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Total 229 results found since Jan 2013.

Role of Brain Biomarker in Predicting Clinical Outcome in Hypertensive Cerebrovascular Ischemic Stroke
This study was undertaken to evaluate the role of serum neuron specific enolase (NSE) in prediction of disability and neurological worsening in hypertensive ischemic cerebrovascular stroke. 80 hypertensive ischemic stroke patients diagnosed by a neurologist as per WHO definition along with radiological findings suggestive of cerebrovascular stroke and differentiating from hemorrhagic stroke and 60 controls having essential hypertension coming to hospital because of regular checkup or headache but with no neurological disease were included in the study. Neurological disability was assessed by NIHSS at the time of admission ...
Source: Indian Journal of Clinical Biochemistry - April 1, 2018 Category: Biochemistry Source Type: research

Fluoxetine or Venlafaxine for Early Post Stroke Depression
Conclusions: PSD in the early phase affects a substantial number of the stroke patients. Venlafaxine has got a better outcome and adverse event profile compared to fluoxetine in this group of patients. However, larger multicenter studies will provide more helpful data in this area.
Source: Neurology India - December 19, 2022 Category: Neurology Authors: Vivek K Nambiar J Parvathy Tania M Philip K Abhijith S Sreeni Naveen K Panicker Amrutha V Ajai TS Dhanya Source Type: research

Chorea-ballism as a dominant clinical manifestation in heteroplasmic mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes syndrome with A3251G mutation in mitochondrial genome: a case report
ConclusionThe dominance of hyperkinetic movements in the clinical scenario and the finding of a point mutation A3251G inMT-TL1 gene make this a rare presentation.
Source: Journal of Medical Case Reports - March 5, 2019 Category: General Medicine Source Type: research

Differential Characteristics of Ischemic and Hemorrhagic Stroke in Patients with Cerebral Small Vessel Disease
Conclusion: Identification of differential clinical and prognostic profile between ischemic and hemorrhagic consequences of underlying cerebral SVD is useful for risk stratification in the current process pursuing precision medicine.
Source: Neurology India - February 24, 2021 Category: Neurology Authors: Mireia Bernal Paula Escarcena Adri & #224; Arboix Lluis Garcia-Eroles Enric Verg & #233;s Laura D & #237;ez Joan Massons Source Type: research

Arterial Ischemic Stroke —Peculiarities of Clinical Presentation and Risk Factors in Indian Children
Neuropediatrics DOI: 10.1055/s-0041-1728773There are not enough recent studies on arterial ischemic stroke (AIS) in Indian children. We retrospectively reviewed data on 95 children (69 boys), aged 3 months to 17 years, with AIS. Focal signs were noted in 84 (88%) with hemiparesis in 72 (76%). Diffuse signs were present in 33 (35%) with fever in 22 (23%), altered mental status in 20 (21%), and headache in 12 (13%). Seizures occurred in 29 (31%) children. Arteriopathy was observed in 57 (60%) children with mineralizing lenticulostriate vasculopathy (mLSV) in 22 (23%) being the most common, followed by moyamoya in 14 (15%), a...
Source: Neuropediatrics - June 8, 2021 Category: Neurology Authors: Goraya, Jatinder Singh Berry, Shivankshi Kaur, Amandeep Singh, Gagandeep Tags: Original Article Source Type: research

Craniovertebral Junction Anomalies: An Overlooked Cause of & #39;Posterior Circulation Stroke & #39;
Conclusions: CVJ anomalies can present as posterior circulation infarct. One must evaluate all patients with posterior circulation stroke, especially young patients, for possible CVJ anomalies. Dynamic lateral cervical spine X-ray is an important tool to diagnose AAD. CVJ anomalies represent a treatable cause of VAD.
Source: Neurology India - November 11, 2022 Category: Neurology Authors: Kanwaljeet Garg Vivek Tandon Rajinder Kumar P Sarat Chandra Shashank S Kale Bhawani Shankar Sharma Ashok K Mahapatra Source Type: research

