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Condition: Hypertension
Management: WHO
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Total 152 results found since Jan 2013.
Effects of sotatercept on haemodynamics and right heart function: analysis of the STELLAR trial
Conclusion
In pre-treated patients with PAH, sotatercept demonstrated substantial improvements in PA pressures, PA compliance, PA–RV coupling and right heart function.
Source: European Respiratory Journal - September 21, 2023 Category: Respiratory Medicine Authors: Souza, R., Badesch, D. B., Ghofrani, H. A., Gibbs, J. S. R., Gomberg-Maitland, M., McLaughlin, V. V., Preston, I. R., Waxman, A. B., Grünig, E., Kopec, G., Meyer, G., Olsson, K. M., Rosenkranz, S., Lin, J., Johnson-Levonas, A. O., de Oliveira Pena Tags: Original Articles: Pulmonary vascular disease Source Type: research
Effects of sotatercept on haemodynamics and right heart function: analysis of STELLAR trial
CONCLUSION: In pre-treated patients with PAH, sotatercept demonstrated substantial improvements in PA pressures, PA compliance, PA-RV coupling and right heart function.PMID:37696565 | DOI:10.1183/13993003.01107-2023
Source: Respiratory Care - September 11, 2023 Category: Respiratory Medicine Authors: Rogerio Souza David B Badesch H Ardeschir Ghofrani J Simon R Gibbs Mardi Gomberg-Maitland Vallerie V McLaughlin Ioana R Preston Aaron B Waxman Ekkehard Gr ünig Grzegorz Kope ć Gisela Meyer Karen M Olsson Stephan Rosenkranz Jianxin Lin Amy O Johnson-Levo Source Type: research
Use of hospital services by patients with chronic conditions in sub-Saharan Africa: a systematic review and meta-analysis
CONCLUSION: Among patients seeking hospital care in sub-Saharan Africa, multimorbidity remains poorly described despite high burdens of individual chronic diseases. Prospective public health studies of multimorbidity burden are needed to generate integrated and context-specific health system interventions that act to maximize patient survival and well-being.PMID:37638357 | PMC:PMC10452942 | DOI:10.2471/BLT.22.289597
Source: Bulletin of the World Health Organization - August 28, 2023 Category: International Medicine & Public Health Authors: Stephen A Spencer Jamie Rylance Jennifer K Quint Stephen B Gordon Paul Dark Ben Morton Source Type: research
Roche enters partnership with Alnylam to co-develop and co-commercialise RNAi therapeutic zilebesiran to treat hypertension in patients with high cardiovascular risk
Partnership combines Roche ’s proven track record of successfully developing and launching innovative medicines worldwide withAlnylam ’s leadership in RNAi therapeuticsZilebesiran, a Phase 2 RNAi therapeutic, has best-in-disease potential for patients with hypertension at high risk of cardiovascular morbidity and mortality, by robustly and durably lowering blood pressureHypertension, the leading cause of cardiovascular disease, affects more than 1.2 billion adults worldwide. While several therapies exist, a significant unmet need, especially for high risk patients, remains.1Basel, 24 July 2023 - Roche (SIX: RO, ROG; OT...
Source: Roche Media News - July 24, 2023 Category: Pharmaceuticals Source Type: news
Incident risk and burden of cardiovascular diseases attributable to long-term NO < sub > 2 < /sub > exposure in Chinese adults
CONCLUSIONS: This study provided nationwide cohort evidence for elevated risks of CVD incidence associated with long-term ambient NO2 exposure among Chinese adults, particularly in urban areas and among overweight/obese individuals. Our findings highlighted that reducing NO2 exposure below 2021 WHO guideline could help prevent a substantial portion of incident CVD cases in China.PMID:37478679 | DOI:10.1016/j.envint.2023.108060
Source: Environment International - July 21, 2023 Category: Environmental Health Authors: Kai Wang Yang Yuan Qun Wang Zhiming Yang Yu Zhan Yaqi Wang Fang Wang Yunquan Zhang Source Type: research
Ventricular global function index is associated with clinical outcomes in pediatric pulmonary hypertension
CONCLUSIONS: RV GFI was associated with CAO in this cohort, and inclusion in multivariable models had increased predictive value compared to RVEF. GFI uses readily available CMR data without additional post-processing and may provide additional prognostic value in pediatric PH patients beyond traditional CMR markers.PMID:37400886 | PMC:PMC10316558 | DOI:10.1186/s12968-023-00947-8
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: Hieu T Ta Paul J Critser Michal Sch äfer Nicholas J Ollberding Michael D Taylor Michael V Di Maria Russel Hirsch D Dunbar Ivy Benjamin S Frank Source Type: research
New Urban Health ‘Accelerator’ Aims to Transform Cardiovascular Population Health Globally
ihadmin2May 22, 2023May 22, 2023GenevaThe CARDIO4Cities Accelerator by Novartis Foundation and IntraHealth International aims to replicate the successful CARDIO4Cities approach in 30 major cities within three years to transform cardiovascular population health and equity globally.Results of initial programs in S ão Paulo, Dakar and Ulaanbaatar show the cost-effective approach averted up to 13% of strokes and 12% of heart attacks during implementation.Experts say public-private partnerships are key to address the growing burden of cardiovascular disease, the world ’s leading cause of death,according to the World Health O...
Source: IntraHealth International - May 22, 2023 Category: International Medicine & Public Health Authors: ihadmin2 Source Type: news
