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Total 1014 results found since Jan 2013.

Acute ischemic stroke in children & #8211; should we thrombolyze ?
KP Vinayan, Vivek Nambiar, Vaishakh AnandAnnals of Indian Academy of Neurology 2022 25(1):21-25 Ischemic stroke is a major cause of acute neurological symptoms in children with significant long-term neurological sequelae. Unlike in the adult population, the clinical presentation of strokes in children may not be stereotyped. Hence, many other differential diagnostic possibilities might have to be considered in the emergency setting. Due to this heterogeneous presentation and the resultant clinical dilemma in the early detection, acute thrombolysis even now remains as a very rarely tried therapeutic option in children. Man...
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: KP Vinayan Vivek Nambiar Vaishakh Anand Source Type: research

Utility of transcranial magnetic stimulation and diffusion tensor imaging for prediction of upper-limb motor recovery in acute ischemic stroke patients
Conclusion: The accuracy of UL motor recovery can be predicted through the clinical battery and their elements as well as TMS (MEP) and DTI (FA) parameters. Further, well-designed prospective studies are needed to confirm our findings.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Pradeep Kumar Manya Prasad Animesh Das Deepti Vibha Ajay Garg Vinay Goyal Achal K Srivastava Source Type: research

Impact of the COVID-19 pandemic on the frequency, clinical spectrum and outcomes of pediatric guillain-Barr & #233; syndrome in India: A multicentric ambispective cohort study
Conclusions: The COVID-19 pandemic led to a marked decline in pediatric GBS presenting to hospitals. Antecedent illnesses, clinical and electrophysiological profile of GBS remained largely unchanged from the pre-pandemic era.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Divyani Garg Rajinder K Dhamija Aditya Choudhary Ritu Shree Sujit Kumar Priyanka Samal Abhishek Pathak Pamidimukkala Vijaya Yareeda Sireesha Sruthi S Nair Sanjay Sharma Soaham Desai Human P Sinha Ayush Agarwal Ashish Upadhyay MV Padma Srivastava Rohit Bha Source Type: research

Patients with Neurological Illnesses and Their Experience During the Lockdown: A Teleinterview-based Study
Conclusion: The ongoing pandemic will continue to pose challenges to both physicians and patients. Patients in follow-up may need to be contacted regularly and counselled regarding the importance of maintaining drug compliance. Telemedicine can be used to strengthen the healthcare delivery to patients with non-COVID illnesses.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Pranjal Gupta Biswamohan Misra Pachipala Sudheer Rohit Bhatia Mamta B Singh MV P. Srivastava Manjari Tripathi Achal K Srivastava Kameshwar Prasad Deepti Vibha VY Vishnu Awadh K Pandit Rajesh K Singh Anu Gupta A Elavarasi Animesh Das MR Divya Bhargavi Rama Source Type: research

PON1 (Paraoxonase 1) Q192R gene polymorphism in ischemic stroke among North Indian population
Conclusion: PON1 Q192R gene polymorphism is not associated with an increased risk of acute ischemic stroke in the North Indian population. Further studies with a larger sample size are needed before PON1 Q192R gene polymorphism can be considered as a genetic risk factor for ischemic stroke.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Ankit Gupta Alvee Saluja Kallur Nava Saraswathy Longkumer Imnameren Suniti Yadav Rajinder K Dhamija Source Type: research

Epidemiology of young stroke in the ludhiana population-based stroke registry
Conclusion: Hypertension, diabetes mellitus, drug addiction, and tobacco intake were significantly associated with young stroke. Outcome was also better in younger people.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Monika Singla Gagandeep Singh Paramdeep Kaur Jeyaraj D Pandian Source Type: research

The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice Neuroscience
Blood–brain barrier (BBB) breakdown and inflammation occurring at the BBB have a key, mainly a deleterious role in the pathophysiology of ischemic stroke. Neddylation is a ubiquitylation-like pathway that is critical in various cellular functions by conjugating neuronal precursor cell-expressed developmentally down-regulated protein 8 (NEDD8) to target proteins. However, the...
Source: Proceedings of the National Academy of Sciences - January 31, 2022 Category: Science Authors: Huilin Yu, Haiyu Luo, Luping Chang, Shisheng Wang, Xue Geng, Lijing Kang, Yi Zhong, Yongliang Cao, Ranran Wang, Xing Yang, Yuanbo Zhu, Mei-Juan Shi, Yue Hu, Zhongwang Liu, Xuhui Yin, Yunwei Ran, Hao Yang, Wenying Fan, Bing-Qiao Zhao Tags: Neuroscience Biological Sciences Source Type: research

