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Nutrition: Sodium
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Total 1017 results found since Jan 2013.
Clinical Efficacy and Short-Term Prognosis of Butylphthalide and Sodium Chloride Injection Compared to Edaravone in the Treatment of Patients with Acute Stroke
CONCLUSIONS: This study highlights the positive impact of butylphthalide and edaravone on the therapeutic effect and short-term prognosis in acute stroke patients. The findings provide valuable guidance for future research and enhance our understanding of these drugs' mechanisms, offering the potential for improved stroke management and patient outcomes.PMID:37499159
Source: Alternative Therapies in Health and Medicine - July 27, 2023 Category: Complementary Medicine Authors: Dan Yang Mi Zhang Xiaoyan Wang Jianna Zhang Source Type: research
Burden and attributable risk factors of ischemic stroke in China from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019
ConclusionOur study revealed that great changes have occurred in burden and attributable risk factors of ischemic stroke in China in the past three decades. Distinct sex-specific differences are observed in burden and attributable risk factors.
Source: Frontiers in Neurology - July 26, 2023 Category: Neurology Source Type: research
Comparative Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations : A General Population Cohort Study
CONCLUSION: Among patients with gout, SGLT2is may reduce recurrent flares and gout-primary ED visits and hospitalizations and may provide cardiovascular benefits.PRIMARY FUNDING SOURCE: National Institute of Arthritis and Musculoskeletal and Skin Diseases.PMID:37487215 | DOI:10.7326/M23-0724
Source: Annals of Internal Medicine - July 24, 2023 Category: Internal Medicine Authors: Natalie McCormick Chio Yokose Jie Wei Na Lu Deborah J Wexler J Antonio Avi ña-Zubieta Mary A De Vera Yuqing Zhang Hyon K Choi Source Type: research
Differential Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Cardiovascular and Renal Outcomes According to Renal Function: A Dose-Response Meta-Analysis Involving 10 Randomized Clinical Trials and 71,553 Individuals
CONCLUSION: The protective effects of SGLT2i for reducing most adverse cardiovascular and renal outcomes persisted in patients with variable degrees of renal impairment. The observed benefits such as preventing CV death, HF worsening, or stroke may be greater for patients with more severe CKD. Considering the cardiovascular and renal benefits associated with SGLT2i treatment, patients with CKD should be treated aggressively to improve outcomes.PROSPERO REGISTRATION NUMBER: CRD42021273500.PMID:37474112 | DOI:10.1093/ejendo/lvad078
Source: European Journal of Endocrinology - July 20, 2023 Category: Endocrinology Authors: Donna Shu-Han Lin An-Li Yu Hao-Yun Lo Cheng-Wei Lien Jen-Kuang Lee Fu-Tien Chiang Yu-Kang Tu Source Type: research
How to Tell The Difference Between Heat Stress, Exhaustion, and Stroke
The terminology around heat injuries and illness is often confusing. As extreme heat warnings sweep the U.S., here is what you need to know about heat stress, heat exhaustion, and heat stroke.
A 90°F-day might be perfect for the beach. But once you start working your body, whether it’s mowing the lawn, going for a hike, or sprinting to catch the bus, your metabolism ramps up, burning fuel and raising your body’s core temperature. Your heart compensates by pumping blood away from your overheated organs to your skin, where dilating blood vessels can dissipate the heat with the help of evaporating sweat. If yo...
Source: TIME: Health - July 18, 2023 Category: Consumer Health News Authors: Aryn Baker Tags: Uncategorized Climate Is Everything Explainer extreme weather healthscienceclimate Source Type: news
TNF- α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor
In conclusion, specific inhibition of Rho kinase in cerebrovascular conditions, accompanied by excessive release of pro-inflammatory cytokine TNF-α, helps preserve endothelial cell morphology and inter-endothelial cell barrier formation and may serve as an important therapeutic target.PMID:37454559 | DOI:10.1016/j.imbio.2023.152706
Source: Immunobiology - July 16, 2023 Category: Allergy & Immunology Authors: Xin Gao Ulvi Bayraktutan Source Type: research
Risk of New-onset Stroke in Patients with Type 2 Diabetes with Chronic Kidney Disease on Sodium-glucose Co-transporter-2 Inhibitor Users
This study aimed to examine the association between the use of SGLT2 inhibitors and NOS risk in patients with T2D and CKD. We conducted a nationwide retrospective cohort study using data from the Taiwan Health Insurance Review and Assessment Service database for the years 2004 to 2019. The primary outcome was the risk of incident stroke, which was estimated using hazard ratios (HRs) and 95% confidence intervals (CIs). We used multiple Cox regression modeling to analyze the association between SGLT2 inhibitor use and the risk of stroke in patients with T2D and CKD. In a cohort of 113,710 patients with T2D and CKD who were u...
Source: Translational Stroke Research - July 14, 2023 Category: Neurology Source Type: research
Blood pressure-lowering effects of SGLT2 inhibitors and GLP-1 receptor agonists for preventing of cardiovascular events and death in type 2 diabetes: a systematic review and meta-analysis
ConclusionIn patients with type 2 diabetes, the hypotensive effects of SGLT2i and GLP-1 RAs were significantly associated with a reduction in mortality and cardiorenal events. These findings suggest that the lowering BP effect could be seen as an additive indicator of cardiovascular protection by SGLT2i and GLP-1 RAs drugs.
Source: Acta Diabetologica - July 13, 2023 Category: Endocrinology Source Type: research
Sodium Tanshinone IIA Sulfonate Ameliorates Oxygen-glucose Deprivation/Reoxygenation-induced Neuronal Injury via Protection of Mitochondria and Promotion of Autophagy
Neurochem Res. 2023 Jul 12. doi: 10.1007/s11064-023-03985-x. Online ahead of print.ABSTRACTSodium tanshinone IIA sulfonate (STS) has shown significant clinical therapeutic effects in cerebral ischemic stroke (CIS), but the molecular mechanisms of neuroprotection remain partially known. The purpose of this study was to explore whether STS plays a protective role in oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by regulating microglia autophagy and inflammatory activity. Co-cultured microglia and neurons were subjected to OGD/R injury, an in vitro model of ischemia/reperfusion (I/R) injury with or ...
Source: Neurochemical Research - July 12, 2023 Category: Neuroscience Authors: Zhi Ma Yue Wu Juan Xu Hui Cao Mingyang Du Haibo Jiang Feng Qiu Source Type: research
