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Nutrition: Calcium

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Total 218 results found since Jan 2013.

The relationship between bone mineral density and cerebral pulsatility index in patients with acute ischemic stroke (P6.025)
Conclusions: Our findings indicate that decreased BMD may be associated with atherosclerosis in the cerebral circulation.Disclosure: Dr. Park has nothing to disclose. Dr. Park has nothing to disclose. Dr. Suk has nothing to disclose. Dr. Koh has nothing to disclose. Dr. Hwang has nothing to disclose. Dr. Song has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Park, J. H., Park, J. H., Suk, S.-H., Koh, I.-S., Hwang, S.-H., Song, H.-K., Lee, J. H. Tags: Ischemic Stroke Diagnosis Source Type: research

Sumoylation of LYS590 of NCX3 f-Loop by SUMO1 Participates in Brain Neuroprotection Induced by Ischemic Preconditioning Basic Sciences
Conclusions— Finally, this study suggests that NCX3 sumoylation might be a new target to enhance ischemic preconditioning-induced neuroprotection.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Cuomo, O., Pignataro, G., Sirabella, R., Molinaro, P., Anzilotti, S., Scorziello, A., Sisalli, M. J., Di Renzo, G., Annunziato, L. Tags: Animal Models of Human Disease, Ion Channels/Membrane Transport, Ischemia Basic Sciences Source Type: research

Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus.
This study was to reveal the mechanisms by which baicalin protected hippocampal neurons and improved learning and memory impairment after global cerebral ischemia/reperfusion in gerbil. In the present study, the Morris water maze test showed that baicalin significantly improved learning and memory impairment after global cerebral ischemia/reperfusion in gerbils. Laser scanning confocal fluorescence microscope examination showed that baicalin suppressed OGD-induced augmentation of intracellular calcium concentration. Western blotting analysis indicated that baicalin suppressed ischemia-caused elevated phosphorylation level ...
Source: Brain Research - March 21, 2016 Category: Neurology Authors: Wang P, Cao Y, Yu J, Liu R, Bai B, Qi H, Zhang Q, Guo W, Zhu H, Qu L Tags: Brain Res Source Type: research

Nuclear translocation of histone deacetylase 4 induces neuronal death in stroke.
Abstract Mounting evidence suggests that epigenetic modifications play critical roles in the survival/death of stressed neurons. Chief among these modifications is the deacetylation of histones within the chromatin by histone deacetylases (HDACs). HDAC4 is highly expressed in neurons and is usually trapped in cytosol. However, tightly regulated signal-dependent shuttling of this molecule between cytosol and nucleus occurs. Here, we studied the intracellular trafficking of HDAC4 and regulatory mechanisms during stroke. HDAC4 translocated from the cytosol into the nucleus of neurons in response to stroke induced by ...
Source: Neurobiology of Disease - March 8, 2016 Category: Neurology Authors: Yuan H, Denton K, Liu L, Li XJ, Benashski S, McCullough L, Li J Tags: Neurobiol Dis Source Type: research

Ischemic stroke in a young patient with Fahr’s disease: a case report
Fahr’s disease is a rare neurodegenerative disorder characterized by diffuse intracranial calcium deposition and associated cell loss mainly in bilateral basal ganglia and dentate nuclei of the cerebellum. Sub...
Source: BMC Neurology - March 8, 2016 Category: Neurology Authors: Chih-Sheng Yang, Chung-Ping Lo and Man-Chun Wu Source Type: research

Serum Calcium and Phosphate Levels and Short- and Long-Term Outcomes in Acute Intracerebral Hemorrhage Patients
We investigated whether admission serum calcium and phosphate levels are associated with short- and long-term outcomes in patients with acute intracerebral hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2016 Category: Neurology Authors: Shoujiang You, Qiao Han, Jiaping Xu, Chongke Zhong, Yu Zhang, Huihui Liu, Yanlin Zhang, Xinshun Xu, Chunfeng Liu, Yongjun Cao Source Type: research

Guideline of neuropathic pain treatment and dilemma from neurological point of view.
Authors: Yang CM, Chen NC, Shen HC, Chou CH, Yeh PS, Lin HJ, Chang CY, Cheng TJ, Lin KC Abstract Neuropathic pain is a complicated symptomatic disease as migraine in recent years. Not because the pain character differed from the nociceptive inflammatory symptoms but because of its complexity of mechanisms. Though peripheral sensitization, ectopic discharge, central sensitization, central re-organization and loss of inhibition play part of roles in mechanisms, however, based on this mechanistic treatment, the outcome still disappointed physicians and patients, exampled as central post-stroke central pain (CPSP). The...
Source: Acta Neurologica Taiwanica - December 12, 2015 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Activation of the phosphatidylinositol 3‐kinase pathway plays important roles in reduction of cerebral infarction by cilnidipine
In this study, we investigated whether cilnidipine has therapeutic effects in an animal model of cerebral infarction. After determination of the most effective dose of cilnidipine, a total of 128 rats were subjected to middle cerebral artery occlusion. Neurobehavioral function test and brain MRI were performed, and rats with similar sized infarcts were randomized to either the cilnidipine group or the control group. Cilnidipine treatment was performed with reperfusion after 2‐h occlusion. Western blots and immunohistochemistry were also performed after 24‐h occlusion. Initial infarct volume on diffusion‐weighted MRI ...
Source: Journal of Neurochemistry - August 31, 2015 Category: Neurology Authors: Jeong‐Woo Son, Hojin Choi, Arum Yoo, Hyun‐Hee Park, Young‐Seo Kim, Kyu‐Yong Lee, Young Joo Lee, Seong‐Ho Koh Tags: Original Article Source Type: research