Cervical artery dissection: A common cause of stroke in young adults
Cervical artery dissection is a common cause of stroke in young adults and can lead to significant disability. Clinicians should be able to recognize the clinical presentation and diagnose this condition to prevent cerebral ischemia and its complications. Consider cervical artery dissection in a young adult with new-onset, unilateral head pain with or without neck pain with antecedent neck trauma, with or without neurologic deficits or risk factors for dissection. Early diagnosis can lead to better outcomes but the overall prognosis is good for young adults with cervical artery dissection.
Source: Journal of the American Academy of Physician Assistants - January 27, 2022 Category: Primary Care Tags: Review Article Source Type: research

New Guidance on Consent in Acute Ischemic Stroke New Guidance on Consent in Acute Ischemic Stroke
The American Academy of Neurology has issued a new position statement on"Consent Issues in the Management of Acute Ischemic Stroke," the first update in more than 20 years.Medscape Medical News
Source: Medscape Cardiology Headlines - January 19, 2022 Category: Cardiology Tags: Cardiology News Source Type: news

AAN Position Statement Addresses Consent Issues in Acute Stroke
WEDNESDAY, Jan. 19, 2022 -- Issues relating to consent for people who have experienced acute ischemic stroke are addressed in an American Academy of Neurology position statement published online Jan. 10 in Neurology. Justin A. Sattin, M.D., from...
Source: Drugs.com - Pharma News - January 19, 2022 Category: Pharmaceuticals Source Type: news

Exercise medicine and physical activity promotion: core curricula for US medical schools, residencies and sports medicine fellowships: developed by the American Medical Society for Sports Medicine and endorsed by the Canadian Academy of Sport and Exercise Medicine
Br J Sports Med. 2022 Jan 10:bjsports-2021-104819. doi: 10.1136/bjsports-2021-104819. Online ahead of print.ABSTRACTRegular physical activity provides a variety of health benefits and is proven to treat and prevent several non-communicable diseases. Specifically, physical activity enhances muscular and osseous strength, improves cardiorespiratory fitness, and reduces the risk of hypertension, coronary heart disease, stroke, type 2 diabetes, mental health disorders, cognitive decline and several cancers. Despite these well-known benefits, physical activity promotion in clinical practice is underused due to insufficient trai...
Source: British Journal of Sports Medicine - January 11, 2022 Category: Sports Medicine Authors: Irfan Asif Jane S Thornton Stephen Carek Christopher Miles Melissa Nayak Melissa Novak Mark Stovak Jason L Zaremski Jonathan Drezner Source Type: research

Postoperative Complications in Patients With Hereditary Hemochromatosis Undergoing Total Joint Arthroplasty: A Matched Cohort Analysis
This study addresses a paucity in the current literature concerning the complication profile in HH patients with destructive joint arthropathy undergoing joint arthroplasty surgery.PMID:34932508 | DOI:10.5435/JAAOS-D-21-00105
Source: The Journal of the American Academy of Orthopaedic Surgeons - December 21, 2021 Category: Orthopaedics Authors: Amil R Agarwal Kevin Y Wang Amy L Xu Matthew J Best Varun Puvanesarajah Umasuthan Srikumaran Gregory J Golladay Savya C Thakkar Source Type: research

Rescue strategies in anterior circulation stroke with failed mechanical thrombectomy & #8212;A retrospective observational study (RAFT)
Conclusions: Rescue stenting and/or angioplasty after failed MT is a safe and effective recanalization method for AIS in anterior circulation without increasing mortality or morbidity.
Source: Annals of Indian Academy of Neurology - December 17, 2021 Category: Neurology Authors: Amit Ashok Bhatti Niranjan P Mahajan Devashish Dhiren Vyas Mudasir Mushtaq Shah Vikram Huded Source Type: research

Neurological disorders seen during second wave of SARS-CoV-2 pandemic from two tertiary care centers in central and Southern Kerala
Conclusion: During the SARS-CoV-2 pandemic, CAND and PVND have been emerging. Association of some of these may be fortuitous; however it is worth mentioning as pathogenic mechanisms of COVID-19 affecting various organ systems still remain unclear. Moreover, this may be helpful in future studies designing management options.
Source: Annals of Indian Academy of Neurology - December 17, 2021 Category: Neurology Authors: Minu George Neena Baby Ameen Azad Aswathy Rajan Suresh Kumar Radhakrishnan Source Type: research

Recurrent posterior circulation stroke as an initial manifestation of atlantoaxial dislocation in a child
N Devavrat, Karthik K, J Shumyla, K Neeraja, M NetravathiAnnals of Indian Academy of Neurology 2021 24(6):965-967
Source: Annals of Indian Academy of Neurology - December 17, 2021 Category: Neurology Authors: N Devavrat Karthik K J Shumyla K Neeraja M Netravathi Source Type: research