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Condition: Hypertension
Management: WHO

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Total 152 results found since Jan 2013.

Pharmacotherapy for hypertension in adults aged 18 to 59 years.
CONCLUSIONS: Antihypertensive drugs used to treat predominantly healthy adults aged 18 to 59 years with mild to moderate primary hypertension have a small absolute effect to reduce cardiovascular mortality and morbidity primarily due to reduction in cerebrovascular mortality and morbidity. All-cause mortality and coronary heart disease were not reduced. There is lack of good evidence on withdrawal due to adverse events. Future trials in this age group should be at least 10 years in duration and should compare different first-line drug classes and strategies. PMID: 28813123 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - August 16, 2017 Category: General Medicine Authors: Musini VM, Gueyffier F, Puil L, Salzwedel DM, Wright JM Tags: Cochrane Database Syst Rev Source Type: research

Blood pressure targets for hypertension in older adults.
CONCLUSIONS: At the present time there is insufficient evidence to know whether a higher BP target (less than150 to 160/95 to 105 mmHg) or a lower BP target (less than 140/90 mmHg) is better for older adults with high BP. Additional good-quality trials assessing BP targets in this population are needed. PMID: 28787537 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - August 8, 2017 Category: General Medicine Authors: Garrison SR, Kolber MR, Korownyk CS, McCracken RK, Heran BS, Allan GM Tags: Cochrane Database Syst Rev Source Type: research

Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India
Conclusion: Greenness, ISA, and NTL were associated with increased SBP, DBP, and cPP, and with reduced FMD, suggesting a possible additional EVA pathway for the relationship between urbanization and increased CVD prevalence in urban India. https://doi.org/10.1289/EHP541 Received: 20 May 2016 Revised: 03 January 2017 Accepted: 23 January 2017 Published: 02 August 2017 Address correspondence to K.J. Lane, Yale School of Forestry and Environmental Studies, 195 Prospect Street, New Haven, CT 06511 USA. Telephone: (781) 696-4537; Email: kevin.lane@yale.edu Supplemental Material is available online (https://doi.org/10.1289...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence
Conclusions: Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577 Received: 01 June 2016 Revised: 26 February 2017 Acce...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Research on the Cause of Death for Severe Stroke Patients
ConclusionsThe most common cause of death in stroke patients was damage to the central nervous system. Independent risk factors were brain herniation, multiple organ failure, dyslipidemia, community‐acquired lung infection, the use of mechanical ventilation, hypoproteinemia, a history of hypertension, and hospital‐acquired pneumonia. Clinicians should be aware of the presence and possible effects of these conditions. Early prevention, monitoring and intervention to modify controllable risk factors will improve patient prognosis. Relevance to clinical practiceClinicians should be aware of the multiple independent risk f...
Source: Journal of Clinical Nursing - July 5, 2017 Category: Nursing Authors: Mei ‐zhen Yuan, Feng Li, Qin Fang, Wei Wang, Jing‐jing Peng, De‐yu Qin, Xue‐feng Wang, Guang‐wei Liu Tags: Original Article Source Type: research

Another Side of a Low-Salt Diet: Reductions in the Salinity of Drinking Water May Lower Blood Pressure
PDF Version (365 KB) About This Article Published: 23 June 2017 Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If you need assistance accessing journal content, please contact ehponline@niehs.nih.gov. Our staff will work with you to assess and meet your accessibility needs within 3 working days. Related EHP Article Drinking Water Salinity and Raised Blood Pressure: Evidence f...
Source: EHP Research - June 23, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Science Selections Source Type: research

Ambient Temperature and Stillbirth: A Multi-Center Retrospective Cohort Study
Conclusions: Extremes of local ambient temperature may have chronic and acute effects on stillbirth risk, even in temperate zones. Temperature-related effects on pregnancy outcomes merit additional investigation. https://doi.org/10.1289/EHP945 Received: 09 August 2016 Revised: 06 December 2016 Accepted: 22 December 2016 Published: 22 June 2017 Address correspondence to P. Mendola, Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6710B Rockledge Dr., Room 3119, Bethesda, MD, 20817, USA. Telephone: (301) 496-526...
Source: EHP Research - June 22, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Burden of disease from road traffic and railway noise – a quantification of healthy life years lost in Sweden
Conclusions Road traffic and railway noise contribute significantly to the burden of disease in Sweden each year. The total numbe r of DALY should, however, be interpreted with caution due to limitations in data quality.byEriksson C, Bodin T, Selander J. doi:10.5271/sjweh.3651
Source: Scandinavian Journal of Work, Environment and Health - June 9, 2017 Category: Occupational Health Tags: Original article Source Type: research

