Smoking and Risk of Ischemic Stroke in Young Men [Brief Report]

We examined the dose–response relationship between the quantity of cigarettes smoked and the odds of developing an ischemic stroke in men under age 50 years.Methods—The Stroke Prevention in Young Men Study is a population-based case–control study of risk factors for ischemic stroke in men ages 15 to 49 years. The χ2 test was used to test categorical comparisons. Logistic regression models were used to calculate the odds ratio for ischemic stroke occurrence comparing current and former smokers to never smokers. In the first model, we adjusted solely for age. In the second model, we adjusted for potential confounding factors, including age, race, education, hypertension, myocardial infarction, angina, diabetes mellitus, and body mass index.Results—The study population consisted of 615 cases and 530 controls. The odds ratio for the current smoking group compared with never smokers was 1.88. Furthermore, when the current smoking group was stratified by number of cigarettes smoked, there was a dose–response relationship for the odds ratio, ranging from 1.46 for those smoking

Source: Stroke - April 23, 2018 Category: Neurology Authors: Janina Markidan, John W. Cole, Carolyn A. Cronin, Jose G. Merino, Michael S. Phipps, Marcella A. Wozniak, Steven J. Kittner Tags: Epidemiology, Primary Prevention, Risk Factors, Secondary Prevention, Ischemic Stroke Brief Reports Source Type: research