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Total 411 results found since Jan 2013.

PET/MRI Assessment of Acute Cardiac Inflammation 1 Month After Left-Sided Breast Cancer Radiation Therapy
Conclusion: Myocardial 18F-FDG uptake and functional MRI, including stroke volume and ECVs, were sensitive to changes at 1 mo after breast cancer RT, with findings suggesting an acute cardiac inflammatory response to RT.PMID:37192822 | DOI:10.2967/jnmt.122.264960
Source: Journal of Nuclear Medicine Technology - May 16, 2023 Category: Nuclear Medicine Authors: Oi Wai Chau Ali Islam Michael Lock Edward Yu Robert Dinniwell Brian Yaremko Muriel Brackstone William Pavlosky John Butler Heather Biernaski Chantelle Graf Gerald Wisenberg Frank S Prato Stewart Gaede Source Type: research

Assessment of thrombectomy procedure difficulty by neurointerventionalists based on vessel geometry parameters from carotid artery 3D reconstructions
CONCLUSIONS: Examining the vessel metrics and providing detailed vascular data tailored to patient characteristics may result in better procedure preparation, facilitate faster vessel access time, and improve thrombectomy outcomes. Additionally, documenting these correlations can enhance device design to ensure they suitably function under various vessel conditions.PMID:37262981 | DOI:10.1016/j.jocn.2023.05.014
Source: Clinical Breast Cancer - June 1, 2023 Category: Cancer & Oncology Authors: Mohammed Salman Shazeeb Viraj Moholkar Robert M King Srinivasan Vedantham Zeynep Vardar Afif Kraitem Clifford Lindsay Vania Anagnostakou Jasmeet Singh Francesco Massari Katyucia de Macedo Rodrigues Varun Naragum Ajit S Puri Sarena Carniato Matthew J Gouni Source Type: research

Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies
Adv Nutr. 2023 Jun 14:S2161-8313(23)01328-5. doi: 10.1016/j.advnut.2023.06.007. Online ahead of print.ABSTRACTThis umbrella review aims to provide a systematic and comprehensive overview of current evidence from prospective studies on the diverse health effects of cheese consumption. We searched PubMed, Embase, and Cochrane Library to identify meta-analyses/pooled analyses of prospective studies examining the associations between cheese consumption and major health outcomes from inception to August 31, 2022. We reanalyzed and updated previous meta-analyses and performed de novo meta-analyses with recently published prospec...
Source: Adv Data - June 16, 2023 Category: Epidemiology Authors: Mingjie Zhang Xiaocong Dong Zihui Huang Xue Li Yue Zhao Yingyao Wang Huilian Zhu Aiping Fang Edward L Giovannucci Source Type: research

Why is greater medication adherence associated with better outcomes
Background: To evaluate potential explanations for the association of greater adherence to placebo medication with better outcomes. Methods: The three explanations evaluated were that subjects with greater placebo adherence were 1) more likely to adhere to other medications, 2) had better healthcare behaviors, and 3) had lower risk. The data included more than 800 risk factors from the Women's Health Initiative (WHI), a nationwide study that included women who participated in randomized controlled trials of estrogen plus progestin (n=16,608) or estrogen alone (n=10,739). The median follow-up was 8 years. Linear regression ...
Source: Emerging Themes in Epidemiology - February 2, 2013 Category: Epidemiology Authors: Arthur HartzTao He Source Type: research

Could Antibodies or Hormones Slow Brain Damage from Alzheimer’s?
Scientists have discovered that certain antibodies may help slow the progression of Alzheimer’s disease. Dr. Patricia Salinas of University College London, UK, and her team focused on a protein called Dkk1, present in raised levels in the brains of people with Alzheimer’s disease. Using brain samples from mice, the team looked at the progressive disintegration of synapses in the hippocampus when exposed to a protein called amyloid-beta, thought to be central to the development of Alzheimer’s disease. “Synaptic loss mediated by amyloid-beta in early stages of the disease might contribute to cognitive...
Source: Psych Central - June 1, 2013 Category: Psychiatry Authors: Jane Collingwood Tags: Aging Alzheimer's Disorders General Seniors Abnormal Deposits Alzheimer S Disease Antibodies Brain Area Brain Damage Cognitive Decline Cognitive Impairments Disintegration Dr Patricia Dr Simon Hippocampus Journal Of Neurosc Source Type: news

Biomedical applications of sodium MRI in vivo
In this article we present an up‐to‐date overview of the potential biomedical applications of sodium magnetic resonance imaging (MRI) in vivo. Sodium MRI is a subject of increasing interest in translational imaging research as it can give some direct and quantitative biochemical information on the tissue viability, cell integrity and function, and therefore not only help the diagnosis but also the prognosis of diseases and treatment outcomes. It has already been applied in vivo in most human tissues, such as brain for stroke or tumor detection and therapeutic response, in breast cancer, in articular cartilage, in muscl...
Source: Journal of Magnetic Resonance Imaging - May 30, 2013 Category: Radiology Authors: Guillaume Madelin, Ravinder R. Regatte Tags: Review Source Type: research

