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Source: Frontiers in Neurology

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Total 2557 results found since Jan 2013.

Immune Alterations Following Neurological Disorders: A Comparison of Stroke and Seizures
Conclusion: Seizures lead to immune alterations within the immediate postictal period similar but not identical to stroke. The type of seizures determines the extent of immune alterations.
Source: Frontiers in Neurology - June 1, 2020 Category: Neurology Source Type: research

Prior Stroke in PFO Patients Is Associated With Both PFO-Related and -Unrelated Factors
Conclusion: In patients with CS and PFO, the likelihood of prior stroke is associated with both, PFO-related and PFO-unrelated factors.
Source: Frontiers in Neurology - June 3, 2020 Category: Neurology Source Type: research

Triglyceride Glucose Index and Prognosis of Patients With Ischemic Stroke
Conclusion: TyG index representing insulin resistance was associated with an increased risk of stroke recurrence, all-cause mortality, and neurologic worsening in patients with ischemic stroke.
Source: Frontiers in Neurology - June 9, 2020 Category: Neurology Source Type: research

Acquired Visual Deficits Independent of Lesion Site in Acute Stroke
Most clinical diagnoses of stroke are based on the persistence of symptoms relating to consciousness, language, visual-field loss, extraocular movement, neglect (visual), motor strength, and sensory loss following acute cerebral infarction. Yet despite the fact that most motor actions and cognition are driven by vision, functional vision per se is seldom tested rigorously during hospitalization. Hence we set out to determine the effects of acute stroke on functional vision, using an iPad application (Melbourne Rapid Field-Neural) that can be used to assess vision (visual acuity and visual field sensitivity) at the bedside ...
Source: Frontiers in Neurology - July 16, 2020 Category: Neurology Source Type: research

Impact of Jilin Province Stroke Emergency Maps on Acute Stroke Care Improvement in Northeast China
Conclusion: The JSEM, a regional stroke emergency network, serves to improve patient care for stroke. The map's publication increased rates of intravenous thrombolysis and mechanical thrombectomy. JSEM effectively connected more qualified designated hospitals, stroke patients and emergency medical service systems in Jilin province.
Source: Frontiers in Neurology - July 21, 2020 Category: Neurology Source Type: research

Predictors and Changes of Self-Perceived Burden Among Stroke Survivors: A 3-Month Follow-Up Study
Conclusions: Patients experienced a high degree of SPB in the early stage after stroke. Addressing the characteristics and predicting factors as well as the development of a targeted intervention for SPB may improve survival and post-stroke disability.
Source: Frontiers in Neurology - July 23, 2020 Category: Neurology Source Type: research

Acute Ischemic Stroke and COVID-19: Experience From a Comprehensive Stroke Center in Midwest US
Conclusion: AIS in the setting of COVID-19 is associated with worse outcomes, especially among African-American and Latino populations. Large vessel disease with ESUS was common suggesting an increased risk of coagulopathy and endothelial dysfunction as a potential etiology.
Source: Frontiers in Neurology - August 19, 2020 Category: Neurology Source Type: research

Comparison and Analysis of Epidemiologic Characteristics of Stroke in Sichuan Province, China
In conclusion, the disparity of lower stroke burden in Sichuan than the average China remained, although with the great developments in Sichuan province over all those decades. In addition to traditional modifiable factors, we suggest that unknown or intrinsic differences such as genetic factors might play an important role in geographic disparity, which should be investigated in future studies.
Source: Frontiers in Neurology - August 26, 2020 Category: Neurology Source Type: research

Consensus-Based Core Set of Outcome Measures for Clinical Motor Rehabilitation After Stroke —A Delphi Study
Conclusion: Agreement was found upon a set of nine outcome measures for application in clinical motor rehabilitation poststroke, with seven measurement time points following the stages of poststroke recovery. This core set was specifically developed for clinical practice and distinguishes itself from initiatives for stroke rehabilitation research. The next challenge is to implement this clinical core set across the full stroke care continuum with the aim to improve the transparency, comparability, and quality of stroke rehabilitation at a regional, national, and international level.
Source: Frontiers in Neurology - September 1, 2020 Category: Neurology Source Type: research

