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Nutrition: Omega 3
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Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease.
CONCLUSIONS: This is the most extensive systematic review of RCTs conducted to date to assess effects of increasing PUFA on cardiovascular disease, mortality, lipids or adiposity. Increasing PUFA intake probably slightly reduces risk of coronary heart disease and cardiovascular disease events, may slightly reduce risk of coronary heart disease mortality and stroke (though not ruling out harms), but has little or no effect on all-cause or cardiovascular disease mortality. The mechanism may be via TG reduction.
PMID: 30484282 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - November 27, 2018 Category: General Medicine Authors: Abdelhamid AS, Martin N, Bridges C, Brainard JS, Wang X, Brown TJ, Hanson S, Jimoh OF, Ajabnoor SM, Deane KH, Song F, Hooper L Tags: Cochrane Database Syst Rev Source Type: research
Effects of fatty and lean fish intake on stroke risk: a meta-analysis of prospective cohort studies
Fish intake has been postulated to reduce the risk of stroke. However, whether the beneficial effect of fish are mainly linked to fat content, as a source of omega-3 polyunsaturated fatty acids, remains unclea...
Source: Lipids in Health and Disease - November 23, 2018 Category: Lipidology Authors: Zhi-Zhen Qin, Jia-Ying Xu, Guo-Chong Chen, Yu-Xia Ma and Li-Qiang Qin Tags: Research Source Type: research
New Studies Give Mixed Results About Taking Fish Oil and Vitamin D
(CHICAGO) — Taking fish oil or vitamin D? Big studies give long-awaited answers on who does and does not benefit from these popular nutrients.
Fish oil taken by healthy people, at a dose found in many supplements, showed no clear ability to lower heart or cancer risks. Same for vitamin D.
But higher amounts of a purified, prescription fish oil slashed heart problems and heart-related deaths among people with high triglycerides, a type of fat in the blood, and other risks for heart disease. Doctors cheered the results and said they could suggest a new treatment option for hundreds of thousands of patients like these.
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Source: TIME: Health - November 10, 2018 Category: Consumer Health News Authors: MARILYNN MARCHIONE / AP Tags: Uncategorized onetime Supplements Source Type: news
Prescription Doses of Fish Oil May Lower Heart Attack and Stroke Risk
Omega-3 fatty acids, abundant in fish oil, are known to be good for the heart. Studies have shown that people who eat more fish rich in these fats have lower rates of heart problems and less risk of dying from heart disease compared to those who eat less. Those data have fueled a booming business in over-the-counter fish oil supplements.
In a new study published in the New England Journal of Medicine, and presented at the American Heart Association annual meeting, researchers report that a highly purified version of omega-3 fats, called icosapent ethyl, can lower the risk of a number of heart-related events, including hear...
Source: TIME: Health - November 10, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthytime Heart Disease omega-3 Source Type: news
Fish Oil and Vitamin D Supplements May Not Help Prevent Heart Attacks and Cancer, Study Says
There’s good evidence that fish oil supplements may lower the risk of second heart events — like a heart attack or stroke — in people with heart disease, but few rigorous studies have investigated whether the supplement can help people to lower their risk of having a heart event in the first place. And while some data suggests that people with lower levels of vitamin D tend to have higher rates of heart disease and cancer, the evidence isn’t solid.
Now, a new study published in the New England Journal of Medicine and presented at the annual meeting of the American Heart Association offers more findi...
Source: TIME: Health - November 10, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs Source Type: news
Vitamin D and Fish Oils Are Ineffective for Preventing Cancer and Heart Disease
The largest study to test vitamin D and omega-3 pills in healthy adults found they did little to prevent cardiovascular disease, but hinted at benefits for groups including African-Americans.
Source: NYT Health - November 10, 2018 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Cancer Heart Stroke Dietary Supplements and Herbal Remedies Vitamin D Omega-3 Fatty Acids Vitamins Fish and Other Marine Life Preventive Medicine Deaths (Fatalities) Source Type: news
VITAL study: How vitamin D and fish oil affect risk of heart attack, stroke and cancer
(Brigham and Women's Hospital) Brigham and Women's Hospital investigators leading the VITamin D and OmegA-3 TriaL (VITAL) conducted a rigorous placebo-controlled trial over the course of 5.3 years, gleaning a treasure trove of information on the effects of both supplements.
Source: EurekAlert! - Cancer - November 10, 2018 Category: Cancer & Oncology Source Type: news
Docosanoids and elovanoids from omega-3 fatty acids are pro-homeostatic modulators of inflammatory responses, cell damage and neuroprotection
We present an overview of how a) NPD1 selectively mediates preconditioning rescue of RPE and PR cells; b) NPD1 restores aberrant neuronal networks in experimental epileptogenesis; c) the decreased ability to biosynthesize NPD1 in memory hippocampal areas of early stages of Alzheimer's disease takes place; d) NPD1 protection of dopaminergic circuits in an in vitro model using neurotoxins; and e) bioactivity elicited by DHA and NPD1 activate a neuroprotective gene-expression program that includes the expression of Bcl-2 family members affected by Aβ42, DHA, or NPD1. In addition, we highlight ELOVL4 (ELOngation of Very Long ...
