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Infectious Disease: Herpes

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Total 419 results found since Jan 2013.

Pilot study of antibodies against varicella zoster virus and human immunodeficiency virus in relation to the risk of developing stroke, nested within a rural cohort in Uganda
ConclusionsThis is the first prospective study to examine a biological measure of exposure to VZV prior to diagnosis of stroke and although we identified no significant association, in this small pilot, with limited characterisation of cases, we cannot exclude the possibility that the virus is causal for a subset. The impact of HIV on risk of stroke has not been well characterised and warrants further study.
Source: Tropical Medicine and International Health - July 23, 2015 Category: Tropical Medicine Authors: Gershim Asiki, Lisa Stockdale, Ivan Kasamba, Tobias Vudriko, Grace Tumwekwase, Tom Johnston, Pontiano Kaleebu, Anatoli Kamali, Janet Seeley, Robert Newton Tags: Original Article Source Type: research

Herpesvirus Infections and Childhood Arterial Ischemic Stroke: Results of the VIPS Study.
CONCLUSIONS: -Herpesviruses may act as a trigger for childhood AIS, even if the infection is subclinical. Antivirals like acyclovir might have a role in the prevention of recurrent stroke if further studies confirm a causal relationship. PMID: 26813104 [PubMed - as supplied by publisher]
Source: Circulation - January 26, 2016 Category: Cardiology Authors: Elkind MS, Hills NK, Glaser CA, Lo WD, Amlie-Lefond C, Dlamini N, Kneen R, Hod EA, Wintermark M, deVeber GA, Fullerton HJ, VIPS Investigators Tags: Circulation Source Type: research

Effects of herpes zoster vaccination and antiviral treatment on the risk of stroke: a systematic review and meta-analysis
ConclusionsThis meta-analysis suggests that the HZV, but not antiviral treatment, decreases the odds of developing stroke.
Source: Frontiers in Neurology - May 17, 2023 Category: Neurology Source Type: research

The Relationship Between Herpes Zoster and Stroke
Abstract Varicella zoster virus (VZV) infects >95 % of the world population. Typically, varicella (chickenpox) results from primary infection. The virus then becomes latent in ganglionic neurons along the entire neuraxis. In immunocompromised individuals, VZV reactivates and causes herpes zoster (shingles), pain, and rash in 1–2 dermatomes. Multiple case reports showed a link between stroke and zoster, and recent studies have emerged which reveal that VZV infection of the cerebral arteries directly causes pathological vascular remodeling and stroke (VZV vasculopathy). In the past few years, several large ep...
Source: Current Neurology and Neuroscience Reports - February 25, 2015 Category: Neuroscience Source Type: research

Stroke Associated With Varicella Zoster Vasculopathy: A Clinicoradiological Profile of 3 Patients
Conclusions: VZ associated vasculopathy may have diverse clinical profile and neuroimaging features. It should be considered as an important and treatable cause of stroke in appropriate clinical settings.
Source: The Neurologist - March 1, 2017 Category: Neurology Tags: Case Report/Case Series Source Type: research

Late-onset Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes Presenting With Auditory Agnosia
Conclusions: MELAS is a disorder with clinical variability. Neuroimaging studies during stroke-like episodes in MELAS can provide significant clues to the underlying disorder. Although patients typically present in childhood, the first stroke-like episode can occur later in life in some patients, potentially related to a lower heteroplasmy level.
Source: The Neurologist - May 1, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research

ASA: Herpes Zoster Vaccine May Reduce Risk for Stroke
WEDNESDAY, Feb. 12, 2020 -- Vaccination with zoster vaccine live (ZVL) is associated with a reduced risk for stroke among older adults, according to a study to be presented at the American Stroke Association International Stroke Conference, held...
Source: Drugs.com - Pharma News - February 12, 2020 Category: Pharmaceuticals Source Type: news

Herpes simplex virus 2 vasculitis as cause of ischemic stroke in a young immunocompromised patient
We report a case of a young woman with a left middle cerebral artery (MCA) ischemic stroke. The patient had history of HIV-1 infection, with periods of therapeutic non-compliance. Initial computed tomography (CT) imaging studies showed stenosis of the M1 segment of the left MCA, and magnetic resonance imaging (MRI) confirmed infarction of the MCA territory. Serial transcranial Doppler ultrasound revealed progressive occlusion of the MCA and stenosis of the left anterior cerebral artery. Systemic investigation for other causes of stroke was normal. Lumbar puncture revealed a mildly inflammatory cerebrospinal fluid, and HSV-...
Source: Journal of NeuroVirology - August 23, 2020 Category: Neurology Source Type: research

