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Total 20589 results found since Jan 2013.

Restarting Anticoagulant Therapy After Intracranial Hemorrhage Clinical Sciences
Background and Purpose—The safety and efficacy of restarting anticoagulation therapy after intracranial hemorrhage (ICH) remain unclear. We performed a systematic review and meta-analysis to summarize the associations of anticoagulation resumption with the subsequent risk of ICH recurrence and thromboembolism.Methods—We searched published medical literature to identify cohort studies involving adults with anticoagulation-associated ICH. Our predictor variable was resumption of anticoagulation. Outcome measures were thromboembolic events (stroke and myocardial infarction) and recurrence of ICH. After assessing study het...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Santosh B. Murthy, Ajay Gupta, Alexander E. Merkler, Babak B. Navi, Pitchaiah Mandava, Costantino Iadecola, Kevin N. Sheth, Daniel F. Hanley, Wendy C. Ziai, Hooman Kamel Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Myocardial Infarction, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Dose-Dependent Effect of Statin Pretreatment on Preventing the Periprocedural Complications of Carotid Artery Stenting Clinical Sciences
Background and Purpose—We investigated whether statin pretreatment can dose dependently reduce periprocedural complications in patients undergoing carotid artery stenting because of symptomatic carotid artery stenosis.Methods—We enrolled a consecutive series of 397 symptomatic carotid artery stenosis (≥50% stenosis on conventional angiography) treated with carotid artery stenting at 2 tertiary university hospitals over a decade. Definition of periprocedural complications included any stroke, myocardial infarction, and death within 1 month after or during the procedure. Statin pretreatment was divided into 3 categorie...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Jeong-Ho Hong, Sung-Il Sohn, Jaehyuk Kwak, Joonsang Yoo, Hyuk Won Chang, O-Ki Kwon, Cheolkyu Jung, Inyoung Chung, Hee-Joon Bae, Ji Sung Lee, Moon-Ku Han Tags: Stent, Ischemic Stroke Original Contributions Source Type: research

Peripheral Blood Leukocyte Expression of lncRNA MIAT and Its Diagnostic and Prognostic Value in Ischemic Stroke
Ischemic stroke (IS) is an extremely heterogeneous disease with variable pathogenesis. Due to the lack of early diagnostic markers, the mortality rate of IS remains high. Cumulative evidence shows that long noncoding RNAs among noncoding RNAs play important roles in cardiovascular diseases. In the present study, we focused on the expression pattern of myocardial infarction –associated transcript (MIAT) and its clinical significance in IS.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2017 Category: Neurology Authors: Man Zhu, Nandi Li, Ping Luo, Wei Jing, Xue Wen, Chunzi Liang, Jiancheng Tu Source Type: research

Comparison of Risk Factor Control in the Year After Discharge for Ischemic Stroke Versus Acute Myocardial Infarction Clinical Sciences
Background and Purpose—The Veterans Health Administration has engaged in quality improvement to improve vascular risk factor control. We sought to examine blood pressure (
Source: Stroke - January 22, 2018 Category: Neurology Authors: Dawn M. Bravata, Joanne Daggy, Jared Brosch, Jason J. Sico, Fitsum Baye, Laura J. Myers, Christianne L. Roumie, Eric Cheng, Jessica Coffing, Greg Arling Tags: Ischemic Stroke Original Contributions Source Type: research

Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
AbstractPlatelet microvesicles (PMV) have previously been found elevated in acute ischemic stroke (IS) and could be biomarkers for risk of recurrence. PMV surface antigens such as P-selectin and phosphatidylserine (PS) reflect platelet activation and procoagulance. Tissue factor-positive microvesicles (TF+MV) are considered procoagulant, in particular if co-expressing PS. We enumerated MV subpopulations with these surface antigens in a cohort of 211 patients with primarily non-cardioembolic IS or transient ischemic attack (TIA) and investigated their association with long-term outcome. MV concentrations were determined by ...
Source: Translational Stroke Research - January 24, 2020 Category: Neurology Source Type: research

Role of Colchicine in Stroke Prevention: An Updated Meta-Analysis
Background: Colchicine is a microtubule inhibitor with anti-inflammatory properties. As the body and quality of evidence regarding the efficacy of colchicine for cardiovascular prevention is controversial, the aims of this study was to evaluate the effect of colchicine therapy on vascular events. Methods: A meta-analysis was performed of randomized controlled clinical trials of colchicine on high cardiovascular risk populations, reporting data from stroke, myocardial infarction, cardiovascular mortality and all-cause mortality, after searching the PubMed/MEDLINE, Embase and Cochrane Controlled Trials databases.
Source: Journal of Stroke and Cerebrovascular Diseases - March 8, 2020 Category: Neurology Authors: Walter Masson, Mart ín Lobo, Graciela Molinero, Gerardo Masson, Augusto Lavalle-Cobo Source Type: research

Mild cognitive impairment and receipt of procedures for acute ischemic stroke in older adults
Older patients with pre-existing mild cognitive impairment (MCI) receive less evidence-based care after acute myocardial infarction, however, whether they receive less care after acute ischemic stroke (AIS) is unknown. We compared receipt of guideline-concordant procedures after AIS between older adults with pre-existing MCI and normal cognition.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Deborah A. Levine, Andrzej Galecki, Mohammed Kabeto, Brahmajee K. Nallamothu, Darin B. Zahuranec, Lewis B. Morgenstern, Lynda D. Lisabeth, Bruno Giordani, Kenneth M. Langa Source Type: research

