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Cancer: Nasopharyngeal Cancer

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Total 25 results found since Jan 2013.

Stroke death in patients receiving radiation for head and neck cancer in the modern era
ConclusionsWhile radiotherapy for head and neck cancer increases the hazard of stroke death, this is reduced in the modern era and remains a very small absolute risk.
Source: Frontiers in Oncology - June 15, 2023 Category: Cancer & Oncology Source Type: research

Accelerated Risk of Premature Ischemic Stroke in 5-Year Survivors of Nasopharyngeal Carcinoma.
CONCLUSION: Not only was the stroke risk in NPC survivors higher than that in the general population, but the onset age was also 10 years earlier. Future survivorship care should include ischemic stroke as a late complication, for its proper prevention and management. IMPLICATIONS FOR PRACTICE: Nasopharyngeal carcinoma (NPC) is endemic in Taiwan, and its 5-year survival is 65.2%. With the increased 5-year cancer survivors, survivorship has become an important issue. However, research on NPC survivorship is very rare. To the authors' knowledge, this is the first population-based study on long-term NPC survivors. This s...
Source: The Oncologist - March 20, 2019 Category: Cancer & Oncology Authors: Chen MC, Kuan FC, Huang SF, Lu CH, Chen PT, Huang CE, Wang TY, Chen CC, Lee KD Tags: Oncologist Source Type: research

Accelerated Risk of Premature Ischemic Stroke in 5‐Year Survivors of Nasopharyngeal Carcinoma
Conclusion.Not only was the stroke risk in NPC survivors higher than that in the general population, but the onset age was also 10 years earlier. Future survivorship care should include ischemic stroke as a late complication, for its proper prevention and management.Implications for Practice.Nasopharyngeal carcinoma (NPC) is endemic in Taiwan, and its 5‐year survival is 65.2%. With the increased 5‐year cancer survivors, survivorship has become an important issue. However, research on NPC survivorship is very rare. To the authors’ knowledge, this is the first population‐based study on long‐term NPC survivors. This...
Source: The Oncologist - September 10, 2019 Category: Cancer & Oncology Authors: Min-Chi Chen, Feng-Che Kuan, Shiang-Fu Huang, Chang-Hsien Lu, Ping-Tsung Chen, Cih-En Huang, Ting-Yao Wang, Chih-Cheng Chen, Kuan-Der Lee Tags: Head and Neck Cancers, Health Outcomes and Economics of Cancer Care Source Type: research

Is stroke incidence increased in survivors of adult cancers? A systematic review and meta-analysis
ConclusionsStroke incidence is significantly increased after diagnosis of certain cancers.Implications for Cancer SurvivorsCardiovascular risk should be assessed during cancer survivorship care, with attention to modifying shared cancer/cardiovascular risk factors.
Source: Journal of Cancer Survivorship - November 5, 2021 Category: Cancer & Oncology Source Type: research

Young nasopharyngeal cancer patients with radiotherapy and chemotherapy are most prone to ischaemic risk of stroke: a national database, controlled cohort study
ConclusionsPatients with nasopharyngeal carcinoma are at an elevated risk of ischaemic stroke, without significant difference among treatment modalities. The relative risk is more prominent in younger patients. Comorbidity may enhance the risk.
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Authors: Chu C.‐N., Chen P.‐C., Bai L.‐Y., Muo C.‐H., Sung F.‐C., Chen S.‐W. Tags: Original Article Source Type: research

Massive Epistaxis from Internal Carotid Pseudoaneurysm during Acute Ischemic Stroke in a Patient with Nasopharyngeal Carcinoma.
CONCLUSION: Carotid blowout syndrome in NPC patients during acute ischemic stroke warrants further cervical angiographic study. Endovascular treatment provides immediate hemostasis and obliteration of ICA pseudoaneurysm. PMID: 26077184 [PubMed - indexed for MEDLINE]
Source: Acta Neurologica Taiwanica - December 12, 2015 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Radiotherapy Induced Atherosclerosis and Stroke Syndrome (RIASS) Causing Bilateral Vision Loss and Multifocal Strokes. A Case Report and Literature Review (P4.358)
Conclusions: Evidence-based guidelines for the management of asymptomatic and symptomatic RIASS are lacking. We recommend periodic surveillance with carotid duplex scan for early diagnosis and implementation of effective stroke-prevention therapies. Most studies are retrospective surgical case series on patients with extracranial carotid stenosis (ECS) and favor either stenting or endarterectomy. Neither approach is clearly superior, as no head-to-head trial comparing both procedures in this context exists. Bypass surgery has been used in cases of HNXRT associated ECS but the long term effect has not been demonstrated. Aty...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rathore, J., Ali, M., Ulanski, L., Testai, F. Tags: Cerebrovascular Case Reports Source Type: research