Cerebrovascular correlates of vitamin D deficiency in older adults living near the Equator: results from the Atahualpa Project
This study shows an association of vitamin D deficiency with diffuse subcortical brain damage in older adults living in a tropical region. Lack of awareness of the importance of vitamin D deficiency might be one of the factors influencing the high prevalence of white matter hyperintensities of presumed vascular origin in underserved Latin American populations.
Source: International Journal of Stroke - August 28, 2015 Category: Neurology Authors: Oscar H. Del Brutto, Robertino M. Mera, Jorge Macias, Gabriela Morales, Mauricio Zambrano Tags: Panorama Source Type: research

Intracranial Carotid Calcification on Cranial Computed Tomography: Visual Scoring Methods, Semiautomated Scores, and Volume Measurements in Patients With Stroke Clinical Sciences
Conclusions— Visual scores correlate highly with quantitative intracranial internal carotid artery calcification measures, with excellent observer agreements. Visual intracranial internal carotid artery scores could be a rapid and practical method for epidemiological studies.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Subedi, D., Zishan, U. S., Chappell, F., Gregoriades, M.-L., Sudlow, C., Sellar, R., Wardlaw, J. Tags: Cerebrovascular disease/stroke, CT and MRI, Carotid Stenosis, Risk Factors for Stroke Clinical Sciences Source Type: research

Suppression of spreading depolarization and stabilization of dendritic spines by GLYX-13, an NMDA receptor glycine-site functional partial agonist.
Abstract Cortical spreading depolarization (SD) is a slow self-propagating wave of mass cellular depolarization in brain tissue, thought to be the underlying cause of migraine scintillating scotoma and aura, and associated with stroke, traumatic brain injury, and termination of status epilepticus. The N-methyl-D-aspartate subtype of glutamate receptor (NMDAR), which gates influx of calcium and is an important trigger of long-term synaptic plasticity, is also a contributor to the initiation and propagation of SD. The current study tested the potential of pharmacological modulation of NMDAR activity through the obli...
Source: Experimental Neurology - August 2, 2015 Category: Neurology Authors: Zhang XL, Shuttleworth CW, Moskal JR, Stanton PK Tags: Exp Neurol Source Type: research

Intakes of magnesium, potassium, and calcium and the risk of stroke among men
ConclusionsA diet rich in magnesium, potassium, and calcium may contribute to reduced risk of stroke among men. Because of significant collinearity, the independent contribution of each cation is difficult to define.
Source: International Journal of Stroke - June 4, 2015 Category: Neurology Authors: Sally N. Adebamowo, Donna Spiegelman, Alan J. Flint, Walter C. Willett, Kathryn M. Rexrode Tags: Research Source Type: research

Evaluation of the Differences in the Effects of Antihypertensive Drugs on Blood Pressure Variability by 24-Hour Ambulatory Blood Pressure Monitoring in Chronic Cerebrovascular Disease
It has been suggested that antihypertensive drug therapy is attributable to the lower blood pressure variability, we investigated the effects of 4 classes of antihypertensives on the blood pressure variability; in addition, we also compared the effects among 4 calcium channel blockers.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2015 Category: Neurology Authors: Ryoji Nishioka, Shunsuke Kinoshita, Michio Shiibashi, Tomokazu Shimazu, Yoshihiko Nakazato, Toshimasa Yamamoto, Naotoshi Tamura, Nobuo Araki Source Type: research

The Possible Damaged Mechanism and the Preventive Effect of Monosialotetrahexosylganglioside in a Rat Model of Cerebral Ischemia-Reperfusion Injury
The pathogenesis of cerebral ischemia-reperfusion injury (CIRI) is not completely clear and therapies are limited now. Therefore, our study aimed to investigate the possible pathogenesis and preventive approach of CIRI through analyzing changes of aspartate (Asp), glutamate (Glu), mitochondrial calcium (MCa), calmodulin (CaM), and malondialdehyde (MDA) contents and ultramicropathology in hippocampus and cerebral cortex of ischemic susceptible injured regions and the effect of monosialotetrahexosylganglioside (GM1) in the rat model of CIRI.
Source: Journal of Stroke and Cerebrovascular Diseases - April 28, 2015 Category: Neurology Authors: Jie Zhang, Xin Fang, Yiyi Zhou, Xia Deng, Yi Lu, Jiao Li, Shujuan Li, Bo Wang, Renshi Xu Source Type: research

Lower Serum Calcium Level Is Associated With Hemorrhagic Transformation After Thrombolysis Brief Reports
Conclusions— Lower admission serum calcium level is independently associated with HT after IVT, and this hypothesis needs larger confirmatory trials.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Guo, Y., Yan, S., Zhang, S., Zhang, X., Chen, Q., Liu, K., Liebeskind, D. S., Lou, M. Tags: Thrombolysis Brief Reports Source Type: research