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Source: Frontiers in Neurology
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Total 2557 results found since Jan 2013.
Neurological scoring and gait kinematics to assess functional outcome in an ovine model of ischaemic stroke
ConclusionThis study developed repeatable methods to assess function in sheep using composite scoring and gait kinematics, allowing for the evaluation of deficit 3 days post-stroke. Despite utility of each method independently, there was poor association observed between gait kinematics, composite scoring, and infarct volume on PCA. This suggests that each of these measures has discreet utility for the assessment of stroke deficit, and that multimodal approaches are necessary to comprehensively characterise functional impairment.
Source: Frontiers in Neurology - February 20, 2023 Category: Neurology Source Type: research
Twenty-four-hour ambulatory blood pressure variability and association with ischemic stroke subtypes in the subacute stage
ConclusionThe results of this study indicate a discrepancy in blood pressure variability among different ischemic stroke subtypes during the subacute stage. Higher systolic blood pressure and systolic blood pressure variability during the 24 h, daytime, and nighttime, and nighttime diastolic blood pressure were independent predictors for large-artery atherosclerosis stroke. Increased nighttime diastolic BPV was an independent risk factor for cardioembolic stroke.
Source: Frontiers in Neurology - April 17, 2023 Category: Neurology Source Type: research
Serum retinol-binding protein 4 in stroke patients: correlation with T helper 17/regulatory T cell imbalance and 3-year cognitive function decline
ConclusionSerum RBP4 is positively associated with a Th17/Treg cell imbalance and, more importantly, it is indicative of cognitive function decline within 3 years in stroke patients. Thus, early and timely interventions and physical rehabilitation are more necessary in stroke patients with high serum RBP4.
Source: Frontiers in Neurology - September 21, 2023 Category: Neurology Source Type: research
Assessment of Carotid Intraplaque Neovascularization Using Superb Microvascular Imaging in High Risk of Stroke Individuals: Results From a Community-Based Study
Conclusions: Moderate to marked intraplaque neovascularization detected by SMI was more likely in subjects with a history of any territory stroke or TIA or thicker plaque. This indicates a potential new role of SMI in stratifying future risk of stroke or other arterial disease complications.
Source: Frontiers in Neurology - November 6, 2019 Category: Neurology Source Type: research
Timing of Repetitive Transcranial Magnetic Stimulation Onset for Upper Limb Function After Stroke: A Systematic Review and Meta-Analysis
Conclusions: Based on the FMA, rTMS seems more beneficial only when started in the first month post-stroke. Tests at the level of function are likely more sensitive to detect beneficial rTMS effects on upper limb function than tests at the level of activity. However, heterogeneities in treatment designs and outcomes are high. Future rTMS trials should include the FMA and work toward a core set of outcome measures.
Source: Frontiers in Neurology - December 2, 2019 Category: Neurology Source Type: research
Interdisciplinary Stroke Recovery Research: The Perspective of Occupational Therapists in Acute Care
This article discusses the importance of the OTs' perspectives in conducting interdisciplinary, longitudinal stroke recovery research. The challenges, strategies and recommendations for future directions of advancing the role of OTs in multidisciplinary stroke recovery research are highlighted. We use this perspective as a call to action to the stroke recovery field to incorporate OTs as members of the research team and for OTs to provide their perspectives on ongoing stroke recovery research.
Source: Frontiers in Neurology - December 16, 2019 Category: Neurology Source Type: research
Association of LDL-C/HDL-C Ratio With Stroke Outcomes Within 1 Year After Onset: A Hospital-Based Follow-Up Study
Stroke remains a leading cause of death and disability. The low-density lipoprotein cholesterol to high-density lipoprotein cholesterol (LDL-C/HDL-C ratio) ratio has been confirmed to be a predictor of stroke. However, few studies have assessed the prognostic impact of the LDL-C/HDL-C ratio for stroke patients. We aimed to investigate the relationship between the LDL-C/HDL-C ratio and the prognosis following stroke in Chinese patients. A total of 3,410 patients who had experienced their first ischemic stroke was recruited to this study within 72 h of stroke onset. The patients were followed for at least 12 months. A multiv...
