Filtered By:
Condition: Hypertrophic Cardiomyopathy

This page shows you your search results in order of relevance. This is page number 17.

Order by Relevance | Date

Total 437 results found since Jan 2013.

Fabry disease in cardiology: Diagnosis and therapeutic approaches
Turk Kardiyol Dern Ars. 2020 Dec;48(Suppl 2):1-42. doi: 10.5543/tkda.2020.38262.ABSTRACTFabry disease is a rare, progressive, X-linked inherited storage disorder due to absent or deficient of lysosomal alfa galactosidase A activity. Deficient activity of alfa-galactosidase A results in progressive accumulation of globotriaosylceramide in a variety of tissues and organs including myocardium, kidney and nerve system. This disorder predominantly affects males; however, female heterozygotes may also be affected with a less severe clinical picture. Classic Fabry disease is usually diagnosed in early age of childhood because of ...
Source: Turk Kardiyoloji Dernegi arsivi - January 21, 2021 Category: Cardiology Authors: Y üksel Çavuşoğlu Ebru Özpelit Nur Arslan Mesut Demir G ökhan Kahveci H üseyin Onay Emir Özgür Barış Ökçün Oma ç Tufekcioglu Selcen Yakar T ülüce Gonca K ılıç Yıldırım Source Type: research

Genes, Vol. 12, Pages 408: KLF15 Loss-of-Function Mutation Underlying Atrial Fibrillation as well as Ventricular Arrhythmias and Cardiomyopathy
Yang Min Zhang Atrial fibrillation (AF) represents the most common type of clinical cardiac arrhythmia and substantially increases the risks of cerebral stroke, heart failure and death. Accumulating evidence has convincingly demonstrated the strong genetic basis of AF, and an increasing number of pathogenic variations in over 50 genes have been causally linked to AF. Nevertheless, AF is of pronounced genetic heterogeneity, and the genetic determinants underpinning AF in most patients remain obscure. In the current investigation, a Chinese pedigree with AF as well as ventricular arrhythmias and hypertrophic cardiomyo...
Source: Genes - March 12, 2021 Category: Genetics & Stem Cells Authors: Ning Li Ying-Jia Xu Hong-Yu Shi Chen-Xi Yang Yu-Han Guo Ruo-Gu Li Xing-Biao Qiu Yi-Qing Yang Min Zhang Tags: Article Source Type: research

Fabry disease in cardiology: Diagnosis and therapeutic approaches
Turk Kardiyol Dern Ars. 2020 Dec;48(Suppl 2):1-42. doi: 10.5543/tkda.2020.38262.ABSTRACTFabry disease is a rare, progressive, X-linked inherited storage disorder due to absent or deficient of lysosomal alfa galactosidase A activity. Deficient activity of alfa-galactosidase A results in progressive accumulation of globotriaosylceramide in a variety of tissues and organs including myocardium, kidney and nerve system. This disorder predominantly affects males; however, female heterozygotes may also be affected with a less severe clinical picture. Classic Fabry disease is usually diagnosed in early age of childhood because of ...
Source: Turk Kardiyoloji Dernegi arsivi - January 21, 2021 Category: Cardiology Authors: Y üksel Çavuşoğlu Ebru Özpelit Nur Arslan Mesut Demir G ökhan Kahveci H üseyin Onay Emir Özgür Barış Ökçün Oma ç Tufekcioglu Selcen Yakar T ülüce Gonca K ılıç Yıldırım Source Type: research

Cardiac disease in pregnancy: hypertrophic obstructive cardiomyopathy and pulmonic stenosis
The prevalence of cardiovascular disease in pregnancy is increasing and cardiovascular disease is the leading cause of pregnancy-related death in the United States.1 The physiologic adaptations to pregnancy include an increased heart rate, stroke volume, and substantial expansion in circulatory volume, which may pose significant cardiac stress to patients with cardiac disease. During labor, cardiac output increases further and maternal expulsive efforts during the second stage of labor, with the decreased preload and increased afterload that accompany the Valsalva maneuver, may provoke decompensation in vulnerable patients.
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 26, 2021 Category: Anesthesiology Authors: David E. Arnolds, Chad Dean, Mohammed Minhaj, William T. Schnettler, Jennifer Banayan, Mark A. Chaney Tags: Case Conference Source Type: research

