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Condition: Atrial Fibrillation
Management: Hospitals

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Total 621 results found since Jan 2013.

The CHADS2 Components Are Associated with Stroke-Related In-hospital Mortality in Patients with Atrial Fibrillation
The CHADS2 score predicts stroke risk in patients with atrial fibrillation. Although strokes caused by atrial fibrillation carry the highest mortality when compared with other etiologies, it is not known whether the CHADS2 score predicts stroke-related mortality in patients with atrial fibrillation. We hypothesized that higher CHADS2 scores would be associated with higher stroke-related in-hospital mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - July 28, 2015 Category: Neurology Authors: Shadi Yaghi, Ayesha Sherzai, Markeith Pilot, Dean Sherzai, Mitchell S.V. Elkind Source Type: research

Differential Proteomics for Distinguishing Ischemic Stroke from Controls: a Pilot Study of the SpecTRA Project
AbstractA diagnostic blood test for stroke is desirable but will likely require multiple proteins rather than a single “troponin.” Validating large protein panels requires large patient numbers. Mass spectrometry (MS) is a cost-effective tool for this task. We compared differences in the abundance of 147 protein markers to distinguish 20 acute cerebrovascular syndrome (ACVS) patients who presented to the Emergen cy Department of one urban hospital within<  24 h from onset) and from 20 control patients who were enrolled via an outpatient neurology clinic. We targeted proteins from the stroke literature plus cardio...
Source: Translational Stroke Research - January 24, 2018 Category: Neurology Source Type: research

Impact of Arrhythmia in Hospital Mortality in Acute Ischemic Stroke Patients: A Retrospective Cohort Study in Northern Mexico
Stroke remains one of the leading causes of death globally. 1 In Mexico, it represents the 6th cause of death2 and contributes with 688.19 DALYs per 100,000 people,3 constituting a major cause of burden of disease in the country. Heart rhythm dysfunctions following acute ischemic strokes (AIS) have been previously reported,4 –9 and it is expected that 25-30% of patients will be diagnosed with any type of arrhythmia after stroke.6,9 Kallmünze et al. reported the incidence of several post-stroke arrhythmias, such as atrial fibrillation (AF), focal atrial tachycardia, undetermined supraventricular tachycardia, ventricu la...
Source: Journal of Stroke and Cerebrovascular Diseases - December 16, 2021 Category: Neurology Authors: J. De la Fuente-Mart ínez, A. Infante-Valenzuela, D. Martínez-Roque, M. Cruz-Moreno, F. Góngora-Rivera Source Type: research

Predictors of In-hospital Mortality and the Risk of Symptomatic Intracerebral Hemorrhage after Thrombolytic Therapy with Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke
This study aimed to determine the independent predictors of in-hospital mortality (IHM) and the risk of sICH after rt-PA therapy. A total of 1007 patients (mean age, 72 ± 12 years; 52% women; mean National Institutes of Health Stroke Scale [NIHSS] score, 11.6 ± 5.6) with AIS treated with rt-PA were enrolled in this study during a 42-month period beginning in November 2007. Univariate and multivariate regression analyses were performed to estimate the predictors of IHM. Eighty-three of the 1007 patients (8.2%) died during hospitalization (mean duration of hospitalization, 10 ± 1.8 days). Logistic regression estimated the...
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2012 Category: Neurology Authors: Mohamed Al-Khaled, Christine Matthis, Jürgen Eggers Tags: Original Articles Source Type: research

Atrial Fibrillation and Stroke: It's About Point of View
In this issue of the journal, Frandsen et al report that the proportion of atrial fibrillation (AF)-associated ischemic strokes has not changed over 15 years (1997-2012) among all ischemic strokes in patients admitted to a Danish hospital.1 The finding may seem surprising because of the proven efficacy of oral anticoagulants for stroke prevention in patients with AF and the substantial world-wide diffusion effort during this interval. Indeed, the authors also found that the rate of prestroke use of oral anticoagulants (ie, in “treatment failures” in their stroke database) rose over the years in their patients suggest...
Source: Journal of Stroke and Cerebrovascular Diseases - April 30, 2015 Category: Neurology Authors: David C. Anderson, Richard W. Asinger Tags: Editorial Source Type: research

