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Total 4516 results found since Jan 2013.

The Racial Gap in U.S. Stroke Deaths Got Worse During the Pandemic
NEW YORK — The longstanding racial gap in U.S. stroke death rates widened dramatically during the COVID-19 pandemic, government researchers said Thursday. Stroke death rates increased for both Black and white adults in 2020 and 2021, according to the Centers for Disease Control and Prevention study. But the difference between the two groups grew about 22%, compared with the five years before the pandemic. “Any health inequity that existed before seems to have been made larger during the pandemic,” said Dr. Bart Demaerschalk, a stroke researcher at the Mayo Clinic in Phoenix who was not involved in the new...
Source: TIME: Health - April 20, 2023 Category: Consumer Health News Authors: Mike Stobbe/AP Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

Sex differences in outcomes after stroke among patients with low total cholesterol levels: a large hospital-based prospective study
ConclusionsThese findings suggest that patients (both men and women) with atherothrombotic infarction who have low TC levels would not benefit from receiving statin treatment. Therefore, it is crucial to explore the impact of statin treatment on outcomes in Asian patients, especially Chinese patients with atherothrombotic and low TC levels, in order to improve outcomes after stroke and reduce the disease burden.
Source: Biology of Sex Differences - November 23, 2016 Category: Biology Source Type: research

Urban-rural differences in risk factors for ischemic stroke in northern China
This study aims to investigate urban-rural differences in characteristics and risk factors of ischemic stroke in northern China. The present cross-sectional study was based on the High-risk Population Screening and Intervention Project for Stroke. The cluster sampling method was used to select urban and rural screening sites in northern China. By collecting information and screening the data, patients with ischemic stroke were obtained and a control group with similar gender, age, and regional distribution was selected among the nonischemic stroke patients. Then, the demographic and risk factors of patients with ischemic ...
Source: Medicine - May 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Stroke Epidemiology in Oceania: A Review
Conclusions: Stroke is a major healthcare problem in Oceania. Variations in stroke epidemiology are found between countries in Oceania. Data are lacking in some; more research into the burden of stroke in Oceania is needed. With the expected increase in life expectancy and vascular risk factors, the burden of stroke in Oceania will likely rise. Some of the disparities in stroke burden may be addressed by great investment in healthcare.Neuroepidemiology
Source: Neuroepidemiology - February 18, 2021 Category: Epidemiology Source Type: research

Stroke incidence and outcome disparity in Rural regions of Southern West Virginia
Conclusions: Stroke incidence and mortality were found to be higher than expected in many areas of rural West Virginia. The higher stroke risk populations correlate with area that may be impacted by socioeconomic factors and limited access to primary care. These high-risk areas may therefore benefit from investments in infrastructure, patient education, and unrestricted primary care.
Source: Journal of Emergencies, Trauma and Shock - December 24, 2021 Category: Emergency Medicine Authors: Frank Harrison Annie Mark C Bates Muhammad Khan Salman Zahid Syed Imran Shah Aravinda Nanjundappa Joshua R Wyner Elise Anderson Ali Farooq Megan Wood Abhiram Challa Source Type: research

Sleep duration and history of stroke among adults from the USA.
Abstract Although short sleep duration is related to chronic conditions, such as hypertension, diabetes and obesity, the association with stroke is less well known. Using 2006-2011 National Health Interview Surveys, we assessed the association between self-reported duration of sleep and prevalence of stroke stratifying by age and sex. Of the 154 599 participants aged 18 years or older, 29.2%, 61.8% and 9.0% reported they sleep ≤6, 7-8 and ≥9 h per day, respectively. Corresponding age-standardized prevalence of stroke were 2.78%, 1.99% and 5.21% (P < 0.001). Logistic regression models showed a higher pr...
Source: Journal of Sleep Research - May 12, 2014 Category: Sleep Medicine Authors: Fang J, Wheaton AG, Ayala C Tags: J Sleep Res Source Type: research

Differences in Ischaemic and Haemorrhagic Strokes in Sri Lanka: 7-year data from the Ragama Stroke Registry (P1.092)
CONCLUSIONS:Clinical and risk factor profiles were different between ICH and IS patients. Stroke severity and functional disability were higher among ICH patients. Study Supported by:Ragama Stroke Registry has been partly supported by research grants from the University of Kelaniya and Research Institute, International Medical Centre of Japan.Disclosure: Dr. Ranawaka has nothing to disclose. Dr. Peiris has nothing to disclose. Dr. Thirumavalavan has nothing to disclose. Dr. Premawansa has nothing to disclose. Dr. Kasthuriratne has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ranawaka, U., Peiris, A., Thirumavalavan, K., Premawansa, G., Kasthuriratne, A. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Sex differences in long-term outcomes among acute ischemic stroke patients with diabetes in China
Conclusions These findings suggest that it is crucial to establish the individual scheme of therapy for every patient by different risk factors of stroke, strengthen the rehabilitation of stroke, and carry on the health education early for the secondary prevention of stroke in patients with diabetes mellitus (DM).
Source: Biology of Sex Differences - December 4, 2015 Category: Biology Source Type: research

