Kaposi Sarcoma with Musculoskeletal Manifestations in a Well-controlled HIV Patient
We present here a case of relapsed HIV-related Kaposi Sarcoma (KS), manifesting as a plantar ulcer with underlying bone involvement in a patient with well-controlled HIV. Radiographic and magnetic resonance imaging of the patient’s right foot showed bone destruction suggestive of osteomyelitis. However, when a bone biopsy was done, this was consistent with KS, without any signs of bone infection. Patient was initially diagnosed with KS four years prior. He was successfully treated at the time with doxorubicin, radiation therapy, and began HIV therapy. At the time of the KS recurrence, his HIV viral load was undetecta...
Source: IDCases - June 14, 2019 Category: Infectious Diseases Source Type: research

Unusual presentation of Urban Leptospirosis complicated by a Septic Shock
Publication date: Available online 13 June 2019Source: IDCasesAuthor(s): George El Hasbani, Sarmad Riaz Farooqui, Ahmad Kofahi, Yasir Saeed, Omar Tayeh, Mohammad Abu-Hishmeh, Herbeth Moran, Marcelo Troya-Maldonado, Rajan Khanna, Jean-Pierre Assaker, Richard AssakerAbstractLeptospirosis, an infectious zoonosis, is common to tropical areas. The clinical presentation varies from flu-like symptoms to a serious presentation called Weil’s syndrome. Fever and conjunctival suffusion are present in the majority of patients. This case report describes a resident of New York City who presented initially with gastroenteritis sym...
Source: IDCases - June 14, 2019 Category: Infectious Diseases Source Type: research

Fatal Curvularia brain abscess in a heart and kidney transplant recipient
Publication date: Available online 13 June 2019Source: IDCasesAuthor(s): Jose Armando Gonzales Zamora, Yogeeta Varadarajalu (Source: IDCases)
Source: IDCases - June 14, 2019 Category: Infectious Diseases Source Type: research

Community-acquired Escherichia coli meningitis and spondylodiscitis in an adult patient with discoid lupus erythematosus
We describe a case of CA-ECM in Portugal in an adult patient with discoid lupus erythematosus under immunomodulatory therapy. A 73-year-old woman was admitted to the emergency department with fever and altered mental status over 48 hours. Cerebrospinal fluid analysis showed 185 leukocytes/μL, including 85% neutrophils, hypoglycorrhachia (less than 5 mg/dL) and elevated protein of 423 mg/dL with positive culture for Escherichia coli. She was treated with ceftriaxone. Imaging studies also demonstrated spondylodiscitis and arthritis. She responded well to antimicrobial therapy and completed the treatme...
Source: IDCases - June 14, 2019 Category: Infectious Diseases Source Type: research

Corynebacterium striatum Bacteremia Associated with Cellulitis in a Patient with Cirrhosis
We present a rare case of bacteremia due to multidrug resistant Corynebacterium striatum in a 52-year-old male with cirrhosis. The patient had lower extremity cellulitis which likely served as a port of entry. (Source: IDCases)
Source: IDCases - June 13, 2019 Category: Infectious Diseases Source Type: research

Capnocytophaga sputigena: An unusual cause of community-acquired pneumonia
Publication date: Available online 11 June 2019Source: IDCasesAuthor(s): Laurie Gosse, Sophie Amrane, Morgane Mailhe, Grégory Dubourg, Jean-Christophe LagierAbstractCapnocytophaga sputigena is an unusual cause of community-acquired pneumonia. A 22-year-old woman presented an amoxicillin-resistant pneumonia. Sputum examination detected C. sputigena from 3 specimens with a significant bacterial load. The strain produced beta lactamase. Evolution was favorable after introduction of amoxicillin-clavulanate acid. Physicians might be aware of the presence of this unusual bacterium in cases of community-acquired pneumonia. (Source: IDCases)
Source: IDCases - June 13, 2019 Category: Infectious Diseases Source Type: research

Cutaneous leishmaniasis in non-endemic countries: An emerging yet neglected problem
We report a CL case in a 30 year-old man returned from Brazil, with a cutaneous ulcerated lesion, where it was possible to isolate Leishmania braziliensis/guyanensis complex (subgenus Viannia). An initial course of treatment with miltefosine was attempted, but considering the lack of response, liposomal amphotericin B was used, with very good results. Our report highlights the obstacles faced in the diagnosis and treatment of New World CL in non-endemic countries and the need for more funding and research. (Source: IDCases)
Source: IDCases - June 13, 2019 Category: Infectious Diseases Source Type: research

