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Total 106 results found since Jan 2013.

Academic-industry Collaborations in Translational Stroke Research
Abstract Academic-industry collaborations are an emerging format of translational stroke research. Next to classic contract research models, a multitude of collaboration models has been developed, some of which even allowing for multinational or intercontinental research programs. This development has recently been paralleled by first successful attempts to overcome the translational stroke research road block, such as the unprecedented success of novel endovascular approaches or the advent of the multicenter preclinical trial concept. While the first underlines the role of the industry as a major innovation drive...
Source: Translational Stroke Research - June 13, 2016 Category: Neurology Source Type: research

Targeting brain-spleen crosstalk after stroke: new insights into stroke pathology and treatment
Curr Neuropharmacol. 2021 Mar 15. doi: 10.2174/1570159X19666210316092225. Online ahead of print.ABSTRACTThe immune response following acute stroke has received great attention. The spleen is an important immune organ, and more and more studies have shown that brain-spleen crosstalk after stroke plays an important role in its development and prognosis. There are many mechanisms of spleen activation after stroke, including activation of the sympathetic nervous system, the production of chemokines, and antigen presentation in the damaged brain. The changes in the spleen after stroke are mainly reflected in morphology, changes...
Source: Current Neuropharmacology - March 17, 2021 Category: Drugs & Pharmacology Authors: Dong Han Hang Liu Yan Gao Juan Feng Source Type: research

Pot Use Linked To An Increased Risk Of Stroke And Heart Failure
Adults who use marijuana may have an increased risk of stroke and heart failure, according to a new study. The people in the study who used marijuana were 26 percent more likely to have had a stroke at some point in their lives than those who did not use marijuana, the researchers found. The people who used marijuana were also 10 percent more likely to have developed heart failure at some point in their lives, compared with people who did not use marijuana, the researchers found. The new findings suggest that, like many other medications, cannabis may have side effects, and that patients who use marijuana for medical reaso...
Source: Healthy Living - The Huffington Post - March 15, 2017 Category: Consumer Health News Source Type: news

Stroke Rehab Technology Aims To Speed Healing
Watching someone who has suffered a stroke try to perform everyday actions such as walking down the sidewalk or even bringing a cup to their lips can serve as a sobering reminder of how fragile full and robust health is, and also serves as an inspiration for those dedicated to improving the lives of those patients. Steven Plymale, recently named CEO of Toronto-based MyndTec, said his reaction to watching videos of patients using the company's MyndMove functional electrical stimulation (FES) rehabilitation system was one of the reasons he joined MyndTec. "They are very compelling," Plymale said of the demonstration videos,Â...
Source: MDDI - November 22, 2017 Category: Medical Devices Authors: Greg Goth Tags: Electronics Source Type: news

Unipolar stroke, electroosmotic pump carbon nanotube yarn muscles
Success in making artificial muscles that are faster and more powerful and that provide larger strokes would expand their applications. Electrochemical carbon nanotube yarn muscles are of special interest because of their relatively high energy conversion efficiencies. However, they are bipolar, meaning that they do not monotonically expand or contract over the available potential range. This limits muscle stroke and work capacity. Here, we describe unipolar stroke carbon nanotube yarn muscles in which muscle stroke changes between extreme potentials are additive and muscle stroke substantially increases with increasing po...
Source: ScienceNOW - January 28, 2021 Category: Science Authors: Chu, H., Hu, X., Wang, Z., Mu, J., Li, N., Zhou, X., Fang, S., Haines, C. S., Park, J. W., Qin, S., Yuan, N., Xu, J., Tawfick, S., Kim, H., Conlin, P., Cho, M., Cho, K., Oh, J., Nielsen, S., Alberto, K. A., Razal, J. M., Foroughi, J., Spinks, G. M., Kim, Tags: Materials Science reports Source Type: news

Can you learn to cough after having a stroke?
A strong cough, requires powerful coordinated contraction of expiratory (abdominal) muscles. The expiratory muscles contract to build up high positive intrapleural and intra-airway pressures for development of peak expiratory Flow rates. Expiratory muscle strength training (EMST) has been shown to improve parameters related to pulmonary function, speech, and cough.However, no one has investigated what changes occur in the activation of abdominal muscles after training. The aim of this study is to clarify which role plays the coordination of abdominal muscles in expiratory flows. The null hypothesis was that stroke patients...
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Dominguez Sanz, N. Tags: 09.02 - Physiotherapists Source Type: research

The Anticonvulsant Screening Program of the National Institute of Neurological Disorders and Stroke, NIH: History and Contributions to Clinical Care in the Twentieth Century and Beyond.
Abstract The anticonvulsant screening program (ASP) of the national institute of neurological disorders and stroke (NINDS), National Institutes of Health has made substantial contributions to the drug armamentarium of the clinical neurologist. This program, originally a part of the overall Drug Development Program of the Epilepsy Branch, has been fortunate to have talented leadership, both at NINDS in Maryland and at the major contract site, the University of Utah-over a remarkable period of more than 40 years. Future discoveries by the ASP (now renamed the Epilepsy Therapy Screening) can be expected to make addit...
Source: Neurochemical Research - March 8, 2017 Category: Neuroscience Authors: Porter RJ, Kupferberg HJ Tags: Neurochem Res Source Type: research

Alcids 'fly' at efficient Strouhal numbers in both air and water but vary stroke velocity and angle
Birds that use their wings for 'flight' in both air and water are expected to fly poorly in each fluid relative to single-fluid specialists; i.e., these jacks-of-all-trades should be the masters of none. Alcids exhibit exceptional dive performance while retaining aerial flight. We hypothesized that alcids maintain efficient Strouhal numbers and stroke velocities across air and water, allowing them to mitigate the costs of their 'fluid generalism'. We show that alcids cruise at Strouhal numbers between 0.10 and 0.40 – on par with single-fluid specialists – in both air and water but flap their wings ~50% slower in water....
Source: eLife - June 30, 2020 Category: Biomedical Science Tags: Ecology Evolutionary Biology Source Type: research

Alcids ‘fly’ at efficient Strouhal numbers in both air and water but vary stroke velocity and angle
Birds that use their wings for ‘flight’ in both air and water are expected to fly poorly in each fluid relative to single-fluid specialists; that is, these jacks-of-all-trades should be the masters of none. Alcids exhibit exceptional dive performance while retaining aerial flight. We hypothesized that alcids maintain efficien t Strouhal numbers and stroke velocities across air and water, allowing them to mitigate the costs of their ‘fluid generalism’. We show that alcids cruise at Strouhal numbers between 0.10 and 0.40 – on par with single-fluid specialists – in both air and water but flap their wings ~ 50% slo...
Source: eLife - June 30, 2020 Category: Biomedical Science Tags: Ecology Evolutionary Biology Source Type: research

Guided Self-rehabilitation Contract vs conventional therapy in chronic stroke-induced hemiparesis: NEURORESTORE, a multicenter randomized controlled trial
After discharge from hospital following a stroke, prescriptions of community-based rehabilitation are often downgraded to “maintenance†rehabilitation or discontinued. This classic therapeutic behavior stems f...
Source: BMC Neurology - March 12, 2019 Category: Neurology Authors: Jean-Michel Gracies, Maud Pradines, Mouna Gh édira, Catherine-Marie Loche, Valentina Mardale, Catherine Hennegrave, Caroline Gault-Colas, Etienne Audureau, Emilie Hutin, Marjolaine Baude and Nicolas Bayle Tags: Study protocol Source Type: research