Filtered By:
Nutrition: Magnesium

This page shows you your search results in order of date. This is page number 11.

Order by Relevance | Date

Total 161 results found since Jan 2013.

Plasma Magnesium and Risk of Ischemic Stroke Among Women Clinical Sciences
Conclusions— Lower plasma magnesium levels may contribute to higher risk of ischemic stroke among women.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Akarolo-Anthony, S. N., Jimenez, M. C., Chiuve, S. E., Spiegelman, D., Willett, W. C., Rexrode, K. M. Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

The BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity
Background: Preterm birth is the leading cause of infant mortality globally, including Brazil. We will evaluate whether oral magnesium citrate reduces the risk of placental dysfunction and its negative consequences for both the fetus and mother, which, in turn, should reduce the need for indicated preterm delivery. Methods: We will complete a multicenter, randomized double-blind clinical trial comparing oral magnesium citrate 150 mg twice daily (n = 2000 women) to matched placebo (n = 1000 women), starting at 121/7 to 206/7 weeks gestation and continued until delivery. We will include women at higher risk for placental dys...
Source: BMC Pregnancy and Childbirth - Latest articles - July 8, 2014 Category: OBGYN Authors: Joao AlvesCarla de AraújoIsabelle PontesAngélica GuimarãesJoel Ray Source Type: research

Intakes of Potassium, Magnesium, and Calcium and Risk of Stroke Brief Reports
Conclusions— This study supports an association between high magnesium intake and a reduced stroke risk.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Sluijs, I., Czernichow, S., Beulens, J. W. J., Boer, J. M. A., van der Schouw, Y. T., Verschuren, W. M. M., Grobbee, D. E. Tags: Epidemiology Brief Reports Source Type: research

Magnesium in Stroke: Does It Reduce Disability?Magnesium in Stroke: Does It Reduce Disability?
Dr. Mark Alberts discusses results of the FAST-MAG trial looking at whether field administration of magnesium reduces long-term disability in stroke. Medscape Neurology
Source: Medscape Neurology and Neurosurgery Headlines - February 28, 2014 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news

Quick magnesium treatment fails to improve stroke outcomes, but study has silver lining
In the first study of its kind, a consortium led by UCLA physicians found that giving stroke patients intravenous magnesium within an hour of the onset of symptoms does not improve stroke outcomes.   However, the 8-year trial did find that with the help of paramedics in the field, intravenous medications can frequently be administered to stroke victims within that so-called "golden hour," during which they have the best chance to survive and avoid debilitating, long-term neurological damage.   The latter finding is a "game-changer," said Dr. Jeffrey Saver, director of the UCLA Stroke Center and a professor of ...
Source: UCLA Newsroom: Health Sciences - February 13, 2014 Category: Universities & Medical Training Source Type: news

Methodology of the Field Administration of Stroke Therapy – Magnesium (FAST‐MAG) phase 3 trial: Part 1 – rationale and general methods
RationalePrehospital initiation by paramedics may enable delivery of neuroprotective therapies to stroke patients in the hyperacute period when they are most effective in preclinical studies. Magnesium is neuroprotective in experimental stroke models and has been shown to be safe with signals of potential efficacy when started early after onset of human cerebral ischemia. Aims(a) To demonstrate that paramedic initiation of the neuroprotective agent magnesium sulfate in the field is an efficacious and safe treatment for acute stroke; (b) To demonstrate that field enrollment of acute stroke patients is a practical and feasib...
Source: International Journal of Stroke - January 1, 2014 Category: Neurology Authors: Jeffrey L. Saver, Sidney Starkman, Marc Eckstein, Samuel Stratton, Frank Pratt, Scott Hamilton, Robin Conwit, David S. Liebeskind, Gene Sung, Nerses Sanossian, Tags: Protocols Source Type: research

Intraoperative Magnesium Administration Does Not Improve Neurocognitive Function After Cardiac Surgery Clinical Sciences
Conclusions— Magnesium administered intravenously during cardiac surgery does not reduce postoperative cognitive dysfunction. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00041392.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Mathew, J. P., White, W. D., Schinderle, D. B., Podgoreanu, M. V., Berger, M., Milano, C. A., Laskowitz, D. T., Stafford-Smith, M., Blumenthal, J. A., Newman, M. F., for the Neurologic Outcome Research Group (NORG) of The Duke Heart Center, Neurologic Out Tags: Clinical Sciences Source Type: research

The high heart health value of drinking-water magnesium
Abstract: Universal drinking water and beverages containing moderate to high levels of magnesium (10–100ppm) could potentially prevent 4.5million heart disease and stroke deaths per year, worldwide. This potential is calculated with 2010 global mortality figures combined with a recent quantification of water-magnesium’s inverse association with heart disease and stroke mortality. The modern processed food diet, low in magnesium and spreading globally, makes this well-researched potential of drinking-water magnesium worth serious consideration, especially in areas where insufficient dietary intake of magnesium is prevalent.
Source: Medical Hypotheses - October 28, 2013 Category: Biomedical Science Authors: Andrea Rosanoff Tags: Articles Source Type: research

Acute Decrease in Serum Magnesium Level after Ischemic Stroke May Not Predict Decrease in Neurologic Function
Conclusions: Our results suggest that patients who have low Mg(2+) at baseline or a reduction in Mg(2+) 24 hours after admission are not at a higher risk of experiencing ND or poor short-term outcome. Ongoing prospective interventional trials will determine if hyperacute aggressive magnesium replacement affords neuroprotection in stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2013 Category: Neurology Authors: James E. Siegler, Amelia K. Boehme, Karen C. Albright, Sami Bdeir, Anoop K. Kar, Leann Myers, T. Mark Beasley, Sheryl Martin-Schild Tags: Original Articles Source Type: research

FAST-Mag protocol with or without mild hypothermia (35̊C) does not improve outcome after permanent MCAO in rats.
Abstract The current study assessed the neuroprotective efficacy of magnesium using a FAST-Mag trial treatment protocol alone, and in combination with mild hypothermia, in Sprague Dawley rats subjected to permanent, middle cerebral artery occlusion (MCAO). Treatment with magnesium (MgSO4.7H2O) consisted of an intravenous loading dose (LD: 360 μmol/kg) and a 24 hour infusion (120 μmol/kg/h), while mild hypothermia at 35̊C was maintained for 24 hours. Treatment groups consisted of animals receiving: i) saline; ii) magnesium LD/infusion at 1.5 h/2.5 h post-MCAO; iii) magnesium LD/infusion at 1.5 h/2.5 h post-...
Source: Magnesium Research - June 28, 2013 Category: Biochemistry Authors: Meloni BP, Cross JL, Brookes LM, Clark VW, Campbell K, Knuckey NW Tags: Magnes Res Source Type: research

Magnesium treatment for neuroprotection in ischemic diseases of the brain
This article reviews experimental and clinical data on the use of magnesium as a neuroprotective agent in various conditions of cerebral ischemia. Whereas magnesium has shown neuroprotective properties in animal models of global and focal cerebral ischemia, this effect could not be reproduced in a large human stroke trial. These conflicting results may be explained by the timing of treatment. While treatment can be started before or early after ischemia in experimental studies, there is an inevitable delay of treatment in human stroke. Magnesium administration to women at risk for preterm birth has been investigated in sev...
Source: Experimental and Translational Stroke Medicine - April 25, 2013 Category: Neurology Source Type: research