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Condition: Heart Attack

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Total 20589 results found since Jan 2013.

Real-World Setting Comparison of Nonvitamin-K Antagonist Oral Anticoagulants Versus Vitamin-K Antagonists for Stroke Prevention in Atrial Fibrillation Clinical Sciences
Conclusions—This meta-analysis confirms the main findings of the randomized controlled trials of dabigatran, rivaroxaban, and apixaban in the real-world setting and, hence, strengthens their validity.
Source: Stroke - August 28, 2017 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Konstantinos Makaritsis, Konstantinos Vemmos, Patrik Michel, Gregory Y.H. Lip Tags: Arrhythmias, Secondary Prevention, Meta Analysis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Baseline Quality of Life and Risk of Stroke in the ALLHAT Study (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) Clinical Sciences
Conclusions—The lowest baseline TQoL quartile had a 20% higher stroke risk than the highest quartile. Baseline TQoL was the only factor that predicted poststroke change in TQoL.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00000542.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Tanzila Shams, Alexander P. Auchus, Suzanne Oparil, Clinton B. Wright, Jackson Wright, Anthony J. Furlan, Cathy A. Sila, Barry R. Davis, Sara Pressel, Jose-Miguel Yamal, Paula T. Einhorn, Alan J. Lerner Tags: Lifestyle, Primary Prevention, Risk Factors, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Residential Proximity to Major Roadways and Risk of Incident Ischemic Stroke in NOMAS (The Northern Manhattan Study) Clinical Sciences
Conclusions—In this urban multiethnic cohort, we found evidence supporting that within-city variation in residential proximity to major roadway is associated with higher risk of ischemic stroke. An individual’s smoking history modified this association, with the association remaining only among participants not currently smokers.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Erin R. Kulick, Gregory A. Wellenius, Amelia K. Boehme, Ralph L. Sacco, Mitchell S. Elkind Tags: Aging, Cardiovascular Disease, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Smoking and Risk of Ischemic Stroke in Young Men Brief Report
We examined the dose–response relationship between the quantity of cigarettes smoked and the odds of developing an ischemic stroke in men under age 50 years.Methods—The Stroke Prevention in Young Men Study is a population-based case–control study of risk factors for ischemic stroke in men ages 15 to 49 years. The χ2 test was used to test categorical comparisons. Logistic regression models were used to calculate the odds ratio for ischemic stroke occurrence comparing current and former smokers to never smokers. In the first model, we adjusted solely for age. In the second model, we adjusted for potential confounding ...
Source: Stroke - April 23, 2018 Category: Neurology Authors: Janina Markidan, John W. Cole, Carolyn A. Cronin, Jose G. Merino, Michael S. Phipps, Marcella A. Wozniak, Steven J. Kittner Tags: Epidemiology, Primary Prevention, Risk Factors, Secondary Prevention, Ischemic Stroke Brief Reports Source Type: research

Trends in Risk Factor Prevalence and Management Before First Stroke: Data From the South London Stroke Register 1995-2011 Clinical Sciences
Conclusions— Antiplatelet and cholesterol-lowering treatment prescribing have improved significantly over time; however, only a minority with AF received anticoagulants, and this did not improve significantly. Overall, 30% of strokes occurred in patients with previously diagnosed but untreated risk factors.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Marshall, I. J., Wang, Y., McKevitt, C., Rudd, A. G., Wolfe, C. D. A. Tags: Primary prevention, Anticoagulants, Antiplatelets, Other Stroke Treatment - Medical, Epidemiology Clinical Sciences Source Type: research

