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Flu jab may reduce severe effects of Covid, suggests study
Analysis of 75,000 coronavirus patients found fewer major health problems among people with flu jabCoronavirus – latest updatesSee all our coronavirus coveragePeople who are vaccinated against influenza may be partly protected against some of the severe effects of coronavirus, and be less likely to need emergency care, according to a major study.The analysis of nearly 75,000 Covid patients found significant reductions in stroke, deep vein thrombosis (DVT) and sepsis, and fewer admissions to emergency departments and intensive care units, among those who had been given the flu jab.Continue reading...
Source: Guardian Unlimited Science - July 12, 2021 Category: Science Authors: Ian Sample Science editor Tags: Medical research Coronavirus Vaccines and immunisation Health UK news Source Type: news

N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks)
CONCLUSION: The use of N-acetylcysteine should be considered in a number of conditions as our population ages and levels of glutathione drop. Supplementation may contribute to reducing morbidity and mortality in some chronic conditions as outlined in the article.PMID:34221501 | PMC:PMC8211525 | DOI:10.1155/2021/9949453
Source: Journal of Nutrition and Metabolism - July 5, 2021 Category: Nutrition Authors: Gerry K Schwalfenberg Source Type: research

Modulating Neurological Complications of Emerging Infectious Diseases: Mechanistic Approaches to Candidate Phytochemicals
Growing studies are revealing the critical manifestations of influenza, dengue virus (DENV) infection, Zika virus (ZIKV) disease, and Ebola virus disease (EVD) as emerging infectious diseases. However, their corresponding mechanisms of major complications headed for neuronal dysfunction are not entirely understood. From the mechanistic point of view, inflammatory/oxidative mediators are activated during emerging infectious diseases towards less cell migration, neurogenesis impairment, and neuronal death. Accordingly, the virus life cycle and associated enzymes, as well as host receptors, cytokine storm, and multiple signal...
Source: Frontiers in Pharmacology - October 26, 2021 Category: Drugs & Pharmacology Source Type: research

Ictogenesis of viral pneumonia: A comparison between SARS-CoV-2 and H1N1/H3N2
Epilepsy Behav. 2021 Dec 10;126:108470. doi: 10.1016/j.yebeh.2021.108470. Online ahead of print.ABSTRACTSeveral studies reported acute symptomatic seizures as a possible neurological complication of COVID-19 pneumonia. Apart from metabolic imbalances, hypoxia, and fever, other ictogenic mechanisms are likely related to an immune-mediated damage. The same mechanisms are shared by other respiratory viruses. Since neurotropic properties of SARS-CoV-2 have been questioned, we investigated whether SARS-CoV-2 has a similar ictogenic potential to other respiratory non-neurotropic viruses. We conducted a retrospective study identi...
Source: Epilepsy and Behaviour - December 13, 2021 Category: Neurology Authors: Chiara Milano Francesco Turco Chiara Pizzanelli Alessia Pascazio Enrico Tagliaferri Lorenzo Nesti Mauro Pistello Anna Lisa Capria Francesco Menichetti Francesco Forfori Enrica Bonanni Gabriele Siciliano Source Type: research

Influenza vaccination in patients with heart failure: A protocol for meta-analysis of randomized controlled trials
Discussion: This meta-analysis will evaluate the efficacy and safety of influenza vaccination in heart failure patients, providing evidence to the use of influenza vaccine in these patients. Systematic review registration: INPLASY202210115.
Source: Medicine - February 11, 2022 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Thrombotic events following Covid-19 vaccines compared to Influenza vaccines
CONCLUSIONS AND RELEVANCE: This study shows a significant increase in thrombotic events in subjects vaccinated with Covid-19 vaccines in comparison to a control group. The clinical implication of these findings should be interpreted with caution, in light of the high effectiveness of vaccination and the inherent risk of thrombosis from Covid-19 infection itself.PMID:35288031 | DOI:10.1016/j.ejim.2022.03.002
Source: European Journal of Internal Medicine - March 15, 2022 Category: Internal Medicine Authors: Marcelo Gabriel Vallone Andre Luis Falc ón Horacio Matias Castro Augusto Ferraris Ramiro Francisco Cantarella Mar ía Inés Staneloni Valeria Ines Aliperti Analia Ferloni Daniela Mezzarobba Fernando Javier V ázquez Mar ía Florencia Grande Ratti Source Type: research

Arterial Thrombotic Events in Hospitalized COVID-19 Patients: A Short Review and Meta-Analysis
In conclusion, we found a non-negligible proportion of ATE in patients hospitalized for COVID-19. Our results are similar to those found in hospitalized patients with influenza or with non-COVID viral pneumonia. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Thrombosis and Hemostasis - July 6, 2022 Category: Hematology Authors: Candeloro, Matteo Schulman, Sam Tags: Review Article Source Type: research

High-dose influenza vaccines for the prevention of hospitalization due to cardiovascular events in older adults in the nursing home: Post-hoc analysis of a cluster-randomized trial
Vaccine. 2022 Oct 13:S0264-410X(22)01215-4. doi: 10.1016/j.vaccine.2022.09.085. Online ahead of print.ABSTRACTOlder adults are at high risk of major acute cardiovascular events (MACE) linked to influenza illness andpreventable by influenza vaccination. It is unknown whether high-dose vaccine might incrementally reduce the risk of MACE.We conducted a post-hoc analysis of data collected from a pragmatic cluster randomized study of 823 nursing homes (NH) randomized to standard-dose (SD) or high-dose (HD) influenza vaccine in the 2013-14 season. Adults age 65 year or older who are Medicare-enrolled long-stay residents were inc...
Source: Vaccine - October 16, 2022 Category: Allergy & Immunology Authors: Elie A Saade Yasin Abul Kevin McConeghy H Edward Davidson Lisa Han Nina Joyce David H Canaday Leon Hsueh Elliott Bosco Stefan Gravenstein Source Type: research

Cold Weather Can Be Dangerous for the Human Body. This Winter Worries Experts
A particularly nasty trifecta of influenza, COVID-19, and respiratory syncytial virus (RSV) is already portending a rough winter. But there’s another factor contributing to a potentially tough season for health: a colder-than-average season, which is forecast in the northern U.S. and the U.K. Even an ordinary cold season can pose a threat to human health and safety. One 2015 study published in the Lancet analyzed over 74 million deaths around the world found that more than 7% of deaths were attributed to exposure to cold temperatures. “There is conclusive evidence that there is increased risk for many health ou...
Source: TIME: Health - November 15, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized healthscienceclimate Public Health Wellbeing Source Type: news

COVID-19 vs Influenza for Risk of Thrombotic Events in Hospitalized Patients —Reply
In Reply We appreciate the interest in our recent study and the opportunity to share our responses to the comments by Dr Yii and colleagues. We sought to assess whether the risk of arterial and venous thromboembolism among patients hospitalized with COVID-19 differed from those hospitalized with another respiratory viral infection. Patients with influenza in 2018-2019 were selected as the comparator because this pathogen also causes pandemics, results in hospitalization when severe, and is associated with increased risk of acute myocardial infarction, ischemic stroke, and venous thromboembolism. Evaluating outcomes of COVI...
Source: JAMA - December 27, 2022 Category: General Medicine Source Type: research