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Condition: Carbon Monoxide Poisoning

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Total 437 results found since Jan 2013.

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Application and prospects of butylphthalide for the treatment of neurologic diseases.
CONCLUSIONS: The varied pharmacologic mechanisms of NBP involve many complex molecular mechanisms; however, there many unknown pharmacologic effects await further study. PMID: 31205106 [PubMed - in process]
Source: Chinese Medical Journal - June 18, 2019 Category: General Medicine Authors: Chen XQ, Qiu K, Liu H, He Q, Bai JH, Lu W Tags: Chin Med J (Engl) Source Type: research

What Types of Memory Impairments are There in Children?
Discussion Memory is an important part of what distinguishes higher order species from others. Memory also is part of one’s self-identity. Difficulties in short-term memory can make common, everyday tasks difficult for the person experiencing the problem particularly if it recently occurred and the person’s long-term memory is intact. Difficulties with long-term memory can also have problems when language, events or even one’s own identity are affected. For some people the memory loss is temporary but for others, memory impairments are permanent and must be accepted and accommodated as part of the overall...
Source: PediatricEducation.org - March 30, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Toxic lipstick, carbon monoxide tragedy, laundry detergent pod death: Weekly Web Review in Toxicology
Meth Labs and the Pharmaceutical Industry: Jonah Engle’s article in Mother Jones — “Merchants of Meth: How Big Pharma Keeps the Cooks in Business” — is compelling reading. The piece details how some drug companies lobbying firms are fighting efforts to control sale of the  meth precursor pseudoephedrine: As law enforcement agencies scramble to clean up and dispose of toxic [meth] labs, prosecute cooks, and find foster homes for their children, they are waging two battles: one against destitute, strong-out addicts, the other against some of the world’s wealthiest and most politically connected ...
Source: The Poison Review - August 21, 2013 Category: Toxicology Authors: Leon Tags: Medical big pharma carbon monoxide heavy metals laundry detergent pod methamphetamine toxic lipstick Source Type: news

Does an Alzheimer's disease susceptibility gene influence the cognitive effects of cancer therapy?
Abstract The apolipoprotein E (APOE) e4 allele is the most prevalent genetic risk factor for Alzheimer's disease (AD). APOE e4 carriers suffer greater morbidity from head trauma, stroke, and carbon monoxide poisoning, yet possible interactions between APOE genotype and cancer therapy on cognition are unclear. Neuropathological and biomarker studies of young asymptomatic APOE e4 carriers that show elevated neocortical amyloid and medial temporal neurofibrillary tangles and longitudinal neuropsychological studies that show accelerated memory decline beginning around age 55–60 years define preclinical AD and have set the st...
Source: Pediatric Blood and Cancer - September 17, 2013 Category: Cancer & Oncology Authors: Richard J. Caselli Tags: Review Source Type: research

S100B protein in children with carbon monoxide poisoning
S100B has been shown to increase in patients with cardiac arrest, stroke, subarachnoid hemorrhage, and traumatic and hypoxic brain damage . In contrast to adult studies, we found that serum S100B protein levels did not increase in pediatric patients with carbon monoxide (CO) poisoning . Patients with a positive history of CO exposure and elevated blood carboxyhemoglobin (>10%) levels associated with relevant clinical findings were diagnosed with CO poisoning. The most common complaints were headache (n = 27), dizziness (n = 27), nausea and vomiting (n = 28), syncope (n = 7), and convulsion (n = 2). In addition, we also cla...
Source: The American Journal of Emergency Medicine - August 12, 2013 Category: Emergency Medicine Authors: Ahmet Zulfikar Akelma, Aydin Celik,, Osman Ozdemir, Fatma Kavak Akelma Tags: Correspondence Source Type: research

Combined Treatment of Methylprednisolone Pulse and Memantine Hydrochloride Prompts Recovery from Neurological Dysfunction and Cerebral Hypoperfusion in Carbon Monoxide Poisoning: A Case Report
A 49-year-old healthy man developed sudden unconsciousness under inadequate ventilation. Blood gas analysis showed carboxyhemoglobin of 7.3%. After normobaric oxygen therapy, he recovered completely 7 days later. At 3 weeks after carbon monoxide (CO) exposures, memory and gait disturbances appeared. Neurological examination revealed Mini-Mental State Examination (MMSE) score of 5 of 30 points, leg hyper-reflexia with Babinski signs, and Parkinsonism. Brain fluid-attenuated inversion recovery imaging disclosed symmetric hypointense lesions in the thalamus and the globus pallidus, and hyperintense lesions in the cerebral w...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2013 Category: Neurology Authors: Konosuke Iwamoto, Ken Ikeda, Sunao Mizumura, Kazuhiro Tachiki, Masaru Yanagihashi, Yasuo Iwasaki Tags: Case Reports Source Type: research

Akinetic Mutism And Parkinsonian Features Progressing To Coma Following A Hypoxic Event With Extended Lucid Interval: Manifestations Of Delayed Post-Hypoxic Leukoencephalopathy (P4.033)
CONCLUSIONS: Clinical anticipation and recognition of DPHL should lead to earlier diagnosis and higher-value care.Disclosure: Dr. Doerner Rinaldi has nothing to disclose. Dr. Miller has nothing to disclose. Dr. Czeisler has nothing to disclose. Dr. Willey has nothing to disclose. Dr. John has nothing to disclose. Dr. Claassen has nothing to disclose. Dr. Mayer has received personal compensation for activities with Actelion, Baxter, Biogen Idec, Codman/Johnson & Johnson Company, CSL Behring, Cornerstone Therapeutics, CR Bard, Novartis, Orsan Technologies, Pfizer Inc, Sage Therapeutics, and Stryker. Dr. Mayer has receive...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Doerner Rinaldi, A. P., Miller, E., Czeisler, B., Willey, J., John, C., Claassen, J., Mayer, S., Agarwal, S. Tags: General Neurology III Source Type: research

