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Total 1014 results found since Jan 2013.

The Watchman device for preventing stroke in patients with atrial fibrillation
This article discusses the Watchman device, a left atrial appendage occlusion device that provides an option for patients with contraindications for anticoagulation.
Source: Journal of the American Academy of Physician Assistants - October 1, 2021 Category: Primary Care Tags: Review Article Source Type: research

6.17 Transcranial Photobiomodulation (tPBM) Is a Noninvasive Form of Brain Stimulation That Can Improve Language and Social Skills Acquisition in Children With Autism Spectrum Disorder
The objective of this presentation is to demonstrate if transcranial photobiomodulation (tPBM) is an effective treatment modality to improve language and communication skills in children with autism spectrum disorder (ASD). In recent pilot studies, tPBM has been shown to be effective for stroke, traumatic brain injury (TBI), and depression. Furthermore, recently, 2 small pilot studies showed that tPBM can reduce symptoms of ASD. We hypothesized that children with ASD will demonstrate improvement in communication skills and language acquisition with this experimental treatment.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - October 1, 2021 Category: Psychiatry Authors: Yuli Fradkin, Eugenia Steingold, Katya Sverdlov, Sergey Burd Source Type: research

Ministernotomy for Aortic Valve Replacement Versus Conventional Sternotomy, a Choice for a Better outcome
Conclusion​ Ministernotomy Aortic valve replacement was found to be a safe procedure​ compared to full sternotomy approach. Patients who had their surgery through the mini approach had less amount of blood loss, blood transfusion requirements, ventilation time which all led to less duration of ICU and hos pital stay, resulting in a better outcome for the .patients
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

The Association Between Sleep and Health-Related Quality of Life in Stroke Survivors
The American Academy of Sleep Medicine recommends adults engage in a minimum of 7 hours of sleep per 24 hour interval to optimize health. Stroke recovery, with its foundations in neuroplasticity, is impacted by sleep. The purpose of this study was to examine stroke survivor data from the 2018 Behavioral Risk Factor Surveillance System (BRFSS), and to compare self-reported measures of physical health (PH) and mental health (MH) for those individuals who met sleep guidelines to those who did not.
Source: Archives of Physical Medicine and Rehabilitation - September 28, 2021 Category: Rehabilitation Authors: David Levine, Cindy Poole, Christine Hostetler, Kendall Jeter, Cara Kingrea, Kloe Kukta, Nancy Fell Tags: Research Poster 1709896 Source Type: research

Emerging role of the ketogenic dietary therapies beyond epilepsy in child neurology
Dipti Kapoor, Divyani Garg, Suvasini SharmaAnnals of Indian Academy of Neurology 2021 24(4):470-480 Ketogenic dietary therapies (KDTs) have been in use for refractory paediatric epilepsy for a century now. Over time, KDTs themselves have undergone various modifications to improve tolerability and clinical feasibility, including the Modified Atkins diet (MAD), medium chain triglyceride (MCT) diet and the low glycaemic index treatment (LGIT). Animal and observational studies indicate numerous benefits of KDTs in paediatric neurological conditions apart from their evident benefits in childhood intractable epilepsy, including...
Source: Annals of Indian Academy of Neurology - September 20, 2021 Category: Neurology Authors: Dipti Kapoor Divyani Garg Suvasini Sharma Source Type: research

Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans Neuroscience
Restoration of human brain function after injury is a signal challenge for translational neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for intensive motor training after stroke: near-full recovery is attained if task-specific motor training occurs during this sensitive window. We extended these findings to adult humans...
Source: Proceedings of the National Academy of Sciences - September 20, 2021 Category: Science Authors: Alexander W. Dromerick, Shashwati Geed, Jessica Barth, Kathaleen Brady, Margot L. Giannetti, Abigail Mitchell, Matthew A. Edwardson, Ming T. Tan, Yizhao Zhou, Elissa L. Newport, Dorothy F. Edwards Tags: Neuroscience Biological Sciences Source Type: research

Pediatric COVID-19 Cases Are Surging, Pushing Hospitals —and Health Care Workers—to Their Breaking Points
Aug. 20 was a good day in the pediatric intensive care unit at Children’s Hospital New Orleans. Carvase Perrilloux, a two-month-old baby who’d come in about a week earlier with respiratory syncytial virus and COVID-19, was finally ready to breathe without the ventilator keeping his tiny body alive. “You did it!” nurses in PPE cooed as they removed the tube from his airway and he took his first solo gasp, bare toes kicking. Downstairs, Quintetta Edwards was preparing for her 17-year-old son, Nelson Alexis III, to be discharged after spending more than two weeks in the hospital with COVID-19—fir...
Source: TIME: Health - August 26, 2021 Category: Consumer Health News Authors: Jamie Ducharme/New Orleans, La. Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

An outer-pore gate modulates the pharmacology of the TMEM16A channel Pharmacology
TMEM16A Ca2+-activated chloride channels are involved in multiple cellular functions and are proposed targets for diseases such as hypertension, stroke, and cystic fibrosis. This therapeutic endeavor, however, suffers from paucity of selective and potent modulators. Here, exploiting a synthetic small molecule with a biphasic effect on the TMEM16A channel, anthracene-9-carboxylic...
Source: Proceedings of the National Academy of Sciences - August 19, 2021 Category: Science Authors: Ria L. Dinsdale, Tanadet Pipatpolkai, Emilio Agostinelli, Angela J. Russell, Phillip J. Stansfeld, Paolo Tammaro Tags: Pharmacology Biological Sciences Source Type: research

Vitamin C and scar strength: analysis of a historical trial and implications for collagen-related pathologies
Am J Clin Nutr. 2021 Aug 16:nqab262. doi: 10.1093/ajcn/nqab262. Online ahead of print.ABSTRACTA double-blind controlled trial initiated in 1944 has led to the common narrative that a 10-mg daily vitamin C intake is adequate to prevent and treat impaired wound healing, and by inference, other collagen-related diseases such as heart disease or stroke. The WHO relies on this narrative to set the recommended nutrient intake for vitamin C. This narrative, however, is based on what is known as the eyeball method of data assessment. The 1944 trial published individual participant data on scar strength providing an opportunity to ...
Source: The American Journal of Clinical Nutrition - August 16, 2021 Category: Nutrition Authors: Philippe P Hujoel Margaux L A Hujoel Source Type: research