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Total 496 results found since Jan 2013.

Cerebral venous thrombosis in a breast cancer patient taking tamoxifen: Report of a case
Conclusion Clinicians should warn about the possibility of thromboembolic complications with tamoxifen.
Source: International Journal of Surgery Case Reports - November 29, 2014 Category: Surgery Source Type: research

HRT increases ovarian cancer risk by small amount
Conclusion This systematic review and meta-analysis showed that ovarian cancer risk was significantly increased in current HRT users, even in those with less than five years of HRT use (the average was three years). In ex-users, risks decreased the longer ago HRT use had stopped, but risks during the first few years after stopping remained significant. Furthermore, about a decade after stopping, long-duration hormone therapy use (average nine years of HRT use), there still seemed to be a small excess risk. The review has a few limitations, however. The main one is that the review was heavily influenced by just two of t...
Source: NHS News Feed - February 13, 2015 Category: Consumer Health News Tags: Cancer Medication Older people Source Type: news

Temozolomide in low-grade gliomas: living longer and better
Low-grade gliomas (LGGs) account for about a third of gliomas overall and 15% of all primary brain tumours. In adults, the majority of LGGs are WHO Grade II astrocytomas and oligodendrogliomas, which differ in molecular fingerprints and median survival, but share a propensity to malignant transformation after a number of years. Up to 90% of LGGs present with seizures and epilepsy may be the only symptom for many years, significantly impairing quality of life and impacting on social and professional functioning.1 In about 50% of cases, the epilepsy is refractory to antiepileptic drugs (AEDs) with a quarter of patients requi...
Source: Journal of Neurology, Neurosurgery and Psychiatry - March 13, 2015 Category: Neurosurgery Authors: Rees, J. Tags: Immunology (including allergy), Epilepsy and seizures, Neurooncology, Stroke, CNS cancer, Radiology, Surgical oncology Editorial commentaries Source Type: research

Cigarette warning labels may be more effective with imagery
Young adults are more likely to appreciate the dangers of smoking when warnings are presented in images as well as text, according to a new study. The labels used in the study emphasized negative consequences of smoking associated with lung cancer, heart disease and stroke, impotence, eye disease, neck, throat and mouth cancers, and vascular disease.
Source: ScienceDaily Headlines - April 7, 2015 Category: Science Source Type: news

Hormone therapy and venous thromboembolism among postmenopausal women
Despite a decrease in postmenopausal hormone therapy (HT) use during the last decade, many women are still prescribed this treatment which remains the most effective to counteract climacteric symptoms. However, HT increases the risk of breast cancer, stroke and venous thromboembolism (VTE) which represents the major harmful effect of short-term duration use. Nevertheless, this benefit/risk ratio has been established among women using oral estrogens alone or combined with a specific progestogen and cannot be necessary extrapolated to other HT.
Source: Maturitas - April 21, 2015 Category: Primary Care Authors: Marianne Canonico Tags: INV32 Source Type: research

Smoking Rates Are Down, But A Different Type Of Tobacco Use Is On The Rise
First, the good news: Smoking rates are down significantly in 26 states. The bad news? The use of smokeless tobacco (also known as dip, snuff or chew) is up in four states, while using both cigarettes and smokeless tobacco is up significantly in five states. “Although overall cigarette smoking prevalence has declined significantly in recent years in many states, the overall use of smokeless tobacco and concurrent cigarette and smokeless tobacco has remained unchanged in most states and increased in some states,” summed up researchers for the Centers for Disease Control, which published the data in their weekly Morbid...
Source: Science - The Huffington Post - May 22, 2015 Category: Science Source Type: news

Abstract SY02-04: Risk factors associated with cancer, type 2 diabetes, and cardiovascular disease in the multiethnic cohort: Comparisons across ethnic groups
Many chronic diseases common in the United States, such as cancer, type II diabetes and cardiovascular disease, share many lifestyle risk factors, such as tobacco use, obesity, diet, and lack of physical activity. These factors likely act upon disease through common pathways, such as inflammation and immune suppression. Examining the association of these risk factors with chronic conditions within a cohort could provide insights into their roles in the etiology of cancer and disease in general.The Multiethnic Cohort (MEC) is a prospective study that enrolled over 215,000 individuals in Hawaii and California from 1993 to 19...
Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: Wilkens, L. Tags: Epidemiology Source Type: research