Colonic basidiobolomycosis presenting with intestinal obstruction and a normal eosinophil count
We report a middle aged patient who was admitted to hospital with suspected metastatic colonic carcinoma. He presented with constipation, anorexia and weight loss. Computed tomography scan disclosed a mass involving the mid and distal sigmoid colon and hypodense lesion in hepatic segment IV. Excised tissue during a Hartmann’s surgery showed an extensive eosinophil-rich transmural inflammation with mural necrotizing granulomas and several broad septated fungal hyphae. He was commenced on voriconazole following surgery. The diagnosis of basidiobolomycosis was established by histopathological examination. Since the diag...
Source: IDCases - June 1, 2019 Category: Infectious Diseases Source Type: research

Possible canine source of Streptococcus equi subspecies zooepidemicus causing meningitis in an infant
We report a case of a six-month-old female patient who presented with a one-day history of fevers and neurological symptoms. Blood and cerebrospinal fluid cultures revealed S. zooepidemicus, and brain imaging showed a subdural fluid collection and diffuse brain infarcts. Exposure history suggested a canine source as patient had close contact with two dogs that had respiratory infections but no contact with other pets including horses. She had clinical and radiographic improvement after a four-week course of penicillin G and drainage of a subdural fluid collection but she had residual severe to profound hearing loss and mil...
Source: IDCases - June 1, 2019 Category: Infectious Diseases Source Type: research

Disseminated cryptococcal infection in a patient with treatment-naïve chronic lymphocytic leukemia (CLL)
We report a case of disseminated cryptococcosis in a treatment-naïve chronic lymphocytic leukemia (CLL) patient. A 60-year-old man presented with a two-week history of intermittent fevers, frontal headaches, night sweats, weight loss and multiple pink papules on hands and face. Cryptococcemia was found by blood culture unexpectedly. Further investigation confirmed cryptococcal meningitis and skin disease. He responded to two week amphotericin B and flucytosine followed by four-week amphotericin B and fluconazole, three-month high dose fluconazole (800 mg/day), and maintenance fluconazole (400 mg/day) the...
Source: IDCases - June 1, 2019 Category: Infectious Diseases Source Type: research

Listeria Brain Abscess in a Patient with Autoimmune Hepatitis
Publication date: Available online 31 May 2019Source: IDCasesAuthor(s): Polina Trachuk, Tania Marin Saquicela, Michael Levi, Rabea KhedimiAbstractListeria monocytogenes is an uncommon cause of brain abscesses. Immunocompromised hosts, pregnant women and patients at extremes of age are especially susceptible. We discuss the successful management of a woman with autoimmune hepatitis on prednisone and azathioprine therapy with a L. monocytogenes brain abscess. Previously thought to be a rare cause of central nervous system (CNS) infection, the incidence of CNS listeriosis has increased due to a rise in organ and bone marrow t...
Source: IDCases - June 1, 2019 Category: Infectious Diseases Source Type: research

Aspergillosis Myocarditis in the Immunocompromised Host
Publication date: Available online 31 May 2019Source: IDCasesAuthor(s): Sean S. Bullis, Alison Krywanczyk, Andrew J. HaleABSTRACTInvasive cardiac aspergillosis has been rarely described in immunocompromised patients. This disease is difficult to diagnose by conventional laboratory, microbiologic, and imaging techniques, and is often recognized only post-mortem. The authors present the case of a 60-year-old woman admitted with an exacerbation of eosinophilic granulomatosis with polyangitiis (EGPA) who subsequently died from Aspergillus myocarditis, and compare the patient’s case to prior literature. This serves as an ...
Source: IDCases - June 1, 2019 Category: Infectious Diseases Source Type: research

A rare neurological complication of tuberculosis: Transverse myelitis
We present a patient with tuberculosis presenting with meningitis and transverse myelitis who had marked clinical improvement and neurologic recovery after treatment of tuberculosis and intravenous steroid pulses. (Source: IDCases)
Source: IDCases - May 25, 2019 Category: Infectious Diseases Source Type: research

