Ventricular Assist Implantation Results
Cardiogenic shock results from inadequate cardiac output to satisfy organ perfusion with potential need for pharmacologic and mechanical circulatory support for survival. Impella 5.0 insertion is used as a rescue device and bridge to durable mechanical circulatory support. We sought to evaluate changes in right ventricular parameters in patients bridged with Impella 5.0 undergoing durable left ventricular device implantation (LVAD).
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: M.P. Rogers, B.D. Mackie, R.L. Hooker Tags: (447) Source Type: research
Incidence, Predictors and Outcomes of Stroke Following Cardiac Transplantation
Stroke after heart transplantation (HT) is a major cause of morbidity and mortality. Less is known about the risk factors associated with stroke in the current era of increasing HT being performed in older patients and with advances in immunosuppressive (IS) therapies. We aimed to determine the incidence, predictors and outcomes of stroke after HT.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: H. Alnsasra, R. Asleh, N. Kumar, T. Toya, C. Lopez, W.K. Kremers, B. Edwards, R.C. Daly, S.S. Kushwaha Tags: (548) Source Type: research
Percent Increase in Left Ventricular Stroke Work Index and Right Ventricular Stroke Work Index after Milrinone Infusion Predicts Escalation of Therapy and Mortality
We hypothesized that changes in biventricular function would approximate myocardial reserve and predict outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: U.A. Siddiqi, M. Belkin, S. Kalantari, A. Kanelidis, T. Miller, N. Sarswat, A. Nguyen, B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (638) Source Type: research
Prognostic Role of Simultaneous Assessment of Biventricular Function Using Left Ventricular Stroke Work Index and Right Ventricular Stroke Work Index
We hypothesized that simultaneous assessment of biventricular function could predict clinical outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: U.A. Siddiqi, M. Belkin, S. Kalantari, A. Kanelidis, T. Miller, N. Sarswat, A. Nguyen, B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (632) Source Type: research