Unusual Presentation of Acute Carbon Monoxide Poisoning (P6.024)
CONCLUSIONCO poisoning should be included in the differential diagnosis of patients found to have isolated bilateral thalamic involvement. MR imaging undertaken in acute setting aids in management and prognosis. Follow-up is required to assess for the development of Delayed Neuropsychiatric Syndrome, which can cause changes in personality, memory and gait.Disclosure: Dr. Bains has nothing to disclose. Dr. Reid has nothing to disclose. Dr. Huang has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bains, S., Reid, D., Huang, X. Tags: General Neurology VI Source Type: research

Short-term effects of air pollution on a range of cardiovascular events in England and Wales: case-crossover analysis of the MINAP database, hospital admissions and mortality
Conclusions This study found no clear evidence for pollution effects on STEMIs and stroke, which ultimately represent thrombogenic processes, though it did for pulmonary embolism. The strongest associations with air pollution were observed with selected non-MI outcomes.
Source: Heart - June 21, 2014 Category: Cardiology Authors: Milojevic, A., Wilkinson, P., Armstrong, B., Bhaskaran, K., Smeeth, L., Hajat, S. Tags: Open access, Drugs: cardiovascular system, Acute coronary syndromes, Venous thromboembolism, Epidemiology Cardiac risk factors and prevention Source Type: research

Using Drug-Intoxicated Deaths as Potential Organ Donors: Impression of Attendees at the American College of Medical Toxicology 2014 Annual Scientific Meeting.
CONCLUSIONS: Medical toxicologists have some reservation in recommending solid organs for transplantation from deaths from cocaine and carbon monoxide. Given the decrease in potential organ donors from typical methods of death, further work is needed to promote organ donation in deaths related to acute poisoning. PMID: 25023224 [PubMed - as supplied by publisher]
Source: Journal of Medical Toxicology - July 15, 2014 Category: Toxicology Authors: Wood DM, Chan WL, Dargan PI Tags: J Med Toxicol Source Type: research

Can air pollution trigger an onset of atrial fibrillation: a population-based study
This study aims to evaluate the effect of air pollution on the new AF onset requiring hospitalization. A case-crossover analysis was performed on a population of patients hospitalized in a large tertiary teaching hospital between 2006 and 2010 with first life occurrence of atrial fibrillation; 1458 patients were admitted to the hospital with new-onset AF. AF onset was associated with an interquartile range elevation of carbon monoxide concentrations during the winter season (odds ratio 1.15, p = 0.040) and sulfur dioxide concentrations during the fall season (odds ratio 1.21, p = 0.028). An interquartile range elev...
Source: Air Quality, Atmosphere and Health - September 14, 2014 Category: Environmental Health Source Type: research

The concentration of carbon monoxide in the breathing areas of workers during logging operations at the motor-manual level
Conclusions The risk increases along with conditions that generate the concentration of exhaust produced by 2-stroke petrol chainsaw engines.
Source: International Journal of Occupational Medicine and Environmental Health - September 12, 2014 Category: Occupational Health Source Type: research

Pure motor monoparesis of the leg after carbon monoxide intoxication
A woman in her late 40s with no medical history presented as comatose (Glasgow Coma Scale (GCS) score, 8) after a suicide attempt, where she inhaled the fumes of burning charcoal for approximately 4 h. On admission, her blood pressure was 108/70 mm Hg, and her heart rate was 118 bpm. Her carbon monoxide (CO)–haemoglobin concentration was 34%. Blood examinations did not show any evidence of drug overdose. Supportive mechanical ventilation was employed, and she became alert after 48 h. A physical examination revealed no abnormal findings except for left leg weakness, and a neurological examinat...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 17, 2014 Category: Neurosurgery Authors: Tajima, Y., Satoh, C., Yaguchi, H., Mito, Y. Tags: Coma and raised intracranial pressure, Neurological injury, Stroke, Trauma CNS / PNS, Hypertension, Unwanted effects / adverse reactions, Drugs misuse (including addiction), Suicide (psychiatry), Radiology, Adult intensive care, Mechanical ventilation, Me Source Type: research

Central and Peripheral Cardiovascular Impairments Limit V˙O2peak in Type 1 Diabetes
We examined the contribution of central and peripheral mechanisms to V˙O2peak in physically active adults with type 1 diabetes. Methods: Seven men with type 1 diabetes and 10 healthy age-, anthropometry-, and physical activity–matched men performed incremental cycling exercise until volitional fatigue. Alveolar gas exchange (turbine and mass spectrometry), cardiac function and systemic vascular resistance (impedance cardiography), and local active leg muscle deoxygenation and blood flow (near infrared spectroscopy) were monitored. Arterial–venous O2 difference was calculated (Fick principle). Blood volume (BV) (carbon...
Source: Medicine and Science in Sports and Exercise - January 20, 2015 Category: Sports Medicine Tags: Clinical Sciences Source Type: research