Infective Endocarditis and Brain Abscess Secondary to Aggregatibacter aphrophilus
We report a case of a 53-year-old male with no significant past medical history who developed acute infective endocarditis complicated by a brain abscess caused by A. aphrophilus. The patient underwent aspiration of the abscess and treated with a long course of intravenous antimicrobials. This case represents a rare complication of infective endocarditis caused by A. aphrophilus and to the best of our knowledge, is the second reported case in the literature describing such a complication in a previously healthy patient. Although neurological sequela is associated with higher mortality and may be the presenting symptom of i...
Source: IDCases - May 19, 2019 Category: Infectious Diseases Source Type: research

Septic shock secondary to an acute necrotizing community-acquired pneumonia with bacteremia due to Pseudomonas aeruginosa
Publication date: Available online 16 May 2019Source: IDCasesAuthor(s): P. Riviere, D. Patin, E. Delaporte, H. Mahfoudi, S. Lecailtel, F. Poher, P. Villette, J. Duclaux, P. Jouault, G. BruninAbstractPseudomonas aeruginosa is an uncommon cause of necrotizing acute community-acquired pneumonia (CAP). Only thirteen cases have been previously reported in the literature. In this article, we describe a case of previously healthy 80-year-old male patient, who presented in septic shock caused by necrotizing CAP. Despite inadequate empiric antimicrobial treatment, the patient survived and was able to return to his home after three ...
Source: IDCases - May 16, 2019 Category: Infectious Diseases Source Type: research

Stenotrophomonas maltophilia Right‐Sided Endocarditis in an Adult Patient with Uncorrected Congenital Heart Disease
Publication date: Available online 14 May 2019Source: IDCasesAuthor(s): Mohammadbagher Sharifkazemi, Mohammadhassan Nemati, Alireza Moarref (Source: IDCases)
Source: IDCases - May 15, 2019 Category: Infectious Diseases Source Type: research

Cutaneous digital tuberculosis in immunocompetent host
Publication date: Available online 15 May 2019Source: IDCasesAuthor(s): A. Redor, A. Baeke, K. Costa, K. Bertrand, M. Saada, H. Aumaitre (Source: IDCases)
Source: IDCases - May 15, 2019 Category: Infectious Diseases Source Type: research

Xanthogranulomatous Prostatitis presenting as Pseudomonas aeruginosa Prostatic Abscesses: An Uncommon Complication after Kidney Transplantation
Publication date: Available online 10 May 2019Source: IDCasesAuthor(s): Sara Belga, Will Chen, Gavin Low, Carlos CerveraAbstractXanthogranulomatous (XG) prostatitis is a rare form of granulomatous prostatitis characterized by a benign inflammatory process of non-specific etiology that clinically may mimic carcinoma. Few cases have been reported in the English language medical literature, with only four reported cases presenting as prostatic abscesses. A 70-year-old male with type 2 diabetes mellitus and two previous kidney transplants presented with septic shock secondary to Pseudomonas aeruginosa bacteremia 4 days after u...
Source: IDCases - May 11, 2019 Category: Infectious Diseases Source Type: research

Necrotizing fasciitis of the finger
Publication date: Available online 10 May 2019Source: IDCasesAuthor(s): Albadri Zeyad, Kutaiba SalmanAbstractA 62 year old woman with a medical history of hypertension presented to her local general practice with moderate pain in the right ring finger which worsened over a few hours after onset. Her condition progressed swiftly into sepsis and required hospital admission in the intensive care unit. Over the course of 24 hours the patient was diagnosed with necrotizing fasciitis in the finger but unfortunately despite treatment with antimicrobials and surgical debridement the patient’s finger could not b...
Source: IDCases - May 11, 2019 Category: Infectious Diseases Source Type: research

Major risk factors for leprosy in a non-endemic area of the United States: A Case Series
We present three cases (two foreign born and one autochthonous case) from Hillsborough county Florida, that were reported from this non-endemic area during the past five years. The first case was a 35-year-old male from Mexico, with history of exposure from a Haitian inmate, who presented with multiple erythematous non-tender cutaneous lesions and numbness in both hands. Biopsy confirmed borderline lepromatous leprosy. The second case was a 34-year-old male, from Florida who presented with sparse annular non-supporative lesions on left cheek with one-month duration and denied leprosy or armadillo exposure. Biopsy confirmed...
Source: IDCases - May 10, 2019 Category: Infectious Diseases Source Type: research