White Matter Hyperintensity Burden Is Associated With Hippocampal Subfield Volume in Stroke
White matter hyperintensities of presumed vascular origin (WMH) are a prevalent form of cerebral small-vessel disease and an important risk factor for post-stroke cognitive dysfunction. Despite this prevalence, it is not well understood how WMH contributes to post-stroke cognitive dysfunction. Preliminary findings suggest that increasing WMH volume is associated with total hippocampal volume in chronic stroke patients. The hippocampus, however, is a complex structure with distinct subfields that have varying roles in the function of the hippocampal circuitry and unique anatomical projections to different brain regions. For...
Source: Frontiers in Neurology - October 26, 2020 Category: Neurology Source Type: research

Impact of COVID-19 on Stroke Admissions and the Medical Care System in the Tokyo Metropolitan Area
Conclusion: The COVID-19 pandemic had a major impact on stroke care in Tokyo, including stroke admissions and medical care systems, resulting in a significant reduction in thrombolysis and thrombectomy. The extent of the drop may be the result of the number of COVID-19 patients.
Source: Frontiers in Neurology - November 30, 2020 Category: Neurology Source Type: research

Patterns of Infarction on MRI in Patients With Acute Ischemic Stroke and Cardio-Embolism: A Systematic Review and Meta-Analysis
Conclusion: The findings of this systematic review and meta-analysis are broadly consistent with previous literature and provide more robust evidence on the association between infarct topography, volume and stroke etiology. Our findings may assist with refining cardiac investigations for patients with cryptogenic stroke, based on infarct topography.
Source: Frontiers in Neurology - December 8, 2020 Category: Neurology Source Type: research

Decomposing Acute Symptom Severity in Large Vessel Occlusion Stroke: Association With Multiparametric CT Imaging and Clinical Parameters
Conclusions: We determined total ischemic volume, clot burden and age as relevant drivers for baseline NIHSS in acute LVO stroke. This suggests that not only mere volume but also degree of occlusion influences symptom severity. Use of imaging parameters as surrogate for baseline NIHSS reached limited performance underlining the need for combined clinical and imaging assessment in acute stroke management.
Source: Frontiers in Neurology - March 11, 2021 Category: Neurology Source Type: research

Exploring How Low Oxygen Post Conditioning Improves Stroke-Induced Cognitive Impairment: A Consideration of Amyloid-Beta Loading and Other Mechanisms
Cognitive impairment is a common and disruptive outcome for stroke survivors, which is recognized to be notoriously difficult to treat. Previously, we have shown that low oxygen post-conditioning (LOPC) improves motor function and limits secondary neuronal loss in the thalamus after experimental stroke. There is also emerging evidence that LOPC may improve cognitive function post-stroke. In the current study we aimed to explore how exposure to LOPC may improve cognition post-stroke. Experimental stroke was induced using photothrombotic occlusion in adult, male C57BL/6 mice. At 72 h post-stroke animals were randomly assigne...
Source: Frontiers in Neurology - March 24, 2021 Category: Neurology Source Type: research

Autotitrating Bilevel Positive Airway Pressure in Large Vessel Steno-Occlusive Stroke Patients With Suspected Sleep Apnea: A Multicenter Randomized Controlled Study
Conclusions: In this prematurely terminated trial, auto-BPAP was safe but did not show an effect on short-term clinical outcomes in selected ischemic stroke patients. Its tolerability, however, may be limited in hyperacute stroke care and needs to be improved before larger trials are conducted.Clinical Trial Registration:ClinicalTrials.gov, identifier: NCT01812993.
Source: Frontiers in Neurology - April 13, 2021 Category: Neurology Source Type: research