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Total 129 results found since Jan 2013.

Thrombolysis in Patients With Mild Stroke: Results From the Austrian Stroke Unit Registry Clinical Sciences
Conclusions— In our study, intravenous rt-PA treatment was beneficial for patients with mild deficit. Given the observational nature of these results, our data might serve as an incentive for future randomized controlled trials to provide a basis for optimal patient selection.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Greisenegger, S., Seyfang, L., Kiechl, S., Lang, W., Ferrari, J., on behalf of the Austrian Stroke Unit Registry Collaborators Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Sex-Related Differences of Acute Stroke Unit Care: Results From the Austrian Stroke Unit Registry Clinical Sciences
Conclusions— We identified no disproportions in quality of care in the acute SU setting between men and women, but the outcome was significantly different. Further studies on the poststroke period including socioeconomic aspects are needed to clarify this finding.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Gattringer, T., Ferrari, J., Knoflach, M., Seyfang, L., Horner, S., Niederkorn, K., Culea, V., Beitzke, M., Lang, W., Enzinger, C., Fazekas, F. Tags: Acute Cerebral Infarction, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Predictive value of ABCD2 and ABCD3-I scores in TIA and minor stroke in the stroke unit setting
Conclusions: Standard ABCD2 and ABCD3-I scores are useful instruments to estimate the probability of early and 3-month stroke in TIA and minor stroke patients treated at specialized stroke units, with C, D, and I being the most important score components in this setting.
Source: Neurology - August 28, 2016 Category: Neurology Authors: Knoflach, M., Lang, W., Seyfang, L., Fertl, E., Oberndorfer, S., Daniel, G., Seifert-Held, T., Brainin, M., Krebs, S., Matosevic, B., Töll, T., Kiechl, S., Willeit, J., Ferrari, J., For the Austrian Stroke Unit Collaborators Tags: ARTICLE Source Type: research

Weather as physiologically equivalent was not associated with ischemic stroke onsets in Vienna, 2004-2010.
Abstract Stroke rates were found to have seasonal variations. However, previous studies using air temperature, humidity, or air pressure separately were not adequate, and the study catchment was not clearly drawn. Therefore, here we proposed to use a thermal index called physiologically equivalent temperature (PET) that incorporates air temperature, humidity, wind speed, cloud cover, air pressure and radiation flux from a biometeorological approach to estimate the effect of weather as physiologically equivalent on ischemic stroke onsets in an Austrian population. Eight thousand four hundred eleven stroke events in...
Source: Environmental Science and Pollution Research International - April 16, 2015 Category: Environmental Health Authors: Ferrari J, Shiue I, Seyfang L, Matzarakis A, Lang W, Austrian Stroke Registry Collaborators Tags: Environ Sci Pollut Res Int Source Type: research

Comment on: External Validation of the PREMISE Score in the Athens Stroke Registry
This study externally validated our proposed predicting early mortality from ischemic stroke (PREMISE) score, derived from the nationwide Austrian Stroke Unit registry.2 While we feel obliged to point out that the original PREMISE score publication2 was incorrectly referenced3 by Ntaios et al, it is reassuring that the authors confirmed prognostic accuracy (with excellent calibration and good discrimination) of the PREMISE score as an instrument for predicting early (within one week after admission) death after ischemic stroke in 2608 patients from the Athens Stroke Unit registry.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2019 Category: Neurology Authors: Thomas Gattringer, Alexandra Posekany, Stefan Kiechl, Franz Fazekas, Christian Enzinger Tags: Letter to the Editor Source Type: research

Etiologic Evaluation of Ischemic Stroke in Young Adults: A Comparative Study between Two European Centers
Introduction: Identifying the cause of ischemic stroke in young adults is often difficult. Our objective was to compare the etiologic diagnostic strategy for ischemic stroke in young adults between 2 European centers and investigate the influence of workup variations in the diagnosed etiologies. Patients and Methods: We included patients aged 18-55 years admitted for ischemic stroke or transient ischemic attack to the stroke units of Santa Maria Hospital in Lisbon, Portugal, and Innsbruck University Hospital in Innsbruck, Austria, between 2014 and 2016.
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2019 Category: Neurology Authors: Bernardo Crespo Pimentel, Johann Willeit, Thomas T öll, Stefan Kiechl, Teresa Pinho e Melo, Patrícia Canhão, Catarina Fonseca, José Ferro Source Type: research

External Validation of the PREMISE Score in the Athens Stroke Registry
Background: A simple score was proposed recently for Predicting Early Mortality from Ischemic Stroke (PREMISE) derived from the Austrian Stroke Unit Registry. This score could be useful in clinical practice and research. However, its generalizability is uncertain, as it was validated internally only. Aims: We aimed to validate the PREMISE score externally. Methods: The analysis was performed in the Athens Stroke Registry. The PREMISE score was calculated as described in the original publication.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2019 Category: Neurology Authors: George Ntaios, George Georgiopoulos, Eleni Koroboki, Konstantinos Vemmos Source Type: research