Source: Frontiers in Neurology - May 14, 2020 Category: Neurology Source Type: research
Acute Neurofilament Light Chain Plasma Levels Correlate With Stroke Severity and Clinical Outcome in Ischemic Stroke Patients
Conclusions: Plasma NF-L levels, but not IL-6 and S100B, were significant predictors of clinical severity on admission and functional outcome at 3 months. Plasma NF-L is a promising biomarker of functional outcome after ischemic stroke.
Source: Frontiers in Neurology - June 10, 2020 Category: Neurology Source Type: research
Serum Sphingosine 1-Phosphate (S1P): A Novel Diagnostic Biomarker in Early Acute Ischemic Stroke
Conclusions: The present study preliminarily investigated the diagnostic value of serum S1P in acute stroke. Decreased serum S1P may become a potential biomarker for early acute ischemic stroke and can indicate disease severity.
Source: Frontiers in Neurology - September 7, 2020 Category: Neurology Source Type: research
Oral Health, Oral Microbiota, and Incidence of Stroke-Associated Pneumonia —A Prospective Observational Study
This study involved three investigation timepoints. The baseline investigation (within 24 h of admission) involved collection of demographic, neurological, and immunological data; dental examinations; and microbiological sampling (saliva and subgingival plaque). Further investigation timepoints at 48 or 120 h after baseline included collection of immunological data and microbiological sampling. Microbiological samples were analyzed by culture technique and by 16S rRNA amplicon sequencing. From the 99 patients included in this study, 57 were diagnosed with stroke and 42 were so-called stroke mimics. From 57 stroke patients,...
Source: Frontiers in Neurology - November 6, 2020 Category: Neurology Source Type: research
Stroke-Induced Modulation of Myeloid-Derived Suppressor Cells (MDSCs) and IL-10-Producing Regulatory Monocytes
Conclusions: MDSC and IL-10+ monocytes can induce immunosuppression within days after stroke.
Source: Frontiers in Neurology - November 25, 2020 Category: Neurology Source Type: research
Rehabilitation and Biomarkers of Stroke Recovery: Study Protocol for a Randomized Controlled Trial
Discussion: This trial will deal with the effects of an intensive self-management rehabilitation protocol and a related set of biomarkers. It will also investigate the role of training intensity on long-term recovery after stroke. In addition, it will define a set of biomarkers related to post-stroke recovery and neurorehabilitation outcome in order to detect patients with greater potential and define long-term individualized rehabilitation programs.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT04323501.
Source: Frontiers in Neurology - January 15, 2021 Category: Neurology Source Type: research
Risk Factors of Hypoperfusion on MRI of Ischemic Stroke Patients Within 7 Days of Onset
Conclusion: Our results suggest that prior stroke and vascular stenosis (≥70%) are strong predictors of hypoperfusion in patients with acute ischemic stroke within 7 days of stroke onset.
Source: Frontiers in Neurology - May 7, 2021 Category: Neurology Source Type: research
High Neutrophil –Lymphocyte Ratio Predicts Post-stroke Cognitive Impairment in Acute Ischemic Stroke Patients
Conclusions: NLR in the acute stage of ischemic stroke was independently associated with PSCI at 3 months after stroke, and high NLR was specifically associated with cognitive dysfunction in the memory and visuospatial domains. Thus, systemic inflammation may be a modifiable risk factor that may influence cognitive outcomes after stroke.
Source: Frontiers in Neurology - July 1, 2021 Category: Neurology Source Type: research
Functional Disability After Ischemic Stroke: A Community-Based Cross-Sectional Study in Shanghai, China
Conclusion: Lower degrees of functional independence are related to cognitive impairment, as well as the previous stroke history and depression status.
Source: Frontiers in Neurology - August 26, 2021 Category: Neurology Source Type: research
