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Condition: Hypertension
Nutrition: Calcium

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Total 337 results found since Jan 2013.

Activation of the phosphatidylinositol 3‐kinase pathway plays important roles in reduction of cerebral infarction by cilnidipine
In this study, we investigated whether cilnidipine has therapeutic effects in an animal model of cerebral infarction. After determination of the most effective dose of cilnidipine, a total of 128 rats were subjected to middle cerebral artery occlusion. Neurobehavioral function test and brain MRI were performed, and rats with similar sized infarcts were randomized to either the cilnidipine group or the control group. Cilnidipine treatment was performed with reperfusion after 2‐h occlusion. Western blots and immunohistochemistry were also performed after 24‐h occlusion. Initial infarct volume on diffusion‐weighted MRI ...
Source: Journal of Neurochemistry - August 31, 2015 Category: Neurology Authors: Jeong‐Woo Son, Hojin Choi, Arum Yoo, Hyun‐Hee Park, Young‐Seo Kim, Kyu‐Yong Lee, Young Joo Lee, Seong‐Ho Koh Tags: Original Article Source Type: research

O60. Treatment of hypertension in pregnancy
Conclusions According to recent guidelines, in the absence of randomised clinical trials recommendations how hypertension should be treated in pregnant women, can only be guided by experts’ opinion based on case reports and their meta-analyses.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - August 31, 2015 Category: OBGYN Source Type: research

Valvular calcification upon initiating dialysis predict the appearance of cardiovascular events in patient evolution.
CONCLUSIONS: The prevalence of VC at the commencement of dialysis is very high and its presence is an independent predictor of event and cardiovascular mortality presentation in the course of follow-up. PMID: 26300509 [PubMed - as supplied by publisher]
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - August 25, 2015 Category: Urology & Nephrology Tags: Nefrologia Source Type: research

Bradycardia caused by Intravenous Nicardipine in an Elderly Patient with Acute Ischemic Infarct
We report the case of an elderly patient with an acute ischemic stroke who developed nicardipineinduced bradycardia in the ED.
Source: The American Journal of Emergency Medicine - August 17, 2015 Category: Emergency Medicine Authors: Michael E. Abboud, Sarah E. Frasure Tags: Case Report Source Type: research

Long-Term Anti-Hypertensive Therapy and Stroke Prevention: A Meta-Analysis
Conclusion Among the antihypertensive classes, CCBs were most effective in reducing the long-term incidence of stroke, whereas β-blockers were associated with significantly increased risk.
Source: American Journal of Cardiovascular Drugs - June 9, 2015 Category: Cardiology Source Type: research

Effects of blood pressure-lowering on outcome incidence in hypertension: 5. Head-to-head comparisons of various classes of antihypertensive drugs – overview and meta-analyses
Conclusions: The results of all available evidence from head-to-head drug class comparisons do not allow the formulation of a fixed paradigm of drug choice valuable for all hypertensive patients, but the differences found may suggest specific choices in specific conditions, or preferable combinations of drugs.
Source: Journal of Hypertension - June 5, 2015 Category: Cardiology Tags: Reviews Source Type: research

Intakes of magnesium, potassium, and calcium and the risk of stroke among men
ConclusionsA diet rich in magnesium, potassium, and calcium may contribute to reduced risk of stroke among men. Because of significant collinearity, the independent contribution of each cation is difficult to define.
Source: International Journal of Stroke - June 4, 2015 Category: Neurology Authors: Sally N. Adebamowo, Donna Spiegelman, Alan J. Flint, Walter C. Willett, Kathryn M. Rexrode Tags: Research Source Type: research

Normocalcaemic, vitamin D sufficient hyperparathyroidism ‐ high prevalence and low morbidity in the general population A long‐term follow‐up study, the WHO MONICA project, Gothenburg, Sweden
ConclusionsThis small random population study showed that nHPT was common, 11% at follow‐up. Only one individual developed mild hypercalcaemia in 13 years. Previous S‐PTH was predictive of nHPT and hypertension was prevalent, but no increase in hard end points was seen over a 17‐year period.This article is protected by copyright. All rights reserved.
Source: Clinical Endocrinology - May 18, 2015 Category: Endocrinology Authors: Georgios Kontogeorgos, Penelope Trimpou, Christine M. Laine, Göran Oleröd, Anders Lindahl, Kerstin Landin‐Wilhelmsen Tags: Rapid Communication Source Type: research