Chronic enteroviral meningoencephalitis in a patient on rituximab for the treatment of psoriatic arthritis: a case report and brief literature review
Publication date: Available online 9 May 2019Source: IDCasesAuthor(s): Roberto Tellez, Allison M. Lastinger, Jeffery P. HoggAbstractEnteroviruses are RNA viruses within the Picornaviridae family. Enteroviruses derive their name from the way they are typically transmitted via the intestinal tract. They commonly infect millions of people every year and often do not cause severe disease in immunocompetent patients with few exceptions. Aseptic meningitis is a classic manifestation and is usually self-limited, however, can lead to severe neurological complications in an immunocompromised individual. It has been well-described t...
Source: IDCases - May 10, 2019 Category: Infectious Diseases Source Type: research

Campylobacter jejuni bacteremia in a patient with asplenia and enteritis
Publication date: Available online 9 May 2019Source: IDCasesAuthor(s): Ramírez IsabelAbstractCampylobacter bacteremia is an unusual presentation of a common infectious disease such as enteritis. We provide key teaching points about its presentation, risk factors, diagnosis and treatment. (Source: IDCases)
Source: IDCases - May 10, 2019 Category: Infectious Diseases Source Type: research

Endocarditis caused by Stenotrophomonas maltophilia—A rare presentation of an emerging opportunistic pathogen
This report will further explore the unique presentation of this pathogen along with its epidemiology, resistance mechanisms, risk factors for infection, diagnosis, and appropriate antimicrobial treatment. (Source: IDCases)
Source: IDCases - May 10, 2019 Category: Infectious Diseases Source Type: research

Pyometra due to Pseudomonas aeruginosa
In this report we describe pyometra due to Pseudomonas aeruginosa in a 90-year-old woman who presented with abdominal pain, nausea with emesis and diarrhea. She was evaluated at an outside emergency department and computed tomography (CT) revealed a large, complex, cystic mass measuring 9.2 centimeters (cm) in greatest diameter. Given her age, the diagnosis of malignancy was entertained. She was referred to gynecologic-oncology service for evaluation and underwent exploratory laparotomy with total abdominal hysterectomy and lysis of adhesions. Intraoperative findings were consistent with pyometra. Cultures ultimately grew ...
Source: IDCases - May 8, 2019 Category: Infectious Diseases Source Type: research

Febrile urinary tract infection in an immunocompetent male caused by Burkholderia multivorans- evidence of transmission in a home hot tub
Publication date: Available online 3 May 2019Source: IDCasesAuthor(s): Magnus Rasmussen, Karl OldbergAbstractBurkholderia are opportunistic pathogens. Here we describe a case of Burkholderia multivorans urinary tract infection in a previously healthy man. The bacterium was likely introduced during sexual intercourse in a home hot tub contaminated with the bacterium. The infection led to urinary retention and was successfully treated with trimethoprim-sulfamethoxazole. (Source: IDCases)
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

West Nile Virus infection in a renal transplant recipient resulting in polioencephalomylelitis, quadriplegia, and global brain atrophy
This report highlights the catastrophic complications of WNV in an immunocompromised host. (Source: IDCases)
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

Trivalvular Infective Endocarditis secondary to Granulicatella adiacens and Peptostreptococcus spp
We present a case of a 42-year-old Caucasian man that came to our facility complaining of dyspnea and subjective fevers and was found to have infective endocarditis. His blood cultures initially grew Peptostreptococcus spp and he was started on penicillin and gentamicin. Repeat blood cultures, drawn 48 hours later, became positive for Granulicatella adiacens. Vancomycin was added at this point, given reports of growing penicillin resistance of Granulicatella spp. Transthoracic echocardiogram showed multiple vegetations on the aortic, mitral and tricuspid valves. The patient’s final antibacterial regimen consis...
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

