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Condition: Stroke
Procedure: Angioplasty

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Total 4288 results found since Jan 2013.

Safety of percutaneous coronary intervention in patients with acute ischemic stroke/transient ischemic attack and acute coronary syndrome
Conclusions The primary and secondary end points were not enhanced in patients undergoing PCI. Therefore PCI is safe in patients with stroke/TIA and concomitant ACS.
Source: Clinical Research in Cardiology - October 29, 2015 Category: Cardiology Source Type: research

Prevalence, Risk Factors, and Clinical Significance of Asymptomatic Extracranial Vertebral Artery Disease in Patients with Symptomatic Internal Carotid Artery Stenosis: Analysis of Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) Trial (S42.002)
Conclusions: There appears to be an increased risk of stroke and death in patients with symptomatic internal carotid artery stenosis with concurrent asymptomatic extracranial vertebral artery stenosis. Key words: Extracranial vertebral artery; carotid stenosis; vertebral artery stenosis; vertebral artery occlusion; stroke; death.Disclosure: Dr. Qureshi has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. Jansen has nothing to disclose. Dr. Eckstein has nothing to disclose. Dr. Ringleb has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Qureshi, A., Chaudhry, S., Jansen, O., Eckstein, H.-H., Ringleb, P. Tags: Stroke Mechanism and Modifiers Source Type: research

Mortality of patients with previous stroke undergoing drug-eluting stent implantation
Objective: Patients with previous stroke are increasing among patients receiving percutaneous coronary intervention (PCI) with drug-eluting stents (DES); however, data about the influence of previous stroke on patient outcomes are limited. We evaluated whether previous stroke is associated with increased risk for mortality in coronary artery disease. Patients and methods: A total of 18 650 patients with coronary artery disease undergoing PCI with DES were enrolled. Databases from three real-world PCI registries were merged for a patient-level meta-analysis. The primary outcome was death from any cause. The secondary out...
Source: Coronary Artery Disease - October 5, 2017 Category: Cardiology Tags: Original Research Source Type: research

Long term durability and outcomes of carotid stenting and carotid endarterectomy
Conclusions Although CAS may be more strongly associated with periprocedural stroke/death compared with CEA, it could be a good alternative to CEA in terms of long term durability and outcomes.
Source: Journal of NeuroInterventional Surgery - July 12, 2017 Category: Neurosurgery Authors: Jung, J.-M., Choi, J.-Y., Kim, H. J., Suh, S.-i., Seo, W.-K. Tags: Ischemic stroke Source Type: research

Combination Therapy with Dipyridamole and Clopidogrel for Secondary Stroke Prevention in Aspirin-Intolerant Patients After Myocardial Infarction: Results of a Nationwide Case-Control Study
ConclusionNo differences were observed in the 12-year survival rate between clopidogrel and clopidogrel –dipyridamole groups. The two groups had balanced event-free survival in recurrent stroke, ICH, GI bleeding, and myocardial infarction.
Source: CNS Drugs - January 16, 2019 Category: Neurology Source Type: research

Medical and Endovascular Treatments for Intracranial Atherosclerotic Stenosis: A Network Meta-Analysis
AbstractMedical treatment and endovascular therapy are widely used for intracranial atherosclerotic stenosis, but the best treatment strategy remains uncertain. The goal of this study was to compare the safety and effectiveness of medical treatment, stenting, and primary balloon angioplasty (PBA). We searched PubMed, MEDLINE, and EMBASE for trials comparing these three treatments for intracranial stenosis up to December 24, 2020. We performed a network meta-analysis with random-effects models. The primary outcome was any stroke or death during a long-term follow-up. Secondary outcomes included ischemic stroke, intracranial...
Source: Translational Stroke Research - November 18, 2021 Category: Neurology Source Type: research

Stroke Prevention in Symptomatic Large Artery Intracranial Atherosclerosis Practice Advisory: Report of the AAN Guideline Subcommittee
Neurology. 2022 Mar 22;98(12):486-498. doi: 10.1212/WNL.0000000000200030.ABSTRACTBACKGROUND AND OBJECTIVES: To review treatments for reducing the risk of recurrent stroke or death in patients with symptomatic intracranial atherosclerotic arterial stenosis (sICAS).METHODS: The development of this practice advisory followed the process outlined in the American Academy of Neurology Clinical Practice Guideline Process Manual, 2011 Edition, as amended. The systematic review included studies through November 2020. Recommendations were based on evidence, related evidence, principles of care, and inferences.MAJOR RECOMMENDATIONS: ...
Source: Atherosclerosis - March 22, 2022 Category: Cardiology Authors: Tanya N Turan Osama O Zaidat Gary S Gronseth Marc I Chimowitz Antonio Culebras Anthony J Furlan Larry B Goldstein Nestor R Gonzalez Julius G Latorre Steven R Mess é Thanh N Nguyen Rajbeer S Sangha Michael J Schneck Aneesh B Singhal Lawrence R Wechsler Al Source Type: research

