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Condition: Hypertension
Procedure: Transplants

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Total 198 results found since Jan 2013.

E-260 Bilateral cerebral arteriovenous shunting through pial and perforating vessels with multiple strokes and intraparenchymal hemorrhages in a patient with hepatopulmonary syndrome
This study presents a unique case of a 54-year-old male patient with a history of stroke, liver cirrhosis, portal vein thrombosis, hypertension, diabetes, and bladder cancer, who experienced multiple episodes of intracranial hemorrhages, stroke and worsening confusion over the past five years. The patient‘s clinical presentation raised suspicion for an underlying occult vasculopathy. Digital subtraction angiography (DSA) revealed multiple curvilinear, irregular, bilateral pial vessels with early high-flow arteriovenous shunting, consistent with vascular shunting that is associated with liver cirrhosis. The patient&ls...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Aljeradat, B., Koneru, M., Oliveira, R., Shaikh, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

McConnell ’ s Bid to Downplay Freezes Undermined by History of Politicians Lying About Their Health
After Senate Minority Leader Mitch McConnell froze during a press conference this month, the Kentucky Republican’s second such episode this summer, his office released a note from the Capitol physician intended to calm those worried about his ability to continue at his job. Dr. Brian Monahan told McConnell in the letter that there was “no evidence that you have a seizure disorder or that you experienced a stroke, TIA or movement disorder such as Parkinson’s disease.” Monahan suggested the episodes may be related to the Leader’s concussion in March or to dehydration.  [time-brightcove n...
Source: TIME: Health - September 11, 2023 Category: Consumer Health News Authors: Mini Racker Tags: Uncategorized Congress Source Type: news

Cardiovascular risk in women attending primary care centres: baseline data of the EVA study
Conclusions Four in 10 women attending primary care centres had a high or very high cardiovascular risk. Percentages of classic cardiovascular risk factors were higher in HT than in NHT and increased significantly with age. The most commonly used drugs were renin–angiotensin system blockers and diuretics.
Source: Nephrology Dialysis Transplantation - December 20, 2012 Category: Urology & Nephrology Authors: Fernandez-Vega, F., Prieto-Diaz, M. A., Redondo, M., Garcia-Norro, F. J., Suliman, N., Diaz, A., Vidal, C., Rodriguez, J. M., Montero, F. J., Gonzalez, M. B., Suarez, S., Garcia, J. J., Redondo, P. Tags: Original articles Source Type: research

A Clinical Phenotype of Adverse Response to Biventricular Pacing: A Case Series
ConclusionsA phenotype of adverse response to biventricular pacing is characterized by relatively narrow QRS duration, RV dysfunction, and pulmonary hypertension. Clinical decline is rapid and associated with the development of RBBB‐type morphology, worsening of pulmonary hemodynamics, and RV dysfunction with biventricular pacing.
Source: Pacing and Clinical Electrophysiology : PACE - January 10, 2013 Category: Cardiology Authors: HOONG SERN LIM Tags: Original Article Source Type: research

Structural Renal Changes in Obesity and Diabetes
Summary: Overweight, obesity, and associated diseases represent an emerging problem, not only in Western countries but also in the developing world. They are now characterized as epidemic diseases. Obesity is particularly serious because its incidence in children and adolescents increased dramatically: it is estimated that in the United States every eighth adolescent suffers from obesity, which in the long run may reduce life expectancy in the population. Apart from cardiovascular disease (ie, blood pressure, stroke, and coronary heart disease), kidney diseases also have been shown to be associated with obesity. Epidemiol...
Source: Seminars in Nephrology - January 1, 2013 Category: Urology & Nephrology Authors: Kerstin Amann, Kerstin Benz Tags: Gunter Wolf, MD, MHBA Source Type: research

