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Condition: Stroke
Procedure: Gastroschisis Repair

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Total 4990 results found since Jan 2013.

Mitochondrial transplantation and immune response of human bone marrow mesenchymal stem cells for the Therapeutic of ischemic stroke
Curr Stem Cell Res Ther. 2023 May 5. doi: 10.2174/1574888X18666230505103407. Online ahead of print.ABSTRACTIschemic stroke is the leading cause of death and disability worldwide, with increasing incidence and mortality, imposing a significant social and economic burden on patients and their families. However, cerebral vascular occlusion leads to acute loss of neurons and destruction of synaptic structures. The limited treatment options cannot adequately address intra-neuronal mitochondrial dysfunction due to stroke. Therefore, stem cell-derived mitochondria transplantation plays an important role in neuronal protection and...
Source: Cell Research - May 8, 2023 Category: Cytology Authors: Yidong Liao Jiang Ming Wenxue Song Guangtang Chen Junshuan Cui Longcai He Zili Wang Xudong Wang Mingsong Xiong Hua Yang Kaya Xu Source Type: research

Nonpharmacological Treatments for Hospitalized Patients with Stroke: A Nuanced Approach to Prescribing Early Activity
AbstractStroke remains a leading cause of adult disability. To date, hyperacute revascularization procedures reach 5 –10% of stroke patients even in high resource health systems. There is a limited time window for brain repair after stroke, and therefore, the activities such as prescribed exercise in the earliest period will likely have long-term significant consequences. Clinicians who provide care for hospita lized stroke patients make treatment decisions specific to activity often without guidelines to direct these prescriptions. This requires a balanced understanding of the available evidence for early post-stroke ...
Source: Neurotherapeutics - June 8, 2023 Category: Neurology Source Type: research

Transgenic Overproduction of Omega-3 Polyunsaturated Fatty Acids Provides Neuroprotection and Enhances Endogenous Neurogenesis after Stroke.
Abstract Strokes are devastating as there are no current therapies to prevent the long term neurological deficits that they cause. Soon after ischemic stroke, there is proliferation and differentiation of neural stem/progenitor cells as an important mechanism for neuronal restoration. However, endogenous neurogenesis by itself is insufficient for effective brain repair after stroke as most newborn neurons do not survive. One fascinating strategy for stroke treatment would thus be maintaining the survival and/or promoting the differentiation of endogenous neural stem/progenitor cells. Using transgenic (Tg) mice ove...
Source: Current Molecular Medicine - August 22, 2013 Category: Molecular Biology Authors: Hu X, Zhang F, Leak RK, Zhang W, Iwai M, Stetler RA, Dai Y, Zhao A, Gao Y, Chen J Tags: Curr Mol Med Source Type: research

Spatial and Temporal Asymmetries in Gait Predict Split-Belt Adaptation Behavior in Stroke
Conclusion. This work demonstrates that stroke patients adapt toward their baseline temporal and spatial asymmetries of walking independently of one another. We define how a given split-belt training session would affect asymmetries in these domains, which must be considered when developing rehabilitation interventions for stroke patients.
Source: Neurorehabilitation and Neural Repair - February 11, 2014 Category: Neurology Authors: Malone, L. A., Bastian, A. J. Tags: Clinical Research Articles Source Type: research

Altered Resting-State Functional and White Matter Tract Connectivity in Stroke Patients With Dysphagia
Conclusions. Our results indicate that dysphagia secondary to stroke is associated with disruptive functional and structural integrity in the large-scale brain networks involved in motor control, thus providing new insights into the neural remodeling associated with this disorder.
Source: Neurorehabilitation and Neural Repair - February 11, 2014 Category: Neurology Authors: Li, S., Ma, Z., Tu, S., Zhou, M., Chen, S., Guo, Z., Gong, Q., He, L., Huang, X., Yao, D., Lui, S., Yu, B., Wang, X., Zhou, D., He, C. Tags: Clinical Research Articles Source Type: research