Protein Biomarkers in Blood Reflect the Interrelationships Between Stroke Outcome, Inflammation, Coagulation, Adhesion, Senescence and Cancer
Cell Mol Neurobiol. 2022 Aug 11. doi: 10.1007/s10571-022-01260-1. Online ahead of print.ABSTRACTThe most important predictors for outcomes after ischemic stroke, that is, for health deterioration and death, are chronological age and stroke severity; gender, genetics and lifestyle/environmental factors also play a role. Of all these, only the latter can be influenced after the event. Recurrent stroke may be prevented by antiaggregant/anticoagulant therapy, angioplasty of high-grade stenoses, and treatment of cardiovascular risk factors. Blood cell composition and protein biomarkers such as C-reactive protein or interleukins...
Source: Cellular and Molecular Neurobiology - August 11, 2022 Category: Cytology Authors: Georg Fuellen Uwe Walter Larissa Henze Jan B öhmert Daniel Palmer Soyoung Lee Clemens A Schmitt Henrik Rudolf Axel Kowald Source Type: research

Impact of clopidogrel and potent P2Y 12 -inhibitors on mortality and stroke in patients with acute coronary syndrome or undergoing percutaneous coronary intervention. A systematic review and meta-analysis.
Abstract Administration of a P2Y 12 -receptor antagonist in addition to aspirin is mandatory in patients with acute coronary syndromes (ACS) or undergoing percutaneous coronary intervention (PCI) to reduce the occurrence of thrombotic events; however, their impact on mortality and stroke is unclear. We aimed to evaluate the influence of moderate (clopidogrel) or potent (prasugrel/ticagrelor) P2Y 12 -receptor inhibition on major cardiovascular outcomes among patients with ACS or undergoing PCI. Systematic literature search was performed to find randomised, controlled clinical trials comparing the clinical impact o...
Source: Thrombosis and Haemostasis - January 8, 2013 Category: Hematology Authors: Aradi D, Komócsi A, Vorobcsuk A, Serebruany VL Tags: Thromb Haemost Source Type: research

Clampless off-pump surgery reduces stroke in patients with left main disease
Conclusions: This study shows the superiority of OPCAB for patients with LMD with regards to risk-adjusted outcomes other than mortality. A “clampless OPCAB strategy”, effectively reduces stroke yielding similar early outcomes as PCI.
Source: International Journal of Cardiology - June 25, 2012 Category: Cardiology Authors: Maximilian Y. Emmert, Sacha P. Salzberg, Burkhardt Seifert, Jacques Scherman, Andre Plass, Christoph T. Starck, Oliver Theusinger, Simon P. Hoerstrup, Jürg Grünenfelder, Stephan Jacobs, Volkmar Falk Tags: Original Articles Source Type: research

Reperfusion therapy of acute ischaemic stroke and acute myocardial infarction: similarities and differences
The evolution of reperfusion therapy in acute myocardial infarction and acute ischaemic stroke has many similarities: thrombolysis is superior to placebo, intra-arterial thrombolysis is not superior to intravenous (i.v.), facilitated intervention is of questionable value, and direct mechanical recanalization without thrombolysis is proven (myocardial infarction) or promising (stroke) to be superior to thrombolysis—but only when started with no or minimal delay. However, there are also substantial differences. Direct catheter-based thrombectomy in acute ischaemic stroke is more difficult than primary angioplasty (in S...
Source: European Heart Journal - January 14, 2014 Category: Cardiology Authors: Widimsky, P., Coram, R., Abou-Chebl, A. Tags: ESC 2013 Andreas Gr[uuml ]ntzig Lecture Source Type: research

Carotid Stenting: Is There an Operator Effect? A Pooled Analysis From the Carotid Stenting Trialists' Collaboration Clinical Sciences
Conclusions— Carotid stenting should only be performed by operators with annual procedure volume ≥6 cases per year.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Calvet, D., Mas, J.-L., Algra, A., Becquemin, J.-P., Bonati, L. H., Dobson, J., Fraedrich, G., Jansen, O., Mali, W. P., Ringleb, P. A., Chatellier, G., Brown, M. M., Carotid Stenting Trialists' Collaboration (CSTC)--Writing Committee:, Calvet, Mas, Algra, Tags: Secondary prevention, Angioplasty and Stenting Clinical Sciences Source Type: research

Cerebral Nitinol Stenting in Progressive Stroke and in Crescendo TIAs
Conclusion PTAS should be considered a treatment option in case of progressive stroke or crescendo TIAs coupled with appropriate anatomical findings. This may allow for a substantial improvement in functional and neurologic status.[...]Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  Full text
Source: Journal of Neurological Surgery Part A: Central European Neurosurgery - September 9, 2015 Category: Neurosurgery Authors: Cohen-Inbar, OrAmsalem, Yaaqov Tags: Technical Note Source Type: research