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Nutrition: Sodium Chloride

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Total 383 results found since Jan 2013.

The cost-effectiveness of government actions to reduce sodium intake through salt substitutes in Vietnam
ConclusionThis research shows that all three modelled salt substitution strategies would be good value for money relative to no intervention in Vietnam. The subsidised alternative would require the highest level of government investment; however the implementation costs will be exceeded by healthcare savings assuming a reasonable time horizon is considered.
Source: Archives of Public Health - March 11, 2021 Category: International Medicine & Public Health Source Type: research

Long noncoding RNA SNHG1 protects brain microvascular endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury by sponging miR-298 and upregulating SIK1 expression
CONCLUSION: SNHG1 knockdown enhanced OGD/R-induced injury in bEnd3 cells by regulating miR-298/SIK1 axis, which might provide promising therapeutic target for treatment of ischemic stroke.PMID:33677804 | DOI:10.1007/s10529-021-03096-z
Source: Biotechnology Letters - March 7, 2021 Category: Biotechnology Authors: Xinyu Zhou Bingchao Xu Yan Gu Niu Ji Pin Meng Lingdan Dong Source Type: research

The endogenous and exogenous brain-derived neurotrophic factor plays pivotal roles in the pathogenesis of stroke onset in high salt-loaded hypertensive rats
Exp Gerontol. 2021 Feb 17;147:111286. doi: 10.1016/j.exger.2021.111286. Online ahead of print.ABSTRACTBrain-derived neurotrophic factor (BDNF) is known to have neuroprotective effects on multiple neurovascular diseases especially poststroke recovery. On the other hand, BDNF reported to increase blood pressure (BP) which is one of the major risk factors for stroke onset. To clarify the conflicting effects on stroke onset, we examined the expression of endogenous BDNF in relation to stroke onset. In addition, we explored the effect of exogenous central BDNF against stroke onset and all-cause mortality as the primary endpoint...
Source: Experimental Gerontology - February 20, 2021 Category: Geriatrics Authors: Yu Hasegawa Yushin Takemoto Kenyu Hayashi Koki Kameno Shokei Kim-Mitsuyama Source Type: research

The endogenous and exogenous brain-derived neurotrophic factor plays pivotal roles in the pathogenesis of stroke onset in high salt-loaded hypertensive rats.
Abstract Brain-derived neurotrophic factor (BDNF) is known to have neuroprotective effects on multiple neurovascular diseases especially poststroke recovery. On the other hand, BDNF reported to increase blood pressure (BP) which is one of the major risk factor for stroke onset. To clarify the conflicting effects on stroke onset, we examined the expression of endogenous BDNF in relation to stroke onset. In addition, we explored the effect of exogenous central BDNF against stroke onset and all-cause mortality as the primary endpoint and BP as the secondary object in hypertensive rats with high-salt diet. In experime...
Source: Experimental Gerontology - February 17, 2021 Category: Geriatrics Authors: Hasegawa Y, Takemoto Y, Hayashi K, Kameno K, Kim-Mitsuyama S Tags: Exp Gerontol Source Type: research

A Method for Estimating 24-hour Urinary Sodium Excretion by Casual Urine Specimen in Chinese Hypertensive Patients.
CONCLUSION: Sun_C method may prove a reasonable method to estimate the daily dietary sodium intakes (particularly in the range of 6 g/d - 12 g/d of NaCl) in Chinese hypertensive patients using spot urine measurements. As the amount of data increases in the future, the performance of our formulae will be further improved. PMID: 33491075 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - January 25, 2021 Category: Cardiology Authors: Sun Y, Wang H, Liang H, Yuan Y, Shu C, Zhang Y, Zhu Y, Yu M, Hu S, Sun N Tags: Am J Hypertens Source Type: research

Impact of salt intake reduction on CVD mortality in Costa Rica: A scenario modelling study
The objective of this study was to estimate the impact of reducing salt intake on CVD mortality in Costa Rica using a scenario simulation model. The Preventable Risk Integrated ModEl (PRIME) was used to estimate the number of deaths that would be averted or delayed in the Costa Rican population by following the national and the international guidelines to reduce salt consumption, according to two scenarios: A) 46% reduction and B) 15% reduction, both at an energy intake of 2171 kcal. The scenarios estimated that between 4% and 13%, respectively, of deaths due to CVD would be prevented or postponed. The hig hest percentages...
Source: PLoS One - January 12, 2021 Category: Biomedical Science Authors: Jaritza Vega-Solano Source Type: research

Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats.
Abstract Non-traditional work schedules, such as shift work, have been associated with numerous health issues including cardiovascular and metabolic disease. These work schedules can chronically misalign environmental timing cues with internal circadian clock systems in the brain and in peripheral organs, leading to dysfunction of those systems and their associated biological processes. Environmental circadian disruption in the kidney may be an important factor in the increased incidence of hypertension and adverse health outcomes in human shift workers. The relationship between renal rhythmicity and injury resili...
Source: Am J Physiol Renal P... - December 28, 2020 Category: Urology & Nephrology Authors: Hill AM, Crislip GR, Stowie A, Ellis I, Ramsey A, Castanon-Cervantes O, Gumz ML, Davidson AJ Tags: Am J Physiol Renal Physiol Source Type: research

Food as Prevention – Rising to Nutritional Challenges
Mothers and their children gather at a community nutrition centre in the little village of Rantolava, Madagascar, to learn more about a healthy diet. Credit: Alain Rakotondravony/IPSBy Gabriele RiccardiNAPLES, Italy, Nov 25 2020 (IPS) The risks factors contributing to the dramatic rise in non-communicable diseases (NCDs) in recent decades have been known for a long time but the Covid-19 pandemic has brutally exposed our collective failure to deal with them. Reporting on the findings of the latest Global Burden of Disease Study, The Lancet warns of a “perfect storm” created by the interaction of the highly infectious C...
Source: IPS Inter Press Service - Health - November 25, 2020 Category: International Medicine & Public Health Authors: Gabriele Riccardi Tags: Development & Aid Economy & Trade Featured Food Security and Nutrition Food Sustainability Global Headlines Health Humanitarian Emergencies Inequity Poverty & SDGs TerraViva United Nations Barilla Center for Food and Nutrition Foun Source Type: news

The Role of Dietary Salt and Alcohol Use Reduction in The Management of Hypertension.
Authors: Wake AD Abstract INTRODUCTION: Despite the improved treatment protocol of hypertension, the magnitude of the disease and its related burden remains raised. Hypertension makes up the leading cause of stroke, kidney disease, arterial disease, eye disease, and cardiovascular disease (CVD) growth. AREAS COVERED: This review provides the overview of the role of dietary salt and alcohol use reduction in the management of hypertension, brief history of alcohol, the vascular endothelium functions, the effects of alcohol use on blood pressure (BP), the mechanisms of alcohol, brief history of salt, the effects o...
Source: Expert Review of Cardiovascular Therapy - November 18, 2020 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Comparison of the Characteristics and Risk Factors of Carotid Atherosclerosis in High Stroke Risk Populations Between Urban and Rural Areas in North China
Conclusion: This study suggests that risk factors for carotid atherosclerosis differ between urban and rural populations in North China.
Source: Frontiers in Neurology - November 9, 2020 Category: Neurology Source Type: research