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Infectious Disease: Herpes

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Total 419 results found since Jan 2013.

GLUTAMATE RECEPTOR ANTIBODIES IN NEUROLOGICAL DISEASES: Anti-AMPA-GluR3 antibodies, Anti-NMDA-NR1 antibodies, Anti-NMDA-NR2A/B antibodies, Anti-mGluR1 antibodies or Anti-mGluR5 antibodies are present in subpopulations of patients with either: Epilepsy, Encephalitis, Cerebellar Ataxia, Systemic Lupus Erythematosus (SLE) and Neuropsychiatric SLE, Sjogren's syndrome, Schizophrenia, Mania or Stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate receptors, decrease glutamate receptor's expression, impair glutamate-induced signaling and function, activate Blood Brain Barrier endothelial cells, kill neurons, damage the brain, induce behavioral/psychiatric/cognitive abnormalities and Ataxia in animal models, and can be removed or silenced in some patients by immunotherapy.
Abstract Glutamate is the major excitatory neurotransmitter of the Central Nervous System (CNS), and it is crucially needed for numerous key neuronal functions. Yet, excess glutamate causes massive neuronal death and brain damage by excitotoxicity-detrimental over activation of glutamate receptors. Glutamate-mediated excitotoxicity is the main pathological process taking place in many types of acute and chronic CNS diseases and injuries. In recent years, it became clear that not only excess glutamate can cause massive brain damage, but that several types of anti-glutamate receptor antibodies, that are present in ...
Source: Herpes - August 1, 2014 Category: Infectious Diseases Authors: Levite M Tags: J Neural Transm Source Type: research

Biological Plausibility of a Link Between Arterial Ischemic Stroke and Infection with Varicella-Zoster Virus or Herpes Simplex Virus.
Abstract There are now 9 human herpesviruses; the increase from 8 to 9 was caused by a recent decision to split human herpesvirus (HHV) strains 6A and 6B into distinct species. The 9 species are subdivided into three subfamilies, called alpha: herpes simplex virus (HSV) types 1 and 2 and varicella-zoster virus (VZV); beta: cytomegalovirus (CMV), HHV6A, HHV6B and HHV7; gamma: Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (sometimes called HHV8). These same herpesviruses have evolved with humankind around the world since the great migration of modern humans across the Mandeb Strait out of Afri...
Source: Circulation - January 26, 2016 Category: Cardiology Authors: Grose C Tags: Circulation Source Type: research

Carotid intima media thickness and blood biomarkers of atherosclerosis in patients after stroke or myocardial infarction.
CONCLUSIONS: Our study supports linear correlations between CIMT and IC and hs-CRP levels. However, these associations seem to depend on the type of vascular burden. PMID: 28051279 [PubMed - in process]
Source: Croatian Medical Journal - December 30, 2016 Category: Journals (General) Authors: Kurkowska-Jastrzebska I, Karlinski MA, Błazejewska-Hyzorek B, Sarzynska-Dlugosz I, Filipiak KJ, Czlonkowska A Tags: Croat Med J Source Type: research

Misdiagnosis of CADASIL: A single Medical Center experience (P1.251)
Conclusions:CADASIL is the most prevalent monogenic cerebral small-vessel arteriopathy. Despite wide availability of genetic testing, misdiagnosis and delay diagnosis are common. We encourage for enhanced awareness of CADASIL among patients with migraines with aura, recurrent TIAs or subcortical ischemic strokes, and mood disorder, in order to provide appropriate multidisciplinary treatment, psychological support and genetic counselingStudy Supported by: n/aDisclosure: Dr. Ortiz-Garcia has nothing to disclose. Dr. Orjuela has nothing to disclose. Dr. Sweis has nothing to disclose. Dr. Biller has received personal compensat...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ortiz-Garcia, J., Orjuela, K., Sweis, R., Biller, J. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Herpes Simplex Laryngitis Presenting as Airway Obstruction in a Stroke Patient
We present the second confirmed report of HSV laryngitis in an adult stroke patient, resulting in complicated airway management issues. This rare presentation of laryngeal HSV in a stroke patient can interfere with speech, language, and swallowing functions and confounds the etiology of these issues, which can impact subsequent management.
Source: IDCases - August 23, 2018 Category: Infectious Diseases Source Type: research

Post-Onset Shingles Rx Fails to Cut Ischemic Stroke Risk Post-Onset Shingles Rx Fails to Cut Ischemic Stroke Risk
The higher risk for stroke with herpes zoster was not attenuated by antivirals or Zostavax vaccination in older patients, but that shouldn ' t slow vaccination rates or further study.Medscape Medical News
Source: Medscape Medical News Headlines - February 1, 2019 Category: Consumer Health News Tags: Cardiology News Source Type: news

Herpes simplex virus encephalitis mimicking acute ischemic stroke
CONCLUSION: HSV infections may mimic stroke and therefore should be included in the differential diagnosis of atypical acute nervous conditions. In neurological events of acute nature, especially in febrile patients whose brain imaging is suspicious or inconclusive, the eventuality of a herpetic encephalitis should be kept in mind. This will lead to a prompt antiviral therapy and to a favorable outcome.PMID:36895212 | PMC:PMC9990771 | DOI:10.25259/SNI_1123_2022
Source: Herpes - March 10, 2023 Category: Infectious Diseases Authors: Ermir Ro çi Stela Dodaj Gentian Vyshka Source Type: research