Detection of Myocardial Infarction by Cardiac Magnetic Resonance in Embolic Stroke Related to First Diagnosed Atrial Fibrillation
Elevated troponin levels are found in a significant number of patients who are diagnosed with acute embolic stroke (AES) after first diagnosed atrial fibrillation (AF). These myocardial injuries, which are known as cardiocerebral infarction (CCI), are potentially caused by coronary embolism and correspond to simultaneous cardiac and cerebral embolisms. However, this severe condition remains poorly understood. In this prospective study, we aimed to investigate the prevalence and the cardiac magnetic resonance (CMR) characteristics of CCI.
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2021 Category: Neurology Authors: Adrien Artus, Romain Didier, Margaux Blain, Pierre Comby, Thibault Leclercq, Hugo Debeaumarch é, Frédéric Ricolfi, Marianne Zeller, Yannick Bejot, Alexandre Cochet, Yves Cottin Source Type: research

Educational Program Improved Senior Preparedness to Call 911 as a Response to Stroke
Cardiovascular and cerebrovascular diseases are the leading causes of death in most parts of the world.1 Even though treatment is available, its benefit is highly time-dependent.2,3 Frequently, a minority of patients receive appropriate therapy4 due to low public stroke and heart attack awareness, which leads to delays in medical emergency activation.5 –7
Source: Journal of Stroke and Cerebrovascular Diseases - August 24, 2021 Category: Neurology Authors: Ekaterina Volevach, Hana Mar šálková, Jan Bobek, Veronika Svobodová, Robert Mikulik Source Type: research

Acute Myocardial Infarction after Intravenous Thrombolysis for Acute Ischemic Stroke: Case Series and Systematic Review
Intravenous thrombolysis (IV –rtPA) has been suggested as a potential cause of myocardial infarction (MI) after acute ischemic stroke (AIS), with randomized clinical trials showing a higher number of cardiac events within the thrombolysis group. We assessed the prevalence and MI mechanisms after IV–rtPA for AIS.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2022 Category: Neurology Authors: Jo ão Pedro Marto, Linda Azevedo Kauppila, Cláudia Jorge, Pedro Faustino, João Sargento-Freitas, Liliana Pereira, Sofia Galego, Rafael Dias, Pedro Castro, Teresa Pinho-e-Melo, Ana Catarina Fonseca Source Type: research

New blood test predicts risk of heart attack and stroke with twice previous accuracy
New technique, already available in US, could aid in development of cardiovascular drugsScientists have developed a blood test that can predict whether someone is at high risk of a heart attack, stroke, heart failure or dying from one of these conditions within the next four years.The test, which relies of measurements of proteins in the blood, has roughly twice the accuracy of existing risk scores. It could enable doctors to determine whether patients ’ existing medications are working or whether they need additional drugs to reduce their risk.Continue reading...
Source: Guardian Unlimited Science - April 6, 2022 Category: Science Authors: Linda Geddes Tags: Heart attack Stroke Health Medical research Science World news Society Source Type: news

Intravenous thrombolysis in a patient with acute ischemic stroke associated with a ruptured sinus Valsalva aneurysm: The first case report
Sinus Valsalva aneurysms (SVA) are rare anomalies caused by weakness at the junction of the aortic media and the annulus fibrosus.1 SVAs are clinically silent until they rupture. The rupture can cause right-sided heart failure, myocardial infarction, strokes, and even sudden cardiac death.1 This is the first case report of a patient with a ruptured SVA who presented with acute ischemic stroke and was treated successfully with recombinant tissue-type plasminogen activator (tPA).
Source: Journal of Stroke and Cerebrovascular Diseases - April 29, 2023 Category: Neurology Authors: Mahsa Sepahvand, Mahboubeh Pazoki, Maziar Emamikhah, Narges Yazdi Tags: Case Report Source Type: research

Ability of the DANCAMI to predict the risk ischemic stroke and mortality in patients with atrial fibrillation/flutter
Comparison of the danish comorbidity index for acute myocardial infarction (DANCAMI), the charlson comorbidity index (CCI), the elixhauser comorbidity index (ECI), and the CHA2DS2-VASc score to predict ischemic stroke, cardiovascular mortality, and all-cause mortality after atrial fibrillation/flutter.
Source: Journal of Stroke and Cerebrovascular Diseases - July 13, 2023 Category: Neurology Authors: Kasper Bonnesen, Uffe Heide-J ørgensen, Henrik Toft Sørensen, Morten Schmidt Source Type: research

Age- and Sex-Associated Impacts of Body Mass Index on Stroke Type Risk: A 27-Year Prospective Cohort Study in a Low-Income Population in China
Conclusions Being overweight increased the risk of both ischemic and hemorrhagic strokes; obesity was only associated with an increased risk of IS. Additionally, the positive association between BMI and stroke risk was only observed in participants aged <65 years and the associations differed between men and women. Being overweight increased the risk of both ischemic and hemorrhagic strokes in men and being underweight increased their risk of hemorrhagic stroke. In women, being overweight increased the hemorrhagic stroke risk, whereas obesity increased their IS risks. The high prevalence of hypertension and elevat...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II
Conclusion: In ischemic stroke or TIA patients with platelet count within normal range, platelet count may be a qualified predictor for long-term recurrent stroke, mortality, and poor functional outcome. Introduction Platelets exert a critical role in the pathogenesis of atherosclerotic complications of cardio-cerebrovascular disease, contributing to thrombus formation, and embolism (1, 2). Previous literature reported that platelets of various size and density are produced by megakaryocytes of different size and stages of maturation in different clinical conditions, suggesting various platelet patterns in differen...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research