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Condition: Atrial Fibrillation
Management: Hospitals

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Total 621 results found since Jan 2013.

HRS 2016 roundup: Leadless pacers at the fore
Medtronic (NYSE:MDT) and St. Jude Medical (NYSE:STJ), aiming to distinguish their respective leadless pacemaker offerings, presented new data last week in San Francisco at the Heart Rhythm Society’s annual meeting. St. Jude said a subset of data from the Leadless II trial showed that its Nanostim device was was successfully retrieved in 14 patients up to 3.2 years after implantation, with no serious adverse events. “We’ve now shown that for patients requiring device upgrades or new leadless pacing options, late retrievability – even up to 3 years – is possible with the Nanostim leadless pacemak...
Source: Mass Device - May 9, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiovascular Clinical Trials Boston Scientific Cardiac Rhythm Management HRS 2016 Medtronic St. Jude Medical Source Type: news

Managing reversal of direct oral anticoagulants in emergency situations. Anticoagulation Education Task Force White Paper.
This report is based on findings from the Anticoagulation Education Task Force, which brought together patient groups and professionals representing different medical specialties with an interest in patient safety and expertise in AF, VTE, stroke, anticoagulation, and reversal agents, to discuss the current status of anticoagulation reversal and fundamental changes in management of bleeding associated with DOACs occasioned by the approval of idarucizumab, a specific reversal agent for dabigatran, as well as recent clinical data on specific reversal agents for factor Xa inhibitors. Recommendations are given for when there i...
Source: Thrombosis and Haemostasis - August 3, 2016 Category: Hematology Authors: Ageno W, Büller HR, Falanga A, Hacke W, Hendriks J, Lobban T, Merino J, Milojevic IS, Moya F, van der Worp HB, Randall G, Tsioufis K, Verhamme P, Camm AJ Tags: Thromb Haemost Source Type: research

Limb ischemia, an alarm signal to a thromboembolic cascade - renal infarction and nephrectomy followed by surgical suppression of the left atrial appendage.
We present the case of a 55-year-old male with mild hypertension and brief episodes of paroxysmal self-limiting atrial fibrillation (AF) since 2010. Despite a small cardioembolic risk score, CHA2DS2-Vasc=1 (Congestive heart failure, Hypertension, Age=75, Diabetes melitus, prior Stroke), the patient is effectively anticoagulated using acenocumarol. In December 2014, he showed signs of plantar transitory ischemia, for which he did not address the doctor. In early January 2015, he urgently presented at the hospital with left renal pain, caused by a renal infarction, diagnosed by computed tomography (CT) angiography. Left neph...
Source: Romanian Journal of Morphology and Embryology - August 17, 2016 Category: Journals (General) Tags: Rom J Morphol Embryol Source Type: research

Comparative effectiveness and safety of oral anticoagulants for atrial fibrillation in real-world practice: a population-based cohort study protocol
Introduction Anticoagulants are arguably the most important drug family of all, based on the frequency and duration of their use, and the clinical importance and frequency of benefits and harms. Several direct acting oral anticoagulants (DOACs) have recently joined warfarin for the treatment of atrial fibrillation, with a resultant significant expansion in use of oral anticoagulants (OACs). Our objectives are to compare safety and effectiveness of DOACs versus warfarin in a full population where anticoagulation management is good and to identify which types of patients do better with DOACs versus warfarin and vice versa. ...
Source: BMJ Open - November 23, 2016 Category: Journals (General) Authors: Holbrook, A., Dormuth, C., Morrow, R., Lee, A., Troyan, S., Li, G., Pullenyegum, E. Tags: Open access, Cardiovascular medicine, Pharmacology and therapeutics Protocol Source Type: research

