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Total 703 results found since Jan 2013.

Assessing Fluid Responsiveness in Spontaneously Breathing Patients.
CONCLUSIONS: Noninvasive assessment of fluid responsiveness in healthy volunteers and prediction of this response with a PLR maneuver is achievable. Further work is indicated to test these methods in acutely ill patients. PMID: 26764894 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - January 14, 2016 Category: Emergency Medicine Authors: Miller J, Ho CX, Tang J, Thompson R, Goldberg J, Amer A, Nahab B Tags: Acad Emerg Med Source Type: research

Smoking bans linked to fewer heart attacks and strokes
ConclusionThere is no doubt that tobacco smoking harms health and causes a great deal of disease and death. The World Health Organization (WHO) estimates that tobacco is responsible for one in 10 adult deaths worldwide.The question is whether smoking bans can help reduce the harm caused by tobacco. This summary of research suggests they can, particularly for people who are non-smokers. While it's hard to get good-quality evidence about the effects of smoking bans, comparisons of data from hospitals and national registries before and after a ban is helpful. However, we can't be sure the effects being measured are solely dow...
Source: NHS News Feed - February 4, 2016 Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Source Type: news

Preterm delivery and elevated maternal total vascular resistances (a prelude to the future maternal cardiovascular risk?)
ConclusionsWomen with diagnosis of TPD showing TVR values >1000 dynes.sec.cm−5 and elevated CRP levels are at high risk of preterm delivery. An impaired maternal cardiovascular adaptation during pregnancy in these patients might suggest a possible higher risk for subsequent future cardiovascular disease.
Source: Ultrasound in Obstetrics and Gynecology - March 1, 2016 Category: Radiology Authors: Herbert Valensise, Daniele Farsetti, Damiano Lo Presti, Ilaria Pisani, Grazia Maria Tiralongo, Giulia Gagliardi, Barbara Vasapollo, Gian Paolo Novelli Tags: Original Paper Source Type: research

Preterm delivery and elevated maternal total vascular resistances (a prelude to the future maternal cardiovascular risk?).
CONCLUSIONS: Women with diagnosis of TPD showing TVR values >1000 dynes.sec.cm(-5) and elevated CRP levels are at high risk of preterm delivery. An impaired maternal cardiovascular adaptation during pregnancy in these patients might suggest a possible higher risk for subsequent future cardiovascular disease. PMID: 26952308 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - March 8, 2016 Category: Radiology Authors: Valensise H, Farsetti D, Lo Presti D, Pisani I, Tiralongo GM, Gagliardi G, Vasapollo B, Novelli GP Tags: Ultrasound Obstet Gynecol Source Type: research

EPMA-World Congress 2015
Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of ...
Source: EPMA Journal - May 8, 2016 Category: Global & Universal Source Type: research

Impaired Maternal Hemodynamics in Morbidly Obese Women: A Case –control Study
ConclusionThe findings of our study suggest that cardiac function is significantly altered in morbidly obese pregnant women. In order to make appropriate comparisons between individuals, it is imperative that hemodynamic parameters are indexed for BSA – as indeed they are in pediatric cardiology. The novel finding of a reduced CI in morbidly obese pregnant women may explain the predisposition to preeclampsia and other adverse outcomes in this population and warrants further investigation.
Source: Ultrasound in Obstetrics and Gynecology - February 1, 2017 Category: Radiology Authors: D. Vinayagam, J Gutierrez, J Binder, E Mantovani, B. Thilaganathan, A. Khalil Tags: Original Paper Source Type: research

Impaired Maternal Hemodynamics in Morbidly Obese Women: A Case-control Study.
CONCLUSION: The findings of our study suggest that cardiac function is significantly altered in morbidly obese pregnant women. In order to make appropriate comparisons between individuals, it is imperative that hemodynamic parameters are indexed for BSA - as indeed they are in pediatric cardiology. The novel finding of a reduced CI in morbidly obese pregnant women may explain the predisposition to preeclampsia and other adverse outcomes in this population and warrants further investigation. PMID: 28150433 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - February 1, 2017 Category: Radiology Authors: Vinayagam D, Gutierrez J, Binder J, Mantovani E, Thilaganathan B, Khalil A Tags: Ultrasound Obstet Gynecol Source Type: research

Does coffee make you live longer?
Conclusion This study, conducted on a large number of people across Europe, was backed up by similar findings in the US. It appears to show some association between people who drink higher amounts of coffee and a reduced risk of death. But the "potentially beneficial clinical implications" need to be considered carefully for a number of reasons: Although the analyses were adjusted for some confounding variables, there may be a number of other factors that differ between the groups that account for the differences in death, such as socioeconomic status, family history, other medical conditions, and use of medic...
Source: NHS News Feed - July 12, 2017 Category: Consumer Health News Tags: Food/diet Source Type: news

Maternal hemodynamics, fetal biometry and Dopplers in pregnancies followed up for suspected fetal growth restriction.
CONCLUSIONS: In pregnancies with SGA fetuses there is decreased maternal cardiac output and stroke volume and increased peripheral vascular resistance and MAP and the deviations from normal are most marked in cases of redistribution in the fetal circulation and reduced amniotic fluid volume. PMID: 29607557 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - April 1, 2018 Category: Radiology Authors: Roberts LA, Ling HZ, Poon L, Nicolaides KH, Kametas NA Tags: Ultrasound Obstet Gynecol Source Type: research

