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Source: International Journal of Cardiology
Condition: Heart Failure

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Total 126 results found since Jan 2013.

Current presentation and management of 7148 patients with atrial fibrillation in cardiology and internal medicine hospital centers: The ATA AF study
Abstract: Background: Atrial fibrillation (AF) is associated with a high risk of stroke and mortality.Aims: To describe the difference in AF management of patients (pts) referred to Cardiology (CARD) or Internal Medicine (MED) units in Italy.Methods and results: From May to July 2010, 360 centers enrolled 7148 pts (54% in CARD and 46% in MED). Median age was 77years (IQR 70–83). Hypertension was the most prevalent associated condition, followed by hypercholesterolemia (28.9%), heart failure (27.7%) and diabetes (24.3%). MED pts were older, more frequently females and more often with comorbidities than CARD pts.In the 484...
Source: International Journal of Cardiology - August 13, 2012 Category: Cardiology Authors: Giuseppe Di Pasquale, Giovanni Mathieu, Aldo Pietro Maggioni, Gianna Fabbri, Donata Lucci, Giorgio Vescovo, Salvatore Pirelli, Francesco Chiarella, Marino Scherillo, Michele Massimo Gulizia, Gualberto Gussoni, Fabrizio Colombo, Domenico Panuccio, Carlo No Tags: Original Articles Source Type: research

A novel heart rate control model provides insights linking LF-HRV behavior to the open-loop gain
Conclusions: We are the first to demonstrate that LF-HRV may be dependent on the open-loop gain. Accordingly, reduced open-loop gain results in decreased LF-HRV, and vice versa. Our findings explain a well-known but unexplained observed phenomenon of reduced LF-HRV both in heart failure patients and in healthy subjects performing aerobic exercise. These findings have implications on how changes in LF-HRV can be interpreted physiologically, a necessary step towards the clinical utilization of LF-HRV.
Source: International Journal of Cardiology - October 12, 2012 Category: Cardiology Authors: Hila Dvir, Ben Zion Bobrovsky, Uri Gabbay Tags: Original Articles Source Type: research

Peripheral artery disease and outcomes after myocardial infarction: An individual-patient meta-analysis of 28,771 patients in CAPRICORN, EPEHESUS, OPTIMAAL and VALIANT
Abstract: Objectives: To examine the prevalence of peripheral artery disease (PAD) and the relationship between PAD and cardiovascular (CV) outcomes in subjects with left ventricular systolic dysfunction, heart failure or both after acute myocardial infarction (MI).Background: PAD is associated with poorer prognosis in patients with stable and unstable coronary heart disease but whether PAD is associated with worse outcomes following substantial acute MI is unknown.Methods: Univariate and multivariate Cox proportional hazards modelling was used to compare clinical outcomes in an individual-patient meta-analysis of 4 trials...
Source: International Journal of Cardiology - November 29, 2012 Category: Cardiology Authors: Sally C. Inglis, Judith Bebchuk, Sultan A. Al-Suhaim, Jessica Case, Marc A. Pfeffer, Scott D. Solomon, Yingxin (Rachel) Hou, Bertram Pitt, Henry J. Dargie, Ian Ford, John Kjekshus, Faiez Zannad, Kenneth Dickstein, John J.V. McMurray Tags: Original Articles Source Type: research

A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction
Conclusion: Anti-fibrotic therapy with FT011 in MI rats attenuated fibrosis and preserved systolic function.
Source: International Journal of Cardiology - December 10, 2012 Category: Cardiology Authors: Yuan Zhang, Maros Elsik, Amanda J. Edgley, Alison J. Cox, Andrew R. Kompa, Bing Wang, Christina Yan Ru Tan, Fay L. Khong, David I. Stapleton, Steven Zammit, Spencer J. Williams, Richard E. Gilbert, Henry Krum, Darren J. Kelly Tags: Original Articles Source Type: research

The role of diastolic filling in preserving left ventricular stroke volume — An MRI study
In this early part of the 21st century, many countries appear to be experiencing a ‘heart failure epidemic’, with prevalence rates worldwide in the order of 2% and increasing . But despite its significant global impact, there remains considerable debate over the most appropriate way to diagnose heart failure , especially that with a preserved ejection fraction (commonly known as HFPEF). HFPEF, defined as heart failure with a normal, or near normal, left ventricular ejection fraction (LVEF>50%), now comprises as much as 50–60% of those diagnosed with heart failure .
Source: International Journal of Cardiology - February 18, 2013 Category: Cardiology Authors: S. Offen, D. Celermajer, C. Semsarian, R. Puranik Tags: Letters to the Editor Source Type: research