Acute flaccid myelitis associated with enterovirus D68 in a non-epidemic setting
This report indicates that AFM caused by EV-D68 can arise even in non-epidemic situations. If a patient presents with paralysis, AFM caused by EV-D68 should be included in the differential diagnosis, regardless of the absence of an epidemic of EV-D68 infection. (Source: IDCases)
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

Pellagra in isoniazid preventive and antiretroviral therapy
Publication date: Available online 3 May 2019Source: IDCasesAuthor(s): John Koech Kipsang, Joseph K. Choge, Pamela A. Marinda, Christopher Khayeka-WandabwaAbstractPellagra is caused by cellular deficiency of niacin or its precursor amino acid, tryptophan. Isoniazid preventive therapy (IPT) is the administration of isoniazid (INH) to latent tuberculosis (TB) infection affected people preventing advancement to active TB disease. Although potentially life-saving for human immunodeficiency virus (HIV)-infected people with no active TB, IPT is arguably a possible player in pellagra in addition to well-known malnourishment deter...
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

Hypermucoviscous Klebsiella pneumoniae: A challenge in community acquired infection
We present four cases of bacteremia and liver abscesses secondary to hypervirulent K. pneumoniae, two of them associated with endophthalmitis. K. pneumoniae isolates recovered from two of the patients belonged to capsular serotype K1 (genes wzx_K1 and magA), while the other two were K2 (gene wzy_K2). Both of the K1 isolates were classified into a ST23, and isolates of serotype K2 belonged to the ST375 and ST881 clones.In Europe, hvKP isolates are less frequently recovered, mostly associated with Asian citizens or travelers, which was not the case in our patients. K1 capsular serotype is a major cause of primary liver absce...
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

Cutibacterium avidum: a rare but expected agent of breast implant infection
We present a 50-year-old woman with Cutibacterium avidum infection associated with breast implant augmentation, which required the removal of the implants to achieve the cure.As a skin commensal, Cutibacterium avidum previously was considered of low pathogenicity, but is now recognized as a causative organism of serious spontaneous and surgical site infections. It should not be routinely disregarded without further investigation, particularly if clinical signs of infection are present. (Source: IDCases)
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

Cytomegalovirus colitis in a patient with HIV infection shortly after initiation of antiretroviral therapy
Publication date: Available online 4 May 2019Source: IDCasesAuthor(s): Shinji Yoshida, Nobuaki Mori, Miwako Honda (Source: IDCases)
Source: IDCases - May 4, 2019 Category: Infectious Diseases Source Type: research

Escherichia coli endocarditis of a native mitral valve
Publication date: Available online 3 May 2019Source: IDCasesAuthor(s): Ana Rita Nogueira, Sofia Brazão, Diana Ferreira, António Aragão, Manuel Teixeira Veríssimo, Armando CarvalhoAbstractEscherichia coli (E.coli) is a rare cause of endocarditis, although is a common causative agent of bacteremia. An 89-year-old woman presented with recurrent episodes of fever and persistent E. coli bacteremia with 3-month duration, despite antimicrobial therapy. At first, a urinary tract infection was diagnosed and later a mycotic aneurysm of the abdominal aorta was found and required an endovascular repair. The...
Source: IDCases - May 3, 2019 Category: Infectious Diseases Source Type: research

Severe imported malaria in an intensive care unit: A Case Series
ConclusionThe median treatment delay of seven days explains why these patients ended in intensive care with multiple symptoms of severe malaria and often multiorgan failure. Pretravel advice and use of malaria chemoprophylaxis when visiting high risk areas would probably have prevented infection and timely attendance to healthcare once symptomatic would have reduced the morbidity associated with infection, reduced length of stay in hospital and hence resources. (Source: IDCases)
Source: IDCases - May 2, 2019 Category: Infectious Diseases Source Type: research

HIV Adult with Fever and Shortness of Breath: Influenza B Misdiagnosed as Pneumocystis (carinii) jiroveci pneumonia (PCP)
We present a case of an elderly female with HIV on HAART who presented with shortness of breath assumed to have Pneumocystis (carinii) jiroveci pneumonia (PCP) even though she had a clinical diagnosis of influenza B. She was thought to have PCP only because she had HIV. Tests for PCP were negative including BAL staining. Influenza B present in her respiratory secretions by PCR and was also cultured from BAL fluid. Diagnostic associations are helpful in suggesting diagnostic possibilities but must be supported by clinical correlation of characteristic clinical features. (Source: IDCases)
Source: IDCases - April 29, 2019 Category: Infectious Diseases Source Type: research