Prevalence of menopausal symptoms among mid-life women: findings from electronic medical records
Conclusion: Our findings provide recent data on the types of menopausal symptoms experienced by mid-life women prescribed HT. Electronic medical records may be a rich source of data for future studies of menopausal symptoms in this population.
Source: BMC Women's Health - August 13, 2015 Category: OBGYN Authors: Matthew SussmanJeffrey TrocioCraig BestSebastian MirkinAndrew BushmakinRobert YoodMark FriedmanJoseph MenzinMichael Louie Source Type: research

Reminder: Smoking Hookah For An Hour Is Like Smoking 100 Cigarettes
You hopefully wouldn't smoke 100 cigarettes in 60 minutes -- that's five entire packs of so-called cancer sticks.  If you casually dabble with hookah, however, you might not bat an eye at an hour-long smoking session. New research shows lots of young people don't know that 100 cigarettes and an hour of hookah are about equal in terms of the amount of smoke inhaled -- and therefore in the damage they can cause to a person's health, including increased risk for heart disease, cancers, stroke, blood clots and death, to name a few. A 2005 report by the World Health Organization found that hookah smokers typ...
Source: Healthy Living - The Huffington Post - August 25, 2015 Category: Consumer Health News Source Type: news

Gambia: Drug Addiction and Health
[The Point] People who suffer from addiction often have one or more accompanying medical issues, which may include lung or cardiovascular disease, stroke, cancer, and mental disorders. Imaging scans, chest X-rays, and blood tests show the damaging effects of long-term drug abuse throughout the body. For example, research has shown that tobacco smoke causes cancer of the mouth, throat, larynx, blood, lungs, stomach, pancreas, kidney, bladder, and cervix.19 In addition, some drugs of abuse, such as inhalants, are toxic
Source: AllAfrica News: Health and Medicine - September 1, 2015 Category: African Health Source Type: news

Atrial fibrillation, CHA2DS2-VASc score, antithrombotics and risk of non-traffic-, non-cancer-related bone fractures: A population-based cohort study.
CONCLUSION: Patients with AF are more vulnerable to non-traffic-, non-cancer-related bone fractures especially when with specified characteristics. For those with higher CHA2DS2-VASc scores, the use of anticoagulant but not antiplatelet agents could be associated with lower risk of such events. PMID: 26493861 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - October 19, 2015 Category: Internal Medicine Authors: Lai HC, Chien WC, Chung CH, Lee WL, Wu TJ, Wang KY, Liu CN, Liu TJ Tags: Eur J Intern Med Source Type: research

Pathobiology of tobacco smoking and neurovascular disorders: untied strings and alternative products
Tobacco smoke (TS) is the leading cause of preventable deaths worldwide. In addition to a host of well characterized diseases including chronic obstructive pulmonary disease, oral and peripheral cancers and cardiovascular complications, epidemiological evidence suggests that chronic smokers are at equal risk to develop neurological and neurovascular complications such as multiple sclerosis, Alzheimer’s disease, stroke, vascular dementia and small vessel ischemic disease (SVID). Unfortunately, few direct neurotoxicology studies of tobacco smoking and its pathogenic pathways have been produced so far. A major link between ...
Source: Cerebrospinal Fluid Research - October 31, 2015 Category: Neurology Authors: Pooja NaikLuca Cucullo Source Type: research

Abstract PR04: Functional mobility disparities in older African American women with cancer in a multisite lay navigation program in the Deep South
Conclusions: AA oncogeriatric females have a greater number of high risk diseases and functional mobility limitations that affect their health, compared to Caucasians. By identifying functional mobility limitations early, proactive interventions can be implemented, monitored, and adjusted to modify or resolve mobility problems that can lead to disability and health disparities in oncogeriatric females. LNs can effectively use the DT to identify functional mobility problems and empower female oncogeriatrics to resolve them; improving health and decreasing health disparities. Data will be used to continue expanding the knowl...
Source: Cancer Epidemiology Biomarkers and Prevention - September 30, 2015 Category: Cancer & Oncology Authors: Taylor, R., Acemgil, A., Meneses, K., Rocque, G., Pisu, M., Wang, X., Demark-Wahnefried, W., Partridge, E. Tags: Community-Based Interventions: Oral Presentations - Proffered Abstracts Source Type: research