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Total 19 results found since Jan 2013.

Using Aspirin Every Day May Cause Anemia in Seniors
A new study suggests regular aspirin use in older adults may pose a serious risk of anemia, adding to existing research that challenges the long-established recommendation to use aspirin as a preventative therapy for dangerous cardiac events. The results come just a year after a national independent task force updated formal recommendations in April 2022 cautioning those over the age of 60 against beginning a daily aspirin regimen. For decades, aspirin has been used like a vitamin by a sizable portion of America’s aging population. Research as far back as the 1950s showed a daily low dose of the anti-inflammatory me...
Source: TIME: Health - June 21, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized Aging healthscienceclimate Source Type: news

CO33 Methodological Challenges and Considerations for Decision Makers When Assessing within-Class Comparative Effectiveness and Cost-Effectiveness: The Case of Non-Vitamin K Antagonist Oral Anticoagulants
The United Kingdom National Institute of Health Care Excellence (NICE) published a draft clinical guideline for consultation on anticoagulation therapy for stroke prevention in individuals with atrial fibrillation in September 2020 that addressed which non-vitamin K antagonist oral anticoagulant (NOAC) therapy (apixaban, dabigatran, rivaroxaban, edoxaban) is most clinically and cost-effective. We aimed to elucidate methodological considerations and challenges involved in evaluating the comparative effectiveness and cost-effectiveness of within-class treatments for the  purpose of decision making by a reimbursement authority.
Source: Value in Health - June 26, 2022 Category: International Medicine & Public Health Authors: A Briggs, A Howarth, S Davies, J Schneider, G Spentzouris, F Mughal, A Fuat, M Fay Source Type: research

What the Science Says About the Health Benefits of Vitamins and Supplements
From multivitamins and melatonin to fiber and fish oil, Americans who are trying to boost their health and immunity have a plethora of supplements to choose from. An estimated 58% of U.S. adults ages 20 and over take dietary supplements, according to the U.S. Centers for Disease Control and Prevention, and the supplement industry is valued at more than $30 billion a year. Supplement use has been growing rapidly over the past few decades along with the wellness industry. “The popular belief is that a supplement is going to be helpful for promoting health,” says Fang Fang Zhang, a professor at Tufts University&rs...
Source: TIME: Health - April 28, 2022 Category: Consumer Health News Authors: Sandeep Ravindran Tags: Uncategorized Diet & Nutrition healthscienceclimate Source Type: news

Stroke severity in patients with preceding direct oral anticoagulant therapy as compared to vitamin K antagonists
AbstractBackgroundAlthough direct oral anticoagulants (DOAC) have proven at least equally effective in the prevention of acute ischemic stroke (AIS) in patients with atrial fibrillation as compared to the vitamin K antagonists (VKA), no reliable data on the severity of AIS of DOAC patients as compared to VKA is available.MethodsUsing a prospectively collected cohort of AIS patients, we performed univariate and multivariate (displayed as adjusted Odds Ratios, OR and 95% confidence intervals, 95% CI) analyses regarding the severity of AIS in patients with preceding DOAC (N = 210) versus VKA (N = 173) therapy. Additio...
Source: Journal of Neurology - June 3, 2019 Category: Neurology Source Type: research

Neuroimaging and clinical outcomes of oral anticoagulant –associated intracerebral hemorrhage
ObjectiveWhether intracerebral hemorrhage (ICH) associated with non –vitamin K antagonist oral anticoagulants (NOAC‐ICH) has a better outcome compared to ICH associated with vitamin K antagonists (VKA‐ICH) is uncertain.MethodsWe performed a systematic review and individual patient data meta ‐analysis of cohort studies comparing clinical and radiological outcomes between NOAC‐ICH and VKA‐ICH patients. The primary outcome measure was 30‐day all‐cause mortality. All outcomes were assessed in multivariate regression analyses adjusted for age, sex, ICH location, and intraventricul ar hemorrhage extension.Results...
Source: Annals of Neurology - October 25, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Duncan Wilson, Aristeidis H. Katsanos, Jo ão Sargento‐Freitas, Cláudia Marques‐Matos, Elsa Azevedo, Tomohide Adachi, Christian Brelie, Yoshifusa Aizawa, Hiroshi Abe, Hirofumi Tomita, Ken Okumura, Joji Hagii, David J Tags: Research Article Source Type: research

Serum 25-hydroxyvitamin D deficiency predicts poor outcome among acute ischemic stroke patients without hypertension
Publication date: Available online 3 May 2018Source: Neurochemistry InternationalAuthor(s): Bingjun Zhang, Yuge Wang, Yi Zhong, Siyuan Liao, Zhengqi LuAbstract25-Hydroxyvitamin D (25(OH)D) deficiency is a frequent condition in patients who suffer acute ischemic stroke (AIS), and several studies suggested that it may be associated with a poorer prognosis. Whether this association is affected by hypertension is unclear. Our aim was to investigate the association between 25(OH)D levels and both clinical severity and outcome after 3 months in AIS patients stratified by the history of hypertension. Consecutive first-ever AIS pa...
Source: Neurochemistry International - July 10, 2018 Category: Neuroscience Source Type: research