Mycobacterium abscessus Periprosthetic joint infection following bilateral Total Knee arthroplasty
We report a case of difficult diagnosis of bilateral PJI caused by Mycobacterium abscessus, following bilateral total knee arthroplasty in an elderly male, but treated successfully despite prolonged infection. M. abscessus complex comprises a group of rapidly growing, multidrug-resistant NTM, capable of forming biofilms on prostheses, responsible for wide spectrum of hospital acquired infections. M. abscessus as a cause of PJI is not reported widely. There are a few cases described in literature worldwide. There are no policy guidelines available for treating such cases. High clinical suspicion, with a concerted effort to ...
Source: IDCases - April 25, 2019 Category: Infectious Diseases Source Type: research

Salmonella Neck Abscess in a Diabetic
We describe a case of Salmonella neck abscess in a diabetic patient. An 18 year old diabetic male was admitted with increasing left sided neck pain and swelling approximately four weeks after gastrointestinal illness. Imaging revealed a left sided neck abscess. Surgical drainage was undertaken. Cultures grew non-typhoid Salmonella species. He was treated with intravenous antibiotics and did well clinically. Salmonella infection should be considered in the differential diagnosis of patients with immunocompromising conditions presenting with neck abscess of unclear etiology. (Source: IDCases)
Source: IDCases - April 20, 2019 Category: Infectious Diseases Source Type: research

Oxacillin-induced leukocytoclastic vasculitis
Publication date: Available online 17 April 2019Source: IDCasesAuthor(s): Meric Mericliler, Andrew MoracoAbstractLeukocytoclastic vasculitis (LCV) refers to a histopathological pattern of neutrophil predominant inflammatory process of small vessels associated with fibrinoid necrosis. Cutaneous LCV usually presents as symmetrically distributed palpable purpuric nodules of the lower extremities with or without systemic involvement. Although 50% of LCV cases are idiopathic, it can be secondary to identifiable causes such as malignancy, autoimmune conditions, infections, and medications. Medications have been implicated in up ...
Source: IDCases - April 18, 2019 Category: Infectious Diseases Source Type: research

Bezold’s Abscess: A Rare Complication of Suppurative Mastoiditis
We describe a patient with recurrent bilateral otalgia who had received multiple courses of antimicrobials who presented with severe headache, neck pain and right sided hearing loss. Imaging studies showed chronic mastoiditis and formation of a Bezold’s abscess. Drainage was performed but symptoms persisted. Our report highlights the need for further evaluation of patients presenting with complicated mastoiditis and the need for prolonged antimicrobial therapy. (Source: IDCases)
Source: IDCases - April 18, 2019 Category: Infectious Diseases Source Type: research

Editorial Board
Publication date: 2019Source: IDCases, Volume 16Author(s): (Source: IDCases)
Source: IDCases - April 17, 2019 Category: Infectious Diseases Source Type: research

Disseminated tuberculosis and hemophagocytic syndrome although TB prophylaxis in patients with inflammatory bowel disease treated with Infliximab
ConclusionTuberculosis must always be considered in the differential diagnosis of hemophagocytic lymphohistiocytosis and acute respiratory failure despite correct prior prophylaxis. (Source: IDCases)
Source: IDCases - April 17, 2019 Category: Infectious Diseases Source Type: research

Invasive pulmonary aspergillosis and pulmonary tuberculosis in a patient treated with infliximab for Crohn’s disease
We report a case of concurrent development of active pulmonary tuberculosis and invasive pulmonary aspergillosis (IPA) in a patient who received therapy with infliximab for Crohn’s disease. He has been treated with antitubercular therapy and liposomal amphotericin B for 8 weeks. His clinical course was complicated by paroxysmal atrial fibrillation requiring maintenance therapy with amiodarone, respiratory failure due both to pneumonia caused by methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamases (ESBL)-producing Klebsiella pneumoniae and pleural effusion requiring chest drainage. ...
Source: IDCases - April 17, 2019 Category: Infectious Diseases Source Type: research