Global informetric perspective studies on translational medical research
Conclusions: The subject categories of "Research & Experimental Medicine", "Medical Laboratory Technology", and "General & Internal Medicine" play a key role in translational medical research both in production and in its networks. Translational medical research and CTS, etc. are core journals of translational research. G7 countries are the leading nations for translational medical research. Some developing countries, such as P.R China, also play an important role in the communication of translational research. The USA and its institutions play a dominant role in the production, collaboration, citations and high quality ar...
Source: BMC Medical Informatics and Decision Making - Latest articles - July 26, 2013 Category: Information Technology Authors: Qiang YaoPeng-Hui LyuFei-Cheng MaLan YaoShi-Jing Zhang Source Type: research

Teen drinking linked to raised breast cancer risk
Conclusion Alcohol consumption is already recognised as a risk factor for breast cancer. And this large, well-conducted study seems to confirm that young women between their first period and first pregnancy are particularly susceptible. One limitation of the study is that the women were asked to recall their drinking habits when they were far younger, which could mean the results are less reliable. Also, other factors called confounders might have affected women’s risk of breast cancer, although researchers did adjust their findings for a range of other risk factors. As the authors point out, it is crucial that youn...
Source: NHS News Feed - August 29, 2013 Category: Consumer Health News Tags: Cancer Lifestyle/exercise Source Type: news

Electrolyte imbalance triggering relapse of inflammatory neuropathy
We describe a case of a 71 year old female with a fourteen year history of chronic inflammatory demyelinating polyneuropathy (CIDP) and stable monoclonal gammopathy, normally maintained on three–weekly intravenous immunoglobulin (IVIG) therapy. At her best baseline, she has a normal motor examination and reduced vibration sense only to the ankles. She presented with a four week history of progressive numbness and paresthesiae in all four limbs, reduced balance, a decline in mobility with frequent falls and reduced hand function. The deterioration developed after a week of non–bloody diarrhoea with night sweats ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Keshavan, A., Gandhi, S., Lunn, M., Reilly, M. Tags: Neurogastroenterology, Immunology (including allergy), Drugs: CNS (not psychiatric), Multiple sclerosis, Neuromuscular disease, Peripheral nerve disease, Stroke, Hypertension Association of British Neurologists (ABN) joint meeting with the Royal College Source Type: research

Clinical Features of Radiation-induced Carotid Atherosclerosis.
Abstract Carotid arteries frequently receive significant incidental doses of radiation during the treatment of malignant diseases, including head and neck cancer, breast cancer and lymphoma. Vascular injury after treatment may result in carotid artery stenosis and increased risk of neurological sequelae, such as stroke and transient ischaemic attack. The long latent interval from treatment to the development of clinical complications makes investigation of this process difficult, particularly in regard to the design of interventional clinical studies. Nevertheless, there is compelling clinical evidence that radiat...
Source: Clinical Genitourinary Cancer - November 1, 2013 Category: Cancer & Oncology Authors: Gujral DM, Shah BN, Chahal NS, Senior R, Harrington KJ, Nutting CM Tags: Clin Oncol (R Coll Radiol) Source Type: research

Effects of Catecholamines on Microcirculation During General Inhalation Anesthesia
Conclusions: During general anesthesia with sevoflurane, the infusion of clinical dosages of norepinephrine and dobutamine did not alter sublingual perfusion, although the expected systemic hemodynamic alterations were induced.
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 22, 2013 Category: Anesthesiology Authors: Paolo Chiarandini, Livia Pompei, Maria Gabriella Costa, Luigi Vetrugno, Fortunato Ronga, Roberta Contin, Fabio Rosa, Giorgio Della Rocca Tags: Original Article Source Type: research

Clinical Features of Radiation-induced Carotid Atherosclerosis
Abstract: Carotid arteries frequently receive significant incidental doses of radiation during the treatment of malignant diseases, including head and neck cancer, breast cancer and lymphoma. Vascular injury after treatment may result in carotid artery stenosis and increased risk of neurological sequelae, such as stroke and transient ischaemic attack. The long latent interval from treatment to the development of clinical complications makes investigation of this process difficult, particularly in regard to the design of interventional clinical studies. Nevertheless, there is compelling clinical evidence that radiation cont...
Source: Clinical Oncology - November 4, 2013 Category: Radiology Authors: D.M. Gujral, B.N. Shah, N.S. Chahal, R. Senior, K.J. Harrington, C.M. Nutting Tags: Overview Source Type: research

Daily calcium intake in excess of 1400 mg is associated with increased all-cause and cardiovascular disease mortality in women
Commentary on: Michaëlsson K, Melhus H, Warensjö Lemming E, et al.. Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study. BMJ 2013;346:f228. Implications for practice and research Greater calcium intake is encouraged for bone health, but has unclear cardiovascular consequences. In a large cohort of Swedish women, total calcium intake of <600 or ≥1400 mg/day was associated with an increased risk of total mortality (TM) and cardiovascular disease mortality (CVDM). It is important to emphasise adequate dietary calcium intake in...
Source: Evidence-Based Nursing - March 14, 2014 Category: Nursing Authors: Sesso, H. D., Wang, L. Tags: Drugs: cardiovascular system, Stroke, Diet, Breast cancer, Ischaemic heart disease, Clinical diagnostic tests Primary healthcare Source Type: research

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