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Source: International Journal of Cardiology
Condition: Heart Failure
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Total 126 results found since Jan 2013.
Acute kidney injury and long-term risk of stroke after coronary artery bypass surgery
This study investigated the association between AKI and long-term risk of stroke.Methods and results: 50,244 patients who underwent coronary artery bypass grafting (CABG) in Sweden between 2000 and 2008 were identified from the SWEDEHEART registry. After exclusions 23,584 patients without prior stroke who underwent elective, primary, isolated, CABG were included. AKI was categorized according to absolute increases in postoperative creatinine values compared with preoperative values: stage 1, 0.3–0.5mg/dL (26–44μmol/L); stage 2, 0.5–1.0mg/dL (44–88μmol/L); and stage 3,>1.0mg/dL (≥88μmol/L). Cox proportional haz...
Source: International Journal of Cardiology - September 9, 2013 Category: Cardiology Authors: Martin J. Holzmann, Linda Rydén, Ulrik Sartipy Tags: Original Articles Source Type: research
Warfarin may reduce risk of ischemic stroke by preventing atrial fibrillation for patients with heart failure and sinus rhythm
As compared with the general population, patients with reduced ejection fraction who are in sinus rhythm are observed with a higher risk for ischemic stroke. This relationship is caused by left ventricular stasis, a systemic hypercoagulable state, and endocardial dysfunction in a situation of impaired left ventricular systolic function . Therefore, the issue whether antithrombotic agents especially aspirin or warfarin could successfully prevent stroke for patients with heart failure and sinus rhythm has been tested in a series of clinical trials. The former two trials (the Warfarin/Aspirin Study in Heart Failure (WASH) tri...
Source: International Journal of Cardiology - July 16, 2012 Category: Cardiology Authors: Gen-Min Lin, Yi-Hwei Li, Lamin .E.S. Jaiteh, Chih-Lu Han Tags: Letters to the Editor Source Type: research
New oral anticoagulants for stroke prevention in left ventricular hypertrabeculation/noncompaction?
Left ventricular hypertrabeculation/noncompaction (LVHT) is a cardiac abnormality of unknown etiology, associated with neuromuscular disorders, and an increased risk of heart failure, arrhythmias, and stroke or embolism (S/E) . We have shown that in 22 of 144 LVHT patients (15%) stroke (n=21) or peripheral embolism (n=1) had occurred. S/E etiology was either cardioembolic (n=14), atherosclerotic (n=5) or undetermined (n=3). Among the patients with cardioembolic S/E, 13/14 had either atrial fibrillation (AF) or systolic dysfunction . In a nested case–control study of patients with severe systolic dysfunction the stroke in...
Source: International Journal of Cardiology - April 19, 2013 Category: Cardiology Authors: Claudia Stöllberger, Josef Finsterer Tags: Letters to the Editor Source Type: research
Myocardial fibrosis in stroke survivors
Stroke survivors are most likely to die of cardiac death, yet few undergo comprehensive cardiac assessment to look for reversible causes. Myocardial fibrosis (MF) is not only the hallmark of cardiomyopathy, but also a substrate for sudden cardiac death, ventricular tachyarrhythmia and heart failure. Procollagen carboxyl-terminal telopeptide (PICP) was found to be a marker of MF. The relationship between PICP and cardiac abnormalities in stroke survivors is unknown. We recently showed that MF in stroke survivors can be treated by spironolactone and amiloride in a randomised placebo-controlled cross-over study with reduction...
Source: International Journal of Cardiology - March 19, 2015 Category: Cardiology Authors: K. Wong, S. Sze, S. Wong, S. McSwiggan, V. Allgar, R. MacWalter, A.D. Struthers Tags: Letter to editor Source Type: research
Increased arterial stiffness and haemorrhagic transformation in ischaemic stroke after thrombolysis: A new marker of risk for cerebrovascular events and complications
Essential hypertension is the most frequent cardiovascular risk factor in the general population, and its prevalence is even higher in specific subsets of high-risk individuals, such as elderly, patients with diabetes, coronary artery disease or stroke [1]. In view of the large prevalence and growing incidence, as well as in view of the strong and independent correlation between high blood pressure (BP) levels and increased risk of major cardiovascular and cerebrovascular complications, mostly including myocardial infarction, stroke, congestive heart failure and cardiovascular death [2], several studies have addressed the ...
Source: International Journal of Cardiology - July 23, 2017 Category: Cardiology Authors: Giuliano Tocci, Vivianne Presta Tags: Editorial Source Type: research
Could the CHA2DS2-VASc schema help stratify risk of ischemic stroke for individual patients with congestive heart failure?