Interesting Case of Stroke.
We report regarding a 46 year old female patient, who presented with complaints of severe headache and right sided weakness. Examination revealed right Hemiplegia with BP of 144/90 mm Hg. Investigations revealed Creatine Kinase: 470IU/L, normal Blood counts, ESR and CRP. Thyroid profile was normal. Fibrinogen levels were 17.9mg/dl and repeat test after 1 week showed 24.6mg/dl. ECG showed incomplete left bundle branch block. Echocardiography was normal. PMID: 31311228 [PubMed - in process]
Source: Journal of the Association of Physicians of India - July 18, 2019 Category: General Medicine Tags: J Assoc Physicians India Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Epidemiology of Moyamoya Angiopathy in Eastern India
ConclusionMMA is an important etiological consideration in patients with stroke, especially in children. It can present with a myriad of transient neurological symptoms, frequently overlooked, leading to delayed diagnosis, and contributing to socio-economic burden. Indian MMA showed aberrations in its gender predisposition, age distribution, frequency of familial cases, disease manifestation, and type of stroke, in comparison to its Japanese and Caucasian counterparts pointing to the inter- and intra-continent differences of MMA phenotype. Future development of the Indian MMA national registry is of essence.
Source: Frontiers in Neurology - March 4, 2022 Category: Neurology Source Type: research

Migraine and Vascular Risk: An Update
Conclusion: Although the absolute effect of migraine on 'vascular risks' is small, good practice parameters dwell on treating and reducing existing cardiovascular risk factors through lifestyle modification, encouraging smoking cessation, and advocating the wise use of agents like ergot alkaloids and oral contraceptives, after a risk-benefit analysis.
Source: Neurology India - May 14, 2021 Category: Neurology Authors: Anu Gupta M V Padma Srivastava Source Type: research

Harnessing the Four Elements for Mental Health
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is pre...
Source: Frontiers in Psychiatry - April 23, 2019 Category: Psychiatry Source Type: research

Immunological biomarkers in neuropsychiatric systemic lupus erythematosus: a comparative cross-sectional study from a tertiary care center in South India.
CONCLUSION: No single biomarker correlated with NPSLE. Among different NPSLE manifestations, the prevalence of IgG β2GP1 in stroke, LA in demyelination, anti-ribosomal P in psychosis and anti-myelin oligodendrocyte glycoprotein in mood disorder were higher. Further studies on the pathogenic mechanisms underlying NPSLE and its different manifestations may help us to identify better biomarkers. PMID: 32106787 [PubMed - as supplied by publisher]
Source: Lupus - February 26, 2020 Category: Rheumatology Authors: Seth G, Sundaresh A, Mariaselvam CM, Kumar G, Chengappa KG, Adarsh MB, Tamouza R, Negi VS Tags: Lupus Source Type: research

A Retrospective Observational Study of Neurological Manifestations in COVID-19 (SON-CoV)
Conclusion: CNS symptoms of COVID-19 are more common than PNS symptoms. Stroke is the most frequent (46%) COVID-CNS symptom, which occurs in people of age above 35 years and is associated with high mortality.PMID:37355862 | DOI:10.5005/japi-11001-0107
Source: Journal of the Association of Physicians of India - June 25, 2023 Category: General Medicine Authors: Neetu Ramrakhiani Neeraj Bhutani Deepak Chaudhary Pooja Parab Karni Singh Priya Agrawal Vikas Gupta Source Type: research

Cerebral infarction and cortical subarachnoid hemorrhage preceded vascular contraction in reversible cerebral vasoconstriction syndrome patient with hidden breast cancer
We report a case of RCVS with hidden breast cancer in which ischemic stroke and cortical subarachnoid hemorrhage were observed earlier than vasoconstriction, and there were positive autoantibodies.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Changhyo Yoon Seunguk Jung Source Type: research

Primary angiitis of the central nervous system: Clinical profiles and outcomes of 45 patients
Conclusion: In this cohort, severe deficits and cognitive symptoms at onset and an abnormal EEG were associated with a poor 6-month outcome.
Source: Neurology India - March 6, 2019 Category: Neurology Authors: Soumya Sundaram Deepak Menon Pooja Khatri Sapna Erat Sreedharan ER Jayadevan Prabhakaran Sarma Christian Pagnoux PN Sylaja Source Type: research