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Overweight teen boys have increased risk of stroke in later life
Conclusion The findings of this large longitudinal cohort study seem to demonstrate a link between being overweight aged 20 and an increased risk of stroke. This risk was regardless of whether the boy had been overweight aged 8 or not. There seemed to be no increased risk for boys who were overweight aged 8 but were a normal weight by the age of 20. The study was conducted before the obesity epidemic, and might be even more relevant today. But there are a number of considerations to take into account before we draw any conclusions: Participants were followed up until they were 52-68, so all the strokes occurred at a r...
Source: NHS News Feed - June 29, 2017 Category: Consumer Health News Tags: Obesity Pregnancy/child Source Type: news

Mechanical thrombectomy for acute ischemic stroke in pregnancy using the penumbra system
Sanjith Aaron, NK Shyamkumar, Sunithi Alexander, P Suresh Babu, AT Prabhakar, Vinu Moses, TV Murthy, Mathew AlexanderAnnals of Indian Academy of Neurology 2016 19(2):261-263Even though intravenous thrombolysis with tissue plasminogen activator (IV tPA) is the standard of care in acute ischemic stroke, its use in pregnancy is not clearly defined. Mechanical thrombectomy devices can be an option; however, literature on the use of such mechanical devices in stroke in pregnancy is lacking. Here we describe two cases that developed acute embolic stroke during pregnancy who were successfully treated by mechanical clot retrieval ...
Source: Annals of Indian Academy of Neurology - May 11, 2016 Category: Neurology Authors: Sanjith AaronNK ShyamkumarSunithi AlexanderP Suresh BabuAT PrabhakarVinu MosesTV MurthyMathew Alexander Source Type: research

'More adults should be taking statins,' says NICE
Conclusion Despite somewhat hysterical media coverage to the contrary ("millions more to be given statins," according to the Daily Express), nobody will be forced to take statins. If your GP does recommend statins, you should ask them to explain the benefits and risks for you personally of starting statin treatment. You may want to find out more about statins before making up your mind – the NHS Choices Health A-Z information on statins is a good place to start. If you do experience troublesome side effects while taking statins, contact your GP or the doctor in charge of your care. It could be the case that a...
Source: NHS News Feed - July 18, 2014 Category: Consumer Health News Tags: Heart/lungs Medication QA articles Source Type: news

Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk Neuroscience
Females show a varying degree of ischemic sensitivity throughout their lifespan, which is not fully explained by hormonal or genetic factors. Epidemiological data suggest that sex-specific life experiences such as pregnancy increase stroke risk. This work evaluated the role of parity on stroke outcome. Age-matched virgin (i.e., nulliparous) and multiparous...
Source: Proceedings of the National Academy of Sciences - July 11, 2017 Category: Science Authors: Rodney M. Ritzel, Anita R. Patel, Monica Spychala, Rajkumar Verma, Joshua Crapser, Edward C. Koellhoffer, Anna Schrecengost, Evan R. Jellison, Liang Zhu, Venugopal Reddy Venna, Louise D. McCullough Tags: PNAS Plus Source Type: research

Long-Term Exposure to Transportation Noise in Relation to Development of Obesity —a Cohort Study
Conclusion: Our results link transportation noise exposure to development of obesity and suggest that combined exposure from different sources may be particularly harmful. https://doi.org/10.1289/EHP1910 Received: 17 March 2017 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 20 November 2017 Address correspondence to A. Pyko, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden. Telephone: 46(0) 852487561. Email: Andrei.pyko@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP1910). The authors declare they have no actual or potential competing fina...
Source: EHP Research - November 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Iron Metabolism and Brain Development in Premature Infants
Yafeng Wang1,2,3, Yanan Wu2, Tao Li1,2,3, Xiaoyang Wang2,4 and Changlian Zhu2,3* 1Department of Neonatology (NICU), Children’s Hospital Affiliated Zhengzhou University, Zhengzhou, China 2Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China 3Department of Clinical Neuroscience, Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden 4Department of Physiology, Sahlgrenska Academy, Institute of Neuroscience and Physiology, University of Got...
Source: Frontiers in Physiology - April 24, 2019 Category: Physiology Source Type: research