We read the article “Risk of stroke in congestive heart failure with and without atrial fibrillation” by Kang et al. [1] interestingly, which has great clinical significance in prevention of ischemic stroke during the management of congestive heart failure (CHF) patients. CHF has been shown to be associated with2 t o 3 times higher risk of stroke [2,3], also known as cardioembolism that is due to thrombus formation caused by atrial fibrillation (AF) or stagnation of blood in the left ventricle [4,5].
Source: International Journal of Cardiology - March 3, 2018 Category: Cardiology Authors: Jing Bai, Deliang Shen, Bo Wang, Qing Han, Peiwen Wang, Jinying Zhang Tags: Letter to the Editor Source Type: research
Stroke prevention in atrial fibrillation: State of the art
Stroke prevention is the cornerstone of the management of patients with atrial fibrillation (AF). Individual stroke risk stratification is generally the first step of deciding whether oral anticoagulation (OAC) will benefit patients with AF. Given that existing approaches to the prediction of ‘high risk’ subjects are of limited value, the initial focus should be the identification of ‘low-risk’ patients who do not need antithrombotic therapy. For this, the CHA2DS2-VASc score (congestive heart failure, hypertension, age ≥ 75 [2 points], diabetes mellitus, previous stroke/tra nsient ischemic attack [2 points], ...
Source: International Journal of Cardiology - September 19, 2018 Category: Cardiology Authors: Yan-Guang Li, Gregory Y.H. Lip Tags: Review Source Type: research
Assessment of stroke risk in Middle Eastern patients with atrial fibrillation: The Gulf SAFE registry
Limited data are available on the epidemiology of AF in non-European, non-Caucasian populations . The aim of the present study was to present the thromboembolic risk profile and for the first time, to validate the performance of the CHADS2 (congestive heart failure, hypertension, age ≥75years, diabetes, stroke/TIA doubled) and CHA2DS2-VASc (congestive heart failure, hypertension, age ≥75years doubled, diabetes, stroke/TIA doubled, vascular disease, age 65–74, sex category [female]) scores in a Middle Eastern population.
Source: International Journal of Cardiology - March 7, 2013 Category: Cardiology Authors: S. Apostolakis, M. Zubaid, W.A. Rashed, A.A. Alsheikh-Ali, W. Almahmeed, A. Shehab, K. Sulaiman, A. AlQudaimi, N. Asaad, H. Amin, D.A. Lane, G.Y.H. Lip, On behalf of the Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) Investigators Tags: Letters to the Editor Source Type: research
Digoxin use is associated with increased risk of stroke in patients with non-valvular atrial fibrillation — a nationwide population-based cohort study
Atrial fibrillation (AF) is associated with increased risk of morbidity and mortality. Digoxin is often used as a rate control agent in AF patients, particularly in those with systolic heart failure. Although digoxin use in AF patients can reduce heart failure symptoms, increase exercise capacity and decrease hospitalizations , unfavorable effects on long-term outcomes have been reported . In the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study, a post-hoc analysis showed a higher rate of mortality in patients treated with digitalis medication . A study of the “Registry of Information and K...
Source: International Journal of Cardiology - September 23, 2013 Category: Cardiology Authors: Shih-Sheng Chang, Kuan-Cheng Chang, Yu-Chen Wang, Chih-Hsin Muo, Pei-Ying Pai, Chi-Bin Chang, Chi-Yuan Li, Fung-Chang Sung Tags: Online Letters to the Editor Source Type: research
Simultaneous onset of myocardial infarction and ischemic stroke in a patient with atrial fibrillation: Multiple territory injury revealed on angiography and magnetic resonance
An 84-year-old man with a history of hypertension and paroxysmal atrial fibrillation (AF) who received no anticoagulant drugs experienced acute chest pain and transient loss of consciousness. He was transferred to our emergency room. His initial electrocardiogram showed sinus rhythm with ST-segment elevation in the I, aVL, and V1–V6 leads. His blood pressure was 158/92mmHg and his pulse was regular at 70beats per minute. A chest radiograph showed increased heart size and pulmonary vascular congestion. His troponin T level was elevated (more than 0.1ng/mL). He was diagnosed with ST-elevation myocardial infarction (MI) and...
