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Total 216 results found since Jan 2013.

Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?
In this study we provide additional in vivo evidence showing that MF can effectively reduce the oxidative and inflammatory risk for stroke and attenuate post-ischemic brain injury promoted by TS and e-Cig vaping. Our data also suggest that MF administration could be extended as prophylactic care during the time window required for the renormalization of the risk levels of stroke following smoking cessation thus further studies in that direction are warrated. Graphical abstract
Source: Redox Biology - June 22, 2017 Category: Biology Source Type: research

Factors associated with post-stroke suicidal death
Conclusions The risk of suicidal death is approximately 2 times higher than that in the general population. Depression, diabetes, and large lesions in specific locations should be considered in the implementation of suicide prevention strategies in stroke patients.
Source: Journal of Psychiatric Research - October 14, 2017 Category: Psychiatry Source Type: research

FES for abnormal movement of upper limb during walking in post-stroke subjects.
CONCLUSIONS: The present study showed that a traditional foot drop functional electrical stimulator providing stimulation also to the patient's upper limbs, while being triggered by a foot switch under his or her heel, can help the patient to swing the arms and reduce the foot drop. The method has significant effect on traditional foot drop therapy. The subjects' high degree of acceptance and willingness to commit to long-term use showed that the method is indeed worthy of further research. PMID: 24934709 [PubMed - as supplied by publisher]
Source: Technology and Health Care - June 16, 2014 Category: Medical Equipment Authors: Chou CH, Hwang YS, Chen CC, Chen SC, Lai CH, Chen YL Tags: Technol Health Care Source Type: research

Nicotine pre-exposure reduces stroke-induced glucose transporter-1 activity at the blood–brain barrier in mice
Conclusions Nicotine pre-exposure reduced the IR-enhanced GLUT1 transporter function and expression at the BBB in a focal brain ischemia mouse model. These studies suggest that nicotine exposure prior to stroke could create an enhanced glucose deprived state at the neurovascular unit (NVU) and could provide an additional vulnerability to enhanced stroke injury.
Source: Fluids and Barriers of the CNS - April 29, 2015 Category: Neuroscience Source Type: research

E-191 Influence of socioeconomic factors on the development of post-stroke depression in aneurysmal subarachnoid hemorrhage survivors
ConclusionThe overall risk of developing a new depression disorder after aSAH was 16% in this retrospective study. The female sex was close to 4 times and substance use were six and half time more likely to develop new depressive symptoms; therefore, these risk factors should be considered when screening patients for depression after aSAH.Disclosures D. Lim: None. C. Abdi: None. L. George: None. K. Lim: None. M. Amruthur: None. A. Gonzalez: None. K. Prijoles: None. H. Haughn: None. J. Keen: None. E. Federico: None. C. Galang: None. B. Gulek: None. D. Bass: None. R. Meyer: None. D. Coppel: None. C. Kelly: None. L. Kim: None. M. Levitt: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lim, D., Abdi, C., George, L., Lim, K., Amruthur, M., Gonzalez, A., Prijoles, K., Haughn, H., Keen, J., Federico, E., Galang, C., Gulek, B., Bass, D., Meyer, R., Coppel, D., Kelly, C., Kim, L., Levitt, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Stroke patients at heightened risk of attempting suicide
Stroke patients can be up to twice as likely to commit suicide compared with the rest of the population, and the risk of attempted suicide is highest within the first two years after a stroke.
Source: Nursing Times Breaking News - April 10, 2015 Category: Nursing Source Type: news

Dual Vaping and Smoking Tied to Elevated Stroke Risk in Younger Adults Dual Vaping and Smoking Tied to Elevated Stroke Risk in Younger Adults
Young and middle-aged adults who vape and smoke are more likely to have had a stroke than those who use only one of these types of nicotine product, or none at all, a study suggests.Reuters Health Information
Source: Medscape Medical News Headlines - January 18, 2020 Category: Consumer Health News Tags: Public Health & Prevention News Source Type: news