HSV-Encephalitis Resembling Acute Cerebral Infarction in a Patient With Atrial Fibrillation: Beware of Stroke Mimics
Conclusion: HSV-encephalitis might occasionally result in the development of unilateral brain MRI lesions with extensive cytotoxic edema, resembling an acute ischemic stroke. Therefore, HSV-encephalitis must be considered in the differential diagnosis of acute ischemic stroke with atypical presentation. The presence of a significant dissociation between the brain MRI lesion volume and the neurological deficits, as well as certain brain MRI imaging discrepancies might serve as “red flags” to extend the diagnostic workup.
Source: The Neurologist - January 1, 2022 Category: Neurology Tags: Case Report/Case Series Source Type: research

Zoster-associated Prothrombotic Plasma Exosomes and Increased Stroke Risk
J Infect Dis. 2022 Oct 6:jiac405. doi: 10.1093/infdis/jiac405. Online ahead of print.ABSTRACTHerpes zoster (HZ, shingles) caused by varicella zoster virus (VZV) reactivation increases stroke risk for up to one-year post-HZ. The underlying mechanisms are unclear, however, the development of stroke distant from the site of zoster (e.g. thoracic, lumbar, sacral) that can occur months after resolution of rash points to a long-lasting, virus-induced soluble factor(s) that can trigger thrombosis and/or vasculitis. Herein, we investigated the content and contributions of circulating plasma exosomes from HZ and non-HZ patient samp...
Source: Herpes - October 6, 2022 Category: Infectious Diseases Authors: Andrew N Bubak Christina Coughlan Janelle Posey Anthony J Saviola Christy S Niemeyer Serena W R Lewis Sara Bustos Lopez Adriana Solano Stephen K Tyring Cassidy Delaney Keith B Neeves Ravi Mahalingam Kirk C Hansen Maria A Nagel Source Type: research

Trend in the Numbers of Hospitalized Patients With Varicella, Herpes Zoster, and Ischemic Stroke in Japanese Individuals & lt;20 Years of Age Before and After Implementation of Universal Varicella Vaccination
Pediatr Infect Dis J. 2023 Mar 20. doi: 10.1097/INF.0000000000003907. Online ahead of print.ABSTRACTSeveral studies have shown an association between varicella-zoster virus infection and ischemic stroke. We analyzed the trends in the numbers of patients with varicella, herpes zoster and ischemic stroke before and after the universal vaccination program using a Japanese database of hospitalized patients. The number of patients with varicella decreased but those of herpes zoster and ischemic stroke did not change.PMID:36996309 | DOI:10.1097/INF.0000000000003907
Source: Herpes - March 30, 2023 Category: Infectious Diseases Authors: Soichiro Ishimaru Nobuaki Michihata Yoshiki Kawamura Kazuaki Uda Hiroki Matsui Kiyohide Fushimi Hideo Yasunaga Tetsushi Yoshikawa Source Type: research

532 Shingles and post-herpetic neuralgia (PHN) in post-stroke patients: Real-world evidence
Shingles, known as zoster or herpes zoster, is a neurotropic viral disease featured with painful dermatomal skin eruptions, which leads to a notorious complication, post-herpetic neuralgia (PHN). PHN are usually refractory to treatment and disturbs patients' life. Among the world, stroke is a main cause of morbidity and mortality. Since patients are prone to get infectious diseases during acute phase following stroke, this study is aimed to investigate whether stroke increases the risk of shingles and it's terrible complication, PHN.
Source: Journal of Investigative Dermatology - April 17, 2023 Category: Dermatology Authors: C. Wu, Y. Lu Source Type: research

Herpes Zoster Linked Again to Increased Stroke, MIHerpes Zoster Linked Again to Increased Stroke, MI
The vaccine that reduces herpes zoster might also cut risks for vascular events, including stroke, transient ischemic attack, and myocardial infarction, researchers speculate. Medscape Medical News
Source: Medscape Cardiology Headlines - January 2, 2014 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news