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The Changing Epidemiology of Stroke in Acquired Immune Deficiency Syndrome (AIDS). (I7-1A)
Conclusions:There is an increased frequency of AIDS among stroke patients, possibly due to the increased detection of AIDS. In the HAART era, the median age of incident stroke in AIDS has increased. Whether HAART can reduce the incidence and improve survival of stroke needs to be explored.Disclosure: Dr. Kucab has received personal compensation for activities with Bayer HealthCare as an advisory board participant. Dr. Bhattacharya has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kucab, P., Bhattacharya, P. Tags: The Global Burden of Neurological Infections: Epidemiology, Treatment, and Prevention Data Blitz Presentations Source Type: research

The Changing Epidemiology of Stroke in Acquired Immune Deficiency Syndrome (AIDS). (P1.089)
Conclusions:There is an increased frequency of AIDS among stroke patients, possibly due to the increased detection of AIDS. In the HAART era, the median age of incident stroke in AIDS has increased. Whether HAART can reduce the incidence and improve survival of stroke needs to be explored.Disclosure: Dr. Kucab has received personal compensation for activities with Bayer HealthCare as an advisory board participant. Dr. Bhattacharya has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kucab, P., Bhattacharya, P. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

Exploring Stroke Risk Factors and Outcomes in Sexual and Gender Minority People
Discussion SGM people may have different risk factors, different mechanisms of stroke, and higher risk of recurrent stroke compared with non-SGM people. Standardized collection of sexual orientation and gender identity would enable larger studies to further understand disparities, leading to secondary prevention strategies.
Source: Neurology Clinical Practice - January 18, 2023 Category: Neurology Authors: Diaz, M. A., Rosendale, N. Tags: Research Article Source Type: research

The associations of increased cerebral small vessel disease with cognitive impairment in neurosyphilis presenting with ischemic stroke
ConclusionsCerebral small vessel disease loads in neurosyphilis patients presenting with ischemic stroke are independently associated with acute cognitive impairment and have a prospective value for post-stroke cognitive outcomes.
Source: Brain and Behavior - May 17, 2021 Category: Neurology Authors: Lei Xiang, Tao Zhang, Biao Zhang, Chao Zhang, Shuping Hou, Wei Yue Tags: ORIGINAL RESEARCH Source Type: research

Positive syphilis serology contributes to intracranial stenosis in ischemic stroke patients
ConclusionsSyphilis infection, especially when less well controlled, may play an important role in intracranial stenosis of ischemic stroke patients.
Source: Brain and Behavior - October 21, 2020 Category: Neurology Authors: Lei Xiang, Tao Zhang, Biao Zhang, Chao Zhang, Wanzhen Cui, Wei Yue Tags: ORIGINAL RESEARCH Source Type: research

Frequency of Screening and Prevalence of Neurosyphilis in Stroke Population
Conclusion: Positive syphilis serology is frequent in patients with acute stroke/TIA in our region. Acute post-stroke CSF abnormalities make the diagnosis of NS difficult in the context of CSF VDRL negative.Cerebrovasc Dis
Source: Cerebrovascular Diseases - June 22, 2020 Category: Neurology Source Type: research

Anabolic Steroids Abuse And Ischemic Stroke: A Case Report And Literature Review (P6.247)
CONCLUSIONS:Due to new upcoming socio-behavioral aspects of adolescents and young adults life, neurologists should be screen this unusual risk factor in young patients with stroke.Study Supported by:Disclosure: Dr. Xiong has nothing to disclose. Dr. Velez has nothing to disclose. Dr. Khanna has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Xiong, G., Velez, A., Khanna, A. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Stroke in a Young Patient: A Sentinel Presentation of Neurosyphilis and HIV (P2.109)
Conclusions: Neurosyphilis should be a diagnostic consideration in young patients with ischemic stroke. Clinicians should be aware of the high incidence of concomitant syphilis and HIV in at-risk populations. Effort should be made to inquire about high-risk behaviors and initiate testing for these infections early in the diagnostic workup to avoid missing these crucial diagnoses.Disclosure: Dr. Flaherty has nothing to disclose. Dr. Cutting has received personal compensation for activities with F1000.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Flaherty, E., Cutting, S. Tags: Cerebrovascular Disease and Interventional Neurology: Childhood and Young Adult Source Type: research

