Triple targeted therapy for advanced bowel cancer improves survival
Patients with metastatic colorectal cancer who have a BRAF mutation have improved survival after treatment with three targeted therapies instead of standard chemotherapy, results from a phase III trial have shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - August 23, 2019 Category: Drugs & Pharmacology Source Type: research

Evaluating the first NHS-funded sore throat test and treat service in the UK
In Wales, people with a sore throat may be offered advice and symptomatic treatment free of charge in community pharmacies through the common ailment service (CAS). However, antibiotics cannot be supplied and this can limit patients ’ perceived value of the service. As a result, some patients continue to seek a GP appointment when they have a sore throat. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - August 14, 2019 Category: Drugs & Pharmacology Source Type: research

Pharmacists must embrace pharmacogenetic services before other professions beat them to it
Multidisciplinary genetic testing services will help patients receive more targeted medicines, and pharmacists are the obvious healthcare professional to lead them. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - August 14, 2019 Category: Drugs & Pharmacology Source Type: research

Pain or insomnia main reasons for cannabis use in those without medical certificate
Customers who buy cannabis from “adult use” dispensaries, where no medical certificate is required, commonly report that they use it for pain relief or to help them sleep. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - August 6, 2019 Category: Drugs & Pharmacology Source Type: research

Most antidepressants reduce mortality for patients with diabetes and depression
Use of certain antidepressants to treat depression in patients with diabetes is associated with a reduction in mortality, according to a population-based study. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - August 2, 2019 Category: Drugs & Pharmacology Source Type: research

Low vitamin D status in early life linked to future high blood pressure
Children with persistently low plasma vitamin D levels at birth and in early childhood have an increased risk of elevated systolic blood pressure later in childhood, research has suggested. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 30, 2019 Category: Drugs & Pharmacology Source Type: research

Efficacy of tramadol reduced by concurrent use of some antidepressants
Taking certain antidepressants reduces the efficacy of the opioid medicine tramadol, according to research published in  Pharmacotherapy. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 26, 2019 Category: Drugs & Pharmacology Source Type: research

Statin treatment associated with reduced risk of glaucoma
Receiving statin treatment for five years or more is associated with a 21% reduced risk of primary glaucoma, research has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 23, 2019 Category: Drugs & Pharmacology Source Type: research

Heart failure, older people and frailty
Diagnosis of heart failure and frailty can often be masked by other long-term conditions, making the delivery of treatment goals complicated. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 12, 2019 Category: Drugs & Pharmacology Source Type: research

SGLT2 inhibitor lowers risk of kidney failure in type 2 diabetes
Patients with type 2 diabetes mellitus and chronic kidney disease have a lower risk of kidney failure and cardiovascular events if they are treated with canagliflozin, research has confirmed. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 11, 2019 Category: Drugs & Pharmacology Source Type: research

Testosterone deficiency: diagnosis, assessment and treatment
Male hypogonadism can significantly affect health and quality of life; however, diagnosis and management can be challenging. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 10, 2019 Category: Drugs & Pharmacology Source Type: research

Taking an STP approach to improving the pharmacy workforce
Developing a sustainable, high quality pharmacy workforce is essential to delivering services in a complex and evolving healthcare environment, particularly as more opportunities arise for pharmacists to take extended roles. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 10, 2019 Category: Drugs & Pharmacology Source Type: research

Pharmacists must work with others to roll back polypharmacy culture
The new English Desprescribing Network will bring together healthcare professionals and researchers to stamp out medicine-related harm. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 9, 2019 Category: Drugs & Pharmacology Source Type: research

App helps patients cut opioid use after knee replacement
Patients who underwent knee replacement who used an app to monitor their  analgesic use had better pain control and took fewer opioids post surgery, study results show. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 8, 2019 Category: Drugs & Pharmacology Source Type: research

Concerns raised over non-medical alprazolam use
The benzodiazepine alprazolam is being obtained for non-medical use in the UK, particularly among young people, a survey has found. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - July 5, 2019 Category: Drugs & Pharmacology Source Type: research