Fitness and cognition in the elderly: The Austrian Stroke Prevention Study
Conclusions: Higher Vo2max is associated with better global cognitive function and with better performance in the cognitive domains of memory, executive function, and motor skills in the middle-aged and elderly. The association is not mediated by the presence of white matter lesions, lacunes, and brain atrophy.
Source: Neurology - February 1, 2016 Category: Neurology Authors: Freudenberger, P., Petrovic, K., Sen, A., Toglhofer, A. M., Fixa, A., Hofer, E., Perl, S., Zweiker, R., Seshadri, S., Schmidt, R., Schmidt, H. Tags: MRI, All Cerebrovascular disease/Stroke, Cognitive aging, Cohort studies ARTICLE Source Type: research

Cell-Based Therapies for Stroke: Promising Solution or Dead End? Mesenchymal Stem Cells and Comorbidities in Preclinical Stroke Research
Conclusion The high prevalence of comorbidities in patients with stroke indicates the need for therapies in preclinical studies that take into account these comorbidities in order to avoid failures in translation to the patient. Preclinical studies are beginning to evaluate the efficacy of MSC treatment in stroke associated with comorbidities, especially hypertension, for ischemic and hemorrhagic stroke. Regarding aging and diabetes, only ischemic stroke studies have been performed. For the moment, few studies have been performed and contradictory results are being reported. These contradictory results may be due to the u...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II
Conclusion: In ischemic stroke or TIA patients with platelet count within normal range, platelet count may be a qualified predictor for long-term recurrent stroke, mortality, and poor functional outcome. Introduction Platelets exert a critical role in the pathogenesis of atherosclerotic complications of cardio-cerebrovascular disease, contributing to thrombus formation, and embolism (1, 2). Previous literature reported that platelets of various size and density are produced by megakaryocytes of different size and stages of maturation in different clinical conditions, suggesting various platelet patterns in differen...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

ABCD3-I score and the risk of early or 3-month stroke recurrence in tissue- and time-based definitions of TIA and minor stroke
AbstractChanging definition of TIA from time to a tissue basis questions the validity of the well-established ABCD3-I risk score for recurrent ischemic cerebrovascular events. We analyzed patients with ischemic stroke with mild neurological symptoms arriving<  24 h after symptom onset in a phase where it is unclear, if the event turns out to be a TIA or minor stroke, in the prospective multi-center Austrian Stroke Unit Registry. Patients were retrospectively categorized according to a time-based (symptom duration below/above 24 h) and tissue-based (wi thout/with corresponding brain lesion on CT or MRI) definition of ...
Source: Journal of Neurology - January 11, 2018 Category: Neurology Source Type: research

Thrombolysis and clinical outcome in patients with stroke after implementation of the Tyrol Stroke Pathway: a retrospective observational study
Publication date: Available online 28 November 2014 Source:The Lancet Neurology Author(s): Johann Willeit , Theresa Geley , Johannes Schöch , Heinrich Rinner , Andreas Tür , Hans Kreuzer , Norbert Thiemann , Michael Knoflach , Thomas Toell , Raimund Pechlaner , Karin Willeit , Natalie Klingler , Silvia Praxmarer , Michael Baubin , Gertrud Beck , Klaus Berek , Christian Dengg , Klaus Engelhardt , Thomas Erlacher , Thomas Fluckinger , Wilhelm Grander , Josef Grossmann , Hermann Kathrein , Norbert Kaiser , Benjamin Matosevic , Heinrich Matzak , Markus Mayr , Robert Perfler , Werner Poewe , Alexandra Rauter , Gudrun Schoen...
Source: The Lancet Neurology - December 8, 2014 Category: Neurology Source Type: research

The efficacy of thrombolysis in lacunar stroke – evidence from the Austrian Stroke Unit Registry
ConclusionsPatients with both lacunar and non‐lacunar stroke benefitted from ivT. The degree of improvement was similar in both groups.
Source: European Journal of Neurology - April 27, 2017 Category: Neurology Authors: C. C. J. Eggers, C. Bocksrucker, L. Seyfang, Tags: Original Article Source Type: research

Time trends in stroke severity in the years 2005 to 2020: results from the Austrian Stroke Unit Registry
ConclusionDespite an aging population and generally increasing AF frequency, we observed a consistent trend towards less disabling strokes on admission.
Source: Journal of Neurology - March 21, 2022 Category: Neurology Source Type: research

Prediction of late seizures after ischaemic stroke with a novel prognostic model (the SeLECT score): a multivariable prediction model development and validation study
Publication date: February 2018 Source:The Lancet Neurology, Volume 17, Issue 2 Author(s): Marian Galovic, Nico Döhler, Barbara Erdélyi-Canavese, Ansgar Felbecker, Philip Siebel, Julian Conrad, Stefan Evers, Michael Winklehner, Tim J von Oertzen, Hans-Peter Haring, Anna Serafini, Giorgia Gregoraci, Mariarosaria Valente, Francesco Janes, Gian Luigi Gigli, Mark R Keezer, John S Duncan, Josemir W Sander, Matthias J Koepp, Barbara Tettenborn Background Stroke is one of the leading causes of acquired epilepsy in adults. An instrument to predict whether people are at high risk of developing post-stroke seizures is not availab...
Source: The Lancet Neurology - January 18, 2018 Category: Neurology Source Type: research