Source: International Journal of Cardiology - February 4, 2014 Category: Cardiology Authors: Osamu Hashimoto, Kozo Sato, Yohei Numasawa, Joji Hosokawa, Masahiro Endo Tags: Online Letters to the Editor Source Type: research
Subclinical Atrial Fibrillation Preceding Cardioembolic Stroke in a Patient with Systolic Heart Failure
Atrial fibrillation and congestive heart failure are risk factors for cerebral infarction. The most commonly used estimates of stroke risk in patients with atrial fibrillation are cardiac failure, hypertension, age, diabetes mellitus, and stroke (CHADS2 score) [1–4]. Although atrial fibrillation may be recognized by the presence of symptoms, such as palpitations, some patients are occasionally asymptomatic [5–7]. The absence of symptoms results in a delayed diagnosis, and may lead to fatal thromboembolic events.
Source: International Journal of Cardiology - August 13, 2014 Category: Cardiology Authors: Kihei Yoneyama, Tomoo Harada, Hidemichi Ito, Makoto Takano, Maya Tsukahara, Yukio Sato, Masashi Uchida, Satoru Nishio, Yoshihiro J. Akashi Source Type: research
Subclinical atrial fibrillation preceding cardioembolic stroke in a patient with systolic heart failure
Atrial fibrillation and congestive heart failure are risk factors for cerebral infarction. The most commonly used estimates of stroke risk in patients with atrial fibrillation are cardiac failure, hypertension, age, diabetes mellitus, and stroke (CHADS2 score) [1–4]. Although atrial fibrillation may be recognized by the presence of symptoms, such as palpitations, some patients are occasionally asymptomatic [5–7]. The absence of symptoms results in a delayed diagnosis and may lead to fatal thromboembolic events.
Source: International Journal of Cardiology - August 13, 2014 Category: Cardiology Authors: Kihei Yoneyama, Tomoo Harada, Hidemichi Ito, Makoto Takano, Maya Tsukahara, Yukio Sato, Masashi Uchida, Satoru Nishio, Yoshihiro J. Akashi Tags: Letter to the Editor Source Type: research
Risk of stroke in congestive heart failure with and without atrial fibrillation
This study estimated the risk of stroke and thromboembolism for patients with congestive heart failure (CHF) in the context of the general population, especially compared to those with atrial fibrillation (AF).
Source: International Journal of Cardiology - July 20, 2017 Category: Cardiology Authors: Si-Hyuck Kang, Joonghee Kim, Jin Joo Park, Il-Young Oh, Chang-Hwan Yoon, Hee-Jun Kim, Kyuseok Kim, Dong-Ju Choi Source Type: research
Influence of preload and afterload on stroke volume response to low-dose dobutamine stress in patients with non-ischemic heart failure: A cardiac MR study
Abstract: Background: Lack of increase in left ventricular (LV) stroke volume (SV) during low-dose dobutamine stress (LDD) is attributed to exhausted cardiac contractile reserve in failing heart. However, the role of the afterload and preload in SV changes is underestimated. The aim of the study was to investigate the effects of LDD on preload reserve and afterload in patients with non-ischemic heart failure.Methods: 58 patients (age 62years) underwent LDD (up to 20μg/kg/min) using cardiac magnetic resonance.Results: LV-SV increased by 27% in 24 patients (p
Source: International Journal of Cardiology - December 12, 2011 Category: Cardiology Authors: Alessandro Pingitore, Giovanni Donato Aquaro, Valentina Lorenzoni, Maddalena Gallotta, Daniele De Marchi, Sabrina Molinaro, Valentina Cospite, Claudio Passino, Michele Emdin, Massimo Lombardi, Vincenzo Lionetti, Antonio L'Abbate Tags: Original Articles Source Type: research
Recurrent stroke and myocardial infarction in a young woman with severe osteoporosis and hyperparathyroidism
We have taken great interest in the recently published article entitled “ Effect of calcium or vitamin D supplementation on vascular outcomes: A meta-analysis of randomized controlled trial” . Likewise, since parathormone (PTH) is a vasoactive peptide, we, herein, wish to draw attention to the fact that primary hyperparathyroidism (pHPT) can –as well– be in association with increased risk of cardiovascular diseases (i.e. myocardial infarction (MI), heart failure, thrombosis or cardioembolism, hypertension), stroke and osteoporosis . In this regard, we exemplify the clinical scenario of one of our pertinent patients.
Source: International Journal of Cardiology - January 21, 2014 Category: Cardiology Authors: Murat Kara, Levent Özçakar, Hatice Gözde Sümer, Timur Ekiz, Sibel Özbudak Demir, Ayşen Akıncı Tags: Online Letters to the Editor Source Type: research