Anticoagulation therapy in elderly patients with atrial fibrillation: results from the Registry of Atrial Fibrillation To Investigate the Implementation of New Guidelines (RAFTING)
Background: Patients with atrial fibrillation aged 75 years or older have a CHA2DS2VASc score that dictates oral anticoagulants. We recorded physicians’ anticoagulation attitudes in elderly patients with atrial fibrillation and assessed the impact of stroke and bleeding risk. Methods: Atrial Fibrillation To Investigate the Implementation of New Guidelines , a countrywide prospective registry performed in Greece during 2010, a period when only vitamin-K antagonists (VKA) were available, enrolled 1127 patients with atrial fibrillation diagnosis during Emergency Departments visit in 31 representative hospitals; 807 patient...
Source: Journal of Cardiovascular Medicine - May 18, 2017 Category: Cardiology Tags: Research articles Source Type: research

In patients with intracerebral haemorrhage and concomitant atrial fibrillation, optimal timing of reinitiating anticoagulants may be 7-8 weeks after ICH
Commentary on: Pennlert J, et al. Optimal timing of anticoagulant treatment after intracerebral haemorrhage in patients with atrial fibrillation. Stroke 2017:48;314–320. Context In patients with intracerebral haemorrhage (ICH) and a concomitant diagnosis of atrial fibrillation (AF), the clinical dilemma arises whether anticoagulant treatment should be (re)started and when.1 In the absence of results from randomised controlled trials, guidelines provide no firm recommendations. Several observational studies have suggested that reintroduction of oral anticoagulants may be associated with a reduction in thrombotic ...
Source: Evidence-Based Medicine - June 9, 2017 Category: Internal Medicine Authors: Klijn, C. J., Schreuder, F. H. Tags: Therapeutics/Prevention Source Type: research

Inappropriate left ventricular hypertrophy as a tool for risk stratification in patients with essential hypertension
Publication date: Available online 1 August 2017 Source:Cor et Vasa Author(s): Sergiy Lozinsky The alternative method of appropriate left ventricular mass prediction in subjects with normal BP and arterial hypertension was proposed. Also the associations of new indicator of LVM inappropriateness with myocardial infarction, stroke and persistent atrial fibrillation were studied. The study consisted of 2 stages. On the first stage 630 untreated hypertensive patients and 206 normotensive persons were studied using methods of office blood pressure (OBP) measurement, echocardiography (ECG), ambulatory blood pressure monitoring...
Source: Cor et Vasa - August 2, 2017 Category: Cardiology Source Type: research

Seminar The future of atrial fibrillation management: integrated care and stratified therapy
Atrial fibrillation is one of the major cardiovascular health problems: it is a common, chronic condition, affecting 2 –3% of the population in Europe and the USA and requiring 1–3% of health-care expenditure as a result of stroke, sudden death, heart failure, unplanned hospital admissions, and other complications. Early diagnosis of atrial fibrillation, ideally before the first complication occurs, remains a ch allenge, as shown by patients who are only diagnosed with the condition when admitted to hospital for acute cardiac decompensation or stroke.
Source: LANCET - April 28, 2017 Category: General Medicine Authors: Paulus Kirchhof Tags: Seminar Source Type: research

Mild troponin elevation in patients admitted to the emergency department with atrial fibrillation: 30-day post-discharge prognostic significance
AbstractPatients with atrial fibrillation (AF) often undergo troponin (Tn) testing in the emergency department (ED), but the clinical significance of mildly elevated values remains unclear. We evaluated short-term 30-day post-discharge outcomes in AF patients according to troponin levels. Out of 2181 AF patients evaluated in the ED (June 2014 to June 2015), we included consecutive admitted patients. Patients were grouped into those with normal Tn values ( ≤ 0.05 ng/mL), mild elevations (>  0.05–0.5 ng/mL, 10× URL) and marked elevations (>  0.5 ng/mL). Outcomes included acute coronary syndrome (ACS), revasc...
Source: Internal and Emergency Medicine - December 23, 2017 Category: Emergency Medicine Source Type: research

