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Source: Frontiers in Neurology

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Total 2557 results found since Jan 2013.

Lasting impairments following transient ischemic attack and minor stroke: a systematic review protocol
IntroductionThe focus on medical management and secondary prevention following Transient Ischemic Attack (TIA) and minor stroke is well-established. Evidence is emerging that people with TIA and minor stroke can experience lasting impairments as fatigue, depression, anxiety, cognitive impairment, and communication difficulties. These impairments are often underrecognized and inconsistently treated. Research in this area is developing rapidly and an updated systematic review is required to evaluate new evidence as it emerges. This living systematic review aims to describe the prevalence of lasting impairments and how they a...
Source: Frontiers in Neurology - May 12, 2023 Category: Neurology Source Type: research

Strengthening stroke prevention and awareness in the Philippines: a conceptual framework
This article focuses on stroke prevention and awareness in the Philippines, a country grappling with high stroke incidence and limited healthcare resources. The two-pronged approach presented by the authors aims to address the challenges of stroke care by combining community-based prevention and targeted public awareness campaigns. The community-based stroke prevention component involves personalized risk factor assessments and tailored interventions conducted at local health centers. By identifying modifiable risk factors such as hypertension, diabetes, smoking, and elevated cholesterol levels, healthcare professionals ca...
Source: Frontiers in Neurology - August 31, 2023 Category: Neurology Source Type: research

Knowledge and awareness of stroke and associated factors in the Saudi general population: a cross-sectional study
ConclusionOur study revealed that participants have good knowledge about stroke. Nonetheless, further efforts are required to raise awareness and educate the public to optimize and ensure better treatment outcomes.
Source: Frontiers in Neurology - September 21, 2023 Category: Neurology Source Type: research

Body Mass Index and Prognosis in Ischemic Stroke Patients With Type 2 Diabetes Mellitus
This study showed the overall presence of the obesity paradox in stroke patients with T2DM. However, obese patients had different risks of cardiovascular events and stroke.
Source: Frontiers in Neurology - June 4, 2019 Category: Neurology Source Type: research

Cell-Based Therapies for Stroke: Are We There Yet?
Stroke is the second leading cause of death and physical disability, with a global lifetime incidence rate of 1 in 6. Currently, the only FDA approved treatment for ischemic stroke is the administration of tissue plasminogen activator (tPA). Stem cell clinical trials for stroke have been underway for close to two decades, with data suggesting that cell therapies are safe, feasible, and potentially efficacious. However, clinical trials for stroke account for less than 1% of all stem cell trials. Nevertheless, the resources devoted to clinical research to identify new treatments for stroke is still significant (53 to 64 mill...
Source: Frontiers in Neurology - June 24, 2019 Category: Neurology Source Type: research

Perturbation-Induced Stepping Post-stroke: A Pilot Study Demonstrating Altered Strategies of Both Legs
Conclusions. Stepping with the more-involved leg can be facilitated by unweighting the leg. The differences between groups, and legs in post-stroke participants illustrate the simultaneous bipedal role (support and stepping) both legs have in reactive stepping
Source: Frontiers in Neurology - July 2, 2019 Category: Neurology Source Type: research

CODE STROKE ALERT —Concept and Development of a Novel Open-Source Platform to Streamline Acute Stroke Management
Discussion Code Stroke Alert will be freely available to health networks globally. The open-source nature of the software offers valuable potential for future development of plug-ins and add-ons, based on individual institutional needs. Prospective, multi-site implementation and measurement of clinical impact are underway.
Source: Frontiers in Neurology - July 30, 2019 Category: Neurology Source Type: research

Inhibition of CD147 Attenuates Stroke-Associated Pneumonia Through Modulating Lung Immune Response in Mice
Conclusions—Inhibition of CD147 ameliorates aberrant lung inflammatory and immune response and reduces bacterial infection after stroke. CD147 might represent a novel and promising therapeutic target for post-stroke lung infection.
Source: Frontiers in Neurology - August 6, 2019 Category: Neurology Source Type: research

Severely Disturbed Sleep in Patients With Acute Ischemic Stroke on Stroke Units: A Pilot Study
Conclusion: We show that sleep is severely disturbed in patients with acute ischemic stroke admitted to stroke units. Larger studies are needed to clarify associations between deprivation of deep sleep and secondary deterioration.
Source: Frontiers in Neurology - October 24, 2019 Category: Neurology Source Type: research

Baseline Red Blood Cell Distribution Width as a Predictor of Stroke Occurrence and Outcome: A Comprehensive Meta-Analysis of 31 Studies
Conclusions: Baseline RDW should be integrated into clinical practice as a predictor of ischemic stroke occurrence and outcome. Future studies should also explore the dynamic change of RDW in post-stroke patients to evaluate the clinical significance of RDW and its impact on the inflammatory state of ischemic stroke.
Source: Frontiers in Neurology - November 25, 2019 Category: Neurology Source Type: research

Comparison of the Four Anthropometric Indexes and Their Association With Stroke: A Population-Based Cross-Sectional Study in Jilin Province, China
Conclusions: The waist-to-height ratio was more closely related to the prevalence of stroke than body mass index, waist circumference, and weight-to-hip ratio among the study participants aged ≥ 40 years.
Source: Frontiers in Neurology - December 9, 2019 Category: Neurology Source Type: research

Fast-Track Long Term Continuous Heart Monitoring in a Stroke Clinic: A Feasibility Study
Conclusion: It is feasible to implement a fast-track cardiac monitoring as part of a stroke clinic with proper training of stroke providers, clinic staff, and support from a cardiology team.
Source: Frontiers in Neurology - January 20, 2020 Category: Neurology Source Type: research

Risk Factors for Epilepsy After Thrombolysis for Ischemic Stroke: A Cohort Study
In this study, we examine risk factors and consequences of intravenous rt-PA for treatment of acute ischemic stroke. In a retrospective cohort study we evaluate risk factors for seizure and epilepsy after stroke thrombolysis, as well as the impact of seizures and epilepsy in outcome of stroke patients. In our cohort, mean age of patients was 67.2 years old (SD = 13.1) and 79 of them (51.6%) were male and. Initial NIHSS mean score were 10.95 (SD = 6.25). Three months NIHSS mean score was 2.09 (SD = 3.55). Eighty seven (56.9%) patients were mRS of 0–1 after thrombolysis. Hemorrhagic transformation was observed in 22 (14.4%...
Source: Frontiers in Neurology - January 22, 2020 Category: Neurology Source Type: research

Positive Influence of Stroke Health Manager on Risk Factors Control and Medication Adherence After Ischemic Stroke
Conclusions: Stroke health manager intervention improved the control of blood pressure, LDL-C, glucose levels and the persistence for secondary prevention medications 3 months after discharge.
Source: Frontiers in Neurology - March 10, 2020 Category: Neurology Source Type: research

Inflammatory Responses in the Secondary Thalamic Injury After Cortical Ischemic Stroke
Stroke is one of the major causes of chronic disability worldwide and increasing efforts have focused on studying brain repair and recovery after stroke. Following stroke, the primary injury site can disrupt functional connections in nearby and remotely connected brain regions, resulting in the development of secondary injuries that may impede long-term functional recovery. In particular, secondary degenerative injury occurs in the connected ipsilesional thalamus following a cortical stroke. Although secondary thalamic injury was first described decades ago, the underlying mechanisms still remain unclear. We performed a sy...
Source: Frontiers in Neurology - April 6, 2020 Category: Neurology Source Type: research