The change in the atrial fibrillation type as a prognosis marker in a community study: Long-term data from AFBAR (Atrial Fibrillation in the BARbanza) study
Abstract: Background: The aim is to describe the prognosis role of the change in the atrial fibrillation (AF) type in an unselected population of patients with AF currently attending primary care in a single health-service area in Galicia, north-western Spain.Methods: AFBAR is a cohort study that was carried out by 35 primary care providers in 2008. Participants were followed up for a mean of 2.8±0.7years. 798 patients with the diagnosis of AF who presented at their clinics during a three-month period were recruited. Primary endpoint was mortality or hospital admission.Results: 778 patients (413 male) were analyzed; mean ...
Source: International Journal of Cardiology - March 1, 2013 Category: Cardiology Authors: Rafael Vidal-Perez, Fernando Otero-Raviña, Manuel Lado-López, Victorino Turrado-Turrado, Esperanza Rodríguez-Moldes, José L. Gómez-Vázquez, Concepción de Frutos-de Marcos, Paula de Blas-Abad, Ricardo Besada-Gesto, José Ramón Gonzalez-Juanatey, On Tags: Original Articles Source Type: research

Health-related quality of life associated with treatment adherence in patients with hypertension: A cross-sectional study
The objective of this study was to examine the relationship between adherence and HRQoL in a hypertensive population. Knowledge of any differences in HRQoL in this population may be helpful in the planning of therapeutic interventions that will ensure desirable HRQoL and not just the control of blood pressure. Knowledge of HRQoL in hypertensive patients and of the relationship between HRQoL and adherence, being a reliable determinant of cardiovascular disease (CVD) events, will be helpful in preventing or reducing the incidence of CVDs.
Source: International Journal of Cardiology - May 6, 2013 Category: Cardiology Authors: Sa'ed H. Zyoud, Samah W. Al-Jabi, Waleed M. Sweileh, Aysha H. Wildali, Hanan M. Saleem, Hayat A. Aysa, Mohammad A. Badwan, Rahmat Awang, Donald E. Morisky Tags: Letters to the Editor Source Type: research

Prediabetes is not an independent risk factor for incident heart failure, other cardiovascular events or mortality in older adults: Findings from a population-based cohort study
Conclusions: We found no evidence that prediabetes is an independent risk factor for incident HF, other cardiovascular events or mortality in community-dwelling older adults. These findings question the wisdom of routine screening for prediabetes in older adults and targeted interventions to prevent adverse outcomes in older adults with prediabetes.
Source: International Journal of Cardiology - June 3, 2013 Category: Cardiology Authors: Prakash Deedwania, Kanan Patel, Gregg C. Fonarow, Ravi V. Desai, Yan Zhang, Margaret A. Feller, Fernando Ovalle, Thomas E. Love, Inmaculada B. Aban, Marjan Mujib, Mustafa I. Ahmed, Stefan D. Anker, Ali Ahmed Tags: Original Articles Source Type: research

Atrial Fibrillation reduces the Functional REServe of the Heart by a fifth: A pilot FRESH-AF study
The advent of catheter ablation has reignited the controversy about whether rhythm or rate control should be the preferred mode of therapy for atrial fibrillation (AF) . It is well known that compared to sinus rhythm (SR), AF is associated with increased mortality and morbidity including stroke, heart failure, and impaired quality of life. Furthermore, patients may experience adverse effects from drug treatment that may negate the beneficial effects of maintaining SR . What is still unknown is in what ways and by how much overall cardiac function is impaired when the atrial “kick” in SR is lost after the onset of AF. T...
Source: International Journal of Cardiology - June 3, 2013 Category: Cardiology Authors: Muzahir H. Tayebjee, Katrina Gilbert, Wanda Macdonald, Andrew J. Hogarth, Nigel T. Lewis, Lip-Bun Tan Tags: Letters to the Editor Source Type: research