Legionnaire’s Disease Presenting with Encephalitis, Myoclonus, and Seizures: Successful Treatment with Doxycycline
Publication date: Available online 17 April 2019Source: IDCasesAuthor(s): Burke A. Cunha, Bertamaria Dieguez, Nonso OsakweAbstractLegionnaire’s disease (LD) is a non-zoonotic atypical community acquired pneumonia (CAP) with several characteristic extra-pulmonary findings. Pending diagnostic test results, selected characteristic findings when considered together are the basis of clinical syndromic diagnosis and the basis of empiric antimicrobial therapy. Of the extra-pulmonary manifestation of LD, neurologic findings are among the most common, e.g., headache, mental confusion. In LD, encephalitis is rare as are myoclo...
Source: IDCases - April 17, 2019 Category: Infectious Diseases Source Type: research

Capnocytophaga sputigena bacteremia in a neutropenic host
We present a case of a febrile neutropenic patient with mucositis presenting with C. sputigena bacteremia. (Source: IDCases)
Source: IDCases - April 14, 2019 Category: Infectious Diseases Source Type: research

Endocarditis caused by Bartonella Quintana, a rare case in the United States
We report a case of 37-year-old African man, with culture negative endocarditis, emboli and rising B. quintana and B. henselae IgG titers. B. quintana DNA was subsequently detected from the mitral valve sample with 16S rRNA gene and ribC primer sets. Eventually, blood culture for B. quintana was positive after 21 days. Patient was successfully treated with doxycycline and gentamicin. There have been a few cases of B. quintana endocarditis in the USA and most of them were associated with HIV infection, homelessness or alcoholism. The case reported here highlights the importance of high clinical suspicious for Bartonella spe...
Source: IDCases - April 7, 2019 Category: Infectious Diseases Source Type: research

CHRONIC Alcohol ABUSE and spontaneous clearance of hepatitis C virus
We reported a rare case of a 41-year-old male patient infected with HCV genotype 3a who presented spontaneous viral elimination after increasing his daily consumption of alcoholic beverage. In this short review, we overview how modulation of the hepatic inflammatory response could have a role in the viral elimination process. (Source: IDCases)
Source: IDCases - April 7, 2019 Category: Infectious Diseases Source Type: research

Lumbar Tinea Versicolor and Spinal Anaesthesia
We reported a parturient who had generalized tinea versicolor at the lumbar area, safely anaesthetized under spinal anaesthesia through meticulous antiseptic skin preparation who required delivery by caesarean section. (Source: IDCases)
Source: IDCases - March 31, 2019 Category: Infectious Diseases Source Type: research

Endemic Bot Fly Larvae Infection in Northern New York State
Publication date: Available online 28 March 2019Source: IDCasesAuthor(s): Andrew J. Hale, Blaine Mathison, Bobbi Pritt, Keith CollinsAbstractTropical botfly infection is well described, though endemic botfly myiasis in humans is rare in temperate regions. Reported is a case of myiasis from Cuterebra botfly larvae in a man from northern New York with no tropical travel. The authors discuss the epidemiology, life-cycle, and diagnosis of non-tropical botfly infection. (Source: IDCases)
Source: IDCases - March 29, 2019 Category: Infectious Diseases Source Type: research

Non-O1, non-O139 Vibrio cholerae bacteremia in an urban academic medical center in the United States
We report a case of a patient with liver cirrhosis and chronic venous insufficiency who was found to have NOVC bacteremia. The patient had recently visited Florida, USA but had no seafood consumption or exposure to aquatic environments. The patient was managed with antimicrobials, with a favorable outcome. (Source: IDCases)
Source: IDCases - March 28, 2019 Category: Infectious Diseases Source Type: research

Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker
We report a case of Mycobacterium chimaera pulmonary infection in a healthcare worker who presented with cough, low grade fever and weight loss with evidence of a lung mass that was initially thought to be a tumor on CT scan imaging. The patient underwent partial left lung lobectomy and pathology revealed necrotizing granulomas with acid fast bacilli and a culture grew M. chimaera. The patient received combination antimycobacterial therapy according to susceptibility results for twelve months with complete resolution of his symptoms and radiographic findings.Infection Control investigation could not find a source of infect...
Source: IDCases - March 27, 2019 Category: Infectious Diseases Source Type: research