Prognostic impact of newly detected atrial fibrillation in patients with hypertrophic cardiomyopathy following cardiac implantable electronic device implantation
In conclusion, the incidence of newly detected AF after CIED implantations in HCM patients was high. The newly detected AF was associated with worsening heart failure and careful follow-up is recommended.
Source: Heart and Vessels - April 9, 2021 Category: Cardiology Source Type: research

The benefits and challenges of family genetic testing in rare genetic diseases-lessons from Fabry disease
CONCLUSION: In this review, the worldwide experience of an international group of experts of Fabry disease highlights the issues faced in the family genetic testing of patients affected with rare genetic diseases.PMID:33835733 | DOI:10.1002/mgg3.1666
Source: Molecular Medicine - April 9, 2021 Category: Molecular Biology Authors: Dominique P Germain Sergey Moiseev Fernando Su árez-Obando Faisal Al Ismaili Huda Al Khawaja Gheona Altarescu Fellype C Barreto Farid Haddoum Fatemeh Hadipour Irina Maksimova Mirelle Kramis Sheela Nampoothiri Khanh Ngoc Nguyen Dau-Ming Niu Juan Politei L Source Type: research

Hypertrophic cardiomyopathy considerations for the managed care pharmacist
Am J Manag Care. 2021 Apr;27(6 Suppl):S118-S125. doi: 10.37765/ajmc.2021.88629.ABSTRACTHypertrophic cardiomyopathy (HCM) is often seen in patients as an autosomal dominant genetic heart disease with a variable clinical course. It is characterized by left ventricular hypertrophy, and with some patients, there is no evidence of a genetic etiology or presence of HCM in family members. Young age at diagnosis and the presence of a pathogenic or likely pathogenic sarcomere variant predict greater lifelong risk for stroke, heart failure, ventricular arrhythmia, atrial fibrillation, or mortality. Most individuals affected with HCM...
Source: The American Journal of Managed Care - April 16, 2021 Category: Health Management Authors: Patty Taddei-Allen Source Type: research

The benefits and challenges of family genetic testing in rare genetic diseases —lessons from Fabry disease
ConclusionIn this review, the worldwide experience of an international group of experts of Fabry disease highlights the issues faced in the family genetic testing of patients affected with rare genetic diseases.
Source: Molecular Genetics & Genomic Medicine - April 9, 2021 Category: Genetics & Stem Cells Authors: Dominique P. Germain, Sergey Moiseev, Fernando Su árez‐Obando, Faisal Al Ismaili, Huda Al Khawaja, Gheona Altarescu, Fellype C. Barreto, Farid Haddoum, Fatemeh Hadipour, Irina Maksimova, Mirelle Kramis, Sheela Nampoothiri, Khanh Ngoc Nguyen Tags: REVIEW ARTICLE Source Type: research

Clinical characteristics and outcomes in childhood-onset hypertrophic cardiomyopathy
ConclusionPatients with childhood-onset HCM are more likely to have sarcomeric disease, carry a higher risk of life-threatening ventricular arrythmias, and have greater need for advanced HF therapies. These findings provide insight into the natural history of disease and can help inform clinical risk stratification.
Source: European Heart Journal - March 26, 2021 Category: Cardiology Source Type: research

Hypertrophic cardiomyopathies requiring more monitoring for less atrial fibrillation-related complications: a clustering analysis based on the French registry on hypertrophic cardiomyopathy (REMY)
ConclusionBased on a clustering analysis, three phenogroups of HCM according to the risk of AF occurrence can be identified. It can indicate which patients should be more monitored and/or treated, particular to prevent the risk of stroke.Graphic abstract
Source: Clinical Research in Cardiology - May 27, 2021 Category: Cardiology Source Type: research

Clinical significance of new ‐onset atrial fibrillation in patients with hypertrophic cardiomyopathy
ConclusionsIn our HCM registry in an aged Japanese community, a significant proportion developed AF. The presence of AF, particularly new-onset AF, was associated with increased incidence of HCM-related events. AF may not be just a marker of disease stage but an important trigger of adverse events.
Source: ESC Heart Failure - September 2, 2021 Category: Cardiology Authors: Toru Kubo, Yuichi Baba, Yuri Ochi, Takayoshi Hirota, Naohito Yamasaki, Kazuya Kawai, Katsuhito Yamamoto, Fumiaki Kondo, Kanji Bando, Eisuke Yamada, Takashi Furuno, Toshikazu Yabe, Yoshinori L. Doi, Hiroaki Kitaoka Tags: Original Research Article Source Type: research