Vertebral artery stenosis predicts cerebrovascular diseases following radiotherapy for nasopharyngeal carcinoma
CONCLUSION: Our study found that NPC patients with vertebral artery stenosis, atrial fibrillation, or hypertension carry a higher risk for ischemic stroke or TIA. Regular assessment of vertebral artery after radiotherapy was suggested.PMID:35357575 | DOI:10.1007/s00520-022-07011-8
Source: Atherosclerosis - March 31, 2022 Category: Cardiology Authors: Chien-Fu Yeh Yu-Ching Chin Wei Hung Pin-I Huang Ming-Ying Lan Source Type: research

A father ’s hope for his son’s life
Juan and Fredy in 2017. Juan was looking forward to having his son, Fredy, 14, finally come home to live with him. The teenager had been living under the care of his grandmother since he was a toddler. But on that long-awaited homecoming day, Juan was quickly jarred from feeling great joy to grave concern. “When I saw his face, one side looked very different from the other and his lip was swollen,” says Juan. “He admitted right away that his face had been hurting.” Juan remembered that the last time he’d seen his son — more than one year ago — Fredy’s face had looked slightly different then too. But whateve...
Source: Thrive, Children's Hospital Boston - April 12, 2017 Category: Pediatrics Authors: Kat J. McAlpine Tags: Diseases & Conditions Our Patients’ Stories Dr. Cameron Trenor Dr. Carolyn Rogers Dr. Darren Orbach Dr. Reza Rahbar Dr. Salim Afshar interventional radiology juvenile nasopharyngeal angiofibroma tumor Source Type: news

Bilateral thalamic and mesencephalic infarctions with hypopituitarism as long-term complications postradiotherapy: A case report
Conclusion: To our knowledge, this is the first report of bilateral thalamic and mesencephalic infarction together with hypopituitarism following radiotherapy for NPC.
Source: Medicine - August 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

A nomogram for the prediction of cerebrovascular disease among patients with brain necrosis after radiotherapy for nasopharyngeal carcinoma
In various cancer populations, radiotherapy is associated with the development of vascular disease [1 –4]. Previous studies have established an increased incidence of carotid stenosis (CAS) and ischemic stroke in patients with head and neck cancer treated with radiotherapy [4,5]. A study of 6862 patients (age>65  years) showed that five-year incidence of cerebrovascular events was 19% in patients treated with radiotherapy alone compared with 14% in patients treated with surgery plus radiotherapy; the corresponding ten-year incidence were 34% and 25%, respectively [4].
Source: Radiotherapy and Oncology - December 21, 2018 Category: Radiology Authors: Jinhua Cai, Jinping Cheng, Honghong Li, Wei-Jye Lin, Yi Li, Xiaohuang Zhuo, Xiaolong Huang, Charles B. Simone, Wilbert S. Aronow, Edward L.W. Chow, Yamei Tang Tags: Original Article Source Type: research

Long non-coding SNHG1 in cancer
ConclusionSNHG1 likely acts as a useful tumour biomarker for cancer diagnosis, prognosis and treatment.
Source: Clinica Chimica Acta - March 6, 2019 Category: Laboratory Medicine Source Type: research

Long non-coding SNHG1 in cancer.
CONCLUSION: SNHG1 likely acts as a useful tumour biomarker for cancer diagnosis, prognosis and treatment. PMID: 30849309 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Chemistry - March 4, 2019 Category: Chemistry Authors: Thin K, Tu JC, Sudheesh C Tags: Clin Chim Acta Source Type: research

Pentraxin 3 in Cardiovascular Disease
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1 1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy 2Humanitas Clinical and Research Center-IRCCS, Milan, Italy 3Humanitas University, Milan, Italy 4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research