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Nontraumatic spontaneous intracerebral hemorrhage: Baseline characteristics and early outcomes
ConclusionThe present study showed that SICH is a serious disease causing high mortality and disability, particularly in the early period after event.
Source: Brain and Behavior - January 12, 2020 Category: Neurology Authors: Mohamed Al ‐Khaled, Samer Awwad, Toralf Brüning Tags: ORIGINAL RESEARCH Source Type: research

Thrombolysis safety and effectiveness in acute ischemic stroke patients with pre-morbid disability
ConclusionPatients with mRS 2 and 3 may benefit from rt-PA with a moderate risk of sICH and mortality.
Source: Journal of Clinical Neuroscience - December 25, 2019 Category: Neuroscience Source Type: research

Recanalization is the Key for Better Outcome of Thrombectomy in Basilar Artery Occlusion
ConclusionReperfusion is the major predictor of functional outcome in BAO in clinical practice. Failed recanalization resulted in a  13-fold increase of the risk of poor outcome. Successful recanalization is crucial to achieve a better functional outcome in BAO.
Source: Clinical Neuroradiology - December 22, 2019 Category: Neurology Source Type: research

Nontraumatic spontaneous intracerebral hemorrhage: Baseline characteristics and early outcomes
ConclusionThe present study showed that SICH is a serious disease causing high mortality and disability, particularly in the early period after event.
Source: Brain and Behavior - December 14, 2019 Category: Neurology Authors: Mohamed Al ‐Khaled, Samer Awwad, Toralf Brüning Tags: ORIGINAL ARTICLE Source Type: research

Collateral Scores in Acute Ischemic Stroke
ConclusionAlthough collaterals are known to correlate with clinical outcome, none of the analyzed collateral scores sufficiently predicted outcome as a  standalone parameter.
Source: Clinical Neuroradiology - November 27, 2019 Category: Neurology Source Type: research

Direct Admission vs. Secondary Transfer to a  Comprehensive Stroke Center for Thrombectomy
ConclusionThese results confirm prior studies stating that DA to a  comprehensive stroke center leads to better outcome compared to ST in stroke patients undergoing thrombectomy.
Source: Klinische Neuroradiologie - October 10, 2019 Category: Radiology Source Type: research

Decompressive craniectomy in malignant middle cerebral artery infarction: family perception, outcome and prognostic factors.
CONCLUSIONS: We present a 21 patients group where the best outcome was achieved in patients ≤60 years old. The severe neurological sequelae in patients with malignant infarction subjected to decompressive hemicraniectomy are tolerated and accepted by most families to the benefit of survival. We must not let this family satisfaction hide the prognosis, having to contextualize it within the real ambulatory situation of the patients. PMID: 31445797 [PubMed - as supplied by publisher]
Source: Neurocirugia - August 20, 2019 Category: Neurosurgery Authors: García-Feijoo P, Isla A, Díez-Tejedor E, Mansilla B, Palpan Flores A, Sáez-Alegre M, Vivancos C Tags: Neurocirugia (Astur) Source Type: research

Total Small Vessel Disease Burden Predicts Functional Outcome in Patients With Acute Ischemic Stroke
Conclusion: Total SVD burden negatively associated with functional outcome at 3 months in patients with acute ischemic stroke and is superior to individual SVD feature in prediction of functional outcome. MRI-based assessment of total SVD burden is highly valuable in clinical management of stroke victims, and could help guide the allocation of resources to improve outcome.
Source: Frontiers in Neurology - August 5, 2019 Category: Neurology Source Type: research

“A contemporary description of staphylococcus aureus prosthetic valve endocarditis. Differences according to the time elapsed from surgery”
Staphylococcus aureus prosthetic valve endocarditis (SAPVE) has a poor prognosis. There are no large series that accurately describe this entity. This is a retrospective observational study on a prospective cohort from 3 Spanish reference hospitals for cardiac surgery, including 78 definitive episodes of left SAPVE between 1996 and 2016. Fifty percent had a Charlson Index score>5; 53% were health care-related. Twenty percent did not present fever. Complications at diagnosis included: severe heart failure (HF, 29%), septic shock (SS, 17.9%), central nervous system abnormalities (19%), septic metastasis (4%). Hemorrhagic s...
Source: Medicine - August 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Prevalence, risk factors and outcomes of patients coming from the community with sepsis due to multidrug resistant bacteria
ConclusionIn light of the prevalence and impact of MDR bacteria causing sepsis in patients coming from the community, physicians should consider ESBL coverage when starting an empiric antibiotic therapy in patients with specific risk factors, especially in the presence of septic shock.
Source: Multidisciplinary Respiratory Medicine - July 4, 2019 Category: Respiratory Medicine Source Type: research

The predictive dysphagia score (PreDyScore) in the short- and medium-term post-stroke: a putative tool in PEG indication
ConclusionBMI<  20 and mRS ≥ 3 are easily measurable bedside predictive factors of persistent dysphagia. PreDyScore showed good sensitivity and very good specificity and enables the prediction of persistent dysphagia with great accuracy in any clinical setting.
Source: Neurological Sciences - April 18, 2019 Category: Neurology Source Type: research

Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke
ConclusionsEarly CBF response to mild HOB elevation in the ipsilesional hemisphere is related to functional outcome. Further studies may enable optical monitoring at the bedside to individualize management strategies in the early phase of AIS.
Source: Journal of Neurology - February 9, 2019 Category: Neurology Source Type: research

Safety of urgent endarterectomy in acute non ‐disabling stroke patients with symptomatic carotid artery stenosis: an international multicenter study
ConclusionsOur findings highlight that urgent CEA performed within two days from the index event is related to a non ‐significant increase in the risk of peri‐procedural stroke. The safety of urgent CEA requires further evaluation in larger datasets.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - November 25, 2018 Category: Neurology Authors: Andromachi Roussopoulou, Georgios Tsivgoulis, Christos Krogias, Andreas Lazaris, Konstantinos Moulakakis, George S. Georgiadis, Robert Mikulik, John D. Kakisis, Christina Zompola, Simon Faissner, Maria Chondrogianni, Chrissoula Liantinioti, Th Tags: Original Article Source Type: research

Efficacy and safety of direct aspiration versus stent-retriever for recanalization in acute cerebral infarction: A PRISMA-compliant systematic review and meta-analysis
Conclusions: The results support that the direct aspiration technique for those acute ischemic stroke patients may have better functional outcomes, less procedure related-adverse events and a tendency of faster revascularization time as compared to the stent-retriever thrombectomy, with a similar successful recanalization rate. However, major limitations of current evidence (mainly from retrospective and observational studies and a small number of patients population) indicate a need for adequately powered, multicenter randomized controlled trials (RCT) to answer this question.
Source: Medicine - October 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Clinical and radiological characteristics and predictors of outcome of cerebral venous sinus thrombosis, a hospital-based study
AbstractCerebral venous sinus thrombosis is an uncommon cause of stroke, which is more prevalent in Iran and the Middle East. We aimed to assess the etiology, radiologic, and clinical manifestations of cerebral venous sinus thrombosis, specifically the predictors of patients ’ outcome in Namazi hospital, Shiraz, Iran. In this retrospective study, we included all adult patients with the diagnosis of cerebral venous sinus thrombosis, who were admitted in hospital, from 2012 to 2016. Demographic data, radiologic findings, clinical presentation, risk factors, treatment, a nd outcome according to modified Rankin Scale (mRS) o...
Source: Acta Neurologica Belgica - September 3, 2018 Category: Neurology Source Type: research

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