Detection of Atrial Fibrillation with Intermittent Handheld Electrocardiogram in Patients with Ischemic Stroke and Transient Ischemic Attack
This study aimed to explore the detection rate of atrial fibrillation in stroke and transient ischemic attack patients with intermittent handheld ECG in the clinical setting of Halland Hospital Halmstad.
Source: Journal of Stroke and Cerebrovascular Diseases - July 31, 2016 Category: Neurology Authors: Ann-Sofie Olsson, Johan Engdahl Source Type: research

Ischemic Stroke Risk After Acute Coronary Syndrome Stroke
BackgroundPrior studies show an increased risk of ischemic stroke (IS) after myocardial infarction; however, there is limited evidence on long‐term risk and whether it is directly related to cardiac injury. We hypothesized that the risk of IS after acute coronary syndrome is significantly higher if there is evidence of cardiac injury, such as ST‐segment elevation myocardial infarction (STEMI) or non‐STEMI, than when there is no evidence of cardiac injury, such as in unstable angina.Methods and ResultsAdministrative claims data were obtained from all emergency department encounters and hospitalizations at California's...
Source: JAHA:Journal of the American Heart Association - July 12, 2016 Category: Cardiology Authors: Yaghi, S., Pilot, M., Song, C., Blum, C. A., Yakhkind, A., Silver, B., Furie, K. L., Elkind, M. S. V., Sherzai, D., Sherzai, A. Z. Tags: Cerebrovascular Disease/Stroke, Acute Coronary Syndromes Original Research Source Type: research

Adenosine Diphosphate–Induced Platelet Aggregation Might Contribute to Poor Outcomes in Atrial Fibrillation–Related Ischemic Stroke
Systemic atherosclerosis is involved in ischemic damages and cardioembolism after atrial fibrillation (AF)–related ischemic stroke (IS). Platelet activation is a critical factor in systemic atherosclerosis; however, there is little information regarding the role of platelet activation on the outcome of AF-related IS. We investigated the relationship between adenosine diphosphate (ADP)–induced platelet aggregation and the long-term outcomes of AF-related IS. We studied 249 patients who were exclusively treated with anticoagulation therapy after they had experienced AF-related IS. We evaluated their platelet function 5 ...
Source: Journal of Stroke and Cerebrovascular Diseases - November 25, 2013 Category: Neurology Authors: Jae-Hyung Choi, Jae-Kwan Cha, Jae-Taeck Huh Tags: Original Articles Source Type: research

Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events
Apart from atrial fibrillation, indications for oral anticoagulation common in our clinical practice include rheumatic heart disease and mechanical heart valve replacement. Evaluation of current patient knowledge regarding oral anticoagulation therapy (OAT) is the first step in improving the quality of anticoagulation therapy and patient care. The aim of the present study was to assess the knowledge regarding OAT among patients with stroke and those at high risk of thromboembolic events in a tertiary care hospital in India.
Source: Journal of Stroke and Cerebrovascular Diseases - January 7, 2015 Category: Neurology Authors: Annu Alphonsa, Kamlesh K. Sharma, Gautam Sharma, Rohit Bhatia Source Type: research

High-Resolution Pulse Oximetry (HRPO): A Cost-Effective Tool in Screening for Obstructive Sleep Apnea (OSA) in Acute Stroke and Predicting Outcome
Obstructive sleep apnea (OSA) is a well-known risk factor for stroke. This is attributed to multiple mechanisms such as endothelial dysfunction, atrial fibrillation, hypertension, and comorbid obesity. STOP questionnaire alone is unreliable to diagnose OSA and in-hospital sleep study is costly and can be technically challenging. We used high-resolution pulse oximetry (HRPO) to test the feasibility of screening for OSA and predicting outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - August 7, 2018 Category: Neurology Authors: Sridhara Sastry Yaddanapudi, Maria Carissa Pineda, David W. Boorman, Richard E. Bryne, Krista Lim Hing, Sunil Sharma Source Type: research