Burden of disease from road traffic and railway noise - a quantification of healthy life years lost in Sweden.
Conclusions Road traffic and railway noise contribute significantly to the burden of disease in Sweden each year. The total number of DALY should, however, be interpreted with caution due to limitations in data quality. PMID: 28599022 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Work, Environment and Health - June 9, 2017 Category: Occupational Health Authors: Eriksson C, Bodin T, Selander J Tags: Scand J Work Environ Health Source Type: research

Invasive Hemodynamics of Pulmonary Disease and the Right Ventricle
Publication date: July 2017 Source:Interventional Cardiology Clinics, Volume 6, Issue 3 Author(s): David Silber, Justine LachmannTeaser Pulmonary hypertension (PH) falls into 5 groups, as defined by the World Health Organization. Swan-Ganz catheters determine precapillary versus postcapillary PH. The hemodynamic values of PH at rest and with vasodilatory challenge categorize the etiology of PH and guide treatment. RV maladaptations to increased pulmonary vascular resistance (PVR) and the chronicity of the right ventricle's (RV) response to increased PH and/or increased PVR can be understood with pressure-volume (PV) loops...
Source: Interventional Cardiology Clinics - June 7, 2017 Category: Cardiology Source Type: research

Drinking Water Salinity and Raised Blood Pressure: Evidence from a Cohort Study in Coastal Bangladesh
Conclusions: DWS is an important source of daily sodium intake in salinity-affected areas and is a risk factor for hypertension. Considering the likely increasing trend in coastal salinity, prompt action is required. Because MAR showed variable effects, alternative technologies for providing reliable, safe, low-sodium fresh water should be developed alongside improvements in MAR and evaluated in “real-life” salinity-affected settings. https://doi.org/10.1289/EHP659 Received: 01 February 2016 Revised: 14 June 2016 Accepted: 31 August 2016 Published: 30 May 2017 Address correspondence to Dr. Pauline Scheelbeek, ...
Source: EHP Research - May 30, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research

The effect of statins on National Institutes of Health Stroke Scale (NiHSS) in Ischemic stroke.
Conclusion. According to the findings of this research, taking statins before the onset of stroke and immediately after it showed no significant difference in the level of following dysfunction, measured with NIHSS, and further studies are necessary. PMID: 28316706 [PubMed]
Source: Journal of Medicine and Life - March 23, 2017 Category: Journals (General) Tags: J Med Life Source Type: research

Combination Pills for Treatment of High Blood Pressure: Cost-effectiveness in The Asia Pacific Region
High blood pressure (BP) is the leading cause of preventable disease and death globally[1]. Treatment of high BP substantially reduces major cardiovascular events, a 10mmHg reduction in systolic BP (SBP) reduces the relative risk of coronary events by 22% and stroke by 41%[2]. The World Health Organization estimates the global prevalence of high BP is 22% in adults, and prevalence is highest in low and middle income countries[3]. Much of the global burden of high BP occurs in the Asia Pacific region, where almost 60% of the world's population reside;[4] and, where affordability of treatment is vital to implementation.
Source: Heart, Lung and Circulation - February 25, 2017 Category: Cardiology Authors: Emily R Atkins, Thomas Lung, Julie Redfern Tags: EDITORIAL Source Type: research

Long-term daily drinking linked to stiffening of the arteries in men
Conclusion This prospective cohort study aimed to look at the relationship between long-term alcohol patterns and stiffness of the arteries as a potential indicator of cardiovascular health. The researchers found men who were stable heavy drinkers had stiffer arteries compared with stable moderate drinkers. Male former drinkers also had increasingly stiffer arteries over the following four to five years compared with consistent moderate drinkers. There were no significant findings seen for women at all. But this study does have limitations: This type of study is not able to prove drinking causes stiffness of the arter...
Source: NHS News Feed - February 21, 2017 Category: Consumer Health News Tags: Heart/lungs Food/diet Source Type: news

Making Sense of Nutraceuticals in China
The Chinese nutraceutical market is considered the third largest in the world after the US and Japan, or the fourth largest if Europe is counted as a single market.Despite strong fundamentals and high rates of annual growth, though, the Chinese market remains some way from realizing its true potential. Its evolution is muddied by ambiguities around what nutraceuticals actually are and how they should be managed.The result has been polarization between over-zealous regulation of so-called health foods, and a grey market where products have skirted approval procedures through questionable positioning or by exploiting alterna...
Source: EyeForPharma - February 10, 2017 Category: Pharmaceuticals Authors: Marc Yates Source Type: news