Continuation or Discontinuation of Anticoagulation in the Early Phase After Acute Ischemic Stroke Brief Report
Background and Purpose—There is no consensus on whether anticoagulation should be continued or temporarily stopped in patients suffering acute ischemic stroke while using anticoagulation. We assessed treatment variations and outcomes in these patients.Methods—Post hoc analysis of PASS (Preventive Antibiotics in Stroke Study). We included patients with acute ischemic stroke who used anticoagulation at admission. We compared clinical outcomes, thrombotic, and major bleeding events at 3 months.Results—Nine percent (192/2101) of the patients with acute ischemic stroke used anticoagulation at admission (186 vitamin K anta...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Adrien E. Groot, Jan-Dirk M. Vermeij, Willeke F. Westendorp, Paul J. Nederkoorn, Diederik van de Beek, Jonathan M. Coutinho Tags: Secondary Prevention, Anticoagulants, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Serum 25-hydroxyvitamin D deficiency predicts poor outcome among acute ischemic stroke patients without hypertension
Publication date: Available online 3 May 2018 Source:Neurochemistry International Author(s): Bingjun Zhang, Yuge Wang, Yi Zhong, Siyuan Liao, Zhengqi Lu 25-Hydroxyvitamin D (25(OH)D) deficiency is a frequent condition in patients who suffer acute ischemic stroke (AIS), and several studies suggested that it may be associated with a poorer prognosis. Whether this association is affected by hypertension is unclear. Our aim was to investigate the association between 25(OH)D levels and both clinical severity and outcome after 3 months in AIS patients stratified by the history of hypertension. Consecutive first-ever AIS patient...
Source: Neurochemistry International - May 3, 2018 Category: Neuroscience Source Type: research

Non-Vitamin K Oral Anticoagulants (NOACs) and Their Reversal
AbstractPurpose of ReviewAn 80-year-old man presents with an acute right hemiparesis and National Institutes of Health Stroke Scale (NIHSS) of 25, 14  h after taking dabigatran. Activated partial thromboplastin time (aPTT) is 42.8 s. Arteriogram demonstrates left internal carotid artery thrombosis. What is the appropriate management of this patient with acute ischemic stroke while on a NOAC?Recent FindingsIdarucizumab is a reversal agent approved for dabigatran, and two more reversal agents, andexanet alfa and aripazine, are currently in development for NOACs.SummaryIn this article, we review currently available NOACs, t...
Source: Current Neurology and Neuroscience Reports - July 22, 2017 Category: Neuroscience Source Type: research

Moringa's Health Benefits In Lowering Inflammation
Copyright: Brenda Dawson/UC Davis Moringa is known throughout the world as a miracle tree. But, what exactly is moringa and why is research buzzing about the possible health benefits of this hearty plant? Moringa is a tree that is an important crop native to India and currently grown throughout the world in Latin America, Southeast Asia and Africa. The entire tree is edible, from its roots, flowers, leaves, seeds, gum, fruits and bark. Generally, moringa is consumed by cooking the leaves or immature fruits and more recently as a dried leaf powder used as tea or sprinkled into food. Although 13 species exist in the morin...
Source: Healthy Living - The Huffington Post - July 13, 2016 Category: Consumer Health News Source Type: news

Use of the Direct Oral Anticoagulants in Obese Patients: guidance from the SSC of the ISTH
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - February 29, 2016 Category: Hematology Authors: K Martin, J Beyer‐Westendorf, BL Davidson, MV Huisman, PM Sandset, S Moll Tags: Recommendations and Guidelines Source Type: research

Visceral Fat Triggers Heart Disease
I tell my patients to avoid drinking soda not just because they make you fat. Each sip of soda affects your health. Soda puts you at risk for health problems like metabolic syndrome. This is a collection of symptoms that can lead to diabetes, heart disease and other chronic diseases, like cancer. Soft drinks are the beverage of choice for millions of Americans. The latest research now reveals that sodas are a major cause of visceral fat — the deadliest kind of fat you can have, inflaming your tissues, rotting your blood vessels and upsetting your body chemistry. In a minute I’m going to tell you about a great healthy ...
Source: Al Sears, MD Natural Remedies - February 29, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health heart disease metabolic syndrome Visceral Fat Source Type: news

New Cholesterol Vaccine Shows Promise, But Don't Eat Extra Bacon Just Yet
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Source: Science - The Huffington Post - November 12, 2015 Category: Science Source Type: news