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Total 554 results found since Jan 2013.

A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
Conclusions concludes this work along with future work. Dataset and Data Preprocessing In the work, we mainly focus on multiple chronic disease classification. It can be formulated into a multi-label classification problem. There are three common chronic diseases are selected from the physical examination records: hypertension (H), diabetes (D), and fatty liver (FL). In the experiments, the physical examination datasets are collected from a local medical center, which contain 110,300 physical examination records from about 80,000 anonymous patients (Li et al., 2017a,b). Sixty-two feature items are selected from over 100...
Source: Frontiers in Genetics - April 23, 2019 Category: Genetics & Stem Cells Source Type: research

Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription. Introduction Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Predictors of Quality of Life among Older People with Mild Cognitive Impairment Attending Urban Primary Care Clinics.
CONCLUSIONS: MCI was prevalent among study participants and were associated with poorer QOL in all domains of QOL. A better understanding of predictors of QOL in older people with MCI is deemed important. CLINICAL IMPLICATION: Routine cognitive screening at primary care clinics will facilitate early recognition of MCI and facilitates referral to memory clinics for further assessment and treatment. PMID: 31107185 [PubMed - as supplied by publisher]
Source: Clinical Gerontologist - May 21, 2019 Category: Geriatrics Tags: Clin Gerontol Source Type: research

World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions
Publication date: Available online 2 September 2019Source: The Lancet Global HealthAuthor(s): Stephen Kaptoge, Lisa Pennells, Dirk De Bacquer, Marie Therese Cooney, Maryam Kavousi, Gretchen Stevens, Leanne Margaret Riley, Stefan Savin, Taskeen Khan, Servet Altay, Philippe Amouyel, Gerd Assmann, Steven Bell, Yoav Ben-Shlomo, Lisa Berkman, Joline W Beulens, Cecilia Björkelund, Michael Blaha, Dan G Blazer, Thomas BoltonSummaryBackgroundTo help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort to develop, evaluate, and illustrate revised risk models. ...
Source: The Lancet Global Health - September 4, 2019 Category: International Medicine & Public Health Source Type: research

Registration of amiloride in South Africa: Cutting the Gordian knot.
Authors: Rayner BL, Spence JD, Bryer A, Mpe MT Abstract Amiloride is an antagonist of the renal tubular epithelial sodium channel (ENaC). As such, it is a diuretic that is both potassium and magnesium sparing. It is used for the treatment of potassium depletion and hypertension, and is the specific therapy for hypertension due to overactivity of the ENaC (Liddle syndrome and several additional genetic causes of the Liddle phenotype - low renin and low aldosterone). It is listed as a World Health Organization essential drug, but has never been registered in South Africa (SA) and can therefore only be prescribed unde...
Source: South African Medical Journal - October 24, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Evaluation of the recovery outcome of poststroke cognitive impairment after cluster needling of scalp acupuncture therapy based on functional near ‐infrared spectroscopy
ConclusionsOur results suggest that cluster needling of scalp acupuncture is an effective treatment against PSCI and shed light on its application on other neurological disorders.
Source: Brain and Behavior - July 7, 2020 Category: Neurology Authors: Jing Chen, Hui Li, Chao Zeng, Jingge Li, Bin Zhao Tags: ORIGINAL RESEARCH Source Type: research

The Functionality, Evidence, and Privacy Issues Around Smartphone Apps for the Top Neuropsychiatric Conditions.
CONCLUSIONS: Most apps on the market targeted migraine, depression, and anxiety and contained interventions, although most of the interventions did not appear to be evidence based. Additionally, although most apps had privacy policies, lay people may have difficulty understanding these policies due to their complexities. PMID: 32669020 [PubMed - as supplied by publisher]
Source: Journal of Neuropsychiatry and Clinical Neurosciences - July 17, 2020 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Long-term exposure to PM and all-cause and cause-specific mortality: A systematic review and meta-analysis.
The objective of this review is to support the derivation of updated guidelines by the World Health Organization (WHO) by performing a systematic review of evidence of associations between long-term exposure to particulate matter with diameter under 2.5 µm (PM2.5) and particulate matter with diameter under 10 µm (PM10), in relation to all-cause and cause-specific mortality. As there is especially uncertainty about the relationship at the low and high end of the exposure range, the review needed to provide an indication of the shape of the concentration-response function (CRF). We systematically searched MEDLINE and EMB...
Source: Environment International - July 19, 2020 Category: Environmental Health Authors: Chen J, Hoek G Tags: Environ Int Source Type: research