Race/Ethnic Differences in the Risk of Hemorrhagic Complications Among Patients With Ischemic Stroke Receiving Thrombolytic Therapy Clinical Sciences
Conclusions— In patients with stroke receiving tPA, hemorrhagic complications were slightly higher in blacks and Asians, but not in Hispanics compared with whites. Asians also faced significantly higher risk for sICH relative to other race/ethnic groups. Future studies are needed to evaluate whether reduction in tPA dose similar to that used in many Asian countries could improve the safety of tPA therapy in Asians in the United States with acute ischemic strokes while maintaining efficacy.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Mehta, R. H., Cox, M., Smith, E. E., Xian, Y., Bhatt, D. L., Fonarow, G. C., Peterson, E. D., for the Get With The Guidelines-Stroke Program Tags: Thrombolysis Clinical Sciences Source Type: research

Dynamic Magnetic Resonance Angiography Provides Collateral Circulation and Hemodynamic Information in Acute Ischemic Stroke Brief Reports
Conclusions— As a fast, direct, feasible, noninvasive, and reliable method to assess site of occlusion, collateral circulation and hemodynamic alterations, dMRA provides profound insights in acute stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Hernandez-Perez, M., Puig, J., Blasco, G., Perez de la Ossa, N., Dorado, L., Davalos, A., Munuera, J. Tags: Imaging, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Prevalence of Positive Troponin and Echocardiogram Findings and Association With Mortality in Acute Ischemic Stroke Clinical Sciences
Conclusions—Hypertroponinemia in the context of AIS without concurrent myocardial infarction was associated with structural cardiac disease and long-term mortality. Prospective studies are needed to determine whether further cardiac evaluation might improve the long-term mortality rates seen in this group.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Peter Wrigley, Jane Khoury, Bryan Eckerle, Kathleen Alwell, Charles J. Moomaw, Daniel Woo, Mathew L. Flaherty, Felipe De Los Rios la Rosa, Jason Mackey, Opeolu Adeoye, Sharyl Martini, Simona Ferioli, Brett M. Kissela, Dawn O. Kleindorfer Tags: Myocardial Infarction, Mortality/Survival, Cerebrovascular Disease/Stroke, Vascular Disease Original Contributions Source Type: research

Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin Clinical Sciences
Conclusions—In anticoagulated patients with atrial fibrillation and risk factors for stroke, echocardiographic findings do not seem to add to the risk of thromboembolic events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00412984.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Dragos Vinereanu, Renato D. Lopes, Hillary Mulder, Bernard J. Gersh, Michael Hanna, Pedro G.M. de Barros e Silva, Dan Atar, Lars Wallentin, Christopher B. Granger, John H. Alexander Tags: Arrhythmias, Echocardiography, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Serum Hepatocyte Growth Factor Is Probably Associated With 3-Month Prognosis of Acute Ischemic Stroke Clinical Sciences
Background and Purpose—Serum hepatocyte growth factor (HGF) is positively associated with poor prognosis of heart failure and myocardial infarction, and it can also predict the risk of ischemic stroke in population. The goal of this study was to investigate the association between serum HGF and prognosis of ischemic stroke.Methods—A total of 3027 acute ischemic stroke patients were included in this post hoc analysis of the CATIS (China Antihypertensive Trial in Acute Ischemic Stroke). The primary outcome was composite outcome of death or major disability (modified Rankin Scale score ≥3) within 3 months.Results—Afte...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Zhengbao Zhu, Tan Xu, Daoxia Guo, Xinfeng Huangfu, Chongke Zhong, Jingyuan Yang, Aili Wang, Chung-Shiuan Chen, Yanbo Peng, Tian Xu, Jinchao Wang, Yingxian Sun, Hao Peng, Qunwei Li, Zhong Ju, Deqin Geng, Jing Chen, Yonghong Zhang, Jiang He Tags: Biomarkers, Clinical Studies, Epidemiology, Prognosis, Ischemic Stroke Original Contributions Source Type: research