Small vessel occlusion and syphilis in patients with first-ever ischemic stroke
Conclusion: The current study showed that the frequency of positive syphilis serological test was higher in patients with first-ever ischemic stroke and SVD as the potential causal mechanism. This finding could be related to the endothelial dysfunction occurring in syphilis.RESUMO Introdu ção: A sífilis é uma doença endêmica, especialmente em países de baixa e média renda, com acometimento vascular descrito em grandes vasos (aortite), porém nenhuma relação clara foi reconhecida em paciente com acidente vascular cerebral, exceto para aqueles com sífilis meningovascular. O bjetivos: Investigar a relação entre h...
Source: Arquivos de Neuro-Psiquiatria - March 19, 2021 Category: Neurology Source Type: research

Stroke and syphilis: A retrospective study of 53 patients.
CONCLUSION: A diagnosis of syphilitic stroke should be suspected in young patients as a manifestation of syphilis, and tests for neurosyphilis should be routine in neurology departments to make a prompt diagnosis, thereby preventing psychological sequelae. PMID: 29631855 [PubMed - as supplied by publisher]
Source: Revue Neurologique - April 12, 2018 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Acute ischemic stroke in a young female: a novel presentation of anti-GAD autoimmunity (P3.272)
Conclusions:Restricted diffusion, seen typically in ischemia, indicates cytotoxic oedema and irreversible cell damage. In this patient, we postulate a mechanism of severe CNS inflammation with cellular toxicity and small vessel vasculitis. Anti-GAD autoimmunity should be considered in young patients presenting with stroke-like episodes, particularly when accompanied by positive phenomenon.Disclosure: Dr. Neo has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Neo, X. S., Lee, K. E., Lee, R. Tags: Cerebrovascular Disease Case Reports II Source Type: research

The Great Imitator—Still Today! A Case of Meningovascular Syphilis Affecting the Posterior Circulation
We describe clinical features and imaging studies of a 50-year-old patient with Parinaud syndrome and a syphilitic dorsal midbrain infarction. Brain magnetic resonance imaging indicated vasculitis of the posterior circulation. The diagnosis of meningovascular syphilis was established by serum and cerebrospinal fluid examinations. Although rare, because of the high impact on treatment, clinicians should always be aware of meningovascular syphilis in the differential diagnosis of stroke, particularly in young and male patients with cryptogenic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 2, 2014 Category: Neurology Authors: Jochen Bäuerle, Anna Zitzmann, Karl Egger, Stephan Meckel, Cornelius Weiller, Andreas Harloff Tags: Case Report Source Type: research

Epidemiology of Acquired Immune Deficiency Syndrome and Cerebrovascular Disease in a Post Antiretroviral Era
People with acquired immune deficiency syndrome (AIDS) develop ischemic stroke through distinct mechanisms. These include infections such as syphilis, tuberculosis, varicella, and other conditions such as cocaine abuse, endocarditis, and hypercoagulability. The effect of improved awareness, detection, and treatment with highly active antiretroviral therapy (HAART) on the incidence and outcome of AIDS patients with stroke is unknown.
Source: Journal of Stroke and Cerebrovascular Diseases - February 7, 2017 Category: Neurology Authors: Phillip Kucab, Pratik Bhattacharya Source Type: research

Infectious Etiologies of Stroke
Semin Neurol 2019; 39: 482-494 DOI: 10.1055/s-0039-1687915Central nervous system (CNS) infections are a frequently underappreciated potential etiology of cerebrovascular disease. Highlighted in this review are a selection of infectious agents that lead to cerebrovascular complications through various mechanisms including multifocal vasculopathy, focal infiltrative vasculitis and vasospasm, and direct vessel wall invasion and thrombus formation. Diagnosis of stroke due to underlying CNS infection requires a high index of clinical suspicion and careful consideration of neuroimaging, serum, and cerebrospinal fluid studies in ...
Source: Seminars in Neurology - September 17, 2019 Category: Neurology Authors: Shulman, Julie G. Cervantes-Arslanian, Anna M. Tags: Review Article Source Type: research

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