Reduced Doses of Direct Oral Anticoagulants in Ischemic Stroke Patients with Nonvalvular Atrial Fibrillation
Background: The choice of standard or reduced doses of direct oral anticoagulants (DOACs) depends on patients ’ age, body weight, and renal function based on package instructions. Our aim was to conduct a simulation of DOAC dose using patients’ data obtained on admission. Methods: This retrospective study included 314 ischemic stroke patients with nonvalvular atrial fibrillation admitted to our hospital between September 2014 and February 2018. Data on age, body weight, creatinine, and creatinine clearance were collected for each subject, and simulation was conducted for the dose of each DOAC.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2018 Category: Neurology Authors: Ichiro Deguchi, Masaki Takao Source Type: research

Stroke Down to Fifth-Leading Killer in U.S. -- Here's What the Statistical Change Really Means
In the 1970s, Joseph Broderick was a resident at the Mayo Clinic in need of a focus for his fellowship. He decided to give stroke research a try. Part of the lure was all the unanswered questions, like: Who is most likely to have a stroke? Why do they have it when others seemingly like them don't? Is stroke getting more or less common? What can be done to prevent it? Another part of the lure was a landmark study on the frequency of stroke being done in the hospital's hometown of Rochester, Minnesota. Being part of it meant working for one of the nation's leading stroke researchers at the time, Jack Whisnant. By the mid-...
Source: Healthy Living - The Huffington Post - January 12, 2015 Category: Consumer Health News Source Type: news

Hospitals in GWTG-Stroke program more likely to provide recommended stroke treatment
Timely stroke treatment is critical to ensuring good outcomes for patients. A new national study compared two programs designed to help hospitals adhere to nationally accepted standards and guideline recommendations for stroke treatment and found that hospitals participating in the Get With The Guidelines–Stroke program were more likely than Primary Stroke Center–certified hospitals to provide all the guideline-based measures of care for patients.   The study appears in the Oct. 14 issue of the Journal of the American Heart Association.   The American Heart Association/American Stroke Association's ...
Source: UCLA Newsroom: Health Sciences - October 15, 2013 Category: Universities & Medical Training Source Type: news

Cardiac Imaging Within Emergency CT Angiography for Acute Stroke Can Detect Atrial Clots
This study was approved by the ethics committee of the medical faculty of the Ruhr University Bochum. FIGURE 1 Figure 1. Flow chart showing the selection of the study population. Results A total of 59 patients underwent emergency CCTA (Figure 2A) for suspected stroke, of which 44 received the final diagnosis ischemic stroke. There were 17 patients who had ischemic stroke or TIA and known or newly diagnosed atrial fibrillation (Table 1; mean age: 77.5 years, standard deviation: 8.4 years; 53% female). As hypothesized, intracardiac thrombi could be visualized: once in an artificially occluded left atrial appe...
Source: Frontiers in Neurology - April 9, 2019 Category: Neurology Source Type: research

Quality Improvement in Acute Ischemic Stroke Care in Taiwan: The Breakthrough Collaborative in Stroke
by Fang-I Hsieh, Jiann-Shing Jeng, Chang-Ming Chern, Tsong-Hai Lee, Sung-Chun Tang, Li-Kai Tsai, Hsun-Hsiang Liao, Hang Chang, Kenneth A. LaBresh, Hung-Jung Lin, Hung-Yi Chiou, Hou-Chang Chiu, Li-Ming Lien, for the BTS-Stroke Investigators In the management of acute ischemic stroke, guideline adherence is often suboptimal, particularly for intravenous thrombolysis or anticoagulation for atrial fibrillation. We sought to improve stroke care quality via a collaborative model, the Breakthrough Series (BTS)-Stroke activity, in a nationw ide, multi-center activity in Taiwan. A BTS Collaborative, a short-term learning system fo...
Source: PLoS One - August 2, 2016 Category: Biomedical Science Authors: Fang-I Hsieh Source Type: research