Cardiac Structure and Function in Morbidly Obese Parturients: An Echocardiographic Study.
CONCLUSIONS: Cardiac index did not differ between obese pregnant women and those with normal BMI. Their increased left ventricular mass and lower stroke volume index could indicate a limited adaptive reserve. Obese women had minor decreases in septal left ventricular tissue Doppler velocity, but the E/E' average values did not suggest clinically significant diastolic dysfunction. PMID: 29878938 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - June 5, 2018 Category: Anesthesiology Authors: Buddeberg BS, Fernandes NL, Vorster A, Cupido BJ, Lombard CJ, Swanevelder JL, Girard T, Dyer RA Tags: Anesth Analg Source Type: research

Transfusion Therapy in a Multi-Ethnic Sickle Cell Population Real-World Practice. a Preliminary Data Analysis of Multicentre Survey
Conclusion. The transfusional approach is similar in HbSS, b°-thal/HbS and b+-thal/HbS patients with similar indications, prevalently VOCs and anemia. The significant higher age in Caucasian cohort and the consequent long term follow up could be the cause of variable therapeutic approach observed, however Hydroxycarbamide seemed to be the therapy more frequently used and finally suggested to manage chronic manifestations.Figure.DisclosuresOriga: Apopharma: Honoraria; Novartis: Honoraria; Bluebird Bio: Consultancy; Cerus Corporation: Research Funding. Forni: Apopharma: Other: DSM Board; Celgene: Research Funding; Novart...
Source: Blood - November 21, 2018 Category: Hematology Authors: Graziadei, G., Sainati, L., Bonomo, P., Venturelli, D., Masera, N., Casale, M., Vassanelli, A., Lodi, G., Piel, F. B., Voi, V., De Franceschi, L., Rigano, P., Quota, A., Notarangelo, L. D., Russo, G., Rosso, R., Allo, M., D'Ascola, D., Facchini, E., Macch Tags: 114. Hemoglobinopathies, Excluding Thalassemia-Clinical: Poster II Source Type: research

Blood Cell-Bound C4d as a Marker of Complement Activation in Patients With the Antiphospholipid Syndrome
In conclusion the detection of complement activation products on circulating erythrocytes and platelets using a highly sensitive and specific assay further supports the view that APS is a complement-mediated disorder. Increased EC4d and PC4d percentages are associated with the active inflammatory disease in SLE. It is difficult to translate this finding to APS which is a non-acute inflammatory disorder. We failed to find an association with both the classification and non-classification criteria, including thrombocytopenia. However, we believe that this sensitive tool to evaluate complement activation may offer more inform...
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research

Measurement of hemodynamics immediately after vaginal delivery in healthy pregnant women by electrical cardiometry.
Authors: Yoshida A, Kaji T, Yamada H, Yonetani N, Sogawa E, Yamao M, Maeda K, Sata M, Irahara M Abstract Few reports have focused on hemodynamics around delivery in pregnant women because of the difficulty of continuous and noninvasive measurement. Electrical cardiometry allows noninvasive continuous monitoring of hemodynamics and has recently been used in non-pregnant subjects. We compared the use of electrical cardiometry versus transthoracic echocardiography in healthy pregnant women and evaluated hemodynamics immediately after vaginal delivery. In Study 1, electrical cardiometry and transthoracic echocardiograp...
Source: Journal of Medical Investigation - May 10, 2019 Category: General Medicine Tags: J Med Invest Source Type: research

Impact of Male Origin Microchimerism on Cardiovascular Disease in Women: A Prospective Cohort Study.
Abstract Increasing parity is associated with an increased risk of ischemic heart disease (IHD) and stroke in women. This is likely attributed to biological responses of pregnancy. Male cells of presumed fetal origin are commonly present in women years after pregnancy-a phenomenon termed male origin microchimerism. Here, we investigated whether male origin microchimerism was associated with risk of IHD and ischemic stroke in women. We evaluated the association between male origin microchimerism and ischemic events in a cohort of 766 Danish women enrolled in the Diet, Cancer and Health cohort during 1993-1997 when ...
Source: Am J Epidemiol - November 13, 2020 Category: Epidemiology Authors: Hallum S, Gerds TA, Sehested TSG, Jakobsen MA, Tjønneland A, Kamper-Jørgensen M Tags: Am J Epidemiol Source Type: research

Impact of Male-Origin Microchimerism on Cardiovascular Disease in Women: A Prospective Cohort Study
In this study, we investigated whether MOM was associated with risk of IHD and ischemic stroke in women. We evaluated the association between MOM and ischemic events in a cohort of 766 Danish women enrolled in the Diet, Cancer and Health cohor t during 1993–1997 when aged 50–64 years. Of these women, 545 (71.2%) tested positive for MOM through targeting of the Y chromosome (DYS14 DNA sequence) in their blood. Multiple Cox regression models were used to calculate hazard ratios with 95% confidence intervals. We found that MOM was associated with a significantly reduced rate of IHD (hazard ratio  = 0.44, 95% confidence ...
Source: American Journal of Epidemiology - November 13, 2020 Category: Epidemiology Source Type: research