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Specialty: Internal Medicine
Condition: Atrial Fibrillation

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Total 509 results found since Jan 2013.

Atrial Fibrillation Is Associated with Cognitive Impairment, All-Cause Dementia, Vascular Dementia, and Alzheimer ’s Disease: a Systematic Review and Meta-Analysis
ConclusionAF increases the risk of cognitive impairment, all-cause dementia, vascular dementia, and Alzheimer ’s disease. Future studies should employ interventions that may delay or even prevent cognitive decline in AF patients.
Source: Journal of General Internal Medicine - July 9, 2021 Category: Internal Medicine Source Type: research

Reflux esophagitis is associated with higher risks of acute stroke and transient ischemic attacks in patients hospitalized with atrial fibrillation: A nationwide inpatient sample analysis
Reflux esophagitis (RE) is a subset of gastroesophageal reflux disease (GERD) with endoscopic evidence of esophageal inflammation, which has been linked to an increased incidence of atrial fibrillation (AF). However, data on the effect of RE on patient outcomes is limited. We sought to examine the potential association of RE with outcomes of patients with AF in a nationwide study. The National Inpatient Sample (NIS) database was queried to identify hospitalized adult patients with AF and RE between 2010 and 2014. Primary outcomes included inpatient mortality, length of stay (LOS), and total hospital charges. AF related ...
Source: Medicine - June 25, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Meta-analysis of patent foramen ovale closure versus medical therapy for prevention of recurrent ischemic neurological events: Impact of medication type
Conclusions With the addition of anticoagulants, the benefit of PFO closure decreased gradually. Patient groups that adopt individualized medical therapy strategies may benefit more.
Source: Medicine - June 25, 2021 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Device-detected atrial high rate episodes and the risk of stroke/thrombo-embolism and atrial fibrillation incidence: a systematic review and meta-analysis
CONCLUSIONS: AHRE are significantly associated with systemic thromboembolism and incident clinical AF. Further studies are needed to improve patients' risk stratification and management.PMID:34154879 | DOI:10.1016/j.ejim.2021.05.038
Source: European Journal of Internal Medicine - June 22, 2021 Category: Internal Medicine Authors: Marco Vitolo Jacopo F Imberti Anna Maisano Alessandro Albini Niccol ò Bonini Anna Chiara Valenti Vincenzo L Malavasi Marco Proietti Jeff S Healey Gregory Yh Lip Giuseppe Boriani Source Type: research

Low bleeding and thromboembolic risk with continued dabigatran during cardiovascular interventions: the GLORIA-AF study
CONCLUSIONS: More than two thirds of the interventions were performed with uninterrupted dabigatran therapy, of which most were AF-cardioversions. Uninterrupted dabigatran therapy was associated with low major bleeding and stroke/systemic embolism risk, supporting the favourable safety and effectiveness profile of dabigatran in clinical practice-based settings.PMID:34120814 | DOI:10.1016/j.ejim.2021.05.020
Source: European Journal of Internal Medicine - June 14, 2021 Category: Internal Medicine Authors: Sake J van der Wall Gregory Y H Lip Christine Teutsch Oskars Kalejs Philippe Lyrer Christian Hall Sergio J Dubner Hans-Christoph Diener Jonathan L Halperin Chang Sheng Ma Kenneth J Rothman Kristina Zint Dongmei Zhai Menno V Huisman GLORIA-AF Investigators Source Type: research

Intracardiac thrombus in a patient with mitral bioprosthesis and atrial fibrillation treated with direct oral anticoaugulant: A case report
Rationale: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased morbidity, especially stroke and heart failure. There is also increasing awareness that atrial fibrillation is a major cause of embolic events which in 75% of cases are complicated by cerebrovascular accidents. Patient concerns: A 50-year-old woman with mitral bioprosthesis under warfarin for nonvalvular atrial fibrillation was referred to our Coronary Intensive Care Unit due to acute myocardial infarction without evidence of significant coronary artery stenosis. Diagnoses: Cardiovascular examination...
Source: Medicine - June 11, 2021 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Off-label reduced-dose apixaban does not reduce hemorrhagic risk in Taiwanese patients with nonvalvular atrial fibrillation: A retrospective, observational study
East Asians are reportedly at high risk of anticoagulant-related bleeding; therefore, some physicians prefer to prescribe low-dose direct oral anticoagulants (DOACs). Little is known about the therapeutic effectiveness and safety of off-label reduced-dose apixaban in East Asians with nonvalvular atrial fibrillation (AF). We aimed to investigate the effectiveness and safety of off-label reduced-dose apixaban in Taiwanese patients with nonvalvular AF. This retrospective cohort study enrolled 1073 patients with nonvalvular AF who took apixaban between July 2014 and October 2018 from 4 medical centers in southern Taiwan. Th...
Source: Medicine - June 11, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Association between exercise habits and stroke, heart failure, and mortality in Korean patients with incident atrial fibrillation: A nationwide population-based cohort study
by Hyo-Jeong Ahn, So-Ryoung Lee, Eue-Keun Choi, Kyung-Do Han, Jin-Hyung Jung, Jae-Hyun Lim, Jun-Pil Yun, Soonil Kwon, Seil Oh, Gregory Y. H. Lip BackgroundThere is a paucity of information about cardiovascular outcomes related to exercise habit change after a new diagnosis of atrial fibrillation (AF). We investigated the association between exercise habits after a new AF diagnosis and ischemic stroke, heart failure (HF), and all-cause death. Methods and findingsThis is a nationwide population-based cohort study using data from the Korea National Health Insurance Service. A retrospective analysis was performed for 66,692 pa...
Source: PLoS Medicine - June 8, 2021 Category: Internal Medicine Authors: Hyo-Jeong Ahn Source Type: research

Blood pressure-lowering treatment for the prevention of cardiovascular events in patients with atrial fibrillation: An individual participant data meta-analysis
ConclusionsIn this meta-analysis, we found that BP-lowering treatment reduces the risk of major cardiovascular events similarly in individuals with and without AF. Pharmacological BP lowering for prevention of cardiovascular events should be recommended in patients with AF.
Source: PLoS Medicine - June 1, 2021 Category: Internal Medicine Authors: Ana-Catarina Pinho-Gomes Source Type: research

Refining age stratum of the C < sub > 2 < /sub > HEST score for predicting incident atrial fibrillation in a hospital-based Chinese population
CONCLUSION: In a hospital-based Chinese population, by refining the age strata of the original C2HEST score, the mC2HEST score had significantly increased predictive accuracy and discriminative capability for incident AF. The clinical benefits of the application of novel mC2HEST score needs further validation in multiple settings.PMID:33975769 | DOI:10.1016/j.ejim.2021.04.014
Source: European Journal of Internal Medicine - May 12, 2021 Category: Internal Medicine Authors: Yan-Guang Li Jin Bai Gongbu Zhou Juan Li Yi Wei Lijie Sun Lingyun Zu Shuwang Liu Source Type: research

Validation of the AF-ESUS score to identify patients with embolic stroke of undetermined source and low risk of device-detected atrial fibrillation
Eur J Intern Med. 2021 May 2:S0953-6205(21)00116-3. doi: 10.1016/j.ejim.2021.04.003. Online ahead of print.NO ABSTRACTPMID:33952425 | DOI:10.1016/j.ejim.2021.04.003
Source: European Journal of Internal Medicine - May 6, 2021 Category: Internal Medicine Authors: Alkisti Kitsiou Dimitrios Sagris Wolf-R üdiger Schäbitz George Ntaios Source Type: research