Omega-3 polyunsaturated fatty acids enhance cerebral angiogenesis and provide long-term protection after stroke.
Abstract Stroke is a devastating neurological disorder and one of the leading causes of death and serious disability. After cerebral ischemia, revascularization in the ischemic boundary zone provides nutritive blood flow as well as various growth factors to promote the survival and activity of neurons and neural progenitor cells. Enhancement of angiogenesis and the resulting improvement of cerebral microcirculation are key restorative mechanisms and represent an important therapeutic strategy for ischemic stroke. In the present study, we tested the hypothesis that post-stroke angiogenesis would be enhanced by omeg...
Source: Neurobiology of Disease - April 29, 2014 Category: Neurology Authors: Wang J, Shi Y, Zhang L, Zhang F, Hu X, Zhang W, Leak RK, Gao Y, Chen L, Chen J Tags: Neurobiol Dis Source Type: research

Functional Recovery After Ischemic Stroke Is Associated With Reduced GABAergic Inhibition in the Cerebral Cortex: A GABA PET Study
Conclusions: This is the first prospective, controlled longitudinal study showing that the change in GABA receptor availability over time is significantly related to motor recovery after stroke in humans. This work supports the rationale for a novel strategy to promote motor recovery after stroke.
Source: Neurorehabilitation and Neural Repair - June 13, 2014 Category: Neurology Authors: Kim, Y. K., Yang, E. J., Cho, K., Lim, J. Y., Paik, N.-J. Tags: Clinical Research Articles Source Type: research

Trunk Restraint to Promote Upper Extremity Recovery in Stroke Patients: A Systematic Review and Meta-Analysis
Conclusion. Trunk restraint has a moderate effect on reduction of upper extremity impairment in chronic stroke patients, in terms of FMA-UE score, increased shoulder flexion, and reduction in excessive trunk movement during reaching. There is insufficient evidence to demonstrate that trunk restraint improves upper extremity function and reaching trajectory smoothness and straightness in chronic stroke patients. Future research on stroke patients at different phases of recovery and with different levels of upper extremity impairment is recommended.
Source: Neurorehabilitation and Neural Repair - August 13, 2014 Category: Neurology Authors: Wee, S. K., Hughes, A.-M., Warner, M., Burridge, J. H. Tags: Clinical Research Articles Source Type: research

Variations in apolipoprotein D and sigma non-opioid intracellular receptor 1 genes with relation to risk, severity and outcome of ischemic stroke
Conclusions: We conclude that the SNP rs7659 within the APOD gene might be related to risk and severity of ischemic stroke in patients.
Source: BMC Neurology - September 28, 2014 Category: Neurology Authors: Håkan LövkvistAnn-Cathrin JönssonHolger LuthmanKatarina JoodChristina JernTadeusz WielochArne Lindgren Source Type: research

Bilateral Priming Before Wii-based Movement Therapy Enhances Upper Limb Rehabilitation and Its Retention After Stroke: A Case-Controlled Study
Conclusions. Bilateral priming before Wii-based Movement Therapy led to a greater magnitude and retention of improvement compared to control, especially measured with the FMA. These data suggest that bilateral priming can enhance the efficacy of Wii-based Movement Therapy, particularly for patients with low motor function after a stroke.
Source: Neurorehabilitation and Neural Repair - October 16, 2014 Category: Neurology Authors: Shiner, C. T., Byblow, W. D., McNulty, P. A. Tags: Clinical Research Articles Source Type: research

Measurement Properties of Streamlined Wolf Motor Function Test in Patients at Subacute to Chronic Stages After Stroke
Conclusions. The SWMFTs had sound hierarchical properties. The SWMFT-Chronic or the SWMFT-Subacute could be used to evaluate UE function of this subgroup at 9 to 12 months after stroke.
Source: Neurorehabilitation and Neural Repair - October 16, 2014 Category: Neurology Authors: Chen, H.-f., Wu, C.-y., Lin, K.-c., Jang, Y., Lin, S.-c., Cheng, J.-w., Chung, C.-y., Yan, Y. Tags: Clinical Research Articles Source Type: research