Incremental prognostic value of identifying mitral L wave in patients with atrial fibrillation
Atrial fibrillation (AF) is associated with an increased risk of stroke, heart failure and all-cause mortality . AF is frequently associated with left ventricular diastolic dysfunction, resulting in a considerable risk of developing heart failure with preserved ejection fraction . In addition to E-wave and A-wave waves, mitral inflow may have an additional forward flow during mid-diastole, which has been described as a mitral L wave. The appearance of the mitral L wave is reported to be more common in AF than in sinus rhythm and its presence also indicates advanced diastolic dysfunction in patients with and without AF . Ho...
Source: International Journal of Cardiology - July 22, 2013 Category: Cardiology Authors: Ho-Ming Su, Tsung-Hsien Lin, Po-Chao Hsu, Wen-Hsien Lee, Chun-Yuan Chu, Chee-Siong Lee, Wen-Ter Lai, Sheng-Hsiung Sheu, Wen-Chol Voon Tags: Letters to the Editor Source Type: research

Fish oil increase the risk of recurrent atrial fibrillation: Result from a meta-analysis
Atrial fibrillation (AF) is a highly prevalent disease in all over the word, which is responsible for reduced quality of life, costly hospitalizations, heart failure, stroke, and death . No current therapy, drug, device, or ablation is uniformly effective, a number of trials and a meta-analysis suggested that we should be satisfied with ventricular rate control and anticoagulation. Although many factors might contribute to these unsatisfactory results, the limited efficacy and the many and dangerous side effects of antiarrhythmic drugs might be particularly responsible for this failure.
Source: International Journal of Cardiology - July 26, 2013 Category: Cardiology Authors: Xiaocheng Cheng, Shaojie Chen, Qiongwen Hu, Yuehui Yin, Zengzhang Liu Tags: Letters to the Editor Source Type: research

Peak systolic velocity of pulmonary venous flow and mitral annulus are independent predictors of left ventricular global longitudinal strain in patients with cardiomyopathy
Measurement of pulmonary venous flow (PVF) by Doppler echocardiography is a useful tool for evaluating left ventricular (LV) diastolic dysfunction. It is most often used in combination with transmitral flow and tissue Doppler imaging of mitral annular motion in patients with heart failure . Peak systolic velocity (S-vel) of PVF is affected by LV contractility, stroke volume, and decrease in the systolic descent of the mitral annulus . The recently developed two-dimensional (2D) strain imaging, based on speckle tracking echocardiography, is an objective imaging method that allows tracking of longitudinal and circumferential...
Source: International Journal of Cardiology - August 26, 2013 Category: Cardiology Authors: Jun Koyama, Ayako Kozuka, Masatoshi Minamisawa, Hirohiko Motoki, Atsushi Izawa, Takeshi Tomita, Yusuke Miyashita, Masafumi Takahashi, Uichi Ikeda Tags: Letters to the Editor Source Type: research

Pathomorphologic findings in left ventricular hypertrabeculation/noncompaction of adults in relation to neuromuscular disorders
Conclusion: Formaldehyde-fixation should be performed when comparing ECHO with PATHO findings in LVHT. Long-axis as well as short-axis cuts should be carried out in order to assess the course of trabeculations and the extent of the two-layered structure. Subendocardial fibrosis in LVHT deserves further research.
Source: International Journal of Cardiology - October 31, 2013 Category: Cardiology Authors: Daniel Gerger, Claudia Stöllberger, Martin Grassberger, Birgit Gerecke, Horst Andresen, Rolf Engberding, Josef Finsterer Tags: Original Articles Source Type: research

Long-term cardiovascular outcomes in patients with atrial fibrillation and atherothrombosis in the REACH Registry
Abstract: Background: Patients with atrial fibrillation (AF) are at increased risk of thromboembolic events. The long-term prognostic implications of AF in patients with atherothrombosis are unknown.Methods: We compared 4-year CV outcomes in patients with and without a history of AF recorded at their baseline visit in the REACH Registry, an international, prospective cohort of patients with established atherosclerotic arterial disease (CAD, CVD, PAD) or at least 3 risk factors (RFO).Results: AF status and 4year follow-up data were available on 44,518 patients. The prevalence of AF at baseline was 10.3% (n=4582). Overall, p...
Source: International Journal of Cardiology - December 9, 2013 Category: Cardiology Authors: Christian T. Ruff, Deepak L. Bhatt, Ph. Gabriel Steg, Bernard J. Gersh, Mark J. Alberts, Elaine B. Hoffman, E. Magnus Ohman, Kim A. Eagle, Gregory Y.H. Lip, Shinya Goto, On Behalf of the REACH Registry Investigators Tags: Original Articles Source Type: research