Sympathetic Neural and Hemodynamic Responses to Upright Tilt in Patients With Pulsatile and Nonpulsatile Left Ventricular Assist Devices Original Articles
Conclusions— Heart failure patients with continuous, nonpulsatile LVADs have marked sympathetic activation, which is likely due, at least in part, to baroreceptor unloading. We speculate that such chronic sympathetic activation may contribute to, or worsen end-organ diseases, and reduce the possibility of ventricular recovery. Strategies to provide some degree of arterial pulsatility, even in continuous flow LVADs may be necessary to achieve optimal outcomes in these patients.
Source: Circulation: Heart Failure - March 19, 2013 Category: Cardiology Authors: Markham, D. W., Fu, Q., Palmer, M. D., Drazner, M. H., Meyer, D. M., Bethea, B. T., Hastings, J. L., Fujimoto, N., Shibata, S., Levine, B. D. Tags: Congestive, CV surgery: transplantation, ventricular assistance, cardiomyopathy Original Articles Source Type: research

Fabry nephropathy: indications for screening and guidance for diagnosis and treatment by the European Renal Best Practice
Fabry disease (FD) is an X-linked disorder of glycosphingolipid catabolism resulting in the accumulation of glycolipids including globotriaosylceramide in cells of various tissues resulting in end-organ manifestations. Initially, FD is typically characterized by angiokeratoma and recurrent episodes of neuropathic pain in the extremities occurring during childhood or adolescence. Most affected patients also exhibit a decreased ability to sweat. Later in life, FD results in left ventricular hypertrophy, proteinuria, renal failure and stroke. These later disease manifestations are non-specific and also common in diabetes, hyp...
Source: Nephrology Dialysis Transplantation - March 5, 2013 Category: Urology & Nephrology Authors: Terryn, W., Cochat, P., Froissart, R., Ortiz, A., Pirson, Y., Poppe, B., Serra, A., Van Biesen, W., Vanholder, R., Wanner, C. Tags: NDT PERSPECTIVES Source Type: research

Long-Term Outcome and Evaluation of Organ Function in Pediatric Patients Undergoing Haploidentical and Matched Related Hematopoietic Cell Transplantation for Sickle Cell Disease
We report the long-term outcomes of 22 pediatric patients who underwent related donor HSCT for SCD at St. Jude Children's Research Hospital, either a myeloablative sibling MRD HSCT (n = 14) or reduced-intensity parental haploidentical donor HSCT (n = 8). The median patient age was 11.0 ± 3.9 years in the MRD graft recipients and 9.0 ± 5.0 years in the haploidentical donor graft recipients. The median follow-up was 9.0 ± 2.3 years, with an overall survival (OS) of 93% and a recurrence/graft failure rate of 0%, for the MRD cohort and 7.4 ± 2.4 years, with an OS of 75%, disease-free survival of 38%, and disease recurren...
Source: Biology of Blood and Marrow Transplantation - February 18, 2013 Category: Hematology Authors: Mari H. Dallas, Brandon Triplett, David R. Shook, Christine Hartford, Ashok Srinivasan, Joseph Laver, Russell Ware, Wing Leung Tags: Clinical Research Source Type: research

Cardiovascular Risk Factors and Events in Pancreas-Kidney Transplants
Abstract: Cardiovascular and cerebrovascular disease (CCVD) are major causes of morbidity and mortality among patients with diabetes. Strict control of treatable risk factors that contribute to atherosclerosis is important to reduce the risk of stroke, myocardial infarction, and peripheral arterial disease. Simultaneous pancreas-kidney transplantation (SPKT) may significantly improve these risk factors in patients with type 1 diabetes. We studied 103 SPKT from our center with both organs functioning for metabolic and hypertensive control; body mass index (BMI); immunosuppression; and CCVD events. The 53 females/50 males s...
Source: Transplantation Proceedings - April 1, 2013 Category: Transplant Surgery Authors: L. Martins, I. Fonseca, L. Dias, J. Malheiro, A. Rocha, P. Azevedo, H. Silva, R. Almeida, A.C. Henriques, J. Davide, A. Cabrita Tags: Renal Transplantation Source Type: research

Hypertension in CKD
Conclusions: Compared to pre-HD blood pressure, home blood pressure seemed to be better in predicting mortality and cardiovascular outcomes.
Source: Nephrology Dialysis Transplantation - May 10, 2013 Category: Urology & Nephrology Authors: Iseki, K., Arima, H., Poulikakos, D., Banerjee, D., Malik, M. Tags: Abstracts Source Type: research

Chronic obstructive pulmonary disease.
Abstract The global prevalence of physiologically defined chronic obstructive pulmonary disease (COPD) in adults aged >40 yr is approximately 9-10 per cent. Recently, the Indian Study on Epidemiology of Asthma, Respiratory Symptoms and Chronic Bronchitis in Adults had shown that the overall prevalence of chronic bronchitis in adults >35 yr is 3.49 per cent. The development of COPD is multifactorial and the risk factors of COPD include genetic and environmental factors. Pathological changes in COPD are observed in central airways, small airways and alveolar space. The proposed pathogenesis of COPD includes pr...
Source: The Indian Journal of Medical Research - February 1, 2013 Category: Biomedical Science Authors: Vijayan VK Tags: Indian J Med Res Source Type: research

Prognostic Significance of Cardiac Magnetic Resonance Imaging in Children With Pulmonary Hypertension Original Articles
Conclusions— Cardiac MR measures correlate with clinical status and prognosis in children with pulmonary hypertension. Cardiac MR is feasible and may be useful in clinical decision making in pediatric pulmonary hypertension.
Source: Circulation: Cardiovascular Imaging - May 21, 2013 Category: Radiology Authors: Moledina, S., Pandya, B., Bartsota, M., Mortensen, K. H., McMillan, M., Quyam, S., Taylor, A. M., Haworth, S. G., Schulze-Neick, I., Muthurangu, V. Tags: Pulmonary circulation and disease, CT and MRI Original Articles Source Type: research

Kidney disease and cognitive function.
Abstract We provide a brief review of research on chronic kidney disease and cognitive performance, including dementia. We touch briefly on the literature relating end-stage-renal disease to cognitive function, but focus on studies of modest and moderate forms of chronic kidney disease (CKD) that precede dialysis and transplantation. We summarize previous reviews dealing with case control studies of patients but more fully examine community-based studies with large samples and necessary controls for demographic risk factors, cardiovascular variables, and other confounds such as depression. In addition we suggest p...
Source: Contributions to Nephrology - May 26, 2013 Category: Urology & Nephrology Authors: Elias MF, Dore GA, Davey A Tags: Contrib Nephrol Source Type: research

Effect of Reduced Sympathetic Hyperactivity on Cardiovascular Risk Factors in Kidney Transplantation Patients
Abstract: Background: Hyperactivity of the sympathetic nervous system caused by chronic kidney disease has detrimental effects on hypertension and cardiovascular morbidity. Kidney transplantation does not ameliorate sympathetic nerve overactivity; however, bilateral nephrectomy eliminates it. The aim of the study was to evaluate the effect of bilateral nephrectomy on risk factors for cardiovascular morbidity and mortality in long-term follow-up. Material and Methods: We studied 24 kidney recipients aged 44 ± 13 years who had undergone native bilateral nephrectomy. The control group included 17 recipients with preserve...
Source: Transplantation Proceedings - May 1, 2013 Category: Transplant Surgery Authors: M. Boratyńska, A.M. Zoń, M. Obremska, K. Pocza̧tek, M. Protasiewicz, M. Magott, M. Klinger Tags: Renal Transplantation Source Type: research

Effects of angiotensin receptor blockade (ARB) on mortality and cardiovascular outcomes in patients with long-term haemodialysis: a randomized controlled trial
Conclusions BP-lowering treatment with an ARB did not significantly lower the risks of major cardiovascular events or death among patients with hypertension on chronic HD. (Cochrane Renal Group Prospective Trial Register number CRG010600030).
Source: Nephrology Dialysis Transplantation - June 18, 2013 Category: Urology & Nephrology Authors: Iseki, K., Arima, H., Kohagura, K., Komiya, I., Ueda, S., Tokuyama, K., Shiohira, Y., Uehara, H., Toma, S., on behalf of the Olmesartan Clinical Trial in Okinawan Patients Under OKIDS (OCTOPUS) Group, Tomiyama, Arima, Chinen, Tokashiki, Hirano-Nakasone, N Tags: Intra- and Extracorporeal Treatment of Kidney Failure Source Type: research