Source: Molecular Aspects of Medicine - October 5, 2018 Category: Molecular Biology Source Type: research
Regulation of platelet function and thrombosis by omega-3 and omega-6 polyunsaturated fatty acids
Publication date: November 2018Source: Prostaglandins & Other Lipid Mediators, Volume 139Author(s): Reheman Adili, Megan Hawley, Michael HolinstatAbstractThrombosis is the most common underlying pathology responsible for morbidity and mortality in cardiovascular disease (CVD). Platelet adhesion, activation, and aggregation play central roles in hemostasis; however, the same process may also cause thrombosis and vessel occlusion at the site of ruptured atherosclerotic lesions leading to heart attack and stroke. ω-3 and ω-6 polyunsaturated fatty acids (PUFAs) are an essential component of the platelet phospholipid membrane...
Source: Prostaglandins and Other Lipid Mediators - October 4, 2018 Category: Lipidology Source Type: research
Fish Oil Drug May Reduce Heart Attack and Stroke Risks for Some
Large doses of an omega-3 fatty acid in fish oil sharply reduced the rate of cardiovascular events in people with a history of heart disease or Type 2 diabetes.
Source: NYT Health - September 25, 2018 Category: Consumer Health News Authors: ANAHAD O ’ CONNOR Tags: Heart Omega-3 Fatty Acids Diabetes Statins (Cholesterol-Lowering Drugs) Amarin Corp PLC Source Type: news
Post-stroke administration of omega-3 polyunsaturated fatty acids promotes neurovascular restoration after ischemic stroke in mice: Efficacy declines with aging.
Abstract
Post-stroke treatment with omega-3 polyunsaturated fatty acids (n-3 PUFAs) may be a promising therapy in young animals but this has not been tested in aged subjects, a population at most risk of ischemic stroke. Herein we examined the therapeutic efficacy of n-3 PUFAs after distal middle cerebral artery occlusion (dMCAO) in young (10-12 weeks old) and aged (18 months old) mice. Post-ischemic mice were randomly assigned to 4 groups that received: 1) regular food with low content of n-3 PUFAs, 2) intraperitoneal docosahexaenoic acid (DHA, a major component of n-3 PUFAs) injections, 3) Fish oil (FO, cont...
Source: Neurobiology of Disease - September 12, 2018 Category: Neurology Authors: Jiang X, Suenaga J, Pu H, Wei Z, Smith AD, Hu X, Shi Y, Chen J Tags: Neurobiol Dis Source Type: research
Omega-3 supplements do not protect against cardiovascular disease, meta-analysis shows
A meta-analysis of 79 trials showed that increasing long-chain omega-3 had little or no effect on death from all causes, cardiovascular deaths, cardiovascular events, coronary heart disease deaths, stroke or arrhythmia.
Source: Clinical Pharmacist - August 31, 2018 Category: Drugs & Pharmacology Source Type: research
Studies: Low-Dose Aspirin May Not Prevent Initial Heart Attack, Stroke
Taking a low-dose aspirin every day has long been known to cut the chances of another heart attack, stroke or other heart problem in people who already have had one, but the risks don’t outweigh the benefits for most other folks, major new research finds.
Although it’s been used for more than a century, aspirin’s value in many situations is still unclear. The latest studies are some of the largest and longest to test this pennies-a-day blood thinner in people who don’t yet have heart disease or a blood vessel-related problem.
One found that aspirin did not help prevent first strokes or heart attacks...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 27, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch aspirin Source Type: news
New research shows little effect of omega 3 on risk of heart disease, stroke or death
(Wiley) Omega 3 is a type of fat. Small amounts of omega 3 fats are essential for good health, and they can be found in the food that we eat.
Source: EurekAlert! - Medicine and Health - July 18, 2018 Category: International Medicine & Public Health Source Type: news
Media coverage of new Cochrane Review of Cochrane Review on omega-3 fatty acids
New evidence published today shows there is little or no effect of omega 3 supplements on our risk of experiencing heart disease, stroke or death. Below is a round-up for some of the media coverage.Fishy findings: Cochrane review finds omega-3 supplements don ' t help heartsonScimexOmega 3 supplements do not reduce risk of heart disease, stroke, or death, finds review onthe bmjOmega-3 pills and fish oil ‘useless’ for preventing diseaseonThe Times IT ' S OIL A MYTH Omega-3 and fish extracts don ’t help your heart health, researchers claim onThe SunFish oil for a healthy heart ' nonsense 'on BBC News‘Better spending...
Source: Cochrane News and Events - July 18, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news