Massive Left Ventricular Calcification
94-year-old male presented for follow-up for shortness of breath. He has a history of two episodes of anterior and inferior myocardial infarction (MI) (eight and thirteen years ago) with stent revascularization, ischemic cardiomyopathy, implantable cardioverter defibrillator, paroxysmal atrial fibrillation, hypertension, hyperlipidemia, diabetes, and stroke. Lab investigation showed normal kidney function and calcium level. Echocardiography showed a reduced left ventricular (LV) ejection fraction of 25%, diastolic dysfunction, severe anteroseptal hypokinesis, otherwise normal LV.
Source: International Journal of Cardiology - April 28, 2015 Category: Cardiology Authors: Anas Alani Tags: Letter to the Editor Source Type: research

HYT-Hypertension in Turkey: A Cross-Sectional Survey on Blood Pressure Control with Calcium Channel Blockers Alone or Combined with Other Antihypertensive Drugs
Conclusions Taken together these findings provide evidence that dihydropyridine-type CCBs, particularly when combined with ACE-inhibitors or angiotensin II receptors blockers, allow to achieve a blood pressure control better than the one reported in the same geographic area by other treatment strategies based on different combinations of diuretics, beta-blockers, ACE-inhibitors, angiotensin II receptors blockers and calcium channel blockers.
Source: High Blood Pressure and Cardiovascular Prevention - April 22, 2015 Category: Cardiology Source Type: research

CT Angiogram Helps to Predict Ischemic Stroke in Dizzy Patients, but NOT Better than the Clinical Examination (P3.084)
Conclusions: In patients with subjective dizziness, stroke risk factors and focal exam findings predict acute ischemic stroke. Calcification on CTA is also predictive, but does not significantly improve sensitivity.Disclosure: Dr. Chen has nothing to disclose. Dr. Schneider has nothing to disclose. Dr. Marsh has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chen, K., Schneider, A., Marsh, E. Tags: Cerebrovascular Disease and Interventional Neurology: Hemorrhagic and Ischemic Stroke Source Type: research

Drug Therapy of Apparent Treatment-Resistant Hypertension: Focus on Mineralocorticoid Receptor Antagonists
Abstract Apparent treatment-resistant hypertension (aTRH) is defined as blood pressure (BP) >140/90 mmHg despite three different antihypertensive drugs including a diuretic. aTRH is associated with an increased risk of cardiovascular events, including stroke, chronic renal failure, myocardial infarction, congestive heart failure, aortic aneurysm, atrial fibrillation, and sudden death. Preliminary studies of renal nerve ablation as a therapy to control aTRH were encouraging. However, these results were not confirmed by the Symplicity 3 trial. Therefore, attention has refocused on drug therapy. Secondary forms o...
Source: Drugs - March 19, 2015 Category: Drugs & Pharmacology Source Type: research

Recommendations for the Treatment of Hypertension in Elderly People.
Authors: Rubio-Guerra AF, Duran-Salgado MB Abstract High blood pressure is a major cardiovascular risk factor. The prevalence of hypertension increases with aging. As a consequence of changes in arterial wall that leads to arterial stiffness, the majority of elderly patients suffer isolated systolic hypertension. The evidence strongly supports that hypertension in the elderly is associated with an increase in stroke risk and cardiovascular mortality and morbidity. Several trials have shown the benefits of treating hypertension in elderly patients. Even in the very old patients, the use of antihypertensive agents su...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - March 12, 2015 Category: Cardiology Tags: Cardiovasc Hematol Agents Med Chem Source Type: research

Volumetric analysis of central body fat accurately predicts incidence of diabetes and hypertension in adults
Conclusions Central body fat and BMI equally and highly predict incidence of hypertension and type 2 diabetes.
Source: BMC Obesity - February 25, 2015 Category: Eating Disorders and Weight Management Source Type: research

Antihypertensive Drugs, Prevention of Cognitive Decline and Dementia: A Systematic Review of Observational Studies, Randomized Controlled Trials and Meta-Analyses, with Discussion of Potential Mechanisms
Conclusion Antihypertensive drugs, particularly calcium channel blockers and renin–angiotensin system blockers, may be beneficial in preventing cognitive decline and dementia. However, further randomized controlled trials with longer periods of follow-up and cognition as the primary outcome are needed to confirm these findings.
Source: CNS Drugs - February 21, 2015 Category: Neurology Source Type: research