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Helicobacter pylori infection: old and new.
Authors: Diaconu S, Predescu A, Moldoveanu A, Pop CS, Fierbințeanu-Braticevici C Abstract Helicobacter pylori is a spiral-shaped bacterium that grows in the digestive tract and may be present in more than half of the world's population. The clinical features of Helicobacter pylori range from asymptomatic gastritis to gastrointestinal malignancy. Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade B-cell marginal zone lymphoma and Helicobacter pylori has been detected in more than 75% of the patients with MALT lymphoma. Many tests for the detection of Helicobacter pylori are available, including antibo...
Source: Journal of Medicine and Life - June 17, 2017 Category: General Medicine Tags: J Med Life Source Type: research

Population attributable burden of Helicobacter pylori -related gastric cancer, coronary heart disease, and ischemic stroke in China
AbstractHelicobacter pylori, a risk factor of cancer and chronic diseases, remains highly prevalent in China. This review aims to systematically evaluate theH. pylori-attributable burden for gastric cancer (GC), coronary heart disease (CHD), and ischemic stroke (IS) in the Chinese population.Helicobacter pylori prevalence was updated by pooling the results reported in studies across China. The population attributable fraction (PAF) was calculated based on theH. pylori prevalence 10  years ago and relative risks of specific disease by reviewing the prospective studies published from 2000 through 2015. In China, the nationw...
Source: European Journal of Clinical Microbiology and Infectious Diseases - January 21, 2017 Category: Microbiology Source Type: research

Clinical Risk Factors for Gastroduodenal Ulcer in Romanian Low-Dose Aspirin Consumers.
Conclusions. Concomitant use of NSAIDs or anticoagulants, comorbidities (cerebrovascular disease), and male gender are the most important independent risk factors for ulcer on endoscopy in low-dose aspirin consumers, in a population with a high prevalence of H. pylori infection. PMID: 27579036 [PubMed]
Source: Gastroenterology Research and Practice - September 2, 2016 Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research

Top 20 Research Studies of 2015 for Primary Care Physicians.
This article, the fifth installment in this annual series, summarizes the 20 POEMs based on original research studies judged to have the greatest clinical relevance for family physicians. Key recommendations include questioning the need for backup throat cultures; avoiding early imaging and not adding cyclobenzaprine or oxycodone to naproxen for patients with acute low back pain; and encouraging patients with chronic or recurrent low back pain to walk. Other studies showed that using a nicotine patch for more than eight weeks has little benefit; that exercise can prevent falls that cause injury in at-risk older women; and ...
Source: American Family Physician - April 30, 2016 Category: Primary Care Authors: Ebell MH, Grad R Tags: Am Fam Physician Source Type: research

What Your Blood Type Means For Your Health
ImageContent(5627c16ae4b08589ef4a227d,5627c0981400006f003c8c87,Image,HectorAssetUrl(5627c0981400006f003c8c87,Some(crop_29_110_3211_2335),Some(jpeg)),AlexRaths via Getty Images,) EmbedContent(5627c16ae4b08589ef4a227e,SPECIAL FROM ,Embed,html,Some({})) Quick: What’s your blood type? If you’re scratching your head, you may be missing out on an important health clue. A spate of recent research suggests that your blood type—whether A, B, AB, or O—may influence your risk for a variety of health conditions, from cardiac disease to cancer.   The research is still early and scientists aren’t yet s...
Source: Healthy Living - The Huffington Post - October 25, 2015 Category: Consumer Health News Source Type: news

Estimates of benefits and harms of prophylactic use of aspirin in the general population
Conclusions Prophylactic aspirin use for a minimum of 5 years at doses between 75 and 325 mg/day appears to have favourable benefit–harm profile; longer use is likely to have greater benefits. Further research is needed to determine the optimum dose and duration of use, to identify individuals at increased risk of bleeding, and to test effectiveness of Helicobacter pylori screening–eradication before starting aspirin prophylaxis.
Source: Annals of Oncology - December 17, 2014 Category: Cancer & Oncology Authors: Cuzick, J., Thorat, M. A., Bosetti, C., Brown, P. H., Burn, J., Cook, N. R., Ford, L. G., Jacobs, E. J., Jankowski, J. A., La Vecchia, C., Law, M., Meyskens, F., Rothwell, P. M., Senn, H. J., Umar, A. Tags: reviews Source Type: research

Metabolic consequences of Helicobacter pylori infection and eradication.
Abstract Helicobacter pylori (H. pylori) is still the most prevalent infection of the world. Colonization of the stomach by this agent will invariably induce chronic gastritis which is a low-grade inflammatory state leading to local complications (peptic ulcer, gastric cancer, lymphoma) and remote manifestations. While H. pylori does not enter circulation, these extragastric manifestations are probably mediated by the cytokines and acute phase proteins produced by the inflammed mucosa. The epidemiologic link between the H. pylori infection and metabolic changes is inconstant and controversial. Growth delay was des...
Source: World Journal of Gastroenterology : WJG - May 14, 2014 Category: Gastroenterology Authors: Buzás GM Tags: World J Gastroenterol Source Type: research

The combination of Helicobacter pylori- and cytotoxin-associated gene-A seropositivity in relation to the risk of myocardial infarction in middle-aged Japanese: The Japan Public Health Center-based study
Conclusions: H. pylori infection was not significantly associated with risk of MI and stroke among middle-aged Japanese. However, CagA positivity tended to be associated with MI.Highlights:
Source: Atherosclerosis - September 1, 2013 Category: Cardiology Authors: Ai Ikeda, Hiroyasu Iso, Shizuka Sasazuki, Manami Inoue, Shoichiro Tsugane, for the JPHC Study Group Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research

H. Pylori May Protect Against Stroke
A new study by NYU School of Medicine researchers reveals that an especially virulent strain of the gut bacterium Helicobacter pylori (H. pylori) isn't implicated in the overall death rate of the U.S. population, and may even protect against stroke and some cancers. The findings, based a nationwide health survey of nearly 10,000 individuals over a period of some 12 years, were published online recently in the journal Gut. Those individuals carrying the most virulent strain of H...
Source: Health News from Medical News Today - January 10, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Disappearing bacterium may protect against stroke
(NYU Langone Medical Center / New York University School of Medicine) A new study by NYU School of Medicine researchers reveals that an especially virulent strain of the gut bacterium Helicobacter pylori isn't implicated in the overall death rate of the US population, and may even protect against stroke and some cancers.
Source: EurekAlert! - Medicine and Health - January 9, 2013 Category: Global & Universal Source Type: news