Abstract 175: Atrial Fibrillation in the USF Resident Clinics: Quality-Driven Medical Therapy Session Title: Poster Session AM
Patients with atrial fibrillation (afib) have a high rate of serious complications including stroke and decompensated heart failure. While patients with afib are five times more likely to suffer a stroke in their lifetime than the general population, this risk can be reduced by 64% with appropriate anticoagulation using warfarin or approved novel oral anticoagulants (NOACs). Reducing the morbidity and mortality from excess strokes is a common interest nationwide due to unsustainable healthcare costs, increasing human resource gaps in medicine, and payment reforms that hold physicians and healthcare organizations financiall...
Source: Circulation: Cardiovascular Quality and Outcomes - April 5, 2018 Category: Cardiology Authors: Sadic, E. Tags: Session Title: Poster Session AM Source Type: research

Inappropriate left ventricular hypertrophy as a tool for risk stratification in patients with essential hypertension
Publication date: April 2018Source: Cor et Vasa, Volume 60, Issue 2Author(s): Sergiy LozinskyAbstractThe alternative method of appropriate left ventricular mass prediction in subjects with normal BP and arterial hypertension was proposed. Also the associations of new indicator of LVM inappropriateness with myocardial infarction, stroke and persistent atrial fibrillation were studied.The study consisted of 2 stages. On the first stage 630 untreated hypertensive patients and 206 normotensive persons were studied using methods of office blood pressure (OBP) measurement, echocardiography (ECG), ambulatory blood pressure monito...
Source: Cor et Vasa - July 5, 2018 Category: Cardiology Source Type: research

ARENA-Project atrial fibrillation in the Rhein-Neckar region.
Authors: Baumann S, Grau A, Senges J, Schneider S, Alonso A, Katus HA, Thomas D, Waldecker B, Haass M, Zahn R, Zeymer U, Akin I, Kruska M, Fischer C, Borggrefe M Abstract Atrial fibrillation (AF) is the most common form of cardiac tachyarrhythmia. It is estimated that in the Rhein-Neckar region approximately 40,000-50,000 out of 2 million people are affected. Due to demographic changes in the near future there will be a significant increase in the prevalence of AF within the next decades. The ARENA project was initiated by the Foundation Institute for Cardiac Infarction Research (IHF) Ludwigshafen in cooperat...
Source: Herz - January 17, 2019 Category: Cardiology Tags: Herz Source Type: research

Leukoaraiosis is an independent predictor of intracranial hemorrhage in patients with atrial fibrillation
AbstractWe evaluated the predictive value of several clinical, radiological and laboratory parameters on the risk of predict intracranial hemorrhage (ICH) in patients with atrial fibrillation (AF). We conducted a case-control study on a consecutive hospital based series of patients with AF and ICH. A random sample of subjects with AF without ischemic or hemorrhagic stroke was selected from the same hospital in the same period to perform as the control group, with a ratio of two controls per case. All patients underwent the same evaluation protocol. Patients without neuroimaging exams were excluded. During the study period ...
Source: Journal of Thrombosis and Thrombolysis - March 13, 2019 Category: Hematology Source Type: research

An observational study of the management practices and outcomes of patients with new onset atrial fibrillation in non-cardiothoracic surgeries
Postoperative atrial fibrillation (POAF) is the most common perioperative arrhythmia and its incidence in non-cardiothoracic surgery varies from 0.4% to 21% depending on the population studied.1,2 Traditionally, POAF was considered to be self-limited and have a favorable prognosis, but more recent data have challenged this assumption. POAF is associated with increased in-hospital mortality, length of stay and hospital costs.3,4 More recently few large studies have found that patients who develop postoperative AF have twice higher risk of stroke than those who did not two years after surgical hospitalization, although the i...
Source: Heart and Lung - November 14, 2019 Category: Intensive Care Authors: Mihaela Tiru, Anis John Kadado, Vida Rastegar, Kanval Shah, Kirti K Joshi, Peter Lindenauer, Tara Lagu, Mihaela S Stefan Source Type: research