Smoking-Thrombolysis Paradox: Recanalization and Reperfusion Rates After Intravenous Tissue Plasminogen Activator in Smokers With Ischemic Stroke Original Contributions
Conclusions— Smoking is independently associated with recanalization and reperfusion, indicating that thrombolytic therapy acts more effectively in smokers; because of small numbers, these results should be considered preliminary. Clinical Trial Registration— URL: http://clinicaltrials.gov. Unique Identifier: NCT00715533.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Kufner, A., Nolte, C. H., Galinovic, I., Brunecker, P., Kufner, G. M., Endres, M., Fiebach, J. B., Ebinger, M. Tags: Fibrinolysis, Angiography, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke, Thrombolysis Original Contributions Source Type: research

Antithrombotic Therapy After Acute Ischemic Stroke in Patients With Atrial Fibrillation Clinical Sciences
Conclusions— Contrary to current guidelines, 30% of patients with atrial fibrillation and recent IS are not prescribed any OAC therapy on discharge, whereas a further 30% are prescribed combination OAC and antiplatelet therapy. Combination OAC and antiplatelet therapy in patients at high cardiovascular risk requires evaluation in clinical trials, particularly with the newer OACs, given their more favorable risk–benefit ratio compared with warfarin.
Source: Stroke - November 24, 2014 Category: Neurology Authors: McGrath, E. R., Kapral, M. K., Fang, J., Eikelboom, J. W., Conghaile, A. O., Canavan, M., O'Donnell, M. J., on behalf of the Investigators of the Ontario Stroke Registry Tags: Secondary prevention, Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs Clinical Sciences Source Type: research

Detection of Left Ventricular Thrombus by Cardiac Magnetic Resonance in Embolic Stroke of Undetermined Source Clinical Sciences
Background and Purpose—We aimed to use contrast-enhanced cardiac magnetic resonance (CE-CMR) imaging to elucidate the prevalence of left ventricular (LV) thrombus in patients suspected of embolic stroke of undetermined source (ESUS) with previous myocardial infarction or LV dysfunction (LV ejection fraction [LVEF]
Source: Stroke - August 28, 2017 Category: Neurology Authors: Junji Takasugi, Hiroshi Yamagami, Teruo Noguchi, Yoshiaki Morita, Tomotaka Tanaka, Yoshinori Okuno, Satoshi Yasuda, Kazunori Toyoda, Yasufumi Gon, Kenichi Todo, Manabu Sakaguchi, Kazuyuki Nagatsuka Tags: Diagnostic Testing, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Embolism, Thrombosis Original Contributions Source Type: research

Incidence and Outcomes of Myocardial Infarction in Patients Admitted With Acute Ischemic Stroke Clinical Sciences
Background and Purpose—Data on the incidence and outcomes of acute myocardial infarction (AMI) complicating acute ischemic stroke (AIS) are limited. We aim to evaluate the incidence, treatment patterns, and outcomes of AMI in patients with AIS using a nationwide database.Methods—The National Inpatient Sample was used to identify patient with AIS between 2003 and 2014. Trends of incidence of AMI and its associated in-hospital mortality were evaluated. Univariate and multivariate logistic regressions were used to evaluate predictors of AMI. The impact of AMI on in-hospital outcomes was assessed in a comparative analysis ...
Source: Stroke - October 23, 2017 Category: Neurology Authors: Fahad Alqahtani, Sami Aljohani, Abdul Tarabishy, Tatiana Busu, Amelia Adcock, Mohamad Alkhouli Tags: Myocardial Infarction, Ischemic Stroke Original Contributions Source Type: research

Self-Report of Stroke, Transient Ischemic Attack, or Stroke Symptoms and Risk of Future Stroke in the Reasons for Geographic And Racial Differences in Stroke (REGARDS) Study Original Contributions
Conclusions— Results suggest a spectrum of risk from stroke symptoms to TIA, DS, and RS, and imply a need for establishing these categories in health screenings to manage risk for future stroke, reinforcing the clinical importance of stroke history including the presence of stroke symptoms.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Judd, S. E., Kleindorfer, D. O., McClure, L. A., Rhodes, J. D., Howard, G., Cushman, M., Howard, V. J. Tags: Epidemiology Original Contributions Source Type: research