What parents need to know about pain in newborns
Just because newborn babies can’t tell you they feel pain doesn’t mean they don’t feel pain. They do. And parents can help. We tend to think that newborns are too little to really experience pain, and that if they do experience it, they soon forget it. However, research has shown that, indeed, babies do experience pain — and that repeated painful experiences in the newborn period can lead to both short- and long-term problems with development, emotions, and responses to stress. This is particularly a problem for babies who need many medical procedures after they are born, such as premature babies, babies with certa...
Source: New Harvard Health Information - January 26, 2016 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Family Planning and Pregnancy Parenting Source Type: news

FDA warns parents about arsenic in rice cereal
Follow me at @drClaire For years, rice cereal has been a go-to for parents when they start their babies on solid foods. It’s time to change that. In 2012, the Consumer Products Safety Commission (CPSC) issued a report warning about high levels of inorganic arsenic in rice and rice products. Rice plants are particularly good at absorbing arsenic from the soil, in particular because they grow in a lot of water. Inorganic arsenic is a common ingredient in pesticides and other products used in farming, and can linger in the soil for a long time after it is used. It can be poisonous. In high doses it is lethal, but even small...
Source: New Harvard Health Information - April 5, 2016 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Parenting Safety Source Type: news

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis – endorsed by the European Academy of Neurology
ConclusionsMulticentre observational and experimental studies are needed to increase the level of evidence supporting recommendations on the diagnosis and management of CVT.
Source: European Journal of Neurology - August 20, 2017 Category: Neurology Authors: J. M. Ferro, M. ‐G. Bousser, P. Canhão, J. M. Coutinho, I. Crassard, F. Dentali, M. Minno, A. Maino, I. Martinelli, F. Masuhr, D. Aguiar de Sousa, J. Stam, Tags: Guidelines Source Type: research

Antiphospholipid antibody syndrome: The difficulties of diagnosis
This article reviews screening, diagnosis, and management of APS with a focus on the prevention of long-term complications.
Source: Journal of the American Academy of Physician Assistants - November 30, 2017 Category: Primary Care Tags: CME: Hematology Source Type: research

Urine Arsenic and Arsenic Metabolites in U.S. Adults and Biomarkers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: A Cross-Sectional Study
Conclusion: In a cross-sectional study of U.S. adults, we observed some positive associations of uAs and toenail As concentrations with biomarkers potentially relevant to CVD pathogenesis and inflammation, and evidence of a higher capacity to metabolize inorganic As was negatively associated with a marker of oxidative stress. https://doi.org/10.1289/EHP2062 Received: 14 April 2017 Revised: 13 November 2017 Accepted: 15 November 2017 Published: 15 December 2017 Address correspondence to S.F. Farzan, 2001 N. Soto St., Los Angeles, CA, 90032. Telephone: (323)-442-5101; Email: sffarzan@usc.edu Supplemental Material is ava...
Source: EHP Research - December 16, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Pregnancy and cardio-embolic stroke: To recanalize or not ?
Ayush Agarwal, Priyanka Sehrawat, Venugopalan Y Vishnu, Ajay Garg, Mamta B Singh, Vinay Goyal, MV Padma SrivastavaAnnals of Indian Academy of Neurology 2022 25(5):985-988
Source: Annals of Indian Academy of Neurology - October 31, 2022 Category: Neurology Authors: Ayush Agarwal Priyanka Sehrawat Venugopalan Y Vishnu Ajay Garg Mamta B Singh Vinay Goyal MV Padma Srivastava Source Type: research

The 3rd Beijing Forum of Evidence-Based Medicine and 2023 Cochrane China Network Symposium successfully held
Cochrane China recently hosted a virtual event for the evidence-based medicine community that brought together many of its partners, local expertise, and international speakers. Here the team provides an overview of who was involved and what was covered at the event.  The3rd Beijing forum of evidence-based medicine and Cochrane China Network  Symposium was successfully held virtually on January 15th, 2023. The host of this conference wereCochrane China Network and Beijing GRADE Center. The organizers are Centre for Evidence-based Chinese Medicine, Beijing University of Chinese Medicine, affiliate of the Cochrane China Ne...
Source: Cochrane News and Events - February 17, 2023 Category: Information Technology Authors: Muriah Umoquit Source Type: news