High BMI: an important health risk factor among older adults in Ghana.
CONCLUSION: Prevalence of obesity and overweight in Ghana is high and increasing, which poses a health risk at the individual and population levels. Inter-sectorial and multidisciplinary measures in line with the national non-communicable disease policies aimed at curbing this trend are imperative. PMID: 33054895 [PubMed - as supplied by publisher]
Source: Public Health Nutrition - October 15, 2020 Category: International Medicine & Public Health Authors: Yorke E, Tetteh J, Boima V, Yawson AE Tags: Public Health Nutr Source Type: research

Interventions to increase patient and family involvement in escalation of care for acute life-threatening illness in community health and hospital settings.
CONCLUSIONS: Our review identified that interactional patient-facing interventions and multi-component programmes (including staff) to increase patient and family involvement in escalation of care for acute life-threatening illness may improve patient and family knowledge about danger signs and care-seeking responses, and probably have few adverse effects on patient's anxiety levels when compared to usual care. Multi-component interventions probably have little impact on mortality rates. Further high-quality trials are required using multi-component interventions and a focus on relational elements of care. Cognitive and be...
Source: Cochrane Database of Systematic Reviews - December 8, 2020 Category: General Medicine Authors: Mackintosh NJ, Davis RE, Easter A, Rayment-Jones H, Sevdalis N, Wilson S, Adams M, Sandall J Tags: Cochrane Database Syst Rev Source Type: research

Thrombolytic therapy for pulmonary embolism
CONCLUSIONS: Low-certainty evidence suggests that thrombolytics may reduce death following acute pulmonary embolism compared with heparin (the effectiveness was mainly driven by one trial with massive PE). Thrombolytic therapy may be helpful in reducing the recurrence of pulmonary emboli but may cause more major and minor haemorrhagic events, including haemorrhagic stroke. More studies of high methodological quality are needed to assess safety and cost effectiveness of thrombolytic therapy for people with pulmonary embolism.PMID:33857326 | DOI:10.1002/14651858.CD004437.pub6
Source: Cochrane Database of Systematic Reviews - April 15, 2021 Category: General Medicine Authors: Zhiliang Zuo Jirong Yue Bi Rong Dong Taixiang Wu Guan J Liu Qiukui Hao Source Type: research

Endovascular versus open surgical repair for complicated chronic Type B aortic dissection
CONCLUSIONS: Due to lack of RCTs or CCTs investigating the effectiveness and safety of TEVAR compared to OSR for patients with complicated CBAD, we are unable to provide any evidence to inform decision-making on the optimal intervention for these patients. High-quality RCTs or CCTs addressing this objective are necessary. However, conducting such studies will be challenging for this life-threatening disease.PMID:34905228 | DOI:10.1002/14651858.CD012992.pub2
Source: Cochrane Database of Systematic Reviews - December 14, 2021 Category: General Medicine Authors: Fionnuala Jordan Brian FitzGibbon Edel P Kavanagh Peter McHugh Dave Veerasingam Sherif Sultan Niamh Hynes Source Type: research

Poststroke Anxiety at 1 Year After Rehabilitation: A Multicenter Study
This study aimed to investigate the prevalence of and factors associated with anxiety among patients with stroke at the 1 year after rehabilitation from 9 tertiary centers. Anxiety, functional score, and quality of life were evaluated by the Hospital Anxiety and Depression Scale-anxiety subscale (HADS-A), modified Barthel Index, and World Health Organization Quality of Life-BREF (WHOQoL-BREF), respectively. This study reveals 20 (11.7%) patients with stroke who developed anxiety, and 18 from 171 patients (10.5%) were new cases of anxiety, which was more than double the rate at discharge (4.7%). Factors related to anxiety w...
Source: Topics in Geriatric Rehabilitation - January 1, 2022 Category: Geriatrics Tags: Thieves' Market Source Type: research

Burden of diseases attributed to traffic noise in the metropolis of Tehran in 2017
Environ Pollut. 2022 Feb 21:119042. doi: 10.1016/j.envpol.2022.119042. Online ahead of print.ABSTRACTAlthough road traffic noise is the most important source of environmental noise emission in large cities, little is known about health burden. The present study was conducted to estimate the burden of diseases attributed to traffic noise in the metropolis of Tehran in 2017. Using noise maps provided by the municipality of Tehran, we calculated population exposure distribution in term of Ldn and Lnight and the number of DALYs lost due to ischemic heart disease, hypertension, high sleep disturbance, annoyance and stroke endpo...
Source: Environmental Pollution - February 24, 2022 Category: Environmental Health Authors: Mansour Shamsipour Narges Zaredar Mohammad Reza Monazzam Zahra Namvar Saman Mohammadpour Source Type: research