Impact of Electronic Cigarette Vaping on Cerebral Ischemia: What We Know So Far
AbstractElectronic cigarettes (ECs) are battery-powered nicotine delivery devices that have rapidly gained popularity and attention globally. ECs work by heating a liquid to produce an aerosol that usually contains nicotine, flavoring compounds, and other chemicals, which are inhaled during vaping. EC aerosols are depicted to contain a lower number and overall quantity of harmful toxicants than conventional cigarettes (CCs). However, emerging research indicates that EC aerosols contain harmful ingredients including ultrafine particles, volatile organic compounds, and heavy metals. One common ingredient found in both CCs an...
Source: Translational Stroke Research - April 18, 2022 Category: Neurology Source Type: research

Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome
ConclusionsThese results suggest that JUUL exposure could negatively impact the cerebrovascular system, although to a lesser extent than TS exposure.
Source: Fluids and Barriers of the CNS - September 9, 2022 Category: Neuroscience Source Type: research

Member States commit to reduce preventable deaths from heart disease and stroke, cancer, diabetes and lung disease
UN Member States have reaffirmed their commitment to take bold measures to reduce the avoidable burden of noncommunicable diseases (NCDs). These ailments, including heart disease and stroke, cancer, diabetes and lung disease kill 38 million people every year, many of them before they reach the age of 70. Most of these largely preventable deaths occur in developing countries, where this epidemic threatens to undermine social and economic development. Member States, gathered for the second time in 3 years at the United Nations in New York to discuss this topic, pledged to intensify efforts to combat the growing menace of NCD...
Source: WHO news - July 11, 2014 Category: Global & Universal Tags: cervical cancer, cervical cancer, infectious diseases, infectious diseases, diabetes mellitus, hyperglycaemia, glucose intolerance, diabetes mellitus, hyperglycaemia, glucose intolerance, chronic diseases, chronic diseases, cerebrovascular accident, cva, Source Type: news

Nicotine pre-exposure reduces stroke-induced glucose transporter-1 activity at the blood–brain barrier in mice
In this study, we investigated the effects of nicotine on carrier-mediated glucose transport into ischemic brain. Specifically, the present study investigates glucose transporter-1 (GLUT1) function and expression at the BBB in a focal brain ischemia model of mice pre-exposed to nicotine. Methods: Nicotine was administrated subcutaneously by osmotic pump at the dose of 4.5 mg/kg/day for 1, 7, or 14 days to reflect the plasma levels seen in smokers. Ischemic-reperfusion (IR) injury was induced by 1 h transient middle cerebral artery occlusion (tMCAO) and 24 h reperfusion. Glucose transport was estimated using an in situ ...
Source: Cerebrospinal Fluid Research - April 29, 2015 Category: Neurology Authors: Kaushik ShahPurushotham BoreddyThomas Abbruscato Source Type: research

Member states commit to reduce preventable deaths from heart disease and stroke, cancer, diabetes and lung disease.
Authors: Epstein D PMID: 25438398 [PubMed - indexed for MEDLINE]
Source: Central European Journal of Public Health - June 3, 2015 Category: Global & Universal Tags: Cent Eur J Public Health Source Type: research

Vaping and smoking tied to stroke risk in younger adults
Young and middle-aged adults who vape and smoke are more likely to have had a stroke than those who use only one of these types of nicotine product, or none at all, a study suggests.
Source: Reuters: Health - January 16, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

Enriched environment alleviates post-stroke cognitive impairment through enhancing α7-nAChR expression in rats
Conclusions: EE markedly improves cognitive impairment and enhances neuroplasticity in PSCI rats, which may be closely related to enhancement of α 7-nAChR expression.RESUMO Introdu ção: O ambiente enriquecido (AE) é uma intervenção simples e eficaz para melhorar a função cognitiva no comprometimento cognitivo pós-AVC, em parte devido ao reequilíbrio da via de sinalização colinérgica no hipocampo. O receptor nicotínico α 7 de acetilcolina ( α 7-nAChR) é um receptor colinérgico cuja ativação inibe inflamação e promove a recuperação da função neurológica em pacientes com comprometimento cognitivo pÃ...
Source: Arquivos de Neuro-Psiquiatria - November 2, 2020 Category: Neurology Source Type: research