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Does higher knee hyperextension in patients with hemiplegia affect lateral and medial meniscus volume in the paretic leg? A cross-sectional study
ConclusionsThe knee hyperextension could not be ignored by physicians and needed to be diagnosed and treated as early as possible, the time since hemiplegia could be an indicator of sign of knee hyperextension.
Source: BMC Sports Science, Medicine and Rehabilitation - January 5, 2023 Category: Sports Medicine Source Type: research

Vessel wall magnetic resonance imaging of symptomatic middle cerebral artery atherosclerosis: A systematic review and meta-analysis
CONCLUSION: Based on current evidence, contrast enhancement and T1 hyperintensity on high-resolution MRI have high potential as imaging biomarkers of patients with MCA plaques at risk of ischemic events. Future prospective, longitudinal studies of intracranial-plaque high-resolution MRI are required to improve decision-making for the management of intracranial atherosclerotic plaques.PMID:35952437 | DOI:10.1016/j.clinimag.2022.08.001
Source: Atherosclerosis - August 11, 2022 Category: Cardiology Authors: Rongwei Yang Jiang Yuan Xiuen Chen Xufeng Xie Ziming Ye Chao Qin Source Type: research

Assessing the characteristics and diagnostic value of plaques for patients with acute stroke using high-resolution magnetic resonance imaging
CONCLUSIONS: A larger plaque area and smaller LA in the stenotic MCA, and obvious plaque enhancement might indicate that a patient is prone to acute stroke.PMID:35111645 | PMC:PMC8739121 | DOI:10.21037/qims-21-531
Source: Atherosclerosis - February 3, 2022 Category: Cardiology Authors: Danfeng Zhang Mi Wang Lili Wu Ying Zhao Siyu Wang Xindao Yin Xinying Wu Source Type: research

Criteria for Emergency Brain MRI During Stroke-Alert
Intravenous (IV) tissue plasminogen activator (tPA) should be given to patients with acute ischemic stroke (AIS) and avoided in stroke mimics (SM). Select use of emergency brain magnetic resonance imaging (eMRI-brain) in stroke-alerts aids diagnosis, but accepted utilization criteria for eMRI-brain do not currently exist. We developed criteria for eMRI-brain and report the yield of eMRI-brain in stroke-alert patients.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Evgeny Sidorov, Courtney Iser, Nidhi Kapoor, Bappaditya Ray, Juliane Chainakul, Chao Xu, Andrei V. Alexandrov, David Lee Gordon Source Type: research

Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study
ConclusionIschemic stroke subtypes differ between the two phenotypes. Diabetes and male sex have a stronger association with PCiS than ACiS. Definitive MRI-based PCiS diagnosis aids etiological investigation and contributes additional insights into specific risk factors and mechanisms of injury in PCiS.
Source: Journal of Neurology - November 10, 2019 Category: Neurology Source Type: research

Lower-extremity Dynamometry as a Novel Outcome Measure in a Double-blind, Placebo-controlled, Feasibility Trial of Intravenous Immunoglobulin (IVIG) for HIV-associated Myelopathy
Conclusion: We conclude that an adequately powered clinical trial of IVIG for HIVM would likely require a prolonged recruitment period and multiple participating sites. Lower limb dynamometry is a useful outcome measure for HIVM, which might also be useful in other HIV-related gait disorders. KEYWORDS: Dynamometry, intravenous immunoglobulin (IVIG), human immunodeficiency virus (HIV), myelopathy INTRODUCTION Human immunodeficiency virus (HIV)-associated myelopathy (HIVM) is a rare but well-described neurologic complication of HIV; it was first described early in the acquired immunodeficiency syndrome (AIDS) epidemic, and i...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Current Issue Demyelinating Disease Movement Disorders Neurodegenerative Disease Neurology Original Research Primary Care Technology Trial Methodology Dynamometry human immunodeficiency virus (HIV) intravenous immu Source Type: research

Reflections on the Future of Medicine
Recently, I traveled through China. I climbed mountains, hiked through forests, crossed deep valleys. I visited cities of every size. I floated across lakes and traveled beautiful shorelines churning with life. As a man of a certain age, I began to compare the permanence of the timeless landscape with the evanescence of my own existence. Yet, as a scientist, I knew these reflections were flawed. Scientists are trained to think in terms of aeons, millenia, and lifetimes. Consider the paradox. Is it the solid mountain or fragile the forest that is permanent? Is it the massive shoreline cliffs or the teeming shore life that...
Source: Science - The Huffington Post - January 9, 2017 Category: Science Source Type: news

Isolated MCA Disease in Patients Without Significant Atherosclerotic Risk Factors: A High-Resolution Magnetic Resonance Imaging Study Clinical Sciences
Conclusions— In our cohort of young patients with minimal risk factors, atherosclerosis seems to be an uncommon pathology of middle cerebral artery stenosis. HR-MRI aids us to make a more reliable diagnosis.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Ahn, S.-H., Lee, J., Kim, Y.-J., Kwon, S. U., Lee, D., Jung, S.-C., Kang, D.-W., Kim, J. S. Tags: Pathophysiology, Acute Cerebral Infarction, Other Vascular biology Clinical Sciences Source Type: research

Addition of Hyperacute MRI Aids in Patient Selection, Decreasing the Use of Endovascular Stroke Therapy Clinical Sciences
Conclusions— Implementation of hyperacute MRI protocol decreases the number of endovascular stroke interventions by half. Further investigation of MRI use for patient selection is warranted.
Source: Stroke - January 27, 2014 Category: Neurology Authors: Wisco, D., Uchino, K., Saqqur, M., Gebel, J. M., Aoki, J., Alam, S., George, P., Newey, C. R., Man, S., Tateishi, Y., McNeil, J., Winfield, M., Cheng-Ching, E., Hui, F. K., Toth, G., Bain, M., Rasmussen, P. A., Masaryk, T., Ruggieri, P., Hussain, M. S. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research