Highly Prevalent Hyperuricaemia is Associated with Adverse Clinical Outcomes Among Ghanaian Stroke Patients: An Observational Prospective Study.
CONCLUSIONS: Hyperuricaemia is highly frequent and associated with adverse functional outcomes among Ghanaian stroke patients. Further studies are warranted to determine whether reducing SUA levels after a stroke would be beneficial within our setting. PMID: 26693192 [PubMed - in process]
Source: Ghana Medical Journal - December 24, 2015 Category: African Health Tags: Ghana Med J Source Type: research

Stroke among African‐Caribbean women: lay beliefs of risks and causes
ConclusionAlternative explanations of the causes of stroke that include witchcraft, or wishing someone wrong suggests a lack of perceived control over stroke. This may suggest a focus on less visible risk factors such as hypertension, familial history or diabetes and will need inclusion in health promotion materials. Lay beliefs such as witchcraft can co‐exist amicably alongside modern medicine, as long as they do not hinder access to medication, treatment or risk factor management of stroke. Relevance to clinical practiceThe results demonstrated that nursing care and health promotion materials should emphasise on obesit...
Source: Journal of Clinical Nursing - January 28, 2016 Category: Nursing Authors: Calvin Moorley, Sharon Cahill, Nova Corcoran Tags: Original Article Source Type: research

Sex differences in neuroinflammation and neuroprotection in ischemic stroke
Stroke is not only a leading cause of mortality and morbidity worldwide it also disproportionally affects women. There are currently over 500,000 more women stroke survivors in the US than men, and elderly women bear the brunt of stroke‐related disability. Stroke has dropped to the fifth leading cause of death in men, but remains the third in women. This review discusses sex differences in common stroke risk factors, the efficacy of stroke prevention therapies, acute treatment responses, and post‐stroke recovery in clinical populations. Women have an increased lifetime risk of stroke compared to men, largely due to a s...
Source: Journal of Neuroscience Research - November 6, 2016 Category: Neuroscience Authors: Monica S. Spychala, Pedram Honarpisheh, Louise D. McCullough Tags: Review Source Type: research

Heat Shock Protein A12A Encodes a Novel Prosurvival Pathway during Ischaemic Stroke.
This study investigated the effects of HSPA12A on ischaemic stroke in mice. Ischaemic stroke was induced by left middle cerebral artery occlusion for 1 h followed by blood reperfusion. We observed that HSPA12A was highly expressed in brain neurons, and neuronal HSPA12A expression was downregulated by ischaemic stroke and stroke-associated risk factors (aging, obesity and hyperglycaemia). To investigate the functional requirement of HSPA12A in protecting ischaemic brain injury, HSPA12A knockout mice (Hspa12a-/-) were generated. Hspa12a-/- mice exhibited an enlarged infarct volume and aggravated neurological deficits compare...
Source: Biochimica et Biophysica Acta - March 9, 2018 Category: Biochemistry Authors: Mao Y, Kong Q, Li R, Zhang X, Gui Y, Li Y, Li C, Zhao Y, Liu L, Ding Z Tags: Biochim Biophys Acta Source Type: research

Stroke incidence is highest in women and non-Hispanic blacks living with HIV in the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort
Conclusion: Women and non-Hispanic Blacks living with HIV had the highest incidence rates of stroke/TIA. A concerted effort must be made to include PLWH from these at-risk groups in observational and interventional studies aimed at understanding stroke mechanisms and reducing stroke risk in HIV infection. Strategies to modify stroke risk in PLWH should employ a multipronged approach targeting vascular risk factors and engaging and retaining patients in HIV care.
Source: AIDS - May 11, 2018 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Obesity-induced type 2 diabetes impairs neurological recovery after stroke in correlation with decreased neurogenesis and persistent atrophy of parvalbumin-positive interneurons
Type 2 diabetes (T2D) hampers stroke recovery though largely undetermined mechanisms. Few preclinical studies have investigated the effect of genetic/toxin-induced diabetes on long-term stroke recovery. However, the effects of obesity-induced T2D are mostly unknown. We aimed to investigate whether obesity-induced T2D worsens long-term stroke recovery through the impairment of brain's self-repair mechanisms - stroke-induced neurogenesis and parvalbumin (PV)+ interneurons-mediated neuroplasticity. To mimic obesity-induced T2D in the middle-age, C57bl/6j mice were fed 12 months with high-fat diet and subjected to transient mi...
Source: Clinical Science - June 23, 2019 Category: Biomedical Science Authors: Pintana, H., Lietzau, G., Augestad, I. L., Chiazza, F., Nystrom, T., Patrone, C., Darsalia, V. Tags: PublishAheadOfPrint Source Type: research

A nonlinear association between resting heart rate and ischemic stroke among community elderly hypertensive patients.
Conclusions: In Chinese elderly hypertensive patients, elevated resting heart rate was an independent predictor of ischemic stroke, and the optimal resting heart rate was around 70bpm. PMID: 31829063 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - December 13, 2019 Category: Internal